Gutzwiller, Chaos in Classical and Quantum Mechanics (2009)
B. L. Altshuler, B. D. Simons, In Mesoscopic, Quantum Physics, E. Akkermans, G. Montambaux, ...
2. For recent reviews discussing the connection between
Directional Voting with Geometric Hashing for Three Dimensional Object Recognition (2009)
S. Kaneko, M. Shibata, T. Honda
the combinations of triplets of basis points from the set of feature points and then the HT can include normalized A new method for recognition of three dimensional information of feature...
Development of 40 inch hybrid hologram screen for auto stereoscopic video display (2008)
Hyun Ho. Song, Y. Nakashima, Y. Momonoi, T. Honda, Manku Dowhadong Incheon
Usually in auto stereoscopic display, there are two problems. The first problem is that large image display is difficult, and the second problem is that the view zone (which means the zone in which...
Matsumoto, T, Matsubara, M, Oana, K, Kasuga, E, Suzuki, T, Hidaka, E, ...
Progressive pulmonary calcification after successful renal transplantation (2008)
Yasuo, M, Tanabe, T, Komatsu, Y, Tsushima, K, Kubo, K, Takahashi, K, ...
Fujimoto, K, Yoshiike, F, Yasuo, M, Kitaguchi, Y, Urushihata, K, Kubo, K, ...
‘The definitive version is available at www.blackwell-synergy.com '.
Matsumoto, T, Kawakami, Y, Oana, K, Honda, T, Yamauchi, K, Okimura, Y, ...
Rinde, J. E., Coppola, P. S., Musser, E., Wildrick, M., Honda, T.
The objective of this study and investigation was to develop dual fault corrective capability for increased reliability by applying redundancy at the element level in flight control actuation...
Fukui, T, Shiraki, K, Hamada, D, Hara, K, Miyata, T, Fujiwara, S, ...
Yamazaki, K, Honda, T, Oda, T, Ueki-Maruyama, K, Nakajima, T, Yoshie, H, ...
Background: Recent epidemiological studies have shown that individuals with periodontitis have a significantly increased risk of developing coronary heart disease. In addition to conventional risk...
Hayashi, K., Tayama, R., Shibata, K., Honda, T., Morimoto, M., Izumida, T., ...
In recent years, positron-emitting labelled radiopharmaceuticals have come to be used in conjunction with positron emission tomography (PET) in various clinical diagnoses. Radiation exposure of the...
Dendritic side-branching with anisotropic viscous fingering (2004)
Honda, T., Honjo, H., Katsuragi, H.
We studied dendritic side-branching mechanism in the experiment of anisotropic viscous fingering. We measured the time dependence of growth speed of side-branch and the envelop of side-branches. We...
Sone, T, Yoshida, S, Yahata, K, Chesnut, JD, ...
Six types of recombination signal DNA sequences of the Multisite Gateway cloning system were investigated as to their specificity and efficiency in the LR and BP recombination reactions. In the LR...
Effect of periodontal treatment on the serum antibody levels to heat shock proteins (2004)
Yamazaki, K, Ueki-Maruayama, K, Honda, T, Nakajima, T, Seymour, GJ
We have shown previously that both humoral and cellular immune responses to heat shock protein 60 (HSP60) are elevated in chronic periodontitis patients compared with non-diseased subjects. The aim...
Asahi, K, Ueno, H, Sakai, H, Miyoshi, H, Kameda, D, ...
The electric quadrupole moment of B-17 and the g-factor of C-17 were measured by using the fragmentation-induced nuclear polarization technique combined with the beta-NMR method. The experimental...
Y. Kodama, D. Pawel, N. Nakamura, D. Preston, T. Honda, M. Itoh, ...
Kodama, Y., Pawel, D., Nakamura, N., Preston, D., Honda, T., Itoh, M., Nakano, M., Ohtaki, K., Funamoto, S. and Awa, A. A. Stable Chromosome Aberrations in Atomic Bomb Survivors: Results from 25...
Endoh, H., Honda, T., Oohashi, S., Nagata, Y., Shibue, C., Shimoji, K.
We measured the accuracy of the continuous intra‐vascular blood‐gas monitoring system (Paratrend 7, PT7) placed in the jugular venous bulb in 18 adult patients having cardiac or aortic...
Coulomb explosion of a cluster irradiated by a high intensity laser pulse (2000)
Esirkepov, T, Bingham, R, Bulanov, S, Honda, T, Nishihara, K, Pegoraro, F
Dry sliding wear behavior of $Al_{2}O_{3}$ fiber reinforced aluminum composites (2000)
Iwai, Y, Honda, T, Miyajima, T, Iwasaki, Y, Surappa, MK, Xu, JF
Dry sliding wear behavior of die-cast ADC12 aluminum alloy composites reinforced with short alumina fibers were investigated by using a pin-on-disk wear tester. The Al2O3 fibers were 4 mu m in...
Maximum-density droplet and charge redistributions in quantum dots at high magnetic fields (1999)
Oosterkamp, T.H., Janssen, J.W., Kouwenhoven, L.P., Austing, D.G., Honda, T., Tarucha, S.
Operation of the photon factory with a high brilliance optics (1998)
Katoh, M, Hori, Y, Asaoka, S, Haga, K, Honda, T, Izawa, M, ...
Global feedback system for photon factory storage ring (1998)
Obina, T, Haga, K, Honda, T, Tadano, M, Kasuga, T, Katoh, M, ...
High Performance 4600 Steels by Injection Molding. (1998)
Miura, H., Honda, T., Hens, K. F., German, R. M.
This study with powder injection molding considers the combined influences of type of powders and subsequent debinding and sintering conditions on the control of carbon content and structure for 4600...
Effect of Pb on High-Tc Phase Formation and Properties of Bi(2(1-x))Pb(2x)Sr2Ca2Cu3O(y). (1998)
Honda, T., Meskoob, M., Safari, A., Wachtman, J. B.
We prepared Bi(2(1-x))Pb(2x)Sr2Cu3O(y) (x=0, 0.1, 0.2, 0.3, and 0.5) by conventional solid state reactions with various firing temperatures and carried out X-ray diffraction analysis and resistivity...
Stability of the maximum density droplet in quantum dots at high magnetic fields (1998)
Oosterkamp, T. H., Janssen, J. W., Kouwenhoven, L. P., Austing, D. G., Honda, T., Tarucha, S.
