The formation of a deeply-bound $K^- pp$ state with $I=1/2$, $J^\pi=0^-$ by the $^3$He(in-flight $K^-$, $n$) reaction is theoretically investigated in a distorted-wave impulse approximation using the...
Abdelwahab, A., Gardner, M., Parkash, R., Basta, M., Sapp, J., Veltmann, C., ...
Introduction: Scar-related ventricular tachycardia (VT) is often unmappable. Data regarding the outcomes of ablation for mappable vs unmappable VT are lacking. Methods: Catheter ablation of...
Harada, T., Umeya, A., Hirabayashi, Y.
We examine theoretically production of the neutron-rich $^{10}_{\Lambda}$Li hypernucleus by a double-charge exchange ($\pi^-$, $K^+$) reaction on a $^{10}$B target with distorted-wave impulse...
We investigate the structure of the neutron-rich $\Lambda$-hypernucleus $_{\Lambda}^{10}$Li by using microscopic shell-model calculations considering a $\Lambda$-$\Sigma$ coupling effect. The...
The formation of deeply-bound antikaonic $K^-/\bar{K}^0$ nuclear states by nuclear ($K^-$, $N$) reactions is investigated theoretically within a distorted-wave impulse approximation (DWIA),...
Ando, M., Kawamura, Seiji, Nakamura, T., Tsubono, K., Tanaka, T., Funaki, I., ...
DECIGO pathfinder (DPF) is a milestone satellite mission for DECIGO (DECi-hertz Interferometer Gravitational wave Observatory) which is a future space gravitational wave antenna. DECIGO is expected...
The Japanese space gravitational wave antenna: DECIGO (2008)
Kawamura, Seiji, Ando, M., Nakamura, T., Tsubono, K., Tanaka, T., Funaki, I., ...
DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese space gravitational wave antenna. DECIGO is expected to open a new window of observation for gravitational...
The Japanese space gravitational wave antenna - DECIGO (2008)
Kawamura, Seiji, Ando, M., Nakamura, T., Tsubono, K., Tanaka, T., Funaki, I., ...
DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese space gravitational wave antenna. The goal of DECIGO is to detect gravitational waves from various kinds of...
Effects of Quantum Fluctuations in Antisymmetrized Molecular Dynamics (2007)
Hirata Ohnishi, Y. Hirata, A. Ohnishi, Y. Nara, T. Harada, J. Randrup
Introduction Microscopic transport models in nuclear physics have been successfully applied to nuclear reactions. Among them, Antisymmetrized Molecular Dynamics (AMD) 1 takes account both of the...
Reactions Within The Quantum Molecular Dynamics Approach (2007)
Nara Ohnishi, Y. Nara, A. Ohnishi, T. Harada, S. Shinmura
this paper We study the global reaction mechanism.
Quantum Fluctuation Effects on Nuclear and Atomic Cluster Formation (2007)
A. Ohnishi, Jørgen Randrup, Y. Hirata, N. Otuka, Y. Nara, T. Harada
this report, we present the basic idea of the Quantal Langevin model and apply it to various fragmentation processes --- nuclear fragmentation and atomic cluster formation in
Brugger, J., Kulik, A. J., Boero, G., Calame, F., Lee, K., Harada, T., ...
The formation of a deeply-bound $K^-pp$ state by the $^3$He(in-flight $K^-$,$n$) reaction is investigated theoretically in the distorted-wave impulse approximation using the Green's function method....
A CASE STUDY OF BACTERIAL LEAF BLIGHT OF WETLAND RICE (2006)
Cases of bacterial leaf blight of wetland rice and resulting crop damage have been reported from various parts of the country from year to year. With respect to this particular disease, there have...
The Japanese space gravitational wave antenna - DECIGO (2006)
Kawamura, Seiji, Nakamura, T., Ando, M., Seto, N., Tsubono, K., Numata, K., ...
DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese space gravitational wave antenna. It aims at detecting various kinds of gravitational waves between 1 mHz and...
Steen, J. A. J., Hayakawa, J., Harada, T., Lee, K., Calame, F., Boero, G., ...
We have developed a new hybrid AFM probe combining an SU-8 polymer body with a full tungsten cantilever having a nanometric tip. The fabrication is based on surface micromachining a silicon wafer,...
