T. Hirayama

Publication List Details

Period

1996 - 2006

Number

77

Co-Authors

Classical Simulation of Quantum Fields II (2005)

Hirayama, T., Holdom, B., Koniuk, R., Yavin, T.

We consider the classical time evolution of a real scalar field in 2 dimensional Minkowski space with a $\lambda \phi^4$ interaction. We compute the spatial and temporal two-point correlation...

Classical Simulation of Quantum Fields I (2005)

Hirayama, T., Holdom, B.

We study classical field theories in a background field configuration where all modes of the theory are excited, matching the zero-point energy spectrum of quantum field theory. Our construction...

Fluctuations, Ghosts, and the Cosmological Constant (2004)

Hirayama, T., Holdom, B.

For a large region of parameter space involving the cosmological constant and mass parameters, we discuss fluctuating spacetime solutions that are effectively Minkowskian on large time and distance...

Quantitative trait loci analysis of nitrate storage in Arabidopsis leading to an investigation of the contribution of the anion channel gene, AtCLC-c, to variation in nitrate levels (2004)

Harada, H., Kuromori, T., Hirayama, T., Shinozaki, K., Leigh, Roger Allen

Storage of excess nitrate in the vacuole and its subsequent remobilization is an important aspect of a plant’s nitrogen economy, but the genes controlling the underlying processes have not all been...

Quantitative trait loci analysis of nitrate storage in Arabidopsis leading to an investigation of the contribution of the anion channel gene, AtCLC-c, to variation in nitrate levels (2004)

Harada, H., Kuromori, T., Hirayama, T., Shinozaki, K., Leigh, Roger Allen

Storage of excess nitrate in the vacuole and its subsequent remobilization is an important aspect of a plant’s nitrogen economy, but the genes controlling the underlying processes have not all been...

Can black holes have Euclidean cores? (2003)

Hirayama, T., Holdom, B.

The search for regular black hole solutions in classical gravity leads us to consider a core of Euclidean signature in the interior of a black hole. Solutions of Lorentzian and Euclidean general...

Osteoclast formation from circulating precursors in osteoporosis (2003)

Jevon, M, Hirayama, T, Brown, MA, Wass, JAH, Sabokbar, A, Ostelere, S, ...

Objective: An imbalance between bone formation and bone resorption is thought to underlie the pathogenesis of reduced bone mass in osteoporosis. Bone resorption is carried out by osteoclasts, which...

Osteoclast formation from circulating precursors in osteoporosis (2003)

Jevon, M, Hirayama, T, Brown, MA, Wass, JAH, Sabokbar, A, Ostelere, S, ...

Objective: An imbalance between bone formation and bone resorption is thought to underlie the pathogenesis of reduced bone mass in osteoporosis. Bone resorption is carried out by osteoclasts, which...

Motion planning for mobile manipulator with keeping manipulability (2002)

Nagatani, K., Hirayama, T., Gofuku, A., Tanaka, Y.

Our research goal is to realize a motion planning for an intelligent mobile manipulator. To plan a mobile manipulator's motion, it is popular that the base robot motion is regarded as manipulator's...

Osteoclast formation and activity in the pathogenesis of osteoporosis in rheumatoid arthritis (2002)

Hirayama, T., Danks, L., Sabokbar, A., Athanasou, N. A.

Objective. Rheumatoid arthritis (RA) is often complicated by generalized osteopenia due to increased bone resorption by osteoclasts. We analysed a number of cellular and humoral factors that...

Osteoclast formation and activity in the pathogenesis of osteoporosis in rheumatoid arthritis (2002)

Hirayama, T., Danks, L., Sabokbar, A., Athanasou, N. A.

Objective. Rheumatoid arthritis (RA) is often complicated by generalized osteopenia due to increased bone resorption by osteoclasts. We analysed a number of cellular and humoral factors...

Bound and Radiation Fields in the Rindler Frame (2001)

Hirayama, T.

The energy-momentum tensor of the Li\'enard-Wiechert field is split into bound and emitted parts in the Rindler frame, by generalizing the reasoning of Teitelboim applied in the inertial frame. Our...

Structural Phase Transition Accompanied by Metal - Insulator Transition in PrRu4P12 (2000)

Lee, C. H., Matsuhata, H., Yamamoto, A., Ohta, T., Takazawa, H., Ueno, K., ...

