T. Hayakawa

Publication List Details

Period

1994 - 2009

Number

125

Co-Authors

Volunteerism in the Inner City: an anthropology of giving (2009)

Hayakawa, T.

This thesis presents an ethnographic account of British volunteering. While volunteering has been researched from multiple disciplinary perspectives, few studies are concerned with the in-depth...

Expected Performance of the ATLAS Experiment - Detector, Trigger and Physics (2008)

Abat, E., Abbott, B., Abdallah, J., Abdelalim, A. A., Abdesselam, A., ...

A detailed study is presented of the expected performance of the ATLAS detector. The reconstruction of tracks, leptons, photons, missing energy and jets is investigated, together with the performance...

One-quasiparticle bands in neutron-rich 187W (2008)

Shizuma, T., Ishii, T., Makii, H., Hayakawa, T., Matsuda, M., Shigematsu, S., ...

Modest spin states in neutron-rich 187W have been populated by using a 186W(18O,17O) one-neutron transfer reaction. Negative-parity bands previously known are extended to higher spin, and two...

Methane Emission Peak observed at Predawn in Tropical Paddy Field:A Case Study of Hainan Island, China (2008)

Yang, Z, Hayakawa, T, Inoue, N

Proceedings of Shinshu University International Symposium 2007 “Sustainable Agriculture and Environment:Asian Network”

One-Quasiparticle Bands in Neutron-Rich W-187 (2008)

Shizuma, T, Ishii, T, Makii, H, Hayakawa, T, Matsuda, M, Shigematsu, S, ...

Modest spin states in neutron-rich W-187 have been populated by using a W-186(O-18,O-17) one-neutron transfer reaction. Negative-parity bands previously known are extended to higher spin, and two...

Mass Spectrometric Study of Collision Interactions of Fast Charged Particles with Water and NaCl Solutions (2008)

Kaneda, M., Shimizu, M., Hayakawa, T., Nishimura, A., Iriki, Y., Tsuchida, H., ...

A new experimental technique has been developed for the investigation of secondary particle emission from liquid targets resulting from collision interactions with fast charged particles. Secondary...

Mass Spectrometric Study of Collision Interactions of Fast Charged Particles with Water and NaCl Solutions (2008)

Kaneda, M., Shimizu, M., Hayakawa, T., Nishimura, A., Iriki, Y., Tsuchida, H., ...

A new experimental technique has been developed for the investigation of secondary particle emission from liquid targets resulting from collision interactions with fast charged particles. Secondary...

Criteria for fitting MEG dipoles with fMRI position constraints (2007)

N. Fujimaki, T. Hayakawa, M. Nielsen, S. Miyauchi

Since MEG and EEG inverse problems are "illposed" (i.e., solutions cannot be uniquely determined), additional information such as fMRI and PET activation data can be used to impose

Visual search processing assessed by MEG (2007)

T. Hayakawa, S. Miyauchi, N. Fujimaki, M. Kato, A. Yagi

Visual search tasks include two different types of search processing. In one type, a target item is segregated automatically from among the distracters without attentional shifts (pop-out); this

MEG Latency Difference Measurement for Priming Experiments (2006)

A Matani, T Hayakawa, S Munetsuna, N Fujimaki

Latency analysis of magnetoencephalography (MEG) for priming experiments, not in motor readiness level but in cognition level, may be useful for identification of the brain system. We performed a...

MEG Latency Difference Measurement for Priming Experiments (2006)

A Matani, T Hayakawa, S Munetsuna, N Fujimaki

Latency analysis of magnetoencephalography (MEG) for priming experiments, not in motor readiness level but in cognition level, may be useful for identification of the brain system. We performed a...

MEG Latency Difference Measurement for Priming Experiments (2006)

A Matani, T Hayakawa, S Munetsuna, N Fujimaki

Latency analysis of magnetoencephalography (MEG) for priming experiments, not in motor readiness level but in cognition level, may be useful for identification of the brain system. We performed a...

MEG Latency Difference Measurement for Priming Experiments (2006)

A Matani, T Hayakawa, S Munetsuna, N Fujimaki

Latency analysis of magnetoencephalography (MEG) for priming experiments, not in motor readiness level but in cognition level, may be useful for identification of the brain system. We performed a...

