Susan Gauthier

Dysregulated Inflammatory Response to Candida albicans in a C5-Deficient Mouse Strain†

Mullick, Alaka, Elias, Miria, Picard, Serge, Bourget, Lucie, Jovcevski, Orce, Gauthier, Susan, ...

Experimental infection of inbred mouse strains with Candida albicans provides a good model system to identify host genetic determinants that regulate onset of, response to, and ultimate outcome of...

Dysregulated Inflammatory Response to Candida albicans in a C5-Deficient Mouse Strain†

Mullick, Alaka, Elias, Miria, Picard, Serge, Bourget, Lucie, Jovcevski, Orce, Gauthier, Susan, ...

Experimental infection of inbred mouse strains with Candida albicans provides a good model system to identify host genetic determinants that regulate onset of, response to, and ultimate outcome of...

A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia–like syndrome in BXH-2 mice

Turcotte, Karine, Gauthier, Susan, Tuite, Ashleigh, Mullick, Alaka, Malo, Danielle, Gros, Philippe

BXH-2 mice develop a fatal myeloid leukemia by a two-step mutagenic process. First, a BXH-2–specific recessive mutation causes a myeloproliferative syndrome. Second, retroviral insertions alter...

The Iron Transport Protein NRAMP2 Is an Integral Membrane Glycoprotein That Colocalizes with Transferrin in Recycling Endosomes

Gruenheid, Samantha, Canonne-Hergaux, François, Gauthier, Susan, Hackam, David J., Grinstein, Sergio, Gros, Philippe

The natural resistance associated macrophage protein (Nramp) gene family is composed of two members in mammals, Nramp1 and Nramp2. Nramp1 is expressed primarily in macrophages and mutations at this...

Genetic interaction between members of the Vangl family causes neural tube defects in mice

Torban, Elena, Patenaude, Anne-Marie, Leclerc, Severine, Rakowiecki, Staci, Gauthier, Susan, Andelfinger, Gregor, ...

Neural tube defects (NTDs) are very frequent congenital abnormalities in humans. Recently, we have documented independent association of Vangl1 and Vangl2 gene mutations with NTDs. In the Looptail...