Sylvie Souquere-Besse

Wild-type and central DNA flap defective HIV-1 lentiviral vector genomes: intracellular visualization at ultrastructural resolution levels (2006)

Arhel, Nathalie J, Souquere-Besse, Sylvie, Charneau, Pierre

Abstract HIV-1 and other lentiviruses have the unique ability among retroviruses to efficiently replicate in non-dividing cells as a result of the active nuclear import of their DNA genome across an...

Wild-type and central DNA flap defective HIV-1 lentiviral vector genomes: intracellular visualization at ultrastructural resolution levels

Arhel, Nathalie J, Souquere-Besse, Sylvie, Charneau, Pierre

HIV-1 and other lentiviruses have the unique ability among retroviruses to efficiently replicate in non-dividing cells as a result of the active nuclear import of their DNA genome across an...

Wild-type and central DNA flap defective HIV-1 lentiviral vector genomes: intracellular visualization at ultrastructural resolution levels

Arhel, Nathalie J, Souquere-Besse, Sylvie, Charneau, Pierre

HIV-1 and other lentiviruses have the unique ability among retroviruses to efficiently replicate in non-dividing cells as a result of the active nuclear import of their DNA genome across an...

HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore

Arhel, Nathalie J, Souquere-Besse, Sylvie, Munier, Sandie, Souque, Philippe, Guadagnini, Stéphanie, Rutherford, Sandra, ...

The HIV-1 central DNA Flap acts as a cis-acting determinant of HIV-1 genome nuclear import. Indeed, DNA-Flap re-insertion within lentiviral-derived gene transfer vectors strongly stimulates gene...