A structural phase transition has been found using electron diffraction technique in PrRu4P12 accompanied by a metal - insulator (M - I) transition (TMI = 60K). Weak superlattice spots appeared at...

A Calculation on the Self-field of a Point Charge and the Unruh Effect (1999)

Hirayama, T., Hara, T.

Within the context of quantum field theory in curved spacetimes, Hacyan and Sarmiento defined the vacuum stress-energy tensor with respect to the accelerated observer. They calculated it for uniform...

Characterization of the YbBa2Cu3O7-y and YBa2Cu3O7-y thin superconducting films prepared by chemical solution deposition on MgO(001) substrate (1999)

Ma, X. L., Yamagiwa, K., Shibata, J., Hirayama, T., Hirabayashi, I., Ikuhara, Y.

Thin superconducting films of the YbBa2Cu3O7−y (Yb 123) and YbBa2Cu3O7−y (Y123), prepared by post-deposition annealing of the metal naphthenates gels spin-coated on MgO(001) substrate, have been...

Low-Temperature Conductivity of ZnO Films Prepared by Chemical Vapor Deposition. (1998)

Natsume, Y., Sakata, H., Hirayama, T., Yanagida, H.

C-axis-oriented ZnO films were prepared in O2 atmosphere by chemical vapor deposition using zinc acetylacetonate for source material. A minimum value of resistivity, 2.44 ohm cm, was obtained at a...

A Model with Simultaneous Dynamical Breaking of Supersymmetry and GUT Gauge Symmetry (1998)

Hirayama, T., Ishimura, N., Maekawa, N.

We try to construct a model in which supersymmetry and grand unified gauge symmetry are dynamically broken at the same time. In this model SUSY breaking is mediated mainly by massive vector...

A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana.

Mizoguchi, T, Irie, K, Hirayama, T, Hayashida, N, Yamaguchi-Shinozaki, K, Matsumoto, K, ...

We describe here the cloning and characterization of a cDNA encoding a protein kinase that has high sequence homology to members of the mitogen-activated protein kinase (MAPK) kinase kinase (MAPKKK...

A gene encoding a phosphatidylinositol-specific phospholipase C is induced by dehydration and salt stress in Arabidopsis thaliana.

Hirayama, T, Ohto, C, Mizoguchi, T, Shinozaki, K

A cDNA corresponding to a putative phosphatidylinositol-specific phospholipase C (PI-PLC) in the higher plant Arabidopsis thaliana was cloned by use of the polymerase chain reaction. The cDNA,...

A transmembrane hybrid-type histidine kinase in Arabidopsis functions as an osmosensor.

Urao, T, Yakubov, B, Satoh, R, Yamaguchi-Shinozaki, K, Seki, M, Hirayama, T, ...

Water deficit and the resulting osmotic stress affect plant growth. To understand how plant cells monitor and respond to osmotic change from water stress, we isolated a cDNA from dehydrated...

Evaluation of susceptibility of gram-positive and -negative bacteria to human defensins by using radial diffusion assay.

Takemura, H, Kaku, M, Kohno, S, Hirakata, Y, Tanaka, H, Yoshida, R, ...

Defensins are small cationic bactericidal peptides present abundantly in the granules of polymorphonuclear neutrophils (PMNs). Human PMNs contain four defensins termed HNP-1 to HNP-4. We used a new...

A classical strain of Vibrio cholerae with diminished ability to process the proteolytically sensitive site in the A subunit of cholera toxin.

Ichinose, Y, Tsuji, T, Kato, M, Neves, B C, Morita, K, Ehara, M, ...

Vibrio cholerae O1, No. 31, a strain isolated from a patient with mild diarrhea, produced mainly the unnicked cholera toxin. The amount of toxin that had accumulated in the cells was approximately...

Identification of ligand recognition sites in heat-stable enterotoxin receptor, membrane-associated guanylyl cyclase C by site-directed mutational analysis.

Wada, A, Hirayama, T, Kitaura, H, Fujisawa, J, Hasegawa, M, Hidaka, Y, ...

Guanylyl cyclase C (STaR), a receptor protein for heat-stable enterotoxin (STa) elaborated by Escherichia coli, is associated with and spans the plasma membrane of mammalian intestinal cells. The...

Nitrite reductase from Pseudomonas aeruginosa induces inflammatory cytokines in cultured respiratory cells.