We have measured electron transport through a vertical quantum dot containing a tunable number of electrons between 0 and 40. Over some region in magnetic field the electrons are spin polarized and...
Commissioning of the photon factory with a high brilliance optics (1998)
Katoh, M, Hori, Y, Asaoka, S, Haga, K, Honda, T, Izawa, M, ...
Single-pass BPM system of the Photon Factory storage ring (1998)
Honda, T, Katoh, M, Mitsuhashi, T, Ueda, A, Tadano, M, Kobayashi, Y
Measurement of injection orbit using a single pass BPM system at the PF ring (1998)
Honda, T, Katoh, M, Ueda, A, Tadano, M, Kobayashi, Y, Mitsuhashi, T
Non-isochromaticity of an omega filter in a 200 kV transmission electron microscope (1998)
Tsuno, K., Kaneyama, T., Honda, T., Ishida, Y.
Non-isochromaticity of a newly developed energy filtering transmission electron microscope (EFTEM), JEM2010FEF, has been evaluated. The nonisochromaticity is the difference in energy from position to...
Yamada, S, Fujiwara, H, Ueda, M, Honda, T, Nakayama, T, Higuchi, T, ...
Yamada, S, Fujiwara, H, Kataoka, N, Honda, T, Nakayama, T, Higuchi, T, ...
Spontaneous regression of primary mediastinal germ cell tumor (1998)
Hachiya, T, Koizumi, T, Hayasaka, M, Kubo, K, Sekiguchi, M, Hanyuuda, M, ...
Excitation Spectra of Circular Few-Electron Quantum Dots (1997)
Kouwenhoven, L. P., Oosterkamp, T. H., Danoesastro, M. W. S., Eto, M., Austing, D. G., Honda, T., ...
We study ground states and excited states in semiconductor quantum dots containing 1 to 12 electrons. For the first time, it is possible to identify the quantum numbers of the states in the...
Results of Endoscopic Treatment for Early Gastric Cancer by Nd-YAG Laser (1997)
M. Tani, K. Takeshita, T. Honda, N. Saito, M. Endo
We have introduced two endoscopic treatments for early gastric cancer: endoscopic mucosal resection using a cap-fitted panendoscope (EMRC), and endoscopic laser therapy using a Nd-YAG laser....
Design and testing of Omega mode imaging energy filters at 200 kV (1997)
Tsuno, K., Kaneyama, T., Honda, T., Tsuda, K., Terauchi, M., Tanaka, M.
We designed and constructed an omega filter with following optical properties. The dispersions at 100 and 200 kV are 2.1 and 1.1 μm eV-1, respectively. Non-isochromatisity (difference of the...
Honda, T, Fujiwara, H, Yamada, S, Fujita, K, Nakamura, K, Nakayama, T, ...
A single-pass beam position monitor for the injection beam at the photon factory storage ring (1996)
Shell filling and spin effects in a few electron quantum dot (1996)
Tarucha, S., Austing, D.G., Honda, T., Van Der Hage, R.J., Kouwenhoven, L.P.
Ketamine inhibits nitric oxide production in mouse-activated macrophage- like cells (1996)
Shimaoka, M., Iida, T., Ohara, A., Taenaka, N., Mashimo, T., Honda, T., ...
SANG, W. K., SAIDI, S. M., YAMAMOTO, H., EZAKI, T., IIDA, T., YOH, M., ...
Beam position feedback systems for the PF storage ring (1995)
Nakamura, N, Haga, K, Honda, T, Kasuga, T, Katoh, M, Kobayashi, Y, ...
Honda, T., Okano, T., Tuzi, Y.
Surface diffusion of Ga atoms on a Ge(100) plane was studied by using digital autocorrelation analysis of field-emitted electrons. The present method was based on pulse-counting of field-emitted...
Honda, T., Okano, T., Tuzi, Y.
Surface diffusion of Ga atoms on a Ge(100) plane was studied by using digital autocorrelation analysis of field-emitted electrons. The present method was based on pulse-counting of field-emitted...
Honda, T., Okano, T., Tuzi, Y.
Surface diffusion of Ga atoms on a Ge(100) plane was studied by using digital autocorrelation analysis of field-emitted electrons. The present method was based on pulse-counting of field-emitted...
GAMMA-RAY COMPTON SCATTERING OF GERMANIUM AND SELENIUM IN SOLID AND LIQUID STATE (1980)
Itoh, F., Honda, T., Suzuki, K.
No abstract available
GAMMA-RAY COMPTON SCATTERING OF GERMANIUM AND SELENIUM IN SOLID AND LIQUID STATE (1980)
Itoh, F., Honda, T., Suzuki, K.
No abstract available
GAMMA-RAY COMPTON SCATTERING OF GERMANIUM AND SELENIUM IN SOLID AND LIQUID STATE (1980)
Itoh, F., Honda, T., Suzuki, K.
No abstract available
MECANISMES D'INTERACTION DANS LA REACTION 11B (p, α) 8Be (0+) (1970)
Cavaignac, J., Longequeue, N., Honda, T.
La réaction 11B (p, α) 8Be (0+) est étudiée à Ep = 12, 20, 24 e t 30 MeV. Une analyse par ondes planes réalisée en tenant compte des processus de "Pick- up" et "heavy particle pick up"...
MECANISMES D'INTERACTION DANS LA REACTION 11B (p, α) 8Be (0+) (1970)
Cavaignac, J., Longequeue, N., Honda, T.
La réaction 11B (p, α) 8Be (0+) est étudiée à Ep = 12, 20, 24 e t 30 MeV. Une analyse par ondes planes réalisée en tenant compte des processus de "Pick- up" et "heavy particle pick up"...
MECANISMES D'INTERACTION DANS LA REACTION 11B (p, α) 8Be (0+) (1970)
Cavaignac, J., Longequeue, N., Honda, T.
La réaction 11B (p, α) 8Be (0+) est étudiée à Ep = 12, 20, 24 e t 30 MeV. Une analyse par ondes planes réalisée en tenant compte des processus de "Pick- up" et "heavy particle pick up"...
Collins, J F, Honda, T, Knobel, S, Bulus, N M, Conary, J, DuBois, R, ...
The present studies demonstrate cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger which was isolated from a rat intestinal cDNA library. The cloned cDNA...
Honda, T, Miwatani, T, Yabushita, Y, Koike, N, Okada, K
A new method of chemically immobilizing antibody on nylon was developed. The method consists of serial treatments with HCl, polyethylene imine, and maleic anhydride methylvinyl ether copolymer, which...
