Lahousse, Stephanie A, Carter, Jade J, Xu, Xaolai J, Wands, Jack R, De La Monte, Suzanne M
Abstract Background Aspartyl (asparaginyl)-β-hydroxylase (AAH) hydroxylates Asp and Asn residues within EGF-like domains of Notch and Jagged, which mediate cell motility and differentiation. This...
Bloch, Donald B., Nakajima, Ayako, Gulick, Tod, Chiche, Jean-Daniel, Orth, Donald, De La Monte, Suzanne M., ...
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This structure is disrupted in a variety of human disorders including acute promyelocytic...
Properties of Monoclonal Antibodies Directed against Hepatitis B Virus Polymerase Protein
Zu Putlitz, Jasper, Lanford, Robert E., Carlson, Rolf I., Notvall, Lena, De La Monte, Suzanne M., Wands, Jack R.
Hepadnavirus polymerases are multifunctional enzymes that play critical roles during the viral life cycle but have been difficult to study due to a lack of a well-defined panel of monoclonal...
Structural and Functional Heterogeneity of Nuclear Bodies
Bloch, Donald B., Chiche, Jean-Daniel, Orth, Donald, De La Monte, Suzanne M., Rosenzweig, Anthony, Bloch, Kenneth D.
The nuclear body is a cellular structure that appears to be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. In addition, the nuclear body is a target of...
Bloch, Donald B., Nakajima, Ayako, Gulick, Tod, Chiche, Jean-Daniel, Orth, Donald, De La Monte, Suzanne M., ...
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This structure is disrupted in a variety of human disorders including acute promyelocytic...
Properties of Monoclonal Antibodies Directed against Hepatitis B Virus Polymerase Protein
Zu Putlitz, Jasper, Lanford, Robert E., Carlson, Rolf I., Notvall, Lena, De La Monte, Suzanne M., Wands, Jack R.
Hepadnavirus polymerases are multifunctional enzymes that play critical roles during the viral life cycle but have been difficult to study due to a lack of a well-defined panel of monoclonal...
Structural and Functional Heterogeneity of Nuclear Bodies
Bloch, Donald B., Chiche, Jean-Daniel, Orth, Donald, De La Monte, Suzanne M., Rosenzweig, Anthony, Bloch, Kenneth D.
The nuclear body is a cellular structure that appears to be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. In addition, the nuclear body is a target of...
The Liver-Brain Axis of Alcohol-Mediated Neurodegeneration: Role of Toxic Lipids
De La Monte, Suzanne M., Longato, Lisa, Tong, Ming, DeNucci, Sarah, Wands, Jack R.
Alcohol abuse causes progressive toxicity and degeneration in liver and brain due to insulin resistance, which exacerbates oxidative stress and pro-inflammatory cytokine activation. Alcohol-induced...
Alzheimer's Disease Is Type 3 Diabetes–Evidence Reviewed
De La Monte, Suzanne M., Wands, Jack R.
Alzheimer's disease (AD) has characteristic histopathological, molecular, and biochemical abnormalities, including cell loss; abundant neurofibrillary tangles; dystrophic neurites; amyloid precursor...