Full tungsten and platinum nanoprobes for electrically conducting scanning probe methods (2006)
Steen, J, Harada, T, Ishii, M, Brugger, J
Recently electrically conducting SPM probes were used as read/write sensor of magneto-resistive nanopillars and ferroelectric domains in the development of >1 Tb/inch2 data storage. Since metal...
Full tungsten and platinum nanoprobes for electrically conducting scanning probe methods (2006)
Steen, J, Harada, T, Ishii, M, Brugger, J
We have developed hybrid AFM probes with SU-8 polymer body and full platinum and tungsten cantilever and tip. The fabrication process uses surface micromachining of a (100) silicon wafer. The metal...
Full platinum nanoprobes for electrically conducting scanning probe methods (2006)
Steen, J, Harada, T, Ishii, M, Brugger, J
Recently electrically conducting SPM probes were used as read/write sensor of magneto-resistive nanopillars and ferroelectric domains in the development of >1 Tb/inch2 data storage. Since metal...
Steen, J, Harada, T, Ishii, M, Brugger, J
Recently electrically conducting SPM probes were used as read/write sensor of magneto-resistive nanopillars and ferroelectric domains in the development of >1 Tb/inch2 data storage. Since metal...
鈴木, 淳史, Harada, T., Hirashima, Y., Suzuki, Atsushi, Goto, M., Kawamura, N., ...
We report the synthesis and some unique properties of polymer gels cross-linked by metal ions. They are made of poly(sodium acrylate) and aluminum ions. Cylindrical and thin plate gels were...
Cruz, RJ, Correia, C, Ribeiro, CMF, Harada, T, Poli De Figueiredo, LF
No abstract available.
Fully tungsten and platinum nanoprobes for electrically conducting scanning probe methods (2005)
Steen, J, Harada, T, Ishii, M, Brugger, J
Recently electrically conducting SPM probes were used as read/write sensor of magneto-resistive nanopillars and ferroelectric domains in the development of >1 Tb/inch2 data storage. Since metal...
ALL TUNGSTEN AFM CANTILEVER WITH < 40 NANOMETRE PYRAMIDAL TIP (2005)
Steen, J, Harada, T, Hayakawa, J, Brugger, J
We develop wear resistant, electrically conducting AFM probes. Here, we describe a new AFM probe made entirely out of tungsten (W). The fabrication involves microfabrication techniques such as...
Optimal Fermi-averaging t-matrix for ($\pi^+$,$K^+$) reactions in $\Lambda$ quasi-free region (2004)
We propose an optimal Fermi-averaging for an elementary $\pi^+$+$n$$\to$$K^+$+$\Lambda$ t-matrix under the on-energy-shell condition, in order to describe ($\pi^+$,$K^+$) reactions on a nuclear...
Microfabricated AFM probe with tungsten cantilever and < 40 nm pyramidal tip (2004)
Steen, J, Harada, T, Brugger, J
In the past, conducting AFM probes have been made by coating standard Si-cantilevers and tips with a thin film of e.g. tungsten (W). Here, we describe a new AFM probe made entirely out of tungsten....
Apoptosis in human endometrium and endometriosis (2004)
Harada, T., Kaponis, A., Iwabe, T., Taniguchi, F., Makrydimas, G., Sofikitis, N., ...
Apoptosis plays a critical role in maintaining tissue homeostasis and represents a normal function to eliminate excess or dysfunctional cells. Accumulated evidence suggests that apoptosis helps to...
Tubal flushing for subfertility (2002)
Watson, A, Lilford, R, Harada, T, Hughes, E
BACKGROUND: A possible therapeutic effect of diagnostic tubal patency testing has been debated in the literature for half a century. Further debate surrounds whether oil-soluble or water-soluble...
Tolman-Bondi collapse in scalar-tensor theories as a probe of gravitational memory (2001)
Harada, T., Goymer, C., Carr, B. J.
In cosmological models with a varying gravitational constant, it is not clear whether primordial black holes preserve the value of $G$ at their formation epoch. We investigate this question by using...
Gravitational Memory ? - a Perturbative Approach (2001)
Harada, T., Carr, B. J., Goymer, C. A.
