Suranjith L. Seneviratne

Allergen-specific CD8+ T cells and atopic disease

Seneviratne, Suranjith L., Jones, Louise, King, Abigail S., Black, Antony, Powell, Sheila, McMichael, Andrew J., ...

Considerable evidence suggests that IL-10 may have a role in the manifestation of atopic disease. We sought to test the hypothesis that at the single cell level, allergen-specific T cells have...

Longitudinal Analysis of CD8+ T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

Webster, George J. M., Reignat, Stephanie, Brown, David, Ogg, Graham S., Jones, Louise, Seneviratne, Suranjith L., ...

The cytotoxic T-cell response in chronic hepatitis B virus (HBV) infection has been described as weak and mono- or oligospecific in comparison to the more robust virus-specific T-cell response...

Allergen-specific CD8+ T cells and atopic disease

Seneviratne, Suranjith L., Jones, Louise, King, Abigail S., Black, Antony, Powell, Sheila, McMichael, Andrew J., ...

Considerable evidence suggests that IL-10 may have a role in the manifestation of atopic disease. We sought to test the hypothesis that at the single cell level, allergen-specific T cells have...

Longitudinal Analysis of CD8+ T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

Webster, George J. M., Reignat, Stephanie, Brown, David, Ogg, Graham S., Jones, Louise, Seneviratne, Suranjith L., ...

The cytotoxic T-cell response in chronic hepatitis B virus (HBV) infection has been described as weak and mono- or oligospecific in comparison to the more robust virus-specific T-cell response...

Interleukin-4 promotes human CD8+ T cell expression of CCR7

Seneviratne, Suranjith L, Black, Antony P, Jones, Louise, Di Gleria, Kati, Bailey, Abigail S, Ogg, Graham S

Despite strong evidence supporting a pathway of human T cell differentiation characterized by changes in the expression of CCR7, CD28, CD27 and CD62L, few studies have addressed the mechanisms of...

Escaping High Viral Load Exhaustion: CD8 Cells with Altered Tetramer Binding in Chronic Hepatitis B Virus Infection

Reignat, Stephanie, Webster, George J.M., Brown, David, Ogg, Graham S., King, Abigail, Seneviratne, Suranjith L., ...

Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in...