Parkinson's disease: from monogenic forms to genetic susceptibility factors (2009)
Lesage, Suzanne, Brice, Alexis
Research in Parkinson's disease (PD) genetics has been extremely prolific over the past decade. More than 13 loci and 9 genes have been identified, but their implication in PD is not always certain....
Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa (2006)
Ibáñez, Pablo, Lesage, Suzanne, Lohmann, Ebba, Thobois, Stéphane, Michele, Giuseppe De, Borg, Michel, ...
Parkinson's disease is a frequent disorder caused primarily by the loss of dopaminergic neurons of the substantia nigra. Mutations in the PTEN-induced kinase (PINK1) gene, in addition to those in...
Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa (2006)
Ibáñez, Pablo, Lesage, Suzanne, Lohmann, Ebba, Thobois, Stéphane, De Michele, Giuseppe, Borg, Michel, ...
Parkinson's disease is a frequent disorder caused primarily by the loss of dopaminergic neurons of the substantia nigra. Mutations in the PTEN-induced kinase (PINK1) gene, in addition to those in...
Significant linkage to spondyloarthropathy on 9q31-34 (2004)
Miceli-Richard, Corinne, Zouali, Habib, Said-Nahal, Roula, Lesage, Suzanne, Merlin, Françoise, De Toma, Claudia, ...
Spondyloarthropathy (SpA) is a frequent rheumatologic disorder with a prevalence of 0.3% in Caucasian populations from western Europe. It commonly presents as chronic axial and/or peripheral...
Includes abstracts in English and French.
Synthesis and stereochemistry of unsaturated lactones related to fungal metabolites / (1977)
Written for the Dept. of Chemistry.
Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases
Chamaillard, Mathias, Philpott, Dana, Girardin, Stephen E., Zouali, Habib, Lesage, Suzanne, Chareyre, Fabrice, ...
CARD15 is a major susceptibility gene for a frequent multifactorial chronic inflammatory bowel disorder, Crohn disease (CD). By using NF-κB activation assays, the cytosolic CARD15 was shown to...
Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases
Chamaillard, Mathias, Philpott, Dana, Girardin, Stephen E., Zouali, Habib, Lesage, Suzanne, Chareyre, Fabrice, ...
CARD15 is a major susceptibility gene for a frequent multifactorial chronic inflammatory bowel disorder, Crohn disease (CD). By using NF-κB activation assays, the cytosolic CARD15 was shown to...
Lesage, Suzanne, Zouali, Habib, Cézard, Jean-Pierre, Colombel, Jean-Frédéric, Belaiche, Jacques, Almer, Sven, ...
CARD15/NOD2 encodes a protein involved in bacterial recognition by monocytes. Mutations in CARD15 have recently been found in patients with Crohn disease (CD), a chronic inflammatory condition of the...