Susan K. H. Gillespie

A Chemical-Genetic Strategy Implicates Myosin-1c in Adaptation by Hair Cells

Holt, Jeffrey R., Gillespie, Susan K.H., Provance, D. William, Shah, Kavita, Shokat, Kevan M., Corey, David P., ...

Myosin-1c (also known as myosin-Iβ) has been proposed to mediate the slow component of adaptation by hair cells, the sensory cells of the inner ear. To test this hypothesis, we mutated tyrosine-61...