Taniguchi, T, Fujino, Y, Yamamoto, K, Miwatani, T, Honda, T
The plasmid-encoded structural gene cofA necessary for the production of the major pilin subunit of pilus colonization factor antigen III (CFA/III) of human enterotoxigenic Escherichia coli was...
Purification and characterization of a cell-associated hemagglutinin of Vibrio parahaemolyticus.
Nagayama, K, Oguchi, T, Arita, M, Honda, T
We found a positive correlation between cell-associated mannose-sensitive hemagglutination and adherence of Vibrio parahaemolyticus to rabbit enterocytes by investigating 35 strains of V....
Nagamune, K, Yamamoto, K, Naka, A, Matsuyama, J, Miwatani, T, Honda, T
Vibrio cholerae produces a cytolytic toxin named El Tor cytolysin/hemolysin which is encoded by the hlyA gene. This cytolysin is produced as a 79-kDa precursor form (pro-HlyA) into the culture...
Minami, A, Hashimoto, S, Abe, H, Arita, M, Taniguchi, T, Honda, T, ...
Vibrio cholerae O1 strains isolated from various sources in Japan over the years 1977 through 1987 were examined to confirm the presence or absence of the cholera enterotoxin (CT) gene and production...
Xu, M, Iida, T, Yamamoto, K, Takarada, Y, Miwatani, T, Honda, T
Simultaneous production of a thermostable direct hemolysin (TDH)-like toxin (TDHx) and a TDH-related hemolysin (TRH)-like toxin (TRHx) by a clinical isolate (strain TH3766) of Kanagawa...
A mutant, Vp-MX02, having a deletion in the gene (trh) for the thermostable direct hemolysin-related hemolysin (TRH) was constructed by double-crossover gene conversion from a TRH-producing Vibrio...
Yoh, M, Honda, T, Miwatani, T, Tsunasawa, S, Sakiyama, F
Vibrio hollisae produces a hemolysin (Vh-rTDH) that is related to the thermostable direct hemolysin of Vibrio parahaemolyticus (Vp-TDH). Although both hemolysins are essentially similar biologically...
Okamoto, K, Okamoto, K, Miyama, A, Tsuji, T, Honda, T, Miwatani, T
The ADP-ribosyltransferase activity of polypeptide A1 of cholera toxin and that of Escherichia coli heat-labile enterotoxin (LT) are primarily responsible for the toxic activities of these toxins....
Suthienkul, O, Iida, T, Park, K S, Ishibashi, M, Supavej, S, Yamamoto, K, ...
The restriction fragment length polymorphism of the genes encoding thermostable direct hemolysin (tdh) and thermostable direct hemolysin-related hemolysin (trh) was analyzed for 137 strains of Vibrio...
Nagayama, K, Bi, Z, Oguchi, T, Takarada, Y, Shibata, S, Honda, T
An alkaline phosphatase-conjugated 29-base oligonucleotide probe was developed to detect the gene encoding the bundle-forming pilus of enteropathogenic Escherichia coli. The sensitivity and...
Honda, T, Nishibuchi, M, Miwatani, T, Kaper, J B
Of 15 Vibrio cholerae non-O1 strains, 2 produced a hemolysin termed NAG-rTDH, which is very similar to the thermostable direct hemolysin of V. parahaemolyticus. These two strains contained DNA...
Arita, M, Honda, T, Miwatani, T, Ohmori, K, Takao, T, Shimonishi, Y
The possible production of a heat-stable enterotoxin (Vc-H-ST) by Vibrio cholerae non-O1 serogroup Hakata was investigated, and the purified Vc-H-ST was characterized. It has a unique amino acid...
Purification and characterization of Vibrio metschnikovii cytolysin.
Miyake, M, Honda, T, Miwatani, T
An extracellular cytolysin produced by Vibrio metschnikovii was purified by acid precipitation, phenyl-Sepharose CL-4B chromatography, and rechromatography on a phenyl-Sepharose CL-4B column and...
Honda, T, Ni, Y X, Miwatani, T
A clinical isolate (strain 4037) of Kanagawa phenomenon-negative Vibrio parahaemolyticus was studied. Although the strain was judged to be Kanagawa phenomenon-negative by various conventional tests,...
Isolation of Shiga toxin-resistant Vero cells and their use for easy identification of the toxin.
Kongmuang, U, Honda, T, Miwatani, T
Shiga toxin-resistant Vero cells were isolated by treatment of the cells with nitrosoguanidine. These mutant cells were not affected by Shiga toxin at more than 1 microgram/ml, although the parent...
Honda, T, Wetprasit, N, Arita, M, Miwatani, T
Three monoclonal antibodies (MAbs) to a pilus colonization factor (colonization factor antigen III [CFA/III]) of human enterotoxigenic Escherichia coli (ETEC) were developed and characterized. All of...
Honda, T, Booth, B A, Boesman-Finkelstein, M, Finkelstein, R A
Protease and soluble hemagglutinating activities produced by a non-O1 Vibrio cholerae strain isolated from a patient with diarrhea were compared with similar activities produced by V. cholerae O1....
Tsuji, T, Honda, T, Miwatani, T
The effect on nicking (proteolytic cleavage) of heat-labile enterotoxin (LT) on its activities on Chinese hamster ovary (CHO) cells was examined. LT nicked with trypsin induced morphological change...
Honda, T, Sato, M, Nishimura, T, Higashitsutsumi, M, Fukai, K, Miwatani, T
The production of toxins by Aeromonas species was examined by the suckling mouse test, the hemolysin test, and the enzyme-linked immunosorbent assay with anticholera enterotoxin. A factor that was...
Purification and characterization of Vibrio cholerae non-O1 heat-stable enterotoxin.
Arita, M, Takeda, T, Honda, T, Miwatani, T
A toxin which causes rapid fluid accumulation in a suckling mouse assay and which was produced by Vibrio cholerae non-O1 was investigated. The toxin was purified from the culture supernatant of V....
A newly identified hemolysin (NAG-rTDH), which is related to the thermostable direct hemolysin (Vp-TDH) of Vibrio parahaemolyticus produced by non-O1 Vibrio cholerae, was studied. NAG-rTDH was...
Development of an enzyme-labeled oligonucleotide probe for the cholera toxin gene.
Yoh, M, Miyagi, K, Matsumoto, Y, Hayashi, K, Takarada, Y, Yamamoto, K, ...
