Sylvain Egloff

Regulation of Polymerase II Transcription by 7SK snRNA: Two Distinct RNA Elements Direct P-TEFb and HEXIM1 Binding

Egloff, Sylvain, Van Herreweghe, Elodie, Kiss, Tamás

The positive transcription elongation factor b (P-TEFb), a complex of Cdk9 and cyclin T1/T2, stimulates transcription by phosphorylating RNA polymerase II. The 7SK small nuclear RNA, in cooperation...

Regulation of Polymerase II Transcription by 7SK snRNA: Two Distinct RNA Elements Direct P-TEFb and HEXIM1 Binding

Egloff, Sylvain, Van Herreweghe, Elodie, Kiss, Tamás

The positive transcription elongation factor b (P-TEFb), a complex of Cdk9 and cyclin T1/T2, stimulates transcription by phosphorylating RNA polymerase II. The 7SK small nuclear RNA, in cooperation...

Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb

Van Herreweghe, Elodie, Egloff, Sylvain, Goiffon, Isabelle, Jády, Beáta E, Froment, Carine, Monsarrat, Bernard, ...

The 7SK small nuclear RNA (snRNA) regulates RNA polymerase II transcription elongation by controlling the protein kinase activity of the positive transcription elongation factor b (P-TEFb). In...