Susan J. Brown

Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps (2009)

Trauner, Jochen, Schinko, Johannes, Lorenzen, Marcé D, Shippy, Teresa D, Wimmer, Ernst A, Beeman, Richard W, ...

Abstract Background Given its sequenced genome and efficient systemic RNA interference response, the red flour beetle Tribolium castaneum is a model organism well suited for reverse genetics. Even...

Expression Data (2008)

Yi Lu, Shiyong Lu, Farshad Fotouhi, Youping Deng, Susan J. Brown

biology for gene expression data analysis. With the help of clustering algorithms such as Kmeans, hierarchical clustering, SOM, etc, genes are partitioned into groups based on the similarity between...

The genome of the model beetle and pest Tribolium castaneum (2008)

Gibbs, Richard A, Weinstock, George M, Brown, Susan J, Denell, Robin, Beeman, Richard W, ...

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural...

Analysis of repetitive DNA distribution patterns in the Tribolium castaneumgenome (2008)

Wang, Suzhi, Lorenzen, Marcé D, Beeman, Richard W, Brown, Susan J

Abstract Background Insect genomes vary widely in size, a large fraction of which is often devoted to repetitive DNA. Re-association kinetics indicate that up to 42% of the genome of the red flour...

The genome of the model beetle and pest Tribolium castaneum (2008)

Gibbs, Richard A., Weinstock, George M., Brown, Susan J., Denell, Robin, Beeman, Richard W., ...

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural...

BeetleBase: the model organism database for Tribolium castaneum (2007)

Wang, Liangjiang, Wang, Suzhi, Li, Yonghua, Paradesi, Martin S. R., Brown, Susan J.

BeetleBase (http://www.bioinformatics.ksu.edu/BeetleBase/) is an integrated resource for the Tribolium research community. The red flour beetle (Tribolium castaneum) is an important model organism...

Insights into social insects from the genome of the honeybee Apis mellifera (2006)

Robinson, Gene E, Gibbs, Richard A, Worley, Kim C, Evans, Jay D, Maleszka, Ryszard, ...

Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes,...

NIPARS: An Analysis of Procurement Performance and Cost for Nonstandard Items (2006)

Brown, Susan J.

In a world climate of declining defence budgets and contracting force structures, there is an increasing requirement for Australia to ensure value for money when undertaking defence purchases....

BindN: a web-based tool for efficient prediction of DNA and RNA binding sites in amino acid sequences (2006)

Wang, Liangjiang, Brown, Susan J.

BindN (http://bioinformatics.ksu.edu/bindn/) takes an amino acid sequence as input and predicts potential DNA or RNA-binding residues with support vector machines (SVMs). Protein datasets with known...

Patterns of conservation and change in honey bee developmental genes (2006)

Dearden, Peter K., Wilson, Megan J., Sablan, Lisha, Osborne, Peter W., Havler, Melanie, McNaughton, Euan, ...

The current insect genome sequencing projects provide an opportunity to extend studies of the evolution of developmental genes and pathways in insects. In this paper we examine the conservation and...

BeetleBase: the model organism database for Tribolium castaneum (2006)

Wang, Liangjiang, Wang, Suzhi, Li, Yonghua, Paradesi, Martin S. R., Brown, Susan J.

BeetleBase (http://www.bioinformatics.ksu.edu/BeetleBase/) is an integrated resource for the Tribolium research community. The red flour beetle (Tribolium castaneum) is an important model organism...

Patterns of conservation and change in honey bee developmental genes (2006)

Dearden, Peter K., Wilson, Megan J., Sablan, Lisha, Osborne, Peter W., Havler, Melanie, McNaughton, Euan, ...

The current insect genome sequencing projects provide an opportunity to extend studies of the evolution of developmental genes and pathways in insects. In this paper we examine the conservation and...

BeetleBase: the model organism database for Tribolium castaneum (2006)

Wang, Liangjiang, Wang, Suzhi, Li, Yonghua, Paradesi, Martin S. R., Brown, Susan J.

BeetleBase (http://www.bioinformatics.ksu.edu/BeetleBase/) is an integrated resource for the Tribolium research community. The red flour beetle (Tribolium castaneum) is an important model organism...

Incremental genetic K-means algorithm and its application in gene expression data analysis (2004)

Lu, Yi, Lu, Shiyong, Fotouhi, Farshad, Deng, Youping, Brown, Susan J

Abstract Background In recent years, clustering algorithms have been effectively applied in molecular biology for gene expression data analysis. With the help of clustering algorithms such as...

