Suzanne M. Sebald

Characterization of Growth-Differentiation Factor 15, a Transforming Growth Factor β Superfamily Member Induced following Liver Injury

Hsiao, Edward C., Koniaris, Leonidas G., Zimmers-Koniaris, Teresa, Sebald, Suzanne M., Huynh, Thanh V., Lee, Se-Jin

We have identified a new murine transforming growth factor β superfamily member, growth-differentiation factor 15 (Gdf15), that is expressed at highest levels in adult liver. As determined by...

Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases

Wolfman, Neil M., McPherron, Alexandra C., Pappano, William N., Davies, Monique V., Song, Kening, Tomkinson, Kathleen N., ...

Myostatin is a transforming growth factor β family member that acts as a negative regulator of skeletal muscle growth. Myostatin circulates in the blood of adult mice in a noncovalently held complex...

Regulation of muscle growth by multiple ligands signaling through activin type II receptors

Lee, Se-Jin, Reed, Lori A., Davies, Monique V., Girgenrath, Stefan, Goad, Mary E. P., Tomkinson, Kathy N., ...

Myostatin is a secreted protein that normally functions as a negative regulator of muscle growth. Agents capable of blocking the myostatin signaling pathway could have important applications for...

Characterization of Growth-Differentiation Factor 15, a Transforming Growth Factor β Superfamily Member Induced following Liver Injury

Hsiao, Edward C., Koniaris, Leonidas G., Zimmers-Koniaris, Teresa, Sebald, Suzanne M., Huynh, Thanh V., Lee, Se-Jin

We have identified a new murine transforming growth factor β superfamily member, growth-differentiation factor 15 (Gdf15), that is expressed at highest levels in adult liver. As determined by...

Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases

Wolfman, Neil M., McPherron, Alexandra C., Pappano, William N., Davies, Monique V., Song, Kening, Tomkinson, Kathleen N., ...

Myostatin is a transforming growth factor β family member that acts as a negative regulator of skeletal muscle growth. Myostatin circulates in the blood of adult mice in a noncovalently held complex...

Regulation of muscle growth by multiple ligands signaling through activin type II receptors

Lee, Se-Jin, Reed, Lori A., Davies, Monique V., Girgenrath, Stefan, Goad, Mary E. P., Tomkinson, Kathy N., ...

Myostatin is a secreted protein that normally functions as a negative regulator of muscle growth. Agents capable of blocking the myostatin signaling pathway could have important applications for...