Photo-disintegration cross section measurements on $^{186}$W, $^{187}$Re and $^{188}$Os: Implications for the Re-Os cosmochronology (2005)

Shizuma, T., Utsunomiya, H., Mohr, P., Hayakawa, T., Goko, S., Makinaga, A., ...

Cross sections of the $^{186}$W, $^{187}$Re, $^{188}$Os($\gamma,n$) reactions were measured using quasi-monochromatic photon beams from laser Compton scattering (LCS) with average energies from 7.3...

New s-process path and its implication to 187Re-187Os nucleo-cosmochronometer (2005)

Hayakawa, T., Shizuma, T., Kajino, T., Chiba, S., Shinohara, N., Nakagawa, T., ...

We study a new s-process path through an isomer of $^{186}$Re to improve a $^{187}$Re-$^{187}$Os nucleo-cosmochronometer. The nucleus $^{187}$Re is produced by this new path of...

$\Sigma^+$p elastic scattering cross sections in the region of 350$\leq P\Sigma^+\leq 750 MeV/c$ with a scintillating fiber active target (2005)

Ahn, J.K., Akikawa, H., Arvieux, J., Bassalleck, B., Chung, M.S., En'Yo, H., ...

A hyperon–nucleon scattering experiment, KEK-PS E289, was carried out at the K2 beam line in KEK. We adopted a scintillating fiber active target as a hydrogen target for hyperon production and...

$\Sigma^+$p elastic scattering cross sections in the region of 350$\leq P\Sigma^+\leq 750 MeV/c$ with a scintillating fiber active target (2005)

Ahn, J.K., Akikawa, H., Arvieux, J., Bassalleck, B., Chung, M.S., En'Yo, H., ...

A hyperon–nucleon scattering experiment, KEK-PS E289, was carried out at the K2 beam line in KEK. We adopted a scintillating fiber active target as a hydrogen target for hyperon production and...

Accumulation and toxicity of monophenyl arsenicals in rat endothelial cells (2005)

Hirano, S., Kobayashi, Y., Hayakawa, T., Cui, X., Yamamoto, M., Kanno, S., ...

Clark 1 (diphenylarsine chloride) and Clark 2 ( diphenylarsine cyanide) were used as chemical weapon agents (CWA), and the soil contamination by these CWA and their degraded products, diphenyl and...

Accumulation and toxicity of monophenyl arsenicals in rat endothelial cells (2005)

Hirano, S., Kobayashi, Y., Hayakawa, T., Cui, X., Yamamoto, M., Kanno, S., ...

Clark 1 (diphenylarsine chloride) and Clark 2 ( diphenylarsine cyanide) were used as chemical weapon agents (CWA), and the soil contamination by these CWA and their degraded products, diphenyl and...

s-process branching at 185W revised (2004)

Mohr, P., Shizuma, T., Ueda, H., Goko, S., Makinaga, A., Hara, K. Y., ...

The neutron capture cross section of the unstable s-process branching nucleus 185W has been derived from experimental data of the inverse 186W(g,n)185W photodisintegration taken with monochromatic...

Evidence for nucleosynthesis in supernova $\gamma$-process: Universal scaling on p-nuclei (2004)

Hayakawa, T., Iwamoto, N., Shizuma, T., Kajino, T., Umeda, H., Nomoto, K.

With analyzing the solar system abundance, we have found two universal scaling laws concerning the p- and s-nuclei. They indicate that the gamma-process in supernova (SN) explosions is the most...

Subchronic Exposure to Arsenic Through Drinking Water Alters Expression of Cancer-Related Genes in Rat Liver (2004)

Cui, X., Li, S., Shraim, A., Kobayashi, Y., Hayakawa, T., Kanno, S., ...

Although arsenic exposure causes liver disease and/or hepatoma, little is known about molecular mechanisms of arsenic-induced liver toxicity or carcinogenesis. We investigated the effects of arsenic...

An fMRI-constrained MEG source analysis with procedures for dividing and grouping activation (2002)

Fujimaki,N., Hayakawa,T., Nielsen,M., Knösche,T. R., Miyauchi,S.

