Suresh Yenugu

Identification, cloning and functional characterization of novel sperm associated antigen 11 (SPAG11) isoforms in the rat (2006)

Yenugu, Suresh, Hamil, Katherine G, Grossman, Gail, Petrusz, Peter, French, Frank S, Hall, Susan H

Abstract Background Sperm binding proteins and their C-terminal peptides of the Sperm Associated Antigen 11 (SPAG11) family were found to play an important role in epididymal innate immunity in...

Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus) (2006)

Yenugu, Suresh, Chintalgattu, Vishnu, Wingard, Christopher J, Radhakrishnan, Yashwanth, French, Frank S, Hall, Susan H

Abstract Background beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are predominantly expressed in...

Differential Expression and Antibacterial Activity of Epididymis Protein 2 Isoforms in the Male Reproductive Tract of Human and Rhesus Monkey (Macaca mulatta)1 (2004)

Maria Christina W. Avellar, Luciana Honda, Katherine G. Hamil, Suresh Yenugu, Gail Grossman, Peter Petrusz, ...

The epididymis protein 2 (EP2) gene, the fusion of two ancestral β-defensin genes, is highly expressed in the epididymis and subject to species-specific regulation at the levels of promoter...

Antimicrobial Activity of Human EPPIN, an Androgen-Regulated, Sperm-Bound Protein with a Whey Acidic Protein Motif1 (2004)

Suresh Yenugu, Richard T. Richardson, Perumal Sivashanmugam, Zengjun Wang, Michael G. O'Rand, Frank S. French, ...

The role of epididymal sperm-binding proteins in reproductive tract immunity is now well recognized in addition to their role in sperm maturation. Spermatozoa acquire forward motility and fertilizing...

Antimicrobial actions of the human epididymis 2 (HE2) protein isoforms, HE2alpha, HE2beta1 and HE2beta2 (2004)

Yenugu, Suresh, Hamil, Katherine G, French, Frank S, Hall, Susan H

Abstract Background The HE2 gene encodes a group of isoforms with similarities to the antimicrobial beta-defensins. We demonstrated earlier that the antimicrobial activity of HE2 proteins and...

LCN6, a novel human epididymal lipocalin (2003)

Hamil, Katherine G, Liu, Qiang, Sivashanmugam, P, Anbalagan, M, Yenugu, Suresh, Soundararajan, Rama, ...

Abstract Background The lipocalin (LCN) family of structurally conserved hydrophobic ligand binding proteins is represented in all major taxonomic groups from prokaryotes to primates. The importance...

Antibacterial properties of the sperm-binding proteins and peptides of human epididymis 2 (HE2) family; salt sensitivity, structural dependence and their interaction with outer and cytoplasmic membranes of Escherichia coli.

Yenugu, Suresh, Hamil, Katherine G, Birse, Charles E, Ruben, Steven M, French, Frank S, Hall, Susan H

During passage through the epididymis, sperm interact with secreted epididymal proteins that promote maturation, including the acquisition of motility and fertilization competence. Viewed previously...

Antibacterial properties of the sperm-binding proteins and peptides of human epididymis 2 (HE2) family; salt sensitivity, structural dependence and their interaction with outer and cytoplasmic membranes of Escherichia coli.

Yenugu, Suresh, Hamil, Katherine G, Birse, Charles E, Ruben, Steven M, French, Frank S, Hall, Susan H

During passage through the epididymis, sperm interact with secreted epididymal proteins that promote maturation, including the acquisition of motility and fertilization competence. Viewed previously...