An alkaline phosphatase-conjugated 30-mer oligonucleotide probe was developed to detect the cholera toxin gene (ctx) in Vibrio cholerae O1. For rapid identification, V. cholerae O1 was grown on...
Yamamoto, K, Al-Omani, M, Honda, T, Takeda, Y, Miwatani, T
Hemolysin of a non-O1 Vibrio cholerae strain was purified and characterized. The purified hemolysin gave a single protein band on conventional and sodium dodecyl sulfate-gel electrophoresis. Its...
Shimaoka, M, Yoh, M, Segawa, A, Takarada, Y, Yamamoto, K, Honda, T
A DNA hybridization method with an enzyme-labeled oligonucleotide probe (mecA-ELONP) was developed to detect the methicillin-resistant gene (mecA) in methicillin-resistant Staphylococcus aureus. For...
Honda, T, Arita, M, Miwatani, T
Enterotoxigenic Escherichia coli strains were divided into five groups on the basis of their bacterial surface hydrophobicity (Honda et al., FEMS Microbiol. Lett. 17:273-276, 1983). Strains in group...
Levine, M M, Black, R E, Clements, M L, Lanata, C, Sears, S, Honda, T, ...
Texas Star-SR, an A- B+ mutant derived by nitrosoguanidine treatment from Vibrio cholerae El Tor Ogawa strain 3083, was fed to 68 volunteers as an oral vaccine in doses of 10(5) to 5 X 10(10)...
Yoh, M, Yamamoto, K, Honda, T, Takeda, Y, Miwatani, T
Enterotoxigenic Escherichia coli grown in the presence of lincomycin and tetracycline produced an increased amount of heat-labile enterotoxin (LT). These antibiotics increased the production of not...
Takeda, Y, Honda, T, Sima, H, Tsuji, T, Miwatani, T
Antigenic determinants of cholera enterotoxin (CT) and heat-labile enterotoxin from a human strain (LTh) and a porcine strain (LTp) were analyzed by Ouchterlony double-gel diffusion test against...
Enzyme-linked immunosorbent assay to detect Shiga toxin of Shigella dysenteriae and related toxins.
Kongmuang, U, Honda, T, Miwatani, T
A sandwich enzyme-linked immunosorbent assay (ELISA) was developed for detection of Shiga toxin. Four species of Shigella, Escherichia coli, and Vibro parahaemolyticus were tested for production of...
Nishibuchi, M, Arita, M, Honda, T, Miwatani, T
A commercially available, alkaline-phosphatase-conjugated oligonucleotide probe for detecting the heat-stable enterotoxin gene of Escherichia coli was compared with cloned gene probes by examining E....
Nishibuchi, M, Murakami, A, Arita, M, Jikuya, H, Takano, J, Honda, T, ...
We examined variations in the genes encoding heat-stable enterotoxin (ST) and heat-labile enterotoxin (LT) in 88 strains of Escherichia coli isolated from individuals with traveler's diarrhea to find...
Honda, T, Yoh, M, Kongmuang, U, Miwatani, T
Several systems for enzyme-linked immunosorbent assay (ELISA) of thermostable direct hemolysin (TDH) of Vibrio parahaemolyticus were tested, and single-antibody sandwich ELISA systems gave...
Yoh, M, Narita, I, Honda, T, Miwatani, T, Nishibuchi, M
Ten strains of enterotoxigenic Escherichia coli producing heat-labile enterotoxin (LT) were preserved under 12 different conditions. After 1 month, 9 months, and 3 years of preservation, the cultures...
Honda, T, Sato, M, Miwatani, T
Enzyme-linked immunosorbent assays (ELISAs) with antibodies specific to either cholera enterotoxin (CT) of Vibrio cholerae or heat-labile enterotoxin (LT) of enterotoxigenic Escherichia coli were...
Honda, T, Arita, M, Takeda, Y, Miwatani, T
A total of 2,229 strains of Escherichia coli isolated from subjects with traveller's diarrhea were tested for heat-labile enterotoxin production by the Biken test (Honda et al., J. Clin. Microbiol....
Honda, T, Sornchai, C, Takeda, Y, Miwatani, T
Selective media for Vibrio parahaemolyticus, BTB-Teepol agar and modified arabinose-ammonium sulfate-cholate agar, were modified for use in immunological detection of the thermostable direct...
Honda, T, Samakoses, R, Sornchai, C, Takeda, Y, Miwatani, T
For detection of heat-labile enterotoxin-producing enterotoxigenic Escherichia coli, the staphylococcal coagglutination test reported by Brill et al. (J. Clin. Microbiol. 9:49-55, 1979) was modified...
Immunological methods for detection of Kanagawa phenomenon of Vibrio parahaemolyticus.
Honda, T, Chearskul, S, Takeda, Y, Miwatani, T
A modified Elek test and an immuno-halo test were developed for detection of the thermostable direct hemolysin produced by Kanagawa phenomenon-positive strains of Vibrio parahaemolyticus. The...
Modified Elek test for detection of heat-labile enterotoxin of enterotoxigenic Escherichia coli.
Honda, T, Taga, S, Takeda, Y, Miwatani, T
The Elek test was modified for detection of the heat-labile enterotoxin of enterotoxigenic Escherichia coli. A total of 164 strains of E. coli were tested by the modified Elek test, and the results...
Tang, G Q, Iida, T, Yamamoto, K, Honda, T
A mutant toxin, R7, of thermostable direct hemolysin (TDH) with a single amino acid substitution at glycine 62 was analyzed. The hemolytic activity of R7 decreased to less than 1/1,000 of that of...
Miyake, M, Honda, T, Miwatani, T
Divalent cations and polysaccharides such as inulin and dextran reversibly inhibited hemolysis of rabbit erythrocytes caused by Vibrio metschnikovii cytolysin. On the basis of the 50% inhibitory...
Nishibuchi, M, Taniguchi, T, Misawa, T, Khaeomanee-Iam, V, Honda, T, Miwatani, T
Vibrio parahaemolyticus isolates derived from an outbreak of gastroenteritis in the Republic of Maldives did not have the genetic potential to produce the thermostable direct hemolysin, but one such...
Honda, T, Lertpocasombat, K, Hata, A, Miwatani, T, Finkelstein, R A
A protease produced by a clinical isolate of Vibrio cholerae non-O1 was purified to apparent homogeneity by ammonium sulfate fractionation and successive column chromatography on DEAE-Sephadex A25,...