It has been pointed out that the value of the gravitational ``constant'' in the early universe may be different from that at present. In that case, it was conjectured that primordial black holes may...
The structure of colloidal alloy crystals revealed by ultra-small-angle neutron scattering (2001)
Harada, T, Matsuoka, H, Yamamoto, T, Yamaoka, H, Lin, JS, Agamalian, MM, ...
Birth of timelike naked singularity (2000)
Kudoh, H., Harada, T., Iguchi, H.
We investigate the causal structure of the Harada-Iguchi-Nakao (HIN)'s exact solution in detail, which describes the dynamical formation of naked singularity in the collapse of a regular spherical...
Newtonian Analysis of Gravitational Waves from Naked Singularity (2000)
Nakao, K., Iguchi, H., Harada, T.
Spherical dust collapse generally forms a shell focusing naked singularity at the symmetric center. This naked singularity is massless. Further the Newtonian gravitational potential and speed of the...
Watson, A, Lilford, R, Harada, T, Hughes, E
BACKGROUND: There has been debate in the literature for more than 40 years as to whether flushing of the Fallopian tubes enhances fertility and whether this presumed therapeutic effect is greater...
Harada, T, Matsuoka, H, Ikeda, T, Yamaoka, H, Hamaya, N, Sasaki, S, ...
Torigoe, K, Harada, T, Kusaba, H, Uchiumi, T, Kohno, K, Green, ED, ...
A contig of 21 nonchimeric yeast artificial chromosomes (YACs) was previously assembled across 1.5 Mb of the multidrug resistance (MDR) gene (PGY1 and PGY3) region of human chromosome 7q21.1. This...
Quantum fluctuation effects on hyperfragment formation from Xi^- absorption at rest on 12C (1997)
Hirata, Y., Nara, Y., Ohnishi, A., Harada, T., Randrup, J.
Formation mechanisms of single, twin, and double hypernuclei from Xi^- absorption at rest on 12C are investigated with an refined microscopic transport model, that incorporates the recently developed...
Solid and Cystic Tumor (SCT) of the Pancreas in an Adult Man (1997)
K. Ohiwa, M. Igarashi, N. Nagasue, M. Nagasaki, T. Harada
Solid and cystic tumor (SCT) of the pancreas predominantly Occurs in women, and the occurrence in men is extremely rare. We experienced a male case of SCT. A 38-year-old man was admitted with the...
Furusu, A, Yoshizuka, N, Abe, K, Sasaki, O, Miyazaki, K, Miyazaki, M, ...
K^+ momentum spectrum from (K^-,K^+) reactions in intranuclear cascade model (1996)
Nara, Y., Ohnishi, A., Harada, T., Engel, A.
In a framework of intranuclear cascade (INC) type calculation, we study a momentum spectrum in reactions \KK at a beam momentum of 1.65 GeV/c. INC model calculations are compared with the...
Tanikawa, M., Harada, T., Katagiri, C., Onohara, Y., Yoshida, S., Terakawa, N.
The aim of this study was to investigate the relationship between chlamydia infection and adnexal adhesion. A total of 131 infertile women who were otherwise asymptomatic underwent chlamydia antibody...
Optical Music Recognition Bibliography (1993)
Martin Roth, I. Sonomoto, T. Harada, T. Matsushima, K. Kanamori, M. Konuma, ...
of paper submitted for the International Computer Music Conferecne, 1989. [MM91] W. F. McGee and Paul Merkley. The optical scanning of medievel music. Computers and the Humanities, 25(1):47--53,...
Vliegenthart, J.F.G., Sugahara, K., Ohi, Y., Harada, T., Waard, P. De
Shark cartilage proteoglycans bear predominantly chondroitin 6-sulfate. After exhaustive protease digestion, reductive beta-elimination, and subsequent chondroitinase ABC digestion, 13 hexasaccharide...
Vliegenthart, J.F.G., Waard, P. De, Harada, T., Sugahara, K.
Shark cartilage proteoglycans bear predominantly chondroitin 6-sulfate. After exhaustive protease digestion, reductive beta-elimination and subsequent chondroitinase ABC digestion, 13 hexasaccharide...
Frampton, G., Walker, R. G., Perry, G. J., Harada, T., Cameron, J. S.
