Application of phage display to high throughput antibody generation and characterization (2007)
Schofield, Darren J, Pope, Anthony R, Clementel, Veronica, Buckell, Jenny, Chapple, Susan DJ, Clarke, Kay F, ...
Abstract We have created a high quality phage display library containing over 10 10 human antibodies and describe its use in the generation of antibodies on an unprecedented scale. We have selected,...
Multiplexed expression and screening for recombinant protein production in mammalian cells (2006)
Chapple, Susan DJ, Crofts, Anna M, Shadbolt, S Paul, McCafferty, John, Dyson, Michael R
Abstract Background A variety of approaches to understanding protein structure and function require production of recombinant protein. Mammalian based expression systems have advantages over...
Multiplexed expression and screening for recombinant protein production in mammalian cells
Chapple, Susan DJ, Crofts, Anna M, Shadbolt, S Paul, McCafferty, John, Dyson, Michael R
Application of phage display to high throughput antibody generation and characterization
Schofield, Darren J, Pope, Anthony R, Clementel, Veronica, Buckell, Jenny, Chapple, Susan DJ, Clarke, Kay F, ...
A phage display library has been constructed containing over 1010 human antibodies, allowing the large-scale generation of antibodies. Over 38,000 recombinant antibodies against 292 antigens were...