Efficient labeling of fission yeast Schizosaccharomyces pombe with thymidine and BUdR (2003)
Hodson, Jeffrey A., Bailis, Julie M., Forsburg, Susan L.
In this paper we report the construction of a Schizosaccharomyces pombe strain that facilitates analysis of replicating DNA. The strain co‐expresses the Herpes simplex virus thymidine kinase...
RNAi hushes heterochromatin (2002)
Bailis, Julie M, Forsburg, Susan L
Abstract Repeated DNA elements and region-specific protein modifications combine within chromosomes to form a transcriptionally silent chromatin structure called heterochromatin. Recent work in the...
Fission yeast enters a joyful new era (2002)
Gómez, Eliana B, Bailis, Julie M, Forsburg, Susan L
A report on the Second International Fission Yeast Meeting, Kyoto, Japan, 25-30 March 2002.
Pasion, Sally G, Gómez, Eliana B, Forsburg, Susan L
A report on the sixth biannual FASEB conference on Yeast Chromosome Structure, Replication and Segregation held in Snowmass, Colorado, 19-24 August, 2000.
Bishop, Danielle T., McDonald, W. Hayes, Gould, Kathleen L., Forsburg, Susan L.
We carried out a screen for mutants that arrest prior to premeiotic S phase. One of the strains we isolated contains a temperature-sensitive allele mutation in the fission yeast prp31+ gene. The...
Sherman, Daniel A., Pasion, Sally G., Forsburg, Susan L.
The members of the MCM protein family are essential eukaryotic DNA replication factors that form a six-member protein complex. In this study, we use antibodies to four MCM proteins to investigate the...
Bezanilla, Magdalena, Forsburg, Susan L., Pollard, Thomas D.
As in many eukaryotic cells, fission yeast cytokinesis depends on the assembly of an actin ring. We cloned myp2+, a myosin-II in Schizosaccharomyces pombe, conditionally required for cytokinesis....
Nuclear Localization of Schizosaccharomyces pombe Mcm2/Cdc19p Requires MCM Complex Assembly
Pasion, Sally G., Forsburg, Susan L.
The minichromosome maintenance (MCM) proteins MCM2–MCM7 are conserved eukaryotic replication factors that assemble in a heterohexameric complex. In fission yeast, these proteins are nuclear...
Schizosaccharomyces pombe Hsk1p Is a Potential Cds1p Target Required for Genome Integrity
Snaith, Hilary A., Brown, Grant W., Forsburg, Susan L.
The fission yeast Hsk1p kinase is an essential activator of DNA replication. Here we report the isolation and characterization of a novel mutant allele of the gene. Consistent with its role in the...
Leverson, Joel D., Huang, Han-kuei, Forsburg, Susan L., Hunter, Tony
The chromosomal passenger proteins aurora-B, survivin, and inner centromere protein (INCENP) have been implicated in coordinating chromosome segregation with cell division. This work describes the...
Isolation of an essential Schizosaccharomyces pombe gene, prp31+, that links splicing and meiosis
Bishop, Danielle T., McDonald, W. Hayes, Gould, Kathleen L., Forsburg, Susan L.
We carried out a screen for mutants that arrest prior to premeiotic S phase. One of the strains we isolated contains a temperature-sensitive allele mutation in the fission yeast prp31+ gene. The...
Pasion, Sally G, Gómez, Eliana B, Forsburg, Susan L
A report on the sixth biannual FASEB conference on Yeast Chromosome Structure, Replication and Segregation held in Snowmass, Colorado, 19-24 August, 2000.
Fission yeast enters a joyful new era
Gómez, Eliana B, Bailis, Julie M, Forsburg, Susan L
A report on the Second International Fission Yeast Meeting, Kyoto, Japan, 25-30 March 2002.
Bailis, Julie M, Forsburg, Susan L
Recent work in the fission yeast Schizosaccharomyces pombe reveals that RNA is an integral component of silent heterochromatin.
Catlett, Michael G., Forsburg, Susan L.
We report the characterization of rdh54+, the second fission yeast Schizosaccharomyces pombe Rad54 homolog. rdh54+ shares sequence and functional homology to budding yeast RDH54/TID1. Rdh54p is...