Oishi, K, Sar, B, Wada, A, Hidaka, Y, Matsumoto, S, Amano, H, ...

Persistent infection with Pseudomonas aeruginosa increases interleukin-8 (IL-8) levels and causes dense neutrophil infiltrations in the airway of patients with chronic airway diseases. To investigate...

Glycoprotein receptors for a heat-stable enterotoxin (STh) produced by enterotoxigenic Escherichia coli.

Hirayama, T, Wada, A, Iwata, N, Takasaki, S, Shimonishi, Y, Takeda, Y

Glycoprotein receptors for heat-stable enterotoxin STh of enterotoxigenic Escherichia coli in the rat intestinal cell membrane were identified and characterized. Incubation of rat intestinal cell...

Binding of pseudomonal leukocidin to rabbit polymorphonuclear leukocytes.

Hirayama, T, Noda, M, Matsuda, F, Nagamori, M, Kato, I

The leukocytotoxic toxin pseudomonal leukocidin, produced by Pseudomonas aeruginosa, was radioiodinated with chloramine-T reagent. Binding of [125I]leukocidin to rabbit polymorphonuclear leukocytes...

An early effect of the S component of staphylococcal leukocidin on methylation of phospholipid in various leukocytes.

Noda, M, Hirayama, T, Matsuda, F, Kato, I

On incubation of rabbit polymorphonuclear leukocytes with the S component of staphylococcal leukocidin at 37 degrees C, the 3H-labeled methyl group of S-adenosyl[methyl-3H]methionine was rapidly...

Mode of cytotoxic action of pseudomonal leukocidin on phosphatidylinositol metabolism and activation of lysosomal enzyme in rabbit leukocytes.

Hirayama, T, Kato, I

The cytotoxic action of leukocidin from Pseudomonas aeruginosa was supported by the following observations. (i) The destruction of rabbit leukocytes by the toxin was reduced in the absence of Ca2+...

Production of leukocidin by clinical isolates of Pseudomonas aeruginosa and antileukocidin antibody from sera of patients with diffuse panbronchiolitis.

Homma, J Y, Matsuura, M, Shibata, M, Kazuyama, Y, Yamamoto, M, Kubota, Y, ...

The ratio of leukocidin-producing strains to clinical isolates of Pseudomonas aeruginosa was investigated together with the production of protease, elastase, and exotoxin A. We also examined whether...

Molecular epidemiologic evidence for association of thermostable direct hemolysin (TDH) and TDH-related hemolysin of Vibrio parahaemolyticus with gastroenteritis.

Shirai, H, Ito, H, Hirayama, T, Nakamoto, Y, Nakabayashi, N, Kumagai, K, ...

The Kanagawa phenomenon induced by the thermostable direct hemolysin (TDH) of Vibrio parahaemolyticus is almost exclusively associated with clinical strains, and TDH has been considered an important...

Mode of action of staphylococcal leukocidin: effects of the S and F components on the activities of membrane-associated enzymes of rabbit polymorphonuclear leukocytes.

Noda, M, Kato, I, Hirayama, T, Matsuda, F

The cytotoxic action of the S component of leukocidin from Staphylococcus aureus on rabbit polymorphonuclear leukocytes was supported by the following observations, (i) Leukocytes displayed a large...

Non-smoking wives of heavy smokers have a higher risk of lung cancer: a study from Japan.

Hirayama, T

In a study in 29 health centre districts in Japan 91 540 non-smoking wives aged 40 and above were followed up for 14 years (1966-79), and standardised mortality rates for lung cancer were assessed...

Quantification of two aromatic amine mutagens, PBTA-1 and PBTA-2, in the yodo river system.

Ohe, T, Takeuchi, N, Watanabe, T, Tada, A, Nukaya, H, Terao, Y, ...

The levels of two aromatic amine mutagens, 2-[2-(acetylamino)-4-[bis(2-methoxyethyl)amino]-5-methoxyphenyl]-5-am ino-7-bromo-4-chloro-2H-benzotriazole (PBTA-1) and...

Cigarette smoking and cancer mortality risk in Japanese men and women--results from reanalysis of the six-prefecture cohort study data.

Akiba, S, Hirayama, T

In 1965 a cohort of 265,000 residents of 29 public health districts in six prefectures throughout Japan was established and followed between 1966 and 1981. By using survival analysis based on Poisson...

