Prasanna, Variath, Bhattacharjya, Surajit, Balaram, Padmanabhan
Three synthetic peptides corresponding to distinct segments of the subunit interface of the dimeric enzyme thymidylate synthase (residues 17-38, N 22; residues 174-190, M 17; and residues 201-220, C...
Bhattacharjya, Surajit, Awasthi, Satish K, Adiga, Radhakantha P, Balaram, Padmanabhan
Riboflavin carrier protein (RCP) plays an important role in transporting vitamin B2 across placental membranes, a process critical for maintenance of pregnancy. Association of the vitamin with the...
Prasanna, Variath, Bhattacharjya, Surajit, Balaram, Padmanabhan
Three synthetic peptides corresponding to distinct segments of the subunit interface of the dimeric enzyme thymidylate synthase (residues 17-38, N 22; residues 174-190, M 17; and residues 201-220, C...
Bhattacharjya, Surajit, Awasthi, Satish K, Adiga, Radhakantha P, Balaram, Padmanabhan
Riboflavin carrier protein (RCP) plays an important role in transporting vitamin B2 across placental membranes, a process critical for maintenance of pregnancy. Association of the vitamin with the...
Bhattacharjya, Surajit, Balaram, P
A partly folded state of hen egg-white lysozyme has been characterized in 50% DMSO. Low concentrations of DMSO (10%) a cooperative transition of the structure to a new, partially folded state is...
Karle, IL, Pramanik, Animesh, Banerjee, Arindam, Bhattacharjya, Surajit, Balaram, P
Insertion of achiral \omega-amino acids into peptide sequences results in replacement of scissile peptide bonds by proteolytically stable C-C bonds. This provides a convenient means of creating...
Datta, Saumen, Shamala, N, Banerjee, Arindam, Pramanik, Animesh, Bhattacharjya, Surajit, Balaram, P
The Schellman motif is a widely observed, helix terminating structural motif in proteins, which is achieved by the adoption of a left-handed helical (alphaL) conformation by a C-terminus residue. The...
Rajan, Rahul, Awasthi, Satish K, Bhattacharjya, Surajit, Balaram, P
In the last 30 years, since the early work of Goodman and co-workers introducing trifluoroethanol as a solvent in peptide conformational analysis,1,2 the ability of fluoroalcohols to stabilize...
Bhattacharjya, Surajit, Balaram, Padmanabhan
A molten globule-like state of hen egg-white lysozyme has been characterized in 25% aqueous hexafluoroacetone hydrate (HFA) by CD, fluorescence, NMR, and H/D exchange experiments. The far UV CD...
Bhattacharjya, Surajit, David, Sunil A, Mathan, VI, Balaram, P
Polymyxin B nonapeptide (PMN) is a derivative of polymyxin B, an alpha, gamma-diaminobutyric acid-rich decapeptide from Bacillus polymyxa that displays antimicrobial and lipopolysaccharide...
Bhattacharjya, Surajit, Balaram, P
A partly folded state of hen egg-white lysozyme has been characterized in 50% DMSO. Low concentrations of DMSO (10%) a cooperative transition of the structure to a new, partially folded state is...
Karle, IL, Pramanik, Animesh, Banerjee, Arindam, Bhattacharjya, Surajit, Balaram, P
Insertion of achiral \omega-amino acids into peptide sequences results in replacement of scissile peptide bonds by proteolytically stable C-C bonds. This provides a convenient means of creating...
Datta, Saumen, Shamala, N, Banerjee, Arindam, Pramanik, Animesh, Bhattacharjya, Surajit, Balaram, P
The Schellman motif is a widely observed, helix terminating structural motif in proteins, which is achieved by the adoption of a left-handed helical (alphaL) conformation by a C-terminus residue. The...
Rajan, Rahul, Awasthi, Satish K, Bhattacharjya, Surajit, Balaram, P
In the last 30 years, since the early work of Goodman and co-workers introducing trifluoroethanol as a solvent in peptide conformational analysis,1,2 the ability of fluoroalcohols to stabilize...
Bhattacharjya, Surajit, Balaram, Padmanabhan
A molten globule-like state of hen egg-white lysozyme has been characterized in 25% aqueous hexafluoroacetone hydrate (HFA) by CD, fluorescence, NMR, and H/D exchange experiments. The far UV CD...
Bhattacharjya, Surajit, David, Sunil A, Mathan, VI, Balaram, P
Polymyxin B nonapeptide (PMN) is a derivative of polymyxin B, an alpha, gamma-diaminobutyric acid-rich decapeptide from Bacillus polymyxa that displays antimicrobial and lipopolysaccharide...
Omega Amino Acids in Peptide Design: Incorporation into Helices (1996)
Banerjee, Arindam, Pramanik, Animesh, Bhattacharjya, Surajit, Balaram, P
Incorporation of easily available achiral omega-amino acid residues into an oligopeptide results in substitution of amide bonds by polymethylene units of an aliphatic chain, thereby providing a...
Omega Amino Acids in Peptide Design: Incorporation into Helices (1996)
Banerjee, Arindam, Pramanik, Animesh, Bhattacharjya, Surajit, Balaram, P
Incorporation of easily available achiral omega-amino acid residues into an oligopeptide results in substitution of amide bonds by polymethylene units of an aliphatic chain, thereby providing a...
Solid State and Solution Conformations of a Helical Peptide with a Central Gly-Gly Segment (1996)
Karle, Isabella L, Banerjee, Arindam, Bhattacharjya, Surajit, Balaram, P
The influence of amino acids with contrasting con formational tendencies on the stereochemistry of oligopeptides has been investigated using an octapeptide Boc-Leu-Aib- Val-Gly-Gly-Leu-Aih-Val-OMe,...
Solid State and Solution Conformations of a Helical Peptide with a Central Gly-Gly Segment (1996)
Karle, Isabella L, Banerjee, Arindam, Bhattacharjya, Surajit, Balaram, P
The influence of amino acids with contrasting con formational tendencies on the stereochemistry of oligopeptides has been investigated using an octapeptide Boc-Leu-Aib- Val-Gly-Gly-Leu-Aih-Val-OMe,...
Bhattacharjya, Surajit, Xu, Ping, Chakrapani, Mukundan, Johnston, Linda, Ni, Feng
The sterile α-motif (SAM) is a protein module ~70 residues long and mainly involved in the protein–protein interactions of cell signaling and transcriptional repression. The SAM domain of the...
Bhattacharjya, Surajit, Xu, Ping, Xiang, Hui, Chrétien, Michel, Seidah, Nabil G., Ni, Feng
The endoprotease furin, which belongs to the family of mammalian proprotein convertase (PC), is synthesized as a zymogen with an N-terminal, 81-residue inhibitory prodomain. It has been shown that...