Yamamoto, K, Ichinose, Y, Shinagawa, H, Makino, K, Nakata, A, Iwanaga, M, ...
Vibrio cholerae O1 biotype El Tor produces and secretes a 65-kDa cytolysin/hemolysin into the culture medium. We cloned the structural gene (hlyA) for the cytolysin from the total DNA of a V....
Tsuji, T, Taga, S, Honda, T, Takeda, Y, Miwatani, T
The heat-labile enterotoxins produced by human enterotoxigenic Escherichia coli (LTh) and porcine enterotoxigenic E. coli (LTp) were purified to homogeneity, and their molecular properties were...
Honda, T, Takeda, Y, Miwatani, T
Cholera enterotoxin (CT) and heat-labile enterotoxin (LT) produced by enterotoxigenic Escherichia coli share a common antigenic determinant. In addition, CT and LT each have a unique antigenic...
Honda, T, Tsuji, T, Takeda, Y, Miwatani, T
The Ouchterlony double-gel diffusion test demonstrated that heat-labile enterotoxin (LT) from human strains of enterotoxigenic Escherichia coli was antigenically related but not identical to that...
Takeda, Y, Honda, T, Taga, S, Miwatani, T
Heat-labile enterotoxin (LT) was purified from cells of enterotoxigenic Escherichia coli isolated from a patient with traveller's diarrhea. Purified LT was separated into A and B subunits by...
Takeda, T, Honda, T, Takeda, Y, Miwatani, T
We studied the effect of chlorpromazine on fluid accumulation caused by purified heat-stable enterotoxin (ST) from enterotoxigenic Escherichia coli in suckling mice. We found that chlorpromazine...
After mutagenesis with nitrosoguanidine and selection by immuno-halo techniques, an avirulent mutant, designated Texas Star-SR, which produces no detectable A (active; ADP-ribosylating) region of the...
A thermolabile direct hemolysin from an El Tor cholera vibrio strain has been isolated and partially characterized as a simple protein of ca. 20,000 molecular weight. In addition to its hemolytic...
Takeda, R, Honda, T, Sakural, J, Otomo, N
The hemolytic activity of the thermostable direct hemolysin produced by Vibrio parahaemolyticus was inhibited by a ganglioside mixture. The ganglioside component which inhibited the hemolysin was not...
Honda, T, Shimizu, M, Takeda, Y, Miwatani, T
A factor changing Chinese hamster ovary cells from an oval to a spindle shape was isolated from the culture filtrate of Vibrio parahaemolyticus. It was partially purified by successive column...
Honda, T, Taga, S, Takeda, T, Hasibuan, M A, Takeda, Y, Miwatani, T
Lethal toxin was purified extensively from the culture filtrate of a Kanagawa phenomenon-positive strain of Vibrio parahaemolyticus. The purified toxin was a protein, and its homogeneity was...
Honda, T, Goshima, K, Takeda, Y, Sugino, Y, Miwatani, T
Intravenous injection of the thermostable direct hemolysin (lethal toxin) produced by Vibrio parahaemolyticus caused rapid death of rats. Studies by electroencephalography and electrocardiography...
Sakurai, J, Honda, T, Jinguji, Y, Arita, M, Miwatani, T
The thermostable direct hemolysin produced by Vibrio parahaemolyticus showed cytotoxic activity on FL cells derived from human amniotic membrane. Scanning electron micrographs of the whole cells...
Takeda, Y, Takeda, T, Honda, T, Miwatani, T
Biological activities of the thermostable direct hemolysin produced by Vibrio parahaemolyticus, such as its hemolytic activity and lethal activity, were inhibited by neuraminidase-sensitive...
Collins, J F, Honda, T, Knobel, S, Bulus, N M, Conary, J, DuBois, R, ...
The present studies demonstrate cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger which was isolated from a rat intestinal cDNA library. The cloned cDNA...
Honda, T, Miwatani, T, Yabushita, Y, Koike, N, Okada, K
A new method of chemically immobilizing antibody on nylon was developed. The method consists of serial treatments with HCl, polyethylene imine, and maleic anhydride methylvinyl ether copolymer, which...
Taniguchi, T, Fujino, Y, Yamamoto, K, Miwatani, T, Honda, T
The plasmid-encoded structural gene cofA necessary for the production of the major pilin subunit of pilus colonization factor antigen III (CFA/III) of human enterotoxigenic Escherichia coli was...
Purification and characterization of a cell-associated hemagglutinin of Vibrio parahaemolyticus.
Nagayama, K, Oguchi, T, Arita, M, Honda, T
We found a positive correlation between cell-associated mannose-sensitive hemagglutination and adherence of Vibrio parahaemolyticus to rabbit enterocytes by investigating 35 strains of V....
Nagamune, K, Yamamoto, K, Naka, A, Matsuyama, J, Miwatani, T, Honda, T
Vibrio cholerae produces a cytolytic toxin named El Tor cytolysin/hemolysin which is encoded by the hlyA gene. This cytolysin is produced as a 79-kDa precursor form (pro-HlyA) into the culture...
Minami, A, Hashimoto, S, Abe, H, Arita, M, Taniguchi, T, Honda, T, ...
Vibrio cholerae O1 strains isolated from various sources in Japan over the years 1977 through 1987 were examined to confirm the presence or absence of the cholera enterotoxin (CT) gene and production...
Xu, M, Iida, T, Yamamoto, K, Takarada, Y, Miwatani, T, Honda, T
Simultaneous production of a thermostable direct hemolysin (TDH)-like toxin (TDHx) and a TDH-related hemolysin (TRH)-like toxin (TRHx) by a clinical isolate (strain TH3766) of Kanagawa...
A mutant, Vp-MX02, having a deletion in the gene (trh) for the thermostable direct hemolysin-related hemolysin (TRH) was constructed by double-crossover gene conversion from a TRH-producing Vibrio...
Yoh, M, Honda, T, Miwatani, T, Tsunasawa, S, Sakiyama, F
Vibrio hollisae produces a hemolysin (Vh-rTDH) that is related to the thermostable direct hemolysin of Vibrio parahaemolyticus (Vp-TDH). Although both hemolysins are essentially similar biologically...
Okamoto, K, Okamoto, K, Miyama, A, Tsuji, T, Honda, T, Miwatani, T
The ADP-ribosyltransferase activity of polypeptide A1 of cholera toxin and that of Escherichia coli heat-labile enterotoxin (LT) are primarily responsible for the toxic activities of these toxins....