Efficient labeling of fission yeast Schizosaccharomyces pombe with thymidine and BUdR
Hodson, Jeffrey A., Bailis, Julie M., Forsburg, Susan L.
In this paper we report the construction of a Schizosaccharomyces pombe strain that facilitates analysis of replicating DNA. The strain co-expresses the Herpes simplex virus thymidine kinase gene...
Eukaryotic MCM Proteins: Beyond Replication Initiation
The minichromosome maintenance (or MCM) protein family is composed of six related proteins that are conserved in all eukaryotes. They were first identified by genetic screens in yeast and...
Meiotic S-Phase Damage Activates Recombination without Checkpoint ArrestD⃞
Pankratz, Daniel G., Forsburg, Susan L.
Checkpoints operate during meiosis to ensure the completion of DNA synthesis and programmed recombination before the initiation of meiotic divisions. Studies in the fission yeast Schizosaccharomyces...
Huang, Han-Kuei, Bailis, Julie M., Leverson, Joel D., Gómez, Eliana B., Forsburg, Susan L., Hunter, Tony
Fission yeast Bir1p/Cut17p/Pbh1p, the homolog of human Survivin, is a conserved chromosomal passenger protein that is required for cell division and cytokinesis. To study how Bir1p promotes accurate...
Gómez, Eliana B., Espinosa, Joaquín M., Forsburg, Susan L.
Histone acetylation and deacetylation are associated with transcriptional activity and the formation of constitutively silent heterochromatin. Increasingly, histone acetylation is also implicated in...
Gómez, Eliana B., Angeles, Vanessa T., Forsburg, Susan L.
Fission yeast mutants defective in DNA replication have widely varying morphological phenotypes. We designed a screen for temperature-sensitive mutants defective in the process of replication...
Conserved Locus-Specific Silencing Functions of Schizosaccharomyces pombe sir2+
Freeman-Cook, Lisa L., Gómez, Eliana B., Spedale, Erik J., Marlett, John, Forsburg, Susan L., Pillus, Lorraine, ...
In Schizosaccharomyces pombe, three genes, sir2+, hst2+, and hst4+, encode members of the Sir2 family of conserved NAD+-dependent protein deacetylases. The S. pombe sir2+ gene encodes a nuclear...
Gómez, Eliana B, Catlett, Michael G, Forsburg, Susan L
The six conserved MCM proteins are essential for normal DNA replication. They share a central core of homology that contains sequences related to DNA-dependent and AAA(+) ATPases. It has been...
Sherman, Daniel A., Pasion, Sally G., Forsburg, Susan L.
The members of the MCM protein family are essential eukaryotic DNA replication factors that form a six-member protein complex. In this study, we use antibodies to four MCM proteins to investigate the...
Bezanilla, Magdalena, Forsburg, Susan L., Pollard, Thomas D.
As in many eukaryotic cells, fission yeast cytokinesis depends on the assembly of an actin ring. We cloned myp2+, a myosin-II in Schizosaccharomyces pombe, conditionally required for cytokinesis....
Nuclear Localization of Schizosaccharomyces pombe Mcm2/Cdc19p Requires MCM Complex Assembly
Pasion, Sally G., Forsburg, Susan L.
The minichromosome maintenance (MCM) proteins MCM2–MCM7 are conserved eukaryotic replication factors that assemble in a heterohexameric complex. In fission yeast, these proteins are nuclear...
Schizosaccharomyces pombe Hsk1p Is a Potential Cds1p Target Required for Genome Integrity
Snaith, Hilary A., Brown, Grant W., Forsburg, Susan L.
The fission yeast Hsk1p kinase is an essential activator of DNA replication. Here we report the isolation and characterization of a novel mutant allele of the gene. Consistent with its role in the...
Leverson, Joel D., Huang, Han-kuei, Forsburg, Susan L., Hunter, Tony
The chromosomal passenger proteins aurora-B, survivin, and inner centromere protein (INCENP) have been implicated in coordinating chromosome segregation with cell division. This work describes the...
Isolation of an essential Schizosaccharomyces pombe gene, prp31+, that links splicing and meiosis
Bishop, Danielle T., McDonald, W. Hayes, Gould, Kathleen L., Forsburg, Susan L.