Computational identification of novel chitinase-like proteins in the Drosophila melanogaster genome (2004)

Zhu, Qingsong, Deng, Youping, Vanka, Phaneendra, Brown, Susan J., Muthukrishnan, Subbaratnam, Kramer, Karl J.

Motivation: Multiple chitinases as well as lectins closely related to them have been characterized previously from many insect species and the corresponding genes/cDNAs have been cloned. However, the...

Predicting hemolytic disease of the newborn with the monocyte-monolayer assay / (1995)

Brown, Susan J.

Thesis (M.S. in medical laboratory science)--University of Illinois at Chicago, 1995.

Genetic Control of Early Embryogenesis in the Red Flour Beetle, Tribolium castaneum (1994)

BROWN, SUSAN J., PARRISH, JANET K., DENELL, ROBIN E.

SYNOPSIS. The power of genetic analysis possible with the fruit fly, Drosophila melanogaster, has yielded a detailed understanding of pattern formation controlled by homeotic and segmentation genes...

Rhizobium trifolii 0403 Is Capable of Growth in the Absence of Combined Nitrogen †

Urban, James E., Davis, Lawrence C., Brown, Susan J.

Rhizobium trifolii 0403 was treated with 16.6 mM succinate and other nutrients and thereby induced to grow in nitrogen-free medium. The organism grew microaerophilically on either semisolid or liquid...

BindN: a web-based tool for efficient prediction of DNA and RNA binding sites in amino acid sequences

Wang, Liangjiang, Brown, Susan J.

BindN () takes an amino acid sequence as input and predicts potential DNA or RNA-binding residues with support vector machines (SVMs). Protein datasets with known DNA or RNA-binding residues were...

Gene Interactions Affecting Muscle Organization in CAENORHABDITIS ELEGANS

Brown, Susan J., Riddle, Donald L.

Revertants of unc-15(e73)I, a paralyzed mutant with an altered muscle paramyosin, include six dominant and two recessive intragenic unc-15 revertants, two new alleles of the previously identified...

Genetic Linkage Maps of the Red Flour Beetle, Tribolium castaneum, Based on Bacterial Artificial Chromosomes and Expressed Sequence Tags

Lorenzen, Marcé D., Doyungan, Zaldy, Savard, Joel, Snow, Kathy, Crumly, Lindsey R., Shippy, Teresa D., ...

A genetic linkage map was constructed in a backcross family of the red flour beetle, Tribolium castaneum, based largely on sequences from bacterial artificial chromosome (BAC) ends and untranslated...

Cloning and characterization of the Tribolium castaneum eye-color genes encoding tryptophan oxygenase and kynurenine 3-monooxygenase.

Lorenzen, Marcé D, Brown, Susan J, Denell, Robin E, Beeman, Richard W

The use of eye-color mutants and their corresponding genes as scorable marker systems has facilitated the development of transformation technology in Drosophila and other insects. In the red flour...

Sequence of the Tribolium castaneum homeotic complex: the region corresponding to the Drosophila melanogaster antennapedia complex.

Brown, Susan J, Fellers, John P, Shippy, Teresa D, Richardson, Elizabeth A, Maxwell, Mark, Stuart, Jeffery J, ...

The homeotic selector genes of the red flour beetle, Tribolium castaneum, are located in a single cluster. We have sequenced the region containing the homeotic selector genes required for proper...

A pair-rule gene circuit defines segments sequentially in the short-germ insect Tribolium castaneum

Choe, Chong Pyo, Miller, Sherry C., Brown, Susan J.

In Drosophila, a hierarchy of maternal, gap, pair-rule, and segment polarity gene interactions regulates virtually simultaneous blastoderm segmentation. For the last decade, studies have focused on...

The Tribolium castaneum Ortholog of Sex combs reduced Controls Dorsal Ridge Development

Shippy, Teresa D., Rogers, Carmelle D., Beeman, Richard W., Brown, Susan J., Denell, Robin E.

In insects, the boundary between the embryonic head and thorax is formed by the dorsal ridge, a fused structure composed of portions of the maxillary and labial segments. However, the mechanisms that...

Rhizobium trifolii 0403 Is Capable of Growth in the Absence of Combined Nitrogen †

Urban, James E., Davis, Lawrence C., Brown, Susan J.

Rhizobium trifolii 0403 was treated with 16.6 mM succinate and other nutrients and thereby induced to grow in nitrogen-free medium. The organism grew microaerophilically on either semisolid or liquid...

Gene Interactions Affecting Muscle Organization in CAENORHABDITIS ELEGANS

Brown, Susan J., Riddle, Donald L.

Revertants of unc-15(e73)I, a paralyzed mutant with an altered muscle paramyosin, include six dominant and two recessive intragenic unc-15 revertants, two new alleles of the previously identified...