To analyze neural activity using magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI), we developed a method for fixing equivalent current dipoles of MEG in activation areas...

An fMRI-constrained MEG source analysis with procedures for dividing and grouping activation (2002)

Fujimaki,N., Hayakawa,T., Nielsen,M., Knösche,T. R., Miyauchi,S.

To analyze neural activity using magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI), we developed a method for fixing equivalent current dipoles of MEG in activation areas...

High-K negative parity states in 184Os (2002)

Shizuma, T., Stevenson, P. D., Walker, P. M., Toh, Y., Hayakawa, T., Oshima, M., ...

High-spin states in 184Os have been studied using the 170Er(18O,4n) reaction at a beam energy of 85 MeV. Several new negative parity levels including a 48-ns Kpi = (18-) isomer have been identified....

An fMRI-constrained MEG source analysis with procedures for dividing and grouping activation (2002)

Fujimaki, N., Hayakawa, T., Nielsen, M., Knösche, T. R., Miyauchi, S.

To analyze neural activity using magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI), we developed a method for fixing equivalent current dipoles of MEG in activation areas...

Inactivation of CMP-N-acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution (2002)

Chou, H. H., Hayakawa, T., Diaz, S., Krings, M., Indriati, E., Leakey, M., ...

Humans are genetically deficient in the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc) because of an Alu- mediated inactivating mutation of the gene encoding the enzyme...

Constraints on neutrino oscillation parameters from the measurement of day-night solar neutrino fluxes at Super-Kamiokande (1998)

Hayakawa, T., Ichihara, E., Inoue, K.

A search for day-night variations in the solar neutrino flux resulting from neutrino oscillations has been carried out using the 504 day sample of solar neutrino data obtained at Super-Kamiokande....

Plasticity of Fe2(Dy,Tb) Magnetostrictive Compound at High Temperature. (1998)

Saka, H., Hayakawa, T., Maruyama, K., Nakamura, M., Mizutani, H.

Single crystals of Fe2(Dy,Tb) deformed between 800 and 950 C in compression were brittle below 800 C, very ductile above 875 C, and deformed as much as 20% at 950 C.

An animal study on the bone behaviour of Ca-P-coated implants: influence of implant location (1997)

Hayakawa, T, Van Der Waerden, J P, Wolke, J G, Jansen, J A

Four different implant materials were installed into the mandibular corner of goats to investigate the trabecular bone response in a mainly unloaded model. The implants were installed using a...

High spin states in 158 Dy

Hayakawa, T., Toh, Y., Oshima, M., Matsuda, M., Hatsukawa, Y., Shizuma, J., ...

High spin states in 158Dy have been investigated using in-beam -ray spectroscopy techniques with the 150Nd(12C,4n) reaction. Six rotational bands and several interband transitions have been observed....

High spin states in 158 Dy

Hayakawa, T., Toh, Y., Oshima, M., Matsuda, M., Hatsukawa, Y., Shizuma, J., ...

High spin states in 158Dy have been investigated using in-beam -ray spectroscopy techniques with the 150Nd(12C,4n) reaction. Six rotational bands and several interband transitions have been observed....

Genetically engineered rice resistant to rice stripe virus, an insect-transmitted virus.

Hayakawa, T, Zhu, Y, Itoh, K, Kimura, Y, Izawa, T, Shimamoto, K, ...

The coat protein (CP) gene of rice stripe virus was introduced into two japonica varieties of rice by electroporation of protoplasts. The resultant transgenic plants expressed the CP at high levels...

Purification and Characterization of Membrane-Bound Inositol Phospholipid-Specific Phospholipase C from Suspension-Cultured Rice (Oryza sativa L.) Cells (Identification of a Regulatory Factor).

Yotsushima, K., Mitsui, T., Takaoka, T., Hayakawa, T., Igaue, I.

A membrane-bound inositol phospholipid-specific phospholipase C was solubilized from rice (Oryza sativa L.) microsomal membranes and purified to apparent homogeneity using a series of chromatographic...

Light-regulated and cell-specific expression of tomato rbcS-gusA and rice rbcS-gusA fusion genes in transgenic rice.

