Svetlana Radaeva

Opposing roles of STAT1 and STAT3 in T cell–mediated hepatitis: regulation by SOCS

Hong, Feng, Jaruga, Barbara, Kim, Won Ho, Radaeva, Svetlana, El-Assal, Osama N., Tian, Zhigang, ...

T cell–mediated fulminant hepatitis is a life-threatening event for which the underlying mechanism is not fully understood. Injection of concanavalin A (Con A) into mice recapitulates the...

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

Osei-Hyiaman, Douglas, DePetrillo, Michael, Pacher, Pál, Liu, Jie, Radaeva, Svetlana, Bátkai, Sándor, ...

Endogenous cannabinoids acting at CB1 receptors stimulate appetite, and CB1 antagonists show promise in the treatment of obesity. CB1–/– mice are resistant to diet-induced obesity even though...

Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.

Radaeva, Svetlana, Jaruga, Barbara, Kim, Won-Ho, Heller, Theo, Liang, T Jake, Gao, Bin

IFN-gamma (interferon-gamma) modulates IFN-alpha therapy in chronic hepatitis C infection; however, the underlying mechanism remains unclear. Here we demonstrate that long-term (3-6 days) but not...

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice

Xu, Xiaoling, Kobayashi, Shogo, Qiao, Wenhui, Li, Cuiling, Xiao, Cuiying, Radaeva, Svetlana, ...

Cholangiocellular carcinoma (CC), the second most common primary liver cancer, is associated with a poor prognosis. It has been shown that CCs harbor alterations of a number of tumor-suppressor genes...

Opposing roles of STAT1 and STAT3 in T cell–mediated hepatitis: regulation by SOCS

Hong, Feng, Jaruga, Barbara, Kim, Won Ho, Radaeva, Svetlana, El-Assal, Osama N., Tian, Zhigang, ...

T cell–mediated fulminant hepatitis is a life-threatening event for which the underlying mechanism is not fully understood. Injection of concanavalin A (Con A) into mice recapitulates the...

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

Osei-Hyiaman, Douglas, DePetrillo, Michael, Pacher, Pál, Liu, Jie, Radaeva, Svetlana, Bátkai, Sándor, ...

Endogenous cannabinoids acting at CB1 receptors stimulate appetite, and CB1 antagonists show promise in the treatment of obesity. CB1–/– mice are resistant to diet-induced obesity even though...

Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.

Radaeva, Svetlana, Jaruga, Barbara, Kim, Won-Ho, Heller, Theo, Liang, T Jake, Gao, Bin

IFN-gamma (interferon-gamma) modulates IFN-alpha therapy in chronic hepatitis C infection; however, the underlying mechanism remains unclear. Here we demonstrate that long-term (3-6 days) but not...

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice

Xu, Xiaoling, Kobayashi, Shogo, Qiao, Wenhui, Li, Cuiling, Xiao, Cuiying, Radaeva, Svetlana, ...

Cholangiocellular carcinoma (CC), the second most common primary liver cancer, is associated with a poor prognosis. It has been shown that CCs harbor alterations of a number of tumor-suppressor genes...