Autoantibodies to glomerular components may be pathogenetic in IgA nephropathy. We studied sera from 32 IgA nephropathy patients, 35 normal controls and 102 patient controls with other forms of...
Screw Sense Differentiating Polymerization of Achiral Isocyanides (1984)
Cleij, M.C., Harada, T., Nolte, R.J.M., Drenth, W., Hezemans, A.M.F.
The diagnostic value of laparoscopy on focal hepatic lesions (1982)
HARADA, T., SUGAYA, H., MAEHARA, M.
La laparoscopie a été comparée à d'autres méthodes d'investigation (angiographie abdominale, tomodensitométrie computée, ultrasonographie, etc.) dans le diagnostic de lésions hépatiques...
Present status of mariculture study in Japan for tuna species (1978)
The study of mariculture of tuna species started in 1969 in Japan. There have been two types of trial employed. For this (1) after stripping the eggs from naturally mature adults and artificial...
露地メロンの貯蔵に関する研究 （１） : 特に収穫後の品質に及ぼす貯蔵条件の影響 (1969)
田村, 勉, 中島, 武彦, 今河, 茂, 原田, 隆, TAMURA, T., NAKASHIMA, T., ...
Barba, G., Harper, F., Harada, T., Kohara, M., Goulinet, S., Matsuura, Y., ...
There is now abundant evidence to substantiate an important role of hepatitis C virus (HCV) core protein in cellular gene expression as well as in the viral cycle. Thus the subcellular localization...
Recombinant human bone morphogenetic protein induces bone formation.
Wang, E A, Rosen, V, D'Alessandro, J S, Bauduy, M, Cordes, P, Harada, T, ...
We have purified and characterized active recombinant human bone morphogenetic protein (BMP) 2A. Implantation of the recombinant protein in rats showed that a single BMP can induce bone formation in...
Establishment and Characterization of Cytopathogenic and Noncytopathogenic Pestivirus Replicons
Tautz, N., Harada, T., Kaiser, A., Rinck, G.
Defective interfering particles (DIs) of bovine viral diarrhea virus (BVDV) have been identified and shown to be cytopathogenic (cp) in the presence of noncytopathogenic (noncp) helper virus....
A Cellular J-Domain Protein Modulates Polyprotein Processing and Cytopathogenicity of a Pestivirus
Rinck, G., Birghan, C., Harada, T., Meyers, G., Tautz, N.
Pestiviruses are positive-strand RNA viruses closely related to human hepatitis C virus. Gene expression of these viruses occurs via translation of a polyprotein, which is further processed by...
Regulation of derepressed synthesis of arylsulfatase by tyramine oxidase in Salmonella typhimurium.
The participation of tyramine oxidase in the regulation of arylsulfatase synthesis in Salmonella typhimurium was studied. Arylsulfatase synthesis was repressed by inorganic sulfate, cysteine,...
Murooka, Y, Takizawa, N, Harada, T
The host range of coliphage Mu was greatly expanded to various genera of gram-negative bacteria by using the hybrid plasmic RP4::Mu cts, which is temperature sensitive and which confers resistance to...
Murooka, Y, Higashiura, T, Harada, T
The genes for arylsulfatase (atsA) and tyramine oxidase (tynA) have been mapped in Klebsiella aerogenes by P1 transduction. They are linked to gdhD and trp in the order atsA-tynA-gdhD-trp-pyrF....
Immunological study of the regulation of cellular arylsulfatase synthesis in Klebsiella aerogenes.
Murooka, Y, Yamada, T, Tanabe, S, Harada, T
Regulation of cellular arylsulfatase synthesis in Klebsiella aerogenes was analyzed by immunological techniques. Antibody directed against the purified arylsulfatase from K. aerogenes W70 was...
Yamada, T, Murooka, Y, Harada, T
The arylsulfatases of 21 strains of the family Enterobacteriaceae were compared by measuring their enzymatic activities and immunological reactivities. Enzyme formation under repressing,...
Regulation of tyramine oxidase synthesis in Klebsiella aerogenes.
Okamura, H, Murooka, Y, Harada, T
Tyramine oxidase in Klebsiella aerogenes is highly specific for tyramine, dopamine, octopamine, and norepinephrine, and its synthesis is induced specifically by these compounds. The enzyme is present...