Suthienkul, O, Iida, T, Park, K S, Ishibashi, M, Supavej, S, Yamamoto, K, ...
The restriction fragment length polymorphism of the genes encoding thermostable direct hemolysin (tdh) and thermostable direct hemolysin-related hemolysin (trh) was analyzed for 137 strains of Vibrio...
Nagayama, K, Bi, Z, Oguchi, T, Takarada, Y, Shibata, S, Honda, T
An alkaline phosphatase-conjugated 29-base oligonucleotide probe was developed to detect the gene encoding the bundle-forming pilus of enteropathogenic Escherichia coli. The sensitivity and...
Honda, T, Nishibuchi, M, Miwatani, T, Kaper, J B
Of 15 Vibrio cholerae non-O1 strains, 2 produced a hemolysin termed NAG-rTDH, which is very similar to the thermostable direct hemolysin of V. parahaemolyticus. These two strains contained DNA...
Arita, M, Honda, T, Miwatani, T, Ohmori, K, Takao, T, Shimonishi, Y
The possible production of a heat-stable enterotoxin (Vc-H-ST) by Vibrio cholerae non-O1 serogroup Hakata was investigated, and the purified Vc-H-ST was characterized. It has a unique amino acid...
Purification and characterization of Vibrio metschnikovii cytolysin.
Miyake, M, Honda, T, Miwatani, T
An extracellular cytolysin produced by Vibrio metschnikovii was purified by acid precipitation, phenyl-Sepharose CL-4B chromatography, and rechromatography on a phenyl-Sepharose CL-4B column and...
Honda, T, Ni, Y X, Miwatani, T
A clinical isolate (strain 4037) of Kanagawa phenomenon-negative Vibrio parahaemolyticus was studied. Although the strain was judged to be Kanagawa phenomenon-negative by various conventional tests,...
Isolation of Shiga toxin-resistant Vero cells and their use for easy identification of the toxin.
Kongmuang, U, Honda, T, Miwatani, T
Shiga toxin-resistant Vero cells were isolated by treatment of the cells with nitrosoguanidine. These mutant cells were not affected by Shiga toxin at more than 1 microgram/ml, although the parent...
Honda, T, Wetprasit, N, Arita, M, Miwatani, T
Three monoclonal antibodies (MAbs) to a pilus colonization factor (colonization factor antigen III [CFA/III]) of human enterotoxigenic Escherichia coli (ETEC) were developed and characterized. All of...
Honda, T, Booth, B A, Boesman-Finkelstein, M, Finkelstein, R A
Protease and soluble hemagglutinating activities produced by a non-O1 Vibrio cholerae strain isolated from a patient with diarrhea were compared with similar activities produced by V. cholerae O1....
Tsuji, T, Honda, T, Miwatani, T
The effect on nicking (proteolytic cleavage) of heat-labile enterotoxin (LT) on its activities on Chinese hamster ovary (CHO) cells was examined. LT nicked with trypsin induced morphological change...
Honda, T, Sato, M, Nishimura, T, Higashitsutsumi, M, Fukai, K, Miwatani, T
The production of toxins by Aeromonas species was examined by the suckling mouse test, the hemolysin test, and the enzyme-linked immunosorbent assay with anticholera enterotoxin. A factor that was...
Purification and characterization of Vibrio cholerae non-O1 heat-stable enterotoxin.
Arita, M, Takeda, T, Honda, T, Miwatani, T
A toxin which causes rapid fluid accumulation in a suckling mouse assay and which was produced by Vibrio cholerae non-O1 was investigated. The toxin was purified from the culture supernatant of V....
A newly identified hemolysin (NAG-rTDH), which is related to the thermostable direct hemolysin (Vp-TDH) of Vibrio parahaemolyticus produced by non-O1 Vibrio cholerae, was studied. NAG-rTDH was...
Development of an enzyme-labeled oligonucleotide probe for the cholera toxin gene.
Yoh, M, Miyagi, K, Matsumoto, Y, Hayashi, K, Takarada, Y, Yamamoto, K, ...
An alkaline phosphatase-conjugated 30-mer oligonucleotide probe was developed to detect the cholera toxin gene (ctx) in Vibrio cholerae O1. For rapid identification, V. cholerae O1 was grown on...
Yamamoto, K, Al-Omani, M, Honda, T, Takeda, Y, Miwatani, T
Hemolysin of a non-O1 Vibrio cholerae strain was purified and characterized. The purified hemolysin gave a single protein band on conventional and sodium dodecyl sulfate-gel electrophoresis. Its...
Shimaoka, M, Yoh, M, Segawa, A, Takarada, Y, Yamamoto, K, Honda, T
A DNA hybridization method with an enzyme-labeled oligonucleotide probe (mecA-ELONP) was developed to detect the methicillin-resistant gene (mecA) in methicillin-resistant Staphylococcus aureus. For...
Honda, T, Arita, M, Miwatani, T
Enterotoxigenic Escherichia coli strains were divided into five groups on the basis of their bacterial surface hydrophobicity (Honda et al., FEMS Microbiol. Lett. 17:273-276, 1983). Strains in group...
Levine, M M, Black, R E, Clements, M L, Lanata, C, Sears, S, Honda, T, ...
Texas Star-SR, an A- B+ mutant derived by nitrosoguanidine treatment from Vibrio cholerae El Tor Ogawa strain 3083, was fed to 68 volunteers as an oral vaccine in doses of 10(5) to 5 X 10(10)...
Yoh, M, Yamamoto, K, Honda, T, Takeda, Y, Miwatani, T
Enterotoxigenic Escherichia coli grown in the presence of lincomycin and tetracycline produced an increased amount of heat-labile enterotoxin (LT). These antibiotics increased the production of not...
Takeda, Y, Honda, T, Sima, H, Tsuji, T, Miwatani, T
Antigenic determinants of cholera enterotoxin (CT) and heat-labile enterotoxin from a human strain (LTh) and a porcine strain (LTp) were analyzed by Ouchterlony double-gel diffusion test against...
Enzyme-linked immunosorbent assay to detect Shiga toxin of Shigella dysenteriae and related toxins.
Kongmuang, U, Honda, T, Miwatani, T
A sandwich enzyme-linked immunosorbent assay (ELISA) was developed for detection of Shiga toxin. Four species of Shigella, Escherichia coli, and Vibro parahaemolyticus were tested for production of...
