Sven Bogaerts

G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv. (2005)

Doumont, Gilles, Martoriati, Alain, Beekman, Chantal, Bogaerts, Sven, Mee, Patrick J, Bureau, Fabrice, ...

In response to DNA damage, p53 activates a G1 cell cycle checkpoint, in part through induction of the cyclin-dependent kinase inhibitor p21(Waf1/Cip1). Here we report the identification of a new...

G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv

Doumont, Gilles, Martoriati, Alain, Beekman, Chantal, Bogaerts, Sven, Mee, Patrick J, Bureau, Fabrice, ...

In response to DNA damage, p53 activates a G1 cell cycle checkpoint, in part through induction of the cyclin-dependent kinase inhibitor p21(Waf1/Cip1). Here we report the identification of a new...

Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo

Francoz, Sarah, Froment, Pascal, Bogaerts, Sven, De Clercq, Sarah, Maetens, Marion, Doumont, Gilles, ...

The Mdm2 and Mdm4 oncoproteins are key negative regulators of the p53 tumor suppressor. However, their physiological contributions to the regulation of p53 stability and activity remain highly...

G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv

Doumont, Gilles, Martoriati, Alain, Beekman, Chantal, Bogaerts, Sven, Mee, Patrick J, Bureau, Fabrice, ...

In response to DNA damage, p53 activates a G1 cell cycle checkpoint, in part through induction of the cyclin-dependent kinase inhibitor p21(Waf1/Cip1). Here we report the identification of a new...

Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo

Francoz, Sarah, Froment, Pascal, Bogaerts, Sven, De Clercq, Sarah, Maetens, Marion, Doumont, Gilles, ...

The Mdm2 and Mdm4 oncoproteins are key negative regulators of the p53 tumor suppressor. However, their physiological contributions to the regulation of p53 stability and activity remain highly...