Sweta Patel

αADα Hybrids of Cryptococcus neoformans: Evidence of Same-Sex Mating in Nature and Hybrid Fitness (2007)

Xiaorong Lin, Anastasia P. Litvintseva, Kirsten Nielsen, Sweta Patel, Anna Floyd, Thomas G. Mitchell, ...

Cryptococcus neoformans is a ubiquitous human fungal pathogen that causes meningoencephalitis in predominantly immunocompromised hosts. The fungus is typically haploid, and sexual reproduction...

αADα Hybrids of Cryptococcus neoformans: Evidence of Same-Sex Mating in Nature and Hybrid Fitness

Lin, Xiaorong, Litvintseva, Anastasia P, Nielsen, Kirsten, Patel, Sweta, Floyd, Anna, Mitchell, Thomas G, ...

Cryptococcus neoformans is a ubiquitous human fungal pathogen that causes meningoencephalitis in predominantly immunocompromised hosts. The fungus is typically haploid, and sexual reproduction...

Impact of Mating Type, Serotype, and Ploidy on the Virulence of Cryptococcus neoformans▿ †

Lin, Xiaorong, Nielsen, Kirsten, Patel, Sweta, Heitman, Joseph

Hybridization with polyploidization is a significant biological force driving evolution. The effect of combining two distinct genomes in one organism on the virulence potential of pathogenic fungi is...

Diploids in the Cryptococcus neoformans Serotype A Population Homozygous for the α Mating Type Originate via Unisexual Mating

Lin, Xiaorong, Patel, Sweta, Litvintseva, Anastasia P., Floyd, Anna, Mitchell, Thomas G., Heitman, Joseph

The ubiquitous environmental human pathogen Cryptococcus neoformans is traditionally considered a haploid fungus with a bipolar mating system. In nature, the α mating type is overwhelmingly...