Nishibuchi, M, Arita, M, Honda, T, Miwatani, T
A commercially available, alkaline-phosphatase-conjugated oligonucleotide probe for detecting the heat-stable enterotoxin gene of Escherichia coli was compared with cloned gene probes by examining E....
Nishibuchi, M, Murakami, A, Arita, M, Jikuya, H, Takano, J, Honda, T, ...
We examined variations in the genes encoding heat-stable enterotoxin (ST) and heat-labile enterotoxin (LT) in 88 strains of Escherichia coli isolated from individuals with traveler's diarrhea to find...
Honda, T, Yoh, M, Kongmuang, U, Miwatani, T
Several systems for enzyme-linked immunosorbent assay (ELISA) of thermostable direct hemolysin (TDH) of Vibrio parahaemolyticus were tested, and single-antibody sandwich ELISA systems gave...
Yoh, M, Narita, I, Honda, T, Miwatani, T, Nishibuchi, M
Ten strains of enterotoxigenic Escherichia coli producing heat-labile enterotoxin (LT) were preserved under 12 different conditions. After 1 month, 9 months, and 3 years of preservation, the cultures...
Honda, T, Sato, M, Miwatani, T
Enzyme-linked immunosorbent assays (ELISAs) with antibodies specific to either cholera enterotoxin (CT) of Vibrio cholerae or heat-labile enterotoxin (LT) of enterotoxigenic Escherichia coli were...
Honda, T, Arita, M, Takeda, Y, Miwatani, T
A total of 2,229 strains of Escherichia coli isolated from subjects with traveller's diarrhea were tested for heat-labile enterotoxin production by the Biken test (Honda et al., J. Clin. Microbiol....
Honda, T, Sornchai, C, Takeda, Y, Miwatani, T
Selective media for Vibrio parahaemolyticus, BTB-Teepol agar and modified arabinose-ammonium sulfate-cholate agar, were modified for use in immunological detection of the thermostable direct...
Honda, T, Samakoses, R, Sornchai, C, Takeda, Y, Miwatani, T
For detection of heat-labile enterotoxin-producing enterotoxigenic Escherichia coli, the staphylococcal coagglutination test reported by Brill et al. (J. Clin. Microbiol. 9:49-55, 1979) was modified...
Immunological methods for detection of Kanagawa phenomenon of Vibrio parahaemolyticus.
Honda, T, Chearskul, S, Takeda, Y, Miwatani, T
A modified Elek test and an immuno-halo test were developed for detection of the thermostable direct hemolysin produced by Kanagawa phenomenon-positive strains of Vibrio parahaemolyticus. The...
Modified Elek test for detection of heat-labile enterotoxin of enterotoxigenic Escherichia coli.
Honda, T, Taga, S, Takeda, Y, Miwatani, T
The Elek test was modified for detection of the heat-labile enterotoxin of enterotoxigenic Escherichia coli. A total of 164 strains of E. coli were tested by the modified Elek test, and the results...
Tang, G Q, Iida, T, Yamamoto, K, Honda, T
A mutant toxin, R7, of thermostable direct hemolysin (TDH) with a single amino acid substitution at glycine 62 was analyzed. The hemolytic activity of R7 decreased to less than 1/1,000 of that of...
Miyake, M, Honda, T, Miwatani, T
Divalent cations and polysaccharides such as inulin and dextran reversibly inhibited hemolysis of rabbit erythrocytes caused by Vibrio metschnikovii cytolysin. On the basis of the 50% inhibitory...
Nishibuchi, M, Taniguchi, T, Misawa, T, Khaeomanee-Iam, V, Honda, T, Miwatani, T
Vibrio parahaemolyticus isolates derived from an outbreak of gastroenteritis in the Republic of Maldives did not have the genetic potential to produce the thermostable direct hemolysin, but one such...
Honda, T, Lertpocasombat, K, Hata, A, Miwatani, T, Finkelstein, R A
A protease produced by a clinical isolate of Vibrio cholerae non-O1 was purified to apparent homogeneity by ammonium sulfate fractionation and successive column chromatography on DEAE-Sephadex A25,...
Yamamoto, K, Ichinose, Y, Shinagawa, H, Makino, K, Nakata, A, Iwanaga, M, ...
Vibrio cholerae O1 biotype El Tor produces and secretes a 65-kDa cytolysin/hemolysin into the culture medium. We cloned the structural gene (hlyA) for the cytolysin from the total DNA of a V....
Tsuji, T, Taga, S, Honda, T, Takeda, Y, Miwatani, T
The heat-labile enterotoxins produced by human enterotoxigenic Escherichia coli (LTh) and porcine enterotoxigenic E. coli (LTp) were purified to homogeneity, and their molecular properties were...
Honda, T, Takeda, Y, Miwatani, T
Cholera enterotoxin (CT) and heat-labile enterotoxin (LT) produced by enterotoxigenic Escherichia coli share a common antigenic determinant. In addition, CT and LT each have a unique antigenic...
Honda, T, Tsuji, T, Takeda, Y, Miwatani, T
The Ouchterlony double-gel diffusion test demonstrated that heat-labile enterotoxin (LT) from human strains of enterotoxigenic Escherichia coli was antigenically related but not identical to that...
Takeda, Y, Honda, T, Taga, S, Miwatani, T
Heat-labile enterotoxin (LT) was purified from cells of enterotoxigenic Escherichia coli isolated from a patient with traveller's diarrhea. Purified LT was separated into A and B subunits by...
Takeda, T, Honda, T, Takeda, Y, Miwatani, T
We studied the effect of chlorpromazine on fluid accumulation caused by purified heat-stable enterotoxin (ST) from enterotoxigenic Escherichia coli in suckling mice. We found that chlorpromazine...
After mutagenesis with nitrosoguanidine and selection by immuno-halo techniques, an avirulent mutant, designated Texas Star-SR, which produces no detectable A (active; ADP-ribosylating) region of the...
A thermolabile direct hemolysin from an El Tor cholera vibrio strain has been isolated and partially characterized as a simple protein of ca. 20,000 molecular weight. In addition to its hemolytic...
Takeda, R, Honda, T, Sakural, J, Otomo, N
The hemolytic activity of the thermostable direct hemolysin produced by Vibrio parahaemolyticus was inhibited by a ganglioside mixture. The ganglioside component which inhibited the hemolysin was not...