Tyramine oxidase and regulation of arylsulfatase synthesis in Klebsiella aerogenes.
Okamura, H, Murooka, Y, Harada, T
The participation of tyramine oxidase in the regulation of arylsulfatase synthesis in Klebsiella aerogenes was studied. Arylsulfatase was synthesized when this organism was grown with methionine or...
O-alkylhomoserine synthesis catalyzed by O-acetylhomoserine sulfhydrylase in microorganisms.
Murooka, Y, Kakihara, K, Miwa, T, Seto, K, Harada, T
An enzyme that can synthesize O-alkylhomoserine from alcohols and O-acetylhomoserine was purified from Corynebacterium acetophilum. The enzyme was found to be identical to O-acetylhomoserine...
Genetic control of arylsulfatase synthesis in Klebsiella aerogenes.
Murooka, Y, Adachi, T, Okamura, H, Harada, T
It was shown that at least four genes are specifically responsible for arylsulfatase synthesis in Klebsiella aerogenes. Mutations at chromosome site atsA result in enzymatically inactive...
Spontaneous mutation of polysaccharide production in Alcaligenes faecalis var. myxogenes 10C3.
Amemura, A, Hisamatsu, M, Harada, T
Alcaligenes faecalis var. myxogenes 10C3, which produces large amounts of succinoglucan and small amounts of curdlan, was genetically unstable and mutated spontaneously to a form producing more...
Distribution of membrane-bound monoamine oxidase in bacteria.
The distribution of membrane-bound monoamine oxidase in 30 strains of various bacteria was studied. Monoamine oxidase was determined by using an ammonia-selective electrode; analyses were sensitive...
The bacterial host range of coliphage P1 was extented by using the heat-inducible phage P1clr100KM. A gene for kanamycin resistance was transferred from Escherichia coli to members of the family...
Figueroa, J I, Hamilton, A J, Bartholomew, M A, Harada, T, Fenelon, L, Hay, R J
A panel of four murine monoclonal antibodies showing species specificity for the yeast phase of the pathogenic dimorphic fungus Paracoccidioides brasiliensis was produced by using a modification of...
Regulation of arylsulfatase synthesis by sulfur compounds in Klebsiella aerogenes.
Adachi, T, Murooka, Y, Harada, T
In Klebsiella aerogenes, arylsulfatase synthesis was repressed by inorganic sulfate, sulfite, sulfide, thiosulfate, and cysteine, but not by methionine under normal growth conditions. We isolated...
Hiraishi, H, Terano, A, Sugimoto, T, Harada, T, Razandi, M, Ivey, K J
We examined the role of intracellular superoxide dismutase (SOD) as an antioxidant by studying the effect of diethyldithiocarbamate (DDC) on extracellular H2O2-induced damage in cultured rat gastric...
Mutants of Klebsiella aerogenes with three types of mutations affecting regulation of tyramine oxidase were isolated by a simple selection method. In the first type, the mutation (tynP) was closely...
Lithium associated autoimmune thyroiditis.
Shimizu, M, Hirokawa, M, Manabe, T, Shimozuma, K, Sonoo, H, Harada, T
A case of autoimmune thyroiditis after long term treatment with lithium is described in a 29 year old Japanese woman with manic depression. Positive serum antithyroglobulin and antimicrosomal...
Suzuki, N, Harada, T, Mihara, S, Sakane, T
We found previously that cationic anti-DNA autoantibodies (autoAbs) have nephritogenic potential and usage of a specific germline Vk gene, A30, has major influences on cationic charge of the autoAb...
Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor.
Habuchi, H, Suzuki, S, Saito, T, Tamura, T, Harada, T, Yoshida, K, ...
Binding of basic fibroblast growth factor (bFGF) to the extracellular matrix of cultured bovine aorta smooth muscle cells is likely to be mediated via heparan sulphate, since not only exogenous...
Hara, A, Harada, T, Nakagawa, M, Matsuura, K, Nakayama, T, Sawada, H
Dimeric and monomeric proteins containing dihydrodiol dehydrogenase and aldehyde reductase activities were purified from pig lens. The dimeric enzyme of Mr 65,000 specifically oxidized the...
Distribution and characterization of dihydrodiol dehydrogenases in mammalian ocular tissues.
