Sylvain Brunet

Phagosomes are competent organelles for antigen cross-presentation (2003)

Mathieu Houde, Sylvie Bertholet, Etienne Gagnon, Sylvain Brunet, Guillaume Goyette, Annie Laplante, ...

Vue sur les mécanismes de contrôle du cholestérol hépatique suite au stress peroxydatif induit par le fer (2000)

Brunet, Sylvain

Vue sur les mécanismes de contrôle du cholestérol hépatique suite au stress peroxydatif induit par le fer (2000)

Brunet, Sylvain

Mechanism of drug-induced torsade de pointes polymorphic ventricular tachycardia (1998)

Brunet, Sylvain

Mechanism of drug-induced torsade de pointes polymorphic ventricular tachycardia (1998)

Brunet, Sylvain.

Torsade de pointes (TdP) is a proarrhythmic side effect of antiarrhythmic drugs that prolong the QT interval. The exact electrophysiologic mechanism of TdP is under intense investigation. To study...

Polymorphic ventricular tachycardias induced by D-sotalol and phenylephrine in canine preparations of atrioventricular block: initiation in the conduction system followed by spatially unstable re-entry (1998)

Derakhchan, Katayoun, Cardinal, René, Brunet, Sylvain, Klug, Didier, Pharand, Chantal, Kus, Teresa, ...

Objective: Polymorphic ventricular tachycardias (PVT) occur spontaneously in canine hearts under the combination of d-sotalol (S), bradycardia and phenylephrine (PE). We investigated the hypotheses...

Mechanism of drug-induced torsade de pointes polymorphic ventricular tachycardia (1998)

Brunet, Sylvain.

Torsade de pointes (TdP) is a proarrhythmic side effect of antiarrhythmic drugs that prolong the QT interval. The exact electrophysiologic mechanism of TdP is under intense investigation. To study...

Mechanism of drug-induced torsade de pointes polymorphic ventricular tachycardia (1998)

Brunet, Sylvain

Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventricles

Brunet, Sylvain, Aimond, Franck, Li, Huilin, Guo, Weinong, Eldstrom, Jodene, Fedida, David, ...

Previous studies have documented the expression of four kinetically distinct voltage-gated K+ (Kv) currents, Ito,f, Ito,s, IK,slow and Iss, in mouse ventricular myocytes and demonstrated that Ito,f...

Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventricles

Brunet, Sylvain, Aimond, Franck, Li, Huilin, Guo, Weinong, Eldstrom, Jodene, Fedida, David, ...

Previous studies have documented the expression of four kinetically distinct voltage-gated K+ (Kv) currents, Ito,f, Ito,s, IK,slow and Iss, in mouse ventricular myocytes and demonstrated that Ito,f...

Cooperative regulation of Cav1.2 channels by intracellular Mg2+, the proximal C-terminal EF-hand, and the distal C-terminal domain

Brunet, Sylvain, Scheuer, Todd, Catterall, William A.

L-type Ca2+ currents conducted by Cav1.2 channels initiate excitation–contraction coupling in cardiac myocytes. Intracellular Mg2+ (Mgi) inhibits the ionic current of Cav1.2 channels. Because Mgi...