Susan Carpenter

Pacific Symposium on Biocomputing 11:415-426(2006) IDENTIFYING INTERACTION SITES IN "RECALCITRANT" PROTEINS: PREDICTED PROTEIN AND RNA BINDING SITES IN REV PROTEINS OF HIV-1 AND EIAV AGREE WITH EXPERIMENTAL DATA (2009)

Michael Terribilini, Jae-hyung Lee, Changhui Yan, Robert L. Jernigan, Vasant Honavar, Drena Dobbs, ...

Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation of gene expression, protein synthesis, and replication and...

Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum (2009)

Maury, Wendy, Price, Jason P, Brindley, Melinda A, Oh, ChoonSeok, Neighbors, Jeffrey D, Wiemer, David F, ...

Abstract Background Light-dependent activities against enveloped viruses in St. John's Wort ( Hypericum perforatum ) extracts have been extensively studied. In contrast, light-independent antiviral...

Iowa State University (2008)

Justin Schonfeld, Susan Carpenter, Karin Dorman, Justin Schonfeld, Susan Carpenter, Karin Dorman, ...

A modular data analysis pipeline for the discovery of novel RNA motifs by

IDENTIFYING INTERACTION SITES IN "RECALCITRANT" PROTEINS: PREDICTED PROTEIN AND RNA BINDING SITES IN REV PROTEINS OF HIV-1 AND EIAV AGREE WITH EXPERIMENTAL DATA (2008)

Michael Terribilini, Jae-hyung Lee, Changhui Yan, L. Jernigan, Susan Carpenter, Vasant Honavar, ...

Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation of gene expression, protein synthesis, and replication and...

Characterization of Functional Domains of Equine Infectious Anemia Virus Rev Suggests a Bipartite RNA-Binding Domain (2006)

Lee, Jae-Hyung, Murphy, Sean C., Belshan, Michael, Sparks, Wendy O., Wannemuehler, Yvonne, Liu, Sijun, ...

Equine infectious anemia virus (EIAV) Rev is an essential regulatory protein that facilitates expression of viral mRNAs encoding structural proteins and genomic RNA and regulates alternative splicing...

Identifying Interaction Sites in "Recalcitrant" Proteins: Predicted Protein and Rna Binding Sites in Rev Proteins of Hiv-1 and Eiav Agree with Experimental Data (2005)

Terribilini, Michael, Lee, Jae-Hyung, Yan, Changhui, Jernigan, Robert L., Carpenter, Susan, Honavar, Vasant, ...

Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation of gene expression, protein synthesis, and replication and...

Hearing Levels of 416 Sonar Technicians (2005)

Marshall, Lynne, Carpenter, Susan

Audiograms for 416 sonar technicians were analyzed. Audiometric configurations were consistent with noise exposure. Nevertheless, The hearing of most sonar technicians was adequate for their job....

Subpopulations of Equine Infectious Anemia Virus Rev Coexist In Vivo and Differ in Phenotype (2003)

Baccam, Prasith, Thompson, Robert J., Li, Yuxing, Sparks, Wendy O., Belshan, Michael, Dorman, Karin S., ...

Lentiviruses exist in vivo as a population of related, nonidentical genotypes, commonly referred to as quasispecies. The quasispecies structure is characteristic of complex adaptive systems and...

Subpopulations of Equine Infectious Anemia Virus Rev Coexist In Vivo and Differ in Phenotype (2003)

Prasith Baccam, Robert J. Thompson, Yuxing Li, Wendy O. Sparks, Michael Belshan, Karin S. Dorman, ...

Lentiviruses exist in vivo as a population of related, nonidentical genotypes, commonly referred to as quasispecies. The quasispecies structure is characteristic of complex adaptive systems and...

Tumor Cell Toxicity of Hypericin and Related Analogs¶ (2001)

Nick J. Wills, Jaehun Park, Jin Wen, Sarathy Kesavan, George A. Kraus, Jacob W. Petrich, ...