Hara, A, Nakayama, T, Harada, T, Kanazu, T, Shinoda, M, Deyashiki, Y, ...
The immunological relationship of two forms of dihydrodiol dehydrogenase (DD) in pig lens to pig muscle aldose reductase and kidney aldehyde reductase has been studied. Although the minor enzyme...
Is preoperative hepatic arterial chemoembolization safe and effective for hepatocellular carcinoma?
Harada, T, Matsuo, K, Inoue, T, Tamesue, S, Inoue, T, Nakamura, H
OBJECTIVE. The value of preoperative transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) has not been duly appreciated. The authors assessed the advantages and...
Barba, G., Harper, F., Harada, T., Kohara, M., Goulinet, S., Matsuura, Y., ...
There is now abundant evidence to substantiate an important role of hepatitis C virus (HCV) core protein in cellular gene expression as well as in the viral cycle. Thus the subcellular localization...
Recombinant human bone morphogenetic protein induces bone formation.
Wang, E A, Rosen, V, D'Alessandro, J S, Bauduy, M, Cordes, P, Harada, T, ...
We have purified and characterized active recombinant human bone morphogenetic protein (BMP) 2A. Implantation of the recombinant protein in rats showed that a single BMP can induce bone formation in...
Establishment and Characterization of Cytopathogenic and Noncytopathogenic Pestivirus Replicons
Tautz, N., Harada, T., Kaiser, A., Rinck, G.
Defective interfering particles (DIs) of bovine viral diarrhea virus (BVDV) have been identified and shown to be cytopathogenic (cp) in the presence of noncytopathogenic (noncp) helper virus....
A Cellular J-Domain Protein Modulates Polyprotein Processing and Cytopathogenicity of a Pestivirus
Rinck, G., Birghan, C., Harada, T., Meyers, G., Tautz, N.
Pestiviruses are positive-strand RNA viruses closely related to human hepatitis C virus. Gene expression of these viruses occurs via translation of a polyprotein, which is further processed by...
Regulation of derepressed synthesis of arylsulfatase by tyramine oxidase in Salmonella typhimurium.
The participation of tyramine oxidase in the regulation of arylsulfatase synthesis in Salmonella typhimurium was studied. Arylsulfatase synthesis was repressed by inorganic sulfate, cysteine,...
Murooka, Y, Takizawa, N, Harada, T
The host range of coliphage Mu was greatly expanded to various genera of gram-negative bacteria by using the hybrid plasmic RP4::Mu cts, which is temperature sensitive and which confers resistance to...
Murooka, Y, Higashiura, T, Harada, T
The genes for arylsulfatase (atsA) and tyramine oxidase (tynA) have been mapped in Klebsiella aerogenes by P1 transduction. They are linked to gdhD and trp in the order atsA-tynA-gdhD-trp-pyrF....
Immunological study of the regulation of cellular arylsulfatase synthesis in Klebsiella aerogenes.
Murooka, Y, Yamada, T, Tanabe, S, Harada, T
Regulation of cellular arylsulfatase synthesis in Klebsiella aerogenes was analyzed by immunological techniques. Antibody directed against the purified arylsulfatase from K. aerogenes W70 was...
Yamada, T, Murooka, Y, Harada, T
The arylsulfatases of 21 strains of the family Enterobacteriaceae were compared by measuring their enzymatic activities and immunological reactivities. Enzyme formation under repressing,...
Regulation of tyramine oxidase synthesis in Klebsiella aerogenes.
Okamura, H, Murooka, Y, Harada, T
Tyramine oxidase in Klebsiella aerogenes is highly specific for tyramine, dopamine, octopamine, and norepinephrine, and its synthesis is induced specifically by these compounds. The enzyme is present...
Tyramine oxidase and regulation of arylsulfatase synthesis in Klebsiella aerogenes.
Okamura, H, Murooka, Y, Harada, T
The participation of tyramine oxidase in the regulation of arylsulfatase synthesis in Klebsiella aerogenes was studied. Arylsulfatase was synthesized when this organism was grown with methionine or...
O-alkylhomoserine synthesis catalyzed by O-acetylhomoserine sulfhydrylase in microorganisms.