Kyozuka, J, McElroy, D, Hayakawa, T, Xie, Y, Wu, R, Shimamoto, K

A previously isolated rice (Oryza sativa) rbcS gene was further characterized. This analysis revealed specific sequences in the 5' regulatory region of the rice rbcS gene that are conserved in rbcS...

Changes in the Content of Two Glutamate Synthase Proteins in Spikelets of Rice (Oryza sativa) Plants during Ripening.

Hayakawa, T., Yamaya, T., Mae, T., Ojima, K.

Nitrogen accumulation in the apical spikelets on the primary branches of the main stem of rice plants have been studied during the ripening process (0-35 d after flowering). The level of...

Effect of ursodeoxycholate on the biliary excretion of cefotiam and sulbenicillin in patients with percutaneous transhepatic biliary drainage.

Higashi, K, Hayakawa, T, Katagiri, K, Tsukada, K, Ito, K, Hoshino, M, ...

The effects of ursodeoxycholate administration on the biliary excretion of the antibiotics cefotiam and sulbenicillin were studied in five patients with stable hepatic function receiving percutaneous...

The secretion leader of Mucor pusillus rennin which possesses an artificial Lys-Arg sequence directs the secretion of mature human growth hormone by Saccharomyces cerevisiae.

Hiramatsu, R, Horinouchi, S, Uchida, E, Hayakawa, T, Beppu, T

The prepro-peptide of fungal aspartic proteinase, Mucor pusillus rennin, is useful as a secretion leader for efficient secretion of human growth hormone (HGH) from Saccharomyces cerevisiae. For...

Primary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation system.

Suzuki, M, Hayakawa, T, Shaw, J P, Rekik, M, Harayama, S

Xylene monooxygenase, encoded by the TOL plasmid of Pseudomonas putida, catalyzes the oxidation of toluene and xylenes and consists of two different subunits encoded by xylA and xylM. In this study,...

Synthesis of decadeoxyribonucleotides containing 5-modified uracils and their interactions with restriction endonucleases Bgl II, Sau 3AI and Mbo I (nucleosides and nucleotides 82).

Hayakawa, T, Ono, A, Ueda, T

Decadeoxyribonucleotides containing uracil, 5-bromouracil, 5-cyanouracil and 5-ethyluracil in recognition sequences of restriction endonucleases Bgl II, Sau 3AI, Mbo I were synthesized....

Accumulation of allelic losses on chromosome 10 in human gliomas at recurrence

Tokiyoshi, K, Yoshimine, T, Maruno, M, Hayakawa, T

Aims—To elucidate the implications of allelic loss on chromosome 10 in the malignant progression of human gliomas.

Neural cell adhesion molecule L1 in gliomas: correlation with TGF-beta and p53.

Tsuzuki, T, Izumoto, S, Ohnishi, T, Hiraga, S, Arita, N, Hayakawa, T

AIMS: To assess immunohistochemically whether the neural cell adhesion molecule L1, which is a member of the immunoglobulin superfamily and has been shown recently to be a stimulating factor for...

Microtubule-independent choleresis and anti-cholestatic action of tauroursodeoxycholate in colchicine-treated rat liver.

Nakai, T, Katagiri, K, Hoshino, M, Hayakawa, T, Ohiwa, T

In order to cast light on the anti-cholestatic and cytoprotective properties of ursodeoxycholic acid (UDCA), intrahepatic transport and secretion of bile salts and biliary phospholipids were...

Comparative studies on bile flow and biliary lipid excretion after bile-acid loading in normal and partially hepatectomized rats.

Hoshino, M, Hirano, A, Hayakawa, T, Kamiya, Y, Ohiwa, T, Tanaka, A, ...

This study was performed to investigate sequential changes in bile secretion and biliary lipids after taurocholic acid (TCA) loading of regenerating rat liver. TCA was administered intravenously at...

Hormonal regulation of collagenolysis in uterine cervical fibroblasts. Modulation of synthesis of procollagenase, prostromelysin and tissue inhibitor of metalloproteinases (TIMP) by progesterone and oestradiol-17 beta.