We carried out a screen for mutants that arrest prior to premeiotic S phase. One of the strains we isolated contains a temperature-sensitive allele mutation in the fission yeast prp31+ gene. The...
Pasion, Sally G, Gómez, Eliana B, Forsburg, Susan L
A report on the sixth biannual FASEB conference on Yeast Chromosome Structure, Replication and Segregation held in Snowmass, Colorado, 19-24 August, 2000.
Fission yeast enters a joyful new era
Gómez, Eliana B, Bailis, Julie M, Forsburg, Susan L
A report on the Second International Fission Yeast Meeting, Kyoto, Japan, 25-30 March 2002.
Bailis, Julie M, Forsburg, Susan L
Recent work in the fission yeast Schizosaccharomyces pombe reveals that RNA is an integral component of silent heterochromatin.
Catlett, Michael G., Forsburg, Susan L.
We report the characterization of rdh54+, the second fission yeast Schizosaccharomyces pombe Rad54 homolog. rdh54+ shares sequence and functional homology to budding yeast RDH54/TID1. Rdh54p is...
Efficient labeling of fission yeast Schizosaccharomyces pombe with thymidine and BUdR
Hodson, Jeffrey A., Bailis, Julie M., Forsburg, Susan L.
In this paper we report the construction of a Schizosaccharomyces pombe strain that facilitates analysis of replicating DNA. The strain co-expresses the Herpes simplex virus thymidine kinase gene...
Eukaryotic MCM Proteins: Beyond Replication Initiation
The minichromosome maintenance (or MCM) protein family is composed of six related proteins that are conserved in all eukaryotes. They were first identified by genetic screens in yeast and...
Meiotic S-Phase Damage Activates Recombination without Checkpoint ArrestD⃞
Pankratz, Daniel G., Forsburg, Susan L.
Checkpoints operate during meiosis to ensure the completion of DNA synthesis and programmed recombination before the initiation of meiotic divisions. Studies in the fission yeast Schizosaccharomyces...
Huang, Han-Kuei, Bailis, Julie M., Leverson, Joel D., Gómez, Eliana B., Forsburg, Susan L., Hunter, Tony
Fission yeast Bir1p/Cut17p/Pbh1p, the homolog of human Survivin, is a conserved chromosomal passenger protein that is required for cell division and cytokinesis. To study how Bir1p promotes accurate...
Gómez, Eliana B., Espinosa, Joaquín M., Forsburg, Susan L.
Histone acetylation and deacetylation are associated with transcriptional activity and the formation of constitutively silent heterochromatin. Increasingly, histone acetylation is also implicated in...
Gómez, Eliana B., Angeles, Vanessa T., Forsburg, Susan L.
Fission yeast mutants defective in DNA replication have widely varying morphological phenotypes. We designed a screen for temperature-sensitive mutants defective in the process of replication...
Conserved Locus-Specific Silencing Functions of Schizosaccharomyces pombe sir2+
Freeman-Cook, Lisa L., Gómez, Eliana B., Spedale, Erik J., Marlett, John, Forsburg, Susan L., Pillus, Lorraine, ...
In Schizosaccharomyces pombe, three genes, sir2+, hst2+, and hst4+, encode members of the Sir2 family of conserved NAD+-dependent protein deacetylases. The S. pombe sir2+ gene encodes a nuclear...
Gómez, Eliana B, Catlett, Michael G, Forsburg, Susan L
The six conserved MCM proteins are essential for normal DNA replication. They share a central core of homology that contains sequences related to DNA-dependent and AAA(+) ATPases. It has been...
Bailis, Julie M., Luche, Douglas D., Hunter, Tony, Forsburg, Susan L.
The minichromosome maintenance (MCM) complex plays essential, conserved roles throughout DNA synthesis: first, as a component of the prereplication complex at origins and, then, as a helicase...
Gómez, Eliana B., Nugent, Rebecca L., Laria, Sebastián, Forsburg, Susan L.
Schizosaccharomyces pombe Mst1 is a member of the MYST family of histone acetyltransferases and is the likely ortholog of Saccharomyces cerevisiae Esa1 and human Tip60 (KAT5). We have isolated a...