Murooka, Y, Kakihara, K, Miwa, T, Seto, K, Harada, T
An enzyme that can synthesize O-alkylhomoserine from alcohols and O-acetylhomoserine was purified from Corynebacterium acetophilum. The enzyme was found to be identical to O-acetylhomoserine...
Genetic control of arylsulfatase synthesis in Klebsiella aerogenes.
Murooka, Y, Adachi, T, Okamura, H, Harada, T
It was shown that at least four genes are specifically responsible for arylsulfatase synthesis in Klebsiella aerogenes. Mutations at chromosome site atsA result in enzymatically inactive...
Spontaneous mutation of polysaccharide production in Alcaligenes faecalis var. myxogenes 10C3.
Amemura, A, Hisamatsu, M, Harada, T
Alcaligenes faecalis var. myxogenes 10C3, which produces large amounts of succinoglucan and small amounts of curdlan, was genetically unstable and mutated spontaneously to a form producing more...
Distribution of membrane-bound monoamine oxidase in bacteria.
The distribution of membrane-bound monoamine oxidase in 30 strains of various bacteria was studied. Monoamine oxidase was determined by using an ammonia-selective electrode; analyses were sensitive...
The bacterial host range of coliphage P1 was extented by using the heat-inducible phage P1clr100KM. A gene for kanamycin resistance was transferred from Escherichia coli to members of the family...
Figueroa, J I, Hamilton, A J, Bartholomew, M A, Harada, T, Fenelon, L, Hay, R J
A panel of four murine monoclonal antibodies showing species specificity for the yeast phase of the pathogenic dimorphic fungus Paracoccidioides brasiliensis was produced by using a modification of...
Regulation of arylsulfatase synthesis by sulfur compounds in Klebsiella aerogenes.
Adachi, T, Murooka, Y, Harada, T
In Klebsiella aerogenes, arylsulfatase synthesis was repressed by inorganic sulfate, sulfite, sulfide, thiosulfate, and cysteine, but not by methionine under normal growth conditions. We isolated...
Hiraishi, H, Terano, A, Sugimoto, T, Harada, T, Razandi, M, Ivey, K J
We examined the role of intracellular superoxide dismutase (SOD) as an antioxidant by studying the effect of diethyldithiocarbamate (DDC) on extracellular H2O2-induced damage in cultured rat gastric...
Mutants of Klebsiella aerogenes with three types of mutations affecting regulation of tyramine oxidase were isolated by a simple selection method. In the first type, the mutation (tynP) was closely...
Lithium associated autoimmune thyroiditis.
Shimizu, M, Hirokawa, M, Manabe, T, Shimozuma, K, Sonoo, H, Harada, T
A case of autoimmune thyroiditis after long term treatment with lithium is described in a 29 year old Japanese woman with manic depression. Positive serum antithyroglobulin and antimicrosomal...
Suzuki, N, Harada, T, Mihara, S, Sakane, T
We found previously that cationic anti-DNA autoantibodies (autoAbs) have nephritogenic potential and usage of a specific germline Vk gene, A30, has major influences on cationic charge of the autoAb...
Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor.
Habuchi, H, Suzuki, S, Saito, T, Tamura, T, Harada, T, Yoshida, K, ...
Binding of basic fibroblast growth factor (bFGF) to the extracellular matrix of cultured bovine aorta smooth muscle cells is likely to be mediated via heparan sulphate, since not only exogenous...
Hara, A, Harada, T, Nakagawa, M, Matsuura, K, Nakayama, T, Sawada, H
Dimeric and monomeric proteins containing dihydrodiol dehydrogenase and aldehyde reductase activities were purified from pig lens. The dimeric enzyme of Mr 65,000 specifically oxidized the...
Distribution and characterization of dihydrodiol dehydrogenases in mammalian ocular tissues.
Hara, A, Nakayama, T, Harada, T, Kanazu, T, Shinoda, M, Deyashiki, Y, ...
The immunological relationship of two forms of dihydrodiol dehydrogenase (DD) in pig lens to pig muscle aldose reductase and kidney aldehyde reductase has been studied. Although the minor enzyme...
Is preoperative hepatic arterial chemoembolization safe and effective for hepatocellular carcinoma?
Harada, T, Matsuo, K, Inoue, T, Tamesue, S, Inoue, T, Nakamura, H
OBJECTIVE. The value of preoperative transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) has not been duly appreciated. The authors assessed the advantages and...