Sato, T, Ito, A, Mori, Y, Yamashita, K, Hayakawa, T, Nagase, H

Rabbit uterine cervical fibroblasts produced a large amount of matrix metalloproteinases (MMPs) such as collagenase (MMP-1) and stromelysin (MMP-3) and a small relatively amount of tissue inhibitor...

Interaction between tissue inhibitor of metalloproteinases-2 and progelatinase A: immunoreactivity analyses.

Fujimoto, N, Ward, R V, Shinya, T, Iwata, K, Yamashita, K, Hayakawa, T

By immunoreactivity analysis using monoclonal antibodies, we showed that the C-terminal domain [R415-631; R is residue] of progelatinase A [pro-matrix metalloproteinase-2 (proMMP-2); EC 3.4.24.24]...

Spatiotemporal relationships among early events of fertilization in sea urchin eggs revealed by multiview microscopy.

Suzuki, K, Tanaka, Y, Nakajima, Y, Hirano, K, Itoh, H, Miyata, H, ...

Four early events of egg fertilization, changes in intracellular calcium concentration and intracellular pH, reorientation of the surface membrane, and the elevation of the fertilization envelope,...

Genetically engineered rice resistant to rice stripe virus, an insect-transmitted virus.

Hayakawa, T, Zhu, Y, Itoh, K, Kimura, Y, Izawa, T, Shimamoto, K, ...

The coat protein (CP) gene of rice stripe virus was introduced into two japonica varieties of rice by electroporation of protoplasts. The resultant transgenic plants expressed the CP at high levels...

Purification and Characterization of Membrane-Bound Inositol Phospholipid-Specific Phospholipase C from Suspension-Cultured Rice (Oryza sativa L.) Cells (Identification of a Regulatory Factor).

Yotsushima, K., Mitsui, T., Takaoka, T., Hayakawa, T., Igaue, I.

A membrane-bound inositol phospholipid-specific phospholipase C was solubilized from rice (Oryza sativa L.) microsomal membranes and purified to apparent homogeneity using a series of chromatographic...

Light-regulated and cell-specific expression of tomato rbcS-gusA and rice rbcS-gusA fusion genes in transgenic rice.

Kyozuka, J, McElroy, D, Hayakawa, T, Xie, Y, Wu, R, Shimamoto, K

A previously isolated rice (Oryza sativa) rbcS gene was further characterized. This analysis revealed specific sequences in the 5' regulatory region of the rice rbcS gene that are conserved in rbcS...

Changes in the Content of Two Glutamate Synthase Proteins in Spikelets of Rice (Oryza sativa) Plants during Ripening.

Hayakawa, T., Yamaya, T., Mae, T., Ojima, K.

Nitrogen accumulation in the apical spikelets on the primary branches of the main stem of rice plants have been studied during the ripening process (0-35 d after flowering). The level of...

Effect of ursodeoxycholate on the biliary excretion of cefotiam and sulbenicillin in patients with percutaneous transhepatic biliary drainage.

Higashi, K, Hayakawa, T, Katagiri, K, Tsukada, K, Ito, K, Hoshino, M, ...

The effects of ursodeoxycholate administration on the biliary excretion of the antibiotics cefotiam and sulbenicillin were studied in five patients with stable hepatic function receiving percutaneous...

The secretion leader of Mucor pusillus rennin which possesses an artificial Lys-Arg sequence directs the secretion of mature human growth hormone by Saccharomyces cerevisiae.

Hiramatsu, R, Horinouchi, S, Uchida, E, Hayakawa, T, Beppu, T

The prepro-peptide of fungal aspartic proteinase, Mucor pusillus rennin, is useful as a secretion leader for efficient secretion of human growth hormone (HGH) from Saccharomyces cerevisiae. For...

Primary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation system.

Suzuki, M, Hayakawa, T, Shaw, J P, Rekik, M, Harayama, S

Xylene monooxygenase, encoded by the TOL plasmid of Pseudomonas putida, catalyzes the oxidation of toluene and xylenes and consists of two different subunits encoded by xylA and xylM. In this study,...

Synthesis of decadeoxyribonucleotides containing 5-modified uracils and their interactions with restriction endonucleases Bgl II, Sau 3AI and Mbo I (nucleosides and nucleotides 82).