Cancer epidemiology in Japan.

Hirayama, T

Patterns, change in occurrence, causative risk factors, and control strategy for cancer of each site in Japanese populations were studied by applying standard methods and techniques of biostatistics...

A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana.

Mizoguchi, T, Irie, K, Hirayama, T, Hayashida, N, Yamaguchi-Shinozaki, K, Matsumoto, K, ...

We describe here the cloning and characterization of a cDNA encoding a protein kinase that has high sequence homology to members of the mitogen-activated protein kinase (MAPK) kinase kinase (MAPKKK...

A gene encoding a phosphatidylinositol-specific phospholipase C is induced by dehydration and salt stress in Arabidopsis thaliana.

Hirayama, T, Ohto, C, Mizoguchi, T, Shinozaki, K

A cDNA corresponding to a putative phosphatidylinositol-specific phospholipase C (PI-PLC) in the higher plant Arabidopsis thaliana was cloned by use of the polymerase chain reaction. The cDNA,...

A transmembrane hybrid-type histidine kinase in Arabidopsis functions as an osmosensor.

Urao, T, Yakubov, B, Satoh, R, Yamaguchi-Shinozaki, K, Seki, M, Hirayama, T, ...

Water deficit and the resulting osmotic stress affect plant growth. To understand how plant cells monitor and respond to osmotic change from water stress, we isolated a cDNA from dehydrated...

Evaluation of susceptibility of gram-positive and -negative bacteria to human defensins by using radial diffusion assay.

Takemura, H, Kaku, M, Kohno, S, Hirakata, Y, Tanaka, H, Yoshida, R, ...

Defensins are small cationic bactericidal peptides present abundantly in the granules of polymorphonuclear neutrophils (PMNs). Human PMNs contain four defensins termed HNP-1 to HNP-4. We used a new...

A classical strain of Vibrio cholerae with diminished ability to process the proteolytically sensitive site in the A subunit of cholera toxin.

Ichinose, Y, Tsuji, T, Kato, M, Neves, B C, Morita, K, Ehara, M, ...

Vibrio cholerae O1, No. 31, a strain isolated from a patient with mild diarrhea, produced mainly the unnicked cholera toxin. The amount of toxin that had accumulated in the cells was approximately...

Identification of ligand recognition sites in heat-stable enterotoxin receptor, membrane-associated guanylyl cyclase C by site-directed mutational analysis.

Wada, A, Hirayama, T, Kitaura, H, Fujisawa, J, Hasegawa, M, Hidaka, Y, ...

Guanylyl cyclase C (STaR), a receptor protein for heat-stable enterotoxin (STa) elaborated by Escherichia coli, is associated with and spans the plasma membrane of mammalian intestinal cells. The...

Nitrite reductase from Pseudomonas aeruginosa induces inflammatory cytokines in cultured respiratory cells.

Oishi, K, Sar, B, Wada, A, Hidaka, Y, Matsumoto, S, Amano, H, ...

Persistent infection with Pseudomonas aeruginosa increases interleukin-8 (IL-8) levels and causes dense neutrophil infiltrations in the airway of patients with chronic airway diseases. To investigate...

Glycoprotein receptors for a heat-stable enterotoxin (STh) produced by enterotoxigenic Escherichia coli.

Hirayama, T, Wada, A, Iwata, N, Takasaki, S, Shimonishi, Y, Takeda, Y

Glycoprotein receptors for heat-stable enterotoxin STh of enterotoxigenic Escherichia coli in the rat intestinal cell membrane were identified and characterized. Incubation of rat intestinal cell...

Binding of pseudomonal leukocidin to rabbit polymorphonuclear leukocytes.

Hirayama, T, Noda, M, Matsuda, F, Nagamori, M, Kato, I

The leukocytotoxic toxin pseudomonal leukocidin, produced by Pseudomonas aeruginosa, was radioiodinated with chloramine-T reagent. Binding of [125I]leukocidin to rabbit polymorphonuclear leukocytes...

An early effect of the S component of staphylococcal leukocidin on methylation of phospholipid in various leukocytes.

Noda, M, Hirayama, T, Matsuda, F, Kato, I

On incubation of rabbit polymorphonuclear leukocytes with the S component of staphylococcal leukocidin at 37 degrees C, the 3H-labeled methyl group of S-adenosyl[methyl-3H]methionine was rapidly...