A series of hypericin analogs were found to differ in their cytotoxic activity induced by ambient light levels. These analogs vary in their ability to partition into cells, to generate singlet oxygen...

Genetic and Biological Variation in Equine Infectious Anemia (2001)

Belshan, Michael, Baccum, Prasith, Oaks, J. Lindsay, Sponseller, Brett A., Murphy, Sean C., Cornette, James, ...

Genetic and biological variation in the regulatory protein Rev of equine infectious anemia virus (EIAV) were examined throughout a clinically dynamic disease course of an experimentally infected...

PAQ: Partition Analysis of Quasispecies (2001)

Baccam, Prasith, Thompson, Robert J., Fedrigo, Olivier, Carpenter, Susan, Cornette, James L.

Motivation: The complexities of genetic data may not be accurately described by any single analytical tool. Phylogenetic analysis is often used to study the genetic relationship among different...

Binding of Equine Infectious Anemia Virus Rev to an Exon Splicing Enhancer Mediates Alternative Splicing and Nuclear Export of Viral mRNAs (2000)

Belshan, Michael, Park, Gregory S., Bilodeau, Patricia, Stoltzfus, C. Martin, Carpenter, Susan

In addition to facilitating the nuclear export of incompletely spliced viral mRNAs, equine infectious anemia virus (EIAV) Rev regulates alternative splicing of the third exon of the tat/rev mRNA. In...

Temporary Auditory-Threshold Shifts Induced by Repeated Ten-Minute Exposures to Continuous Tones in Water. (1998)

Smith, Paul F., Wojtowicz, John, Carpenter, Susan

The purpose of this research is to develop a database upon which to establish hearing-conservation standards for Navy divers exposed to noise emanating from hand-held tools. Four divers were exposed...

Field Calibration of Two Types of Microphones in Hyperbaric Air. (1998)

Smith, Paul F., Carpenter, Susan, Green, John

The response of two microphones, one a condenser microphone and the other a diaphragm-activated piezoelectric ceramic microphone, were measured in compressed air at pressures as great as 810...

Biological Characterization of Rev Variation in Equine Infectious Anemia Virus (1998)

Belshan, Michael, Harris, Matthew E., Shoemaker, Anne E., Hope, Thomas J., Carpenter, Susan

Sequence analysis identified significant variation in the second exon of equine infectious anemia virus (EIAV) rev. Functional analysis indicated that limited amino acid variation in Rev...

Binding of Equine Infectious Anemia Virus Rev to an Exon Splicing Enhancer Mediates Alternative Splicing and Nuclear Export of Viral mRNAs

Belshan, Michael, Park, Gregory S., Bilodeau, Patricia, Stoltzfus, C. Martin, Carpenter, Susan

In addition to facilitating the nuclear export of incompletely spliced viral mRNAs, equine infectious anemia virus (EIAV) Rev regulates alternative splicing of the third exon of the tat/rev mRNA. In...

Biological Characterization of Rev Variation in Equine Infectious Anemia Virus

Belshan, Michael, Harris, Matthew E., Shoemaker, Anne E., Hope, Thomas J., Carpenter, Susan

Sequence analysis identified significant variation in the second exon of equine infectious anemia virus (EIAV) rev. Functional analysis indicated that limited amino acid variation in Rev...

Subpopulations of Equine Infectious Anemia Virus Rev Coexist In Vivo and Differ in Phenotype

Baccam, Prasith, Thompson, Robert J., Li, Yuxing, Sparks, Wendy O., Belshan, Michael, Dorman, Karin S., ...

Lentiviruses exist in vivo as a population of related, nonidentical genotypes, commonly referred to as quasispecies. The quasispecies structure is characteristic of complex adaptive systems and...

Raman Spectroscopy Detects Biochemical Changes Due to Proliferation in Mammalian Cell Cultures

Short, Kurt W., Carpenter, Susan, Freyer, James P., Mourant, Judith R.

Raman spectra of cells and nuclei from cultures in the plateau (nonproliferating) and exponential (proliferating) phases of growth were measured and show that Raman spectroscopy can monitor changes...