Hayakawa, T, Ono, A, Ueda, T

Decadeoxyribonucleotides containing uracil, 5-bromouracil, 5-cyanouracil and 5-ethyluracil in recognition sequences of restriction endonucleases Bgl II, Sau 3AI, Mbo I were synthesized....

Accumulation of allelic losses on chromosome 10 in human gliomas at recurrence

Tokiyoshi, K, Yoshimine, T, Maruno, M, Hayakawa, T

Aims—To elucidate the implications of allelic loss on chromosome 10 in the malignant progression of human gliomas.

Neural cell adhesion molecule L1 in gliomas: correlation with TGF-beta and p53.

Tsuzuki, T, Izumoto, S, Ohnishi, T, Hiraga, S, Arita, N, Hayakawa, T

AIMS: To assess immunohistochemically whether the neural cell adhesion molecule L1, which is a member of the immunoglobulin superfamily and has been shown recently to be a stimulating factor for...

Microtubule-independent choleresis and anti-cholestatic action of tauroursodeoxycholate in colchicine-treated rat liver.

Nakai, T, Katagiri, K, Hoshino, M, Hayakawa, T, Ohiwa, T

In order to cast light on the anti-cholestatic and cytoprotective properties of ursodeoxycholic acid (UDCA), intrahepatic transport and secretion of bile salts and biliary phospholipids were...

Comparative studies on bile flow and biliary lipid excretion after bile-acid loading in normal and partially hepatectomized rats.

Hoshino, M, Hirano, A, Hayakawa, T, Kamiya, Y, Ohiwa, T, Tanaka, A, ...

This study was performed to investigate sequential changes in bile secretion and biliary lipids after taurocholic acid (TCA) loading of regenerating rat liver. TCA was administered intravenously at...

Hormonal regulation of collagenolysis in uterine cervical fibroblasts. Modulation of synthesis of procollagenase, prostromelysin and tissue inhibitor of metalloproteinases (TIMP) by progesterone and oestradiol-17 beta.

Sato, T, Ito, A, Mori, Y, Yamashita, K, Hayakawa, T, Nagase, H

Rabbit uterine cervical fibroblasts produced a large amount of matrix metalloproteinases (MMPs) such as collagenase (MMP-1) and stromelysin (MMP-3) and a small relatively amount of tissue inhibitor...

Interaction between tissue inhibitor of metalloproteinases-2 and progelatinase A: immunoreactivity analyses.

Fujimoto, N, Ward, R V, Shinya, T, Iwata, K, Yamashita, K, Hayakawa, T

By immunoreactivity analysis using monoclonal antibodies, we showed that the C-terminal domain [R415-631; R is residue] of progelatinase A [pro-matrix metalloproteinase-2 (proMMP-2); EC 3.4.24.24]...

Spatiotemporal relationships among early events of fertilization in sea urchin eggs revealed by multiview microscopy.

Suzuki, K, Tanaka, Y, Nakajima, Y, Hirano, K, Itoh, H, Miyata, H, ...

Four early events of egg fertilization, changes in intracellular calcium concentration and intracellular pH, reorientation of the surface membrane, and the elevation of the fertilization envelope,...

High spin states in 158 Dy

Hayakawa, T., Toh, Y., Oshima, M., Matsuda, M., Hatsukawa, Y., Shizuma, J., ...

High spin states in 158Dy have been investigated using in-beam -ray spectroscopy techniques with the 150Nd(12C,4n) reaction. Six rotational bands and several interband transitions have been observed....

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis

Yoshihara, Y., Nakamura, H., Obata, K., Yamada, H., Hayakawa, T., Fujikawa, K., ...

OBJECTIVE—Matrix metalloproteinases (MMPs) are expressed in joint tissues of patients with rheumatoid arthritis (RA) and osteoarthritis (OA). The objective of this study was to define the steady...

Regulation of tumour necrosis factor (TNF) induced apoptosis by soluble TNF receptors in Helicobacter pylori infection

Shibata, J, Goto, H, Arisawa, T, Niwa, Y, Hayakawa, T, Nakayama, A, ...

BACKGROUND—Tumour necrosis factor (TNF) is a predominant cytokine produced in the gastric mucosa of patients with Helicobacter pylori infection. TNF induces apoptosis in a variety of cells. The...