Genetic Linkage Maps of the Red Flour Beetle, Tribolium castaneum, Based on Bacterial Artificial Chromosomes and Expressed Sequence Tags

Lorenzen, Marcé D., Doyungan, Zaldy, Savard, Joel, Snow, Kathy, Crumly, Lindsey R., Shippy, Teresa D., ...

A genetic linkage map was constructed in a backcross family of the red flour beetle, Tribolium castaneum, based largely on sequences from bacterial artificial chromosome (BAC) ends and untranslated...

Cloning and characterization of the Tribolium castaneum eye-color genes encoding tryptophan oxygenase and kynurenine 3-monooxygenase.

Lorenzen, Marcé D, Brown, Susan J, Denell, Robin E, Beeman, Richard W

The use of eye-color mutants and their corresponding genes as scorable marker systems has facilitated the development of transformation technology in Drosophila and other insects. In the red flour...

Sequence of the Tribolium castaneum homeotic complex: the region corresponding to the Drosophila melanogaster antennapedia complex.

Brown, Susan J, Fellers, John P, Shippy, Teresa D, Richardson, Elizabeth A, Maxwell, Mark, Stuart, Jeffery J, ...

The homeotic selector genes of the red flour beetle, Tribolium castaneum, are located in a single cluster. We have sequenced the region containing the homeotic selector genes required for proper...

BindN: a web-based tool for efficient prediction of DNA and RNA binding sites in amino acid sequences

Wang, Liangjiang, Brown, Susan J.

BindN () takes an amino acid sequence as input and predicts potential DNA or RNA-binding residues with support vector machines (SVMs). Protein datasets with known DNA or RNA-binding residues were...

A pair-rule gene circuit defines segments sequentially in the short-germ insect Tribolium castaneum

Choe, Chong Pyo, Miller, Sherry C., Brown, Susan J.

In Drosophila, a hierarchy of maternal, gap, pair-rule, and segment polarity gene interactions regulates virtually simultaneous blastoderm segmentation. For the last decade, studies have focused on...

The Tribolium castaneum Ortholog of Sex combs reduced Controls Dorsal Ridge Development

Shippy, Teresa D., Rogers, Carmelle D., Beeman, Richard W., Brown, Susan J., Denell, Robin E.

In insects, the boundary between the embryonic head and thorax is formed by the dorsal ridge, a fused structure composed of portions of the maxillary and labial segments. However, the mechanisms that...

BeetleBase: the model organism database for Tribolium castaneum

Wang, Liangjiang, Wang, Suzhi, Li, Yonghua, Paradesi, Martin S. R., Brown, Susan J.

BeetleBase () is an integrated resource for the Tribolium research community. The red flour beetle (Tribolium castaneum) is an important model organism for genetics, developmental biology, toxicology...

Patterns of conservation and change in honey bee developmental genes

Dearden, Peter K., Wilson, Megan J., Sablan, Lisha, Osborne, Peter W., Havler, Melanie, McNaughton, Euan, ...

The current insect genome sequencing projects provide an opportunity to extend studies of the evolution of developmental genes and pathways in insects. In this paper we examine the conservation and...

Hedgehog signaling pathway function conserved in Tribolium segmentation

Farzana, Laila, Brown, Susan J.

In Drosophila, maintenance of parasegmental boundaries and formation of segmental grooves depend on interactions between segment polarity genes. Wingless and Engrailed appear to have similar roles in...

Analysis of the Tribolium homeotic complex: insights into mechanisms constraining insect Hox clusters

Shippy, Teresa D., Ronshaugen, Matthew, Cande, Jessica, He, JianPing, Beeman, Richard W., Levine, Michael, ...

The remarkable conservation of Hox clusters is an accepted but little understood principle of biology. Some organizational constraints have been identified for vertebrate Hox clusters, but most of...

Do teashirt family genes specify trunk identity? Insights from the single tiptop/teashirt homolog of Tribolium castaneum

Shippy, Teresa D., Tomoyasu, Yoshinori, Nie, Wensheng, Brown, Susan J., Denell, Robin E.

The Drosophila teashirt gene acts in concert with the homeotic selector (Hox) genes to specify trunk (thorax and abdomen) identity. There has been speculation that this trunk-specifying function...

Analysis of repetitive DNA distribution patterns in the Tribolium castaneum genome

Wang, Suzhi, Lorenzen, Marcé D, Beeman, Richard W, Brown, Susan J

Approximately 30% of the Tribolium castaneum genome is comprised of repetitive DNA. These repeats accumulate in certain regions in the assembled T. castaneum genome, these regions might be derived...