Characterization of Functional Domains of Equine Infectious Anemia Virus Rev Suggests a Bipartite RNA-Binding Domain

Lee, Jae-Hyung, Murphy, Sean C., Belshan, Michael, Sparks, Wendy O., Wannemuehler, Yvonne, Liu, Sijun, ...

Equine infectious anemia virus (EIAV) Rev is an essential regulatory protein that facilitates expression of viral mRNAs encoding structural proteins and genomic RNA and regulates alternative splicing...

Binding of Equine Infectious Anemia Virus Rev to an Exon Splicing Enhancer Mediates Alternative Splicing and Nuclear Export of Viral mRNAs

Belshan, Michael, Park, Gregory S., Bilodeau, Patricia, Stoltzfus, C. Martin, Carpenter, Susan

In addition to facilitating the nuclear export of incompletely spliced viral mRNAs, equine infectious anemia virus (EIAV) Rev regulates alternative splicing of the third exon of the tat/rev mRNA. In...

Biological Characterization of Rev Variation in Equine Infectious Anemia Virus

Belshan, Michael, Harris, Matthew E., Shoemaker, Anne E., Hope, Thomas J., Carpenter, Susan

Sequence analysis identified significant variation in the second exon of equine infectious anemia virus (EIAV) rev. Functional analysis indicated that limited amino acid variation in Rev...

Subpopulations of Equine Infectious Anemia Virus Rev Coexist In Vivo and Differ in Phenotype

Baccam, Prasith, Thompson, Robert J., Li, Yuxing, Sparks, Wendy O., Belshan, Michael, Dorman, Karin S., ...

Lentiviruses exist in vivo as a population of related, nonidentical genotypes, commonly referred to as quasispecies. The quasispecies structure is characteristic of complex adaptive systems and...

Raman Spectroscopy Detects Biochemical Changes Due to Proliferation in Mammalian Cell Cultures

Short, Kurt W., Carpenter, Susan, Freyer, James P., Mourant, Judith R.

Raman spectra of cells and nuclei from cultures in the plateau (nonproliferating) and exponential (proliferating) phases of growth were measured and show that Raman spectroscopy can monitor changes...

Characterization of Functional Domains of Equine Infectious Anemia Virus Rev Suggests a Bipartite RNA-Binding Domain

Lee, Jae-Hyung, Murphy, Sean C., Belshan, Michael, Sparks, Wendy O., Wannemuehler, Yvonne, Liu, Sijun, ...

Equine infectious anemia virus (EIAV) Rev is an essential regulatory protein that facilitates expression of viral mRNAs encoding structural proteins and genomic RNA and regulates alternative splicing...

Analysis of the EIAV Rev-Responsive Element (RRE) Reveals a Conserved RNA Motif Required for High Affinity Rev Binding in Both HIV-1 and EIAV

Lee, Jae-Hyung, Culver, Gloria, Carpenter, Susan, Dobbs, Drena

A cis-acting RNA regulatory element, the Rev-responsive element (RRE), has essential roles in replication of lentiviruses, including human immunodeficiency virus (HIV-1) and equine infection anemia...

Structural Model of the Rev Regulatory Protein from Equine Infectious Anemia Virus

Ihm, Yungok, Sparks, Wendy O., Lee, Jae-Hyung, Cao, Haibo, Carpenter, Susan, Wang, Cai-Zhuang, ...

Rev is an essential regulatory protein in the equine infectious anemia virus (EIAV) and other lentiviruses, including HIV-1. It binds incompletely spliced viral mRNAs and shuttles them from the...

Equine Infectious Anemia Virus Resists the Antiretroviral Activity of Equine APOBEC3 Proteins through a Packaging-Independent Mechanism▿

Bogerd, Hal P., Tallmadge, Rebecca L., Oaks, J. Lindsay, Carpenter, Susan, Cullen, Bryan R.

Equine infectious anemia virus (EIAV), uniquely among lentiviruses, does not encode a vif gene product. Other lentiviruses, including human immunodeficiency virus type 1 (HIV-1), use Vif to...