The utility of endoscopic ultrasonography and endoscopy in the endoscopic mucosal resection of early gastric cancer

Ohashi, S, Segawa, K, Okamura, S, Mitake, M, Urano, H, Shimodaira, M, ...

OBJECTIVE—To clarify the usefulness of endoscopic ultrasonography (EUS) and endoscopy in the endoscopic mucosal resection (EMR) of early gastric cancer. Patients/Methods—EMR was performed in...

Evaluation of prognosis of squamous cell carcinoma of the oesophagus by endoscopic ultrasonography

Shinkai, M, Niwa, Y, Arisawa, T, Ohmiya, N, Goto, H, Hayakawa, T

BACKGROUND/AIMS—For pretherapeutic staging of squamous cell carcinoma of the oesophagus, endoscopic ultrasonography (EUS) is considered the most profitable modality because it can provide cross...

Interferon responsiveness in patients infected with hepatitis C virus 1b differs depending on viral subtype

Nakano, I, Fukuda, Y, Katano, Y, Toyoda, H, Hayashi, K, Hayakawa, T, ...

BACKGROUND—Genotype 1b of hepatitis C virus (HCV) comprises mainly three subtypes, each named for its geographic prevalence (worldwide, W; Japan, J; and not in Japan, NJ).
AIM—To characterise...

Liver dysfunction among workers handling 5-nitro-o-toluidine

Shimizu, H, Kumada, T, Nakano, S, Kiriyama, S, Sone, Y, Honda, T, ...

Background: 5-Nitro-o-toluidine is an aromatic nitro amino compound. While other aromatic compounds are known to damage the human liver and are registered as toxic substances, toxicity information...

Two phenotypically distinct B lymphocytes (IgMhighIgDlow and IgMlowIgDhigh) in chronic gastric ulcer in the rat.

Ohmiya, N, Ito, M, Ohbayashi, M, Arisawa, T, Goto, H, Tsukamoto, Y, ...

We determined the kinetics and phenotypes of infiltrating B cells in gastric ulcer in the rat induced by gastric injection of acetic acid (day 0). Few B cells were found in the lesion in the early...

Naive and memory T cell infiltrates in chronic hepatitis C: phenotypic changes with interferon treatment

IMADA, K, FUKUDA, Y, KOYAMA, Y, NAKANO, I, YAMADA, M, KATANO, Y, ...

The phenotypes of infiltrating lymphocytes in liver with chronic hepatitis C, including changes associated with interferon (IFN) treatment, were characterized. Specimens obtained from 22 patients...

Fluid secretion in interlobular ducts isolated from guinea-pig pancreas

Ishiguro, H, Naruse, S, Steward, M C, Kitagawa, M, Ko, S B H, Hayakawa, T, ...

Pancreatic HCO3− and fluid secretion were studied by monitoring luminal pH (pHL) and luminal volume simultaneously in interlobular duct segments isolated from guinea-pig pancreas. The secretory...

Luminal ATP stimulates fluid and HCO3− secretion in guinea-pig pancreatic duct

Ishiguro, H, Naruse, S, Kitagawa, M, Hayakawa, T, Case, R M, Steward, M C

The location of purinoceptors in the pancreatic duct and their role in regulating ductal secretion have been investigated by applying ATP and UTP to basolateral and luminal surfaces of pancreatic...

CO2 permeability and bicarbonate transport in microperfused interlobular ducts isolated from guinea-pig pancreas

Ishiguro, H, Naruse, S, Kitagawa, M, Suzuki, A, Yamamoto, A, Hayakawa, T, ...

Permeabilities of the luminal and basolateral membranes of pancreatic duct cells to CO2 and HCO3− were examined in interlobular duct segments isolated from guinea-pig pancreas. Intracellular pH...

Chloride transport in microperfused interlobular ducts isolated from guinea-pig pancreas

Ishiguro, H, Naruse, S, Kitagawa, M, Mabuchi, T, Kondo, T, Hayakawa, T, ...

Isolated interlobular ducts from the guinea-pig pancreas secrete a HCO3−-rich fluid in response to secretin. To determine the role of Cl− transporters in this process, intracellular Cl−...

