T. Aikou

Publication List Details

Period

1999 - 2008

Number

18

Co-Authors

Assessment of cervical lymph node metastasis in esophageal carcinoma using ultrasonography.

Natsugoe, S, Yoshinaka, H, Shimada, M, Shirao, K, Nakano, S, Kusano, C, ...

OBJECTIVE: To evaluate the efficacy of ultrasonography for the diagnosis of cervical lymph node metastasis in esophageal carcinoma. SUMMARY BACKGROUND DATA: Ultrasound (US) examination is useful for...

Long-term results of subtotal esophagectomy with three-field lymphadenectomy for carcinoma of the thoracic esophagus.

Baba, M, Aikou, T, Yoshinaka, H, Natsugoe, S, Fukumoto, T, Shimazu, H, ...

OBJECTIVE: This study evaluated the impact of aggressive surgery on survival in patients with carcinoma of the thoracic esophagus. SUMMARY BACKGROUND DATA: Prognostic value of lymph-node status for...

Assessment of cervical lymph node metastasis in esophageal carcinoma using ultrasonography.

Natsugoe, S, Yoshinaka, H, Shimada, M, Shirao, K, Nakano, S, Kusano, C, ...

OBJECTIVE: To evaluate the efficacy of ultrasonography for the diagnosis of cervical lymph node metastasis in esophageal carcinoma. SUMMARY BACKGROUND DATA: Ultrasound (US) examination is useful for...

Long-term results of subtotal esophagectomy with three-field lymphadenectomy for carcinoma of the thoracic esophagus.

Baba, M, Aikou, T, Yoshinaka, H, Natsugoe, S, Fukumoto, T, Shimazu, H, ...

OBJECTIVE: This study evaluated the impact of aggressive surgery on survival in patients with carcinoma of the thoracic esophagus. SUMMARY BACKGROUND DATA: Prognostic value of lymph-node status for...

MUC4 expression is a novel prognostic factor in patients with invasive ductal carcinoma of the pancreas

Saitou, M, Goto, M, Horinouchi, M, Tamada, S, Nagata, K, Hamada, T, ...

Background: Many patients with invasive ductal carcinoma of the pancreas (IDC) have a poor outcome. MUC4 expression has been implicated as a marker for diagnosis and progression of IDC, but there are...

Truncated midkine as a marker of diagnosis and detection of nodal metastases in gastrointestinal carcinomas.

Aridome, K., Takao, S., Kaname, T., Kadomatsu, K., Natsugoe, S., Kijima, F., ...

Midkine (MK) is a growth factor identified as a product of a retinoic acid-responsive gene. A truncated form of MK mRNA, which lacks a sequence encoding the N-terminally located domain, was recently...

Extranodal connective tissue invasion and the expression of desmosomal glycoprotein 1 in squamous cell carcinoma of the oesophagus.

Natsugoe, S., Mueller, J., Kijima, F., Aridome, K., Shimada, M., Shirao, K., ...

We investigated extranodal connective tissue involvement (ECTI) in 39 patients with oesophageal carcinoma. Both the primary tumour and ECTI were immunohistochemically examined using the monoclonal...

Phase-I trial of oral fluoropyrimidine anticancer agent (S-1) with concurrent radiotherapy in patients with unresectable pancreatic cancer

Shinchi, H, Maemura, K, Noma, H, Mataki, Y, Aikou, T, Takao, S

In this phase-I trial, we evaluated the safety of S-1, a novel oral fluoropyrimidine anticancer agent, combined with external-beam radiotherapy (EBRT) to determine the maximum-tolerated dose and...

Clinical significance of midkine expression in pancreatic head carcinoma

Maeda, S, Shinchi, H, Kurahara, H, Mataki, Y, Noma, H, Maemura, K, ...

Midkine (MK) is a heparin-binding growth factor and a product of a retinoic acid-responsive gene. Midkine is overexpressed in many carcinomas and thought to play an important role in carcinogenesis....

Expression of Osteopontin in oesophageal squamous cell carcinoma

Kita, Y, Natsugoe, S, Okumura, H, Matsumoto, M, Uchikado, Y, Setoyama, T, ...

Osteopontin is a multifunctional 34 kDa extracellular matrix protein with a cell-binding domain. It is involved cell adhesion and cell migration and is therefore considered to influence...

Lymphatic invasion using D2-40 monoclonal antibody and its relationship to lymph node micrometastasis in pN0 gastric cancer

Arigami, T, Natsugoe, S, Uenosono, Y, Arima, H, Mataki, Y, Ehi, K, ...

The monoclonal antibody D2-40 is a specific lymphatic endothelial markers and D2-40 staining have been applicable to evaluate lymphatic invasion in various malignant neoplasms. In the present study,...

CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer

Maeda, S, Shinchi, H, Kurahara, H, Mataki, Y, Maemura, K, Sato, M, ...

Although CD133 has been shown to be a marker for cancer stem cells in various tumours, its expression in pancreatic cancer has not yet been clinically reported. In this study, we investigated the...

The predictive value of p53, p53R2, and p21 for the effect of chemoradiation therapy on oesophageal squamous cell carcinoma

Okumura, H, Natsugoe, S, Matsumoto, M, Mataki, Y, Takatori, H, Ishigami, S, ...

The p53 family regulates cell-cycle arrest, triggers apoptosis or is involved in repair of DNA damage. In the present study, we analysed the expression of some p53 family proteins and their responses...

Serum midkine levels are increased in patients with various types of carcinomas

Ikematsu, S, Yano, A, Aridome, K, Kikuchi, M, Kumai, H, Nagano, H, ...

The level of expression of midkine (MK), a heparin-binding growth factor, is increased in many types of human carcinomas. An enzyme-linked immunoassay, which utilizes a combination of rabbit and...