Wyatt, J R, Vickers, T A, Roberson, J L, Buckheit, R W, Klimkait, T, DeBaets, E, ...
The phosphorothioate oligonucleotide T2G4T2 was identified as an inhibitor of HIV infection in vitro by combinatorial screening of a library of phosphorothioate oligonucleotides that contained all...
Inhibition of NF-kappa B specific transcriptional activation by PNA strand invasion.
Vickers, T A, Griffith, M C, Ramasamy, K, Risen, L M, Freier, S M
Peptide nucleic acid (PNA) strand invasion offers an attractive alternative to DNA oligonucleotide directed triplex formation as a potential tool for gene inhibition. Peptide nucleic acid has been...
Rational screening of oligonucleotide combinatorial libraries for drug discovery.
Ecker, D J, Vickers, T A, Hanecak, R, Driver, V, Anderson, K
Combinatorial strategies offer the potential to generate and screen extremely large numbers of compounds and to identify individual molecules with a desired binding specificity or pharmacological...
Enhancement of ribosomal frameshifting by oligonucleotides targeted to the HIV gag-pol region.
The pol gene of all retroviruses is expressed as a gag-pol fusion protein which is proteolytically processed to produce all viral enzymes. In the human immunodeficiency virus (HIV), the gag and pol...
Wyatt, J R, Vickers, T A, Roberson, J L, Buckheit, R W, Klimkait, T, DeBaets, E, ...
The phosphorothioate oligonucleotide T2G4T2 was identified as an inhibitor of HIV infection in vitro by combinatorial screening of a library of phosphorothioate oligonucleotides that contained all...
Inhibition of NF-kappa B specific transcriptional activation by PNA strand invasion.
Vickers, T A, Griffith, M C, Ramasamy, K, Risen, L M, Freier, S M
Peptide nucleic acid (PNA) strand invasion offers an attractive alternative to DNA oligonucleotide directed triplex formation as a potential tool for gene inhibition. Peptide nucleic acid has been...
Rational screening of oligonucleotide combinatorial libraries for drug discovery.
Ecker, D J, Vickers, T A, Hanecak, R, Driver, V, Anderson, K
Combinatorial strategies offer the potential to generate and screen extremely large numbers of compounds and to identify individual molecules with a desired binding specificity or pharmacological...
Enhancement of ribosomal frameshifting by oligonucleotides targeted to the HIV gag-pol region.
The pol gene of all retroviruses is expressed as a gag-pol fusion protein which is proteolytically processed to produce all viral enzymes. In the human immunodeficiency virus (HIV), the gag and pol...