Uptake of bleomycin by human brain tumours 1

Hayakawa, T., Ushio, Y., Morimoto, K., Hasegawa, H., Mogami, H., Horibata, K.

The uptake of bleomycin (BLM) by various types of brain tumours after intravenous or intrathecal administration was investigated by bioassay in 67 patients. The correlation between the BLM...

Response of cerebrospinal fluid pressure to hyperbaric oxygenation1

Hayakawa, T., Kanai, N., Kuroda, R., Yamada, R., Mogami, H.

The response of cerebrospinal fluid pressure (CSFP) to hyperbaric oxygenation (OHP) was investigated in 13 patients with acute cerebral damage and in dogs with or without experimentally produced...

Usefulness of intraoperative cortical blood flow measurement by heat clearance method for monitoring cerebral ischaemia during therapeutic carotid ligation.

Hayakawa, T, Yamada, K, Iwata, Y, Kato, A, Yoshimine, T, Ushio, Y, ...

Changes of regional cortical blood flow (rCBF) was monitored by the heat clearance method during the operation of cervical carotid ligation combined with superficial temporal artery and middle...

Surgical treatment of brain metastases of lung cancer: retrospective analysis of 89 cases.

Nakagawa, H, Miyawaki, Y, Fujita, T, Kubo, S, Tokiyoshi, K, Tsuruzono, K, ...

The records of 89 patients who underwent surgery for solitary or multiple parenchymal brain metastases of lung cancer at the Osaka Center for Adult Diseases between 1978 and 1990 were reviewed with...

Membrane Potential and Bicarbonate Secretion in Isolated Interlobular Ducts from Guinea-pig Pancreas

Ishiguro, H., Steward, M.C., Sohma, Y., Kubota, T., Kitagawa, M., Kondo, T., ...

The interlobular duct cells of the guinea-pig pancreas secrete HCO3− across their luminal membrane into a HCO3−-rich (125 mM) luminal fluid against a sixfold concentration gradient. Since HCO3−...

On tests for the mean direction of the Langevin distribution

T. Hayakawa

Asymptotic expansion, central limit theorem, Langevin distribution, likelihood ratio criterion, Watson statistic, Rao statistic, modified Wald statistic,

Characterisation of a new mouse monoclonal antibody (ONS-M21) reactive with both medulloblastomas and gliomas.

Moriuchi, S., Shimizu, K., Miyao, Y., Hayakawa, T.

We developed an IgG1 mouse monoclonal antibody (ONS-M21) directed against a cell surface antigen of medulloblastomas and gliomas in immunisation of mice with the ONS-76 medulloblastoma cell line. The...

Enhanced effect of reserpine upon growth-inhibitory action of ACNU on ACNU-resistant C6 glioma.

Yoshida, T., Shimizu, K., Ushio, Y., Hayakawa, T., Mogami, H., Sakamoto, Y.

Reserpine was found to enhance the cytotoxicity of ACNU on ACNU-resistant C6 glioma (C6/ACNU) cells in vitro. When reserpine was added along with ACNU to the C6/ACNU cells in vitro. When reserpine...

Intrathecal Chemotherapy: Selection of Cytostatic Agents

Hayakawa, T., Yamada, R., Kanai, N., Kuroda, R., Ushio, Y., Higashi, H., ...

Selection of cytostatic agents for intrathecal administration is the subject of this paper.

Regulation of interferon responses in medulloblastoma cells by interferon regulatory factor-1 and -2.

Park, K. C., Shimizu, K., Hayakawa, T., Tanaka, N.

Transcriptional activator interferon regulatory factor (IRF)-1 and repressor IRF-2 are known to play a critical role in the regulation of interferon (IFN) responses and oncogenesis in fibroblasts....

Monoclonal antibody ONS-M21 recognizes integrin α3 in gliomas and medulloblastomas

Kishima, H, Shimizu, K, Tamura, K, Miyao, Y, Mabuchi, E, Tominaga, E, ...

The monoclonal antibody ONS-M21 recognizes an antigen found on the surface of glioma and medulloblastoma cells but does not react with the antigens of normal brain tissue. We purified and identified...