Honda, T, Shimizu, M, Takeda, Y, Miwatani, T
A factor changing Chinese hamster ovary cells from an oval to a spindle shape was isolated from the culture filtrate of Vibrio parahaemolyticus. It was partially purified by successive column...
Honda, T, Taga, S, Takeda, T, Hasibuan, M A, Takeda, Y, Miwatani, T
Lethal toxin was purified extensively from the culture filtrate of a Kanagawa phenomenon-positive strain of Vibrio parahaemolyticus. The purified toxin was a protein, and its homogeneity was...
Honda, T, Goshima, K, Takeda, Y, Sugino, Y, Miwatani, T
Intravenous injection of the thermostable direct hemolysin (lethal toxin) produced by Vibrio parahaemolyticus caused rapid death of rats. Studies by electroencephalography and electrocardiography...
Sakurai, J, Honda, T, Jinguji, Y, Arita, M, Miwatani, T
The thermostable direct hemolysin produced by Vibrio parahaemolyticus showed cytotoxic activity on FL cells derived from human amniotic membrane. Scanning electron micrographs of the whole cells...
Takeda, Y, Takeda, T, Honda, T, Miwatani, T
Biological activities of the thermostable direct hemolysin produced by Vibrio parahaemolyticus, such as its hemolytic activity and lethal activity, were inhibited by neuraminidase-sensitive...
Endoscopic treatment of early oesophageal or gastric cancer.
Takeshita, K, Tani, M, Inoue, H, Saeki, I, Hayashi, S, Honda, T, ...
BACKGROUND AND AIMS: Endoscopic treatment has become increasingly popular in recent years as an alternative to surgical treatment with the hope of offering superior quality of life (QOL) for the...
Liver dysfunction among workers handling 5-nitro-o-toluidine
Shimizu, H, Kumada, T, Nakano, S, Kiriyama, S, Sone, Y, Honda, T, ...
Background: 5-Nitro-o-toluidine is an aromatic nitro amino compound. While other aromatic compounds are known to damage the human liver and are registered as toxic substances, toxicity information...
Effect of periodontal treatment on the serum antibody levels to heat shock proteins
YAMAZAKI, K, UEKI-MARUAYAMA, K, HONDA, T, NAKAJIMA, T, SEYMOUR, G J
We have shown previously that both humoral and cellular immune responses to heat shock protein 60 (HSP60) are elevated in chronic periodontitis patients compared with non-diseased subjects. The aim...
Balance of inflammatory response in stable gingivitis and progressive periodontitis lesions
Honda, T, Domon, H, Okui, T, Kajita, K, Amanuma, R, Yamazaki, K
The balance between inflammatory mediators and their counter-regulatory molecules may be crucial for determining the outcome of immune pathology of periodontal diseases. Based on clinical and...
Sakaue, S., Nishihira, J., Hirokawa, J., Yoshimura, H., Honda, T., Aoki, K., ...
BACKGROUND: It has been reported that macrophage migration inhibitory factor (MIF) stimulated insulin secretion from pancreatic islet beta-cells in an autocrine manner, which suggests its pivotal...
Kubo, K., Hanaoka, M., Yamaguchi, S., Hayano, T., Hayasaka, M., Koizumi, T., ...
BACKGROUND: The precise mechanism of high altitude pulmonary oedema (HAPE) remains unclear. The purpose of this study was to evaluate the role of cytokines and P-selectin in the development of HAPE...
Bronchoalveolar lavage fluid findings in patients with chronic hepatitis C virus infection.
Kubo, K, Yamaguchi, S, Fujimoto, K, Hanaoka, M, Hayasaka, M, Honda, T, ...
BACKGROUND: Hepatitis C virus (HCV) infection has recently been incriminated as an aetiological agent in idiopathic pulmonary fibrosis. This study was performed to determine the cellularity and...
Yamaguchi, S., Kubo, K., Fujimoto, K., Honda, T., Sekiguchi, M., Sodeyama, T.
BACKGROUND: Previous studies have shown that patients with idiopathic pulmonary fibrosis (IPF) were more likely to be seropositive for hepatitis C virus (HCV) than normal controls, and that patients...
Results of Endoscopic Treatment for Early Gastric Cancer by Nd-YAG Laser
Tani, M., Takeshita, K., Honda, T., Saito, N., Endo, M.
We have introduced two endoscopic treatments for early gastric cancer: endoscopic mucosal resection using a cap-fitted panendoscope (EMRC), and endoscopic laser therapy using a Nd-YAG laser....
Yamazaki, K, Honda, T, Domon, H, Okui, T, Kajita, K, Amanuma, R, ...
Several reports have demonstrated a possible association of periodontal infections with coronary heart disease (CHD) by elevated antibody titre to periodontopathic bacteria in CHD patients compared...
Sang, W. K., Oundo, J. O., Mwituria, J. K., Waiyaki, P. G., Yoh, M., Iida, T., ...
To study the association of multidrug-resistant enteroaggregative Escherichia coli with persistent diarrhea in Kenyan children, stool specimens were obtained from 862 outpatients under 5 years of age...
Filamentous phage associated with recent pandemic strains of Vibrio parahaemolyticus.
Iida, T., Hattori, A., Tagomori, K., Nasu, H., Naim, R., Honda, T.
A group of pandemic strains of Vibrio parahaemolyticus has recently appeared in Asia and North America. We demonstrate that a filamentous phage is specifically associated with the pandemic V....
Resistance to dryness of Escherichia coli O157:H7 strains from outbreak in Sakai City, Japan, 1996.
Iijima, Y., Matsumoto, M., Higuchi, K., Furuta, T., Honda, T.
RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
Endoh, M, Tamura, G, Honda, T, Homma, N, Terashima, M, Nishizuka, S, ...
RASSF2, a member of the RASSF1 family, has recently been identified as a potential tumour suppressor. We examined methylation status in multiple regions which included the CpG island and spanned the...
Uchino, H, Matsumura, Y, Negishi, T, Koizumi, F, Hayashi, T, Honda, T, ...
In spite of the clinical usefulness of cisplatin (CDDP), there are many occasions in which it is difficult to continue the administration of CDDP due to its nephrotoxicity and neurotoxicity. We...
Sone, S, Li, F, Yang, Z-G, Honda, T, Maruyama, Y, Takashima, S, ...
The aim of this study was to evaluate the usefulness of annual screening for lung cancer by low-dose computed tomography (CT) and the characteristics of identified lung cancers. Subjects consisted of...