Mode of cytotoxic action of pseudomonal leukocidin on phosphatidylinositol metabolism and activation of lysosomal enzyme in rabbit leukocytes.

Hirayama, T, Kato, I

The cytotoxic action of leukocidin from Pseudomonas aeruginosa was supported by the following observations. (i) The destruction of rabbit leukocytes by the toxin was reduced in the absence of Ca2+...

Production of leukocidin by clinical isolates of Pseudomonas aeruginosa and antileukocidin antibody from sera of patients with diffuse panbronchiolitis.

Homma, J Y, Matsuura, M, Shibata, M, Kazuyama, Y, Yamamoto, M, Kubota, Y, ...

The ratio of leukocidin-producing strains to clinical isolates of Pseudomonas aeruginosa was investigated together with the production of protease, elastase, and exotoxin A. We also examined whether...

Molecular epidemiologic evidence for association of thermostable direct hemolysin (TDH) and TDH-related hemolysin of Vibrio parahaemolyticus with gastroenteritis.

Shirai, H, Ito, H, Hirayama, T, Nakamoto, Y, Nakabayashi, N, Kumagai, K, ...

The Kanagawa phenomenon induced by the thermostable direct hemolysin (TDH) of Vibrio parahaemolyticus is almost exclusively associated with clinical strains, and TDH has been considered an important...

Mode of action of staphylococcal leukocidin: effects of the S and F components on the activities of membrane-associated enzymes of rabbit polymorphonuclear leukocytes.

Noda, M, Kato, I, Hirayama, T, Matsuda, F

The cytotoxic action of the S component of leukocidin from Staphylococcus aureus on rabbit polymorphonuclear leukocytes was supported by the following observations, (i) Leukocytes displayed a large...

Non-smoking wives of heavy smokers have a higher risk of lung cancer: a study from Japan.

Hirayama, T

In a study in 29 health centre districts in Japan 91 540 non-smoking wives aged 40 and above were followed up for 14 years (1966-79), and standardised mortality rates for lung cancer were assessed...

Quantification of two aromatic amine mutagens, PBTA-1 and PBTA-2, in the yodo river system.

Ohe, T, Takeuchi, N, Watanabe, T, Tada, A, Nukaya, H, Terao, Y, ...

The levels of two aromatic amine mutagens, 2-[2-(acetylamino)-4-[bis(2-methoxyethyl)amino]-5-methoxyphenyl]-5-am ino-7-bromo-4-chloro-2H-benzotriazole (PBTA-1) and...

Cigarette smoking and cancer mortality risk in Japanese men and women--results from reanalysis of the six-prefecture cohort study data.

Akiba, S, Hirayama, T

In 1965 a cohort of 265,000 residents of 29 public health districts in six prefectures throughout Japan was established and followed between 1966 and 1981. By using survival analysis based on Poisson...

Cancer epidemiology in Japan.

Hirayama, T

Patterns, change in occurrence, causative risk factors, and control strategy for cancer of each site in Japanese populations were studied by applying standard methods and techniques of biostatistics...

Expression of human β-defensin 2 (hBD-2) in Helicobacter pylori induced gastritis: antibacterial effect of hBD-2 against Helicobacter pylori

Hamanaka, Y, Nakashima, M, Wada, A, Ito, M, Kurazono, H, Hojo, H, ...

BACKGROUND—Human β-defensin 2 (hBD-2) plays a role in the innate defence system at mucosal surfaces. Colonisation of Helicobacter pylori in the stomach is an important pathological factor in...

IL-6 mRNA synthesis by peripheral blood mononuclear cells (PBMC) in patients with chronic renal failure

YAMAGUCHI, T, IWANO, M, KUBO, A, HIRAYAMA, T, AKAI, Y, HORII, Y, ...

We measured levels of IL-6 mRNA in PBMC obtained from patients with chronic renal failure, using polymerase chain reaction (PCR), PBMC were isolated from 45 patients on haemodialysis (HD) at the...

Corticospinal direct response in humans: identification of the motor cortex during intracranial surgery under general anaesthesia.

Katayama, Y, Tsubokawa, T, Maejima, S, Hirayama, T, Yamamoto, T

The corticospinal direct (D) response to stimulation of the motor cortex exposed for intracranial surgery was recorded in 20 cases from wire electrodes inserted into the spinal epidural space. The D...