Torii, I, Morikawa, S, Harada, T, Kitamura, Y
Using mast cell-deficient mutant W/Wv mice and their normal counterpart we re-evaluated the significance of participation of mast cells in allergic inflammatory response. W/Wv mice developed...
Binding ability of complement receptor CR1 to C3 bound on the surface of M+ group A streptococci.
Hong, K, Harada, T, Nishimura, T, Inoue, K
A previous study demonstrated that although M+ bacteria bound C3, mainly C3b and iC3b, via the classical pathway of complement activation, they were not phagocytosed by polymorphonuclear leucocytes...
Intraglomerular C3 synthesis in rats with passive Heymann nephritis.
Sasaki, O., Zhou, W., Miyazaki, M., Abe, K., Koji, T., Verroust, P., ...
Passive Heymann nephritis (PHN), a model of human membranous nephropathy, is an immune-complex-mediated glomerulonephritis characterized by the presence of complement-dependent tissue injury. Recent...
Optic neuropathy associated with hypertrophic cranial pachymeningitis.
Harada, T., Ohashi, T., Ohki, K., Kato, H., Takamura, M., Yoshida, K., ...
Kase, S, Aoki, K, Harada, T, Harada, C, Ohgami, K, Shiratori, K, ...
Aim: To examine the expression of p65, one of nuclear factor-kappa B (NF-κB), in the conjunctival epithelium of the C57Bl6 mouse and a patient with epidemic keratoconjunctivitis (EKC).
Charge distribution of plasma IgA in IgA nephropathy.
Harada, T, Hobby, P, Courteau, M, Knight, J F, Williams, D G
The spectrotype of plasma IgA in patients with IgA nephropathy was studied by isoelectric focussing. Densitometry of the gels showed a significant increase in the anionic region at isoelectric points...
Nose, O, Iida, Y, Kai, H, Harada, T, Ogawa, M, Yabuuchi, H
The breath hydrogen test (BHT) was adapted for use in young infants and children. The diagnostic criterion of sugar malabsorption in the BHT was determined by oral administration of 0.5 g/kg of...
Transient infantile hyperthyrotropinaemia. Report of a case.
Miyai, K, Amino, N, Nishi, K, Fujie, T, Nakatani, K, Nose, O, ...
A case of transient hyperthyrotropinaemia was found by mass screening for neonatal hypothyroidism using the paired TSH assay method. The patient was a baby boy born at term after a normal pregnancy...
Transient infantile hyperthyrotrophinaemia.
Miki, K, Nose, O, Miyai, K, Yabuuchi, H, Harada, T
Sixteen cases of transient infantile hyperthyrotrophinaemia were followed up for two to seven years. Concentrations of serum triiodothyronine, thyroxine, and free thyroxine were maintained within the...
Iwao, M, Fukada, S, Harada, T, Tsujikawa, K, Yagita, H, Hiramine, C, ...
The laminin α2-chain is a component of merosin, a member of the laminin family molecules, which is mainly expressed in the basement membranes of striated muscle. It is known that laminin α2 gene...
Solid and Cystic Tumor (SCT) of the Pancreas in an Adult Man
Ohiwa, K., Igarashi, M., Nagasue, N., Nagasaki, M., Harada, T.
Solid and cystic tumor (SCT) of the pancreas predominantly Occurs in women, and the occurrence in men is extremely rare. We experienced a male case of SCT. A 38-year-old man was admitted with the...
P. Siffalovic, L. Chitu, E. Majkova, M. Jergel, ...
Talk
E. Majkova, P. Siffalovic, L. Chitu, M. Jergel, ...
Talk
Ishigami, S. I., Arii, S., Furutani, M., Niwano, M., Harada, T., Mizumoto, M., ...
Vascular endothelial growth factor (VEGF) may affect the phenotype of cancer cells, such as growth velocity and metastatic potential, due to its probable multifunctional property including a...
Harada, T, Baril, P, Gangeswaran, R, Kelly, G, Chelala, C, Bhakta, V, ...
Pancreatic ductal adenocarcinoma (PDAC) is characterised pathologically by a marked desmoplastic stromal reaction that significantly reduces the sensitivity and specificity of cytogenetic analysis....