Influence of moving to the UK on maternal health behaviours: prospective cohort study (2008)
Hawkins, S.S., Lamb, K., Cole, T.J., Law, C.
OBJECTIVE: To compare health behaviours during pregnancy (smoking and alcohol consumption) and after birth (initiation and duration of breast feeding) between British/Irish white mothers and mothers...
Pearce, A., Law, C., Elliman, D., Cole, T.J., Bedford, H.
Objectives: To estimate uptake of the combined measles, mumps, and rubella vaccine (MMR) and single antigen vaccines and explore factors associated with uptake and reasons for not using MMR. Design:...
Body shape in American and British adults: between-country and inter-ethnic comparisons (2008)
Wells, J.C.K., Cole, T.J., Bruner, D., Treleaven, P.
Background: Recent studies indicate differences between British and American white adults, and between income and ethnic groups within the United States, in the population distribution of lifestyle...
Cole, T.J., Stanojevic, S., Stocks, J., Coates, A.L., Hankinson, J.L., Wade, A.M.
Summary: Age-related reference ranges are useful for assessing growth in children. The LMS method is a popular technique for constructing growth charts that model the age-changing distribution of the...
Body mass index cut offs to define thinness in children and adolescents: international survey (2007)
Cole, T.J., Flegal, K.M., Nicholls, D., Jackson, A.A.
Objective: To determine cut offs to define thinness in children and adolescents, based on body mass index at age 18 years. Design International survey of six large nationally representative cross...
BMI compared with 3-dimensional body shape: the UK National Sizing Survey (2007)
Wells, J.C.K., Treleaven, P., Cole, T.J.
Background: Human body shape is a rich source of information about health and the risk of disease. Measuring anthropometry manually is time-consuming, however, and only a few indexes of shape (eg,...
Singhal, A., Cole, T.J., Fewtrell, M., Kennedy, K., Stephenson, T., Elias-Jones, A., ...
Background: Being born small for gestational age is associated with later risk factors for cardiovascular disease, such as high blood pressure. Promotion of postnatal growth has been proposed to...
Cole, T.J., Cortina-Borja, M., Sandhu, J., Kelly, F.P., Pan, H.
Higher moments of the frequency distribution of child height and weight change with age, particularly during puberty, though why is not known. Our aims were to confirm that height skewness and...
Wardle, J., Brodersen, N.H., Cole, T.J., Jarvis, M.J., Boniface, D.R.
Objective: To examine the developmental trajectory of obesity in adolescence in relation to sex, ethnicity, and socioeconomic status. Design: Five year longitudinal cohort study of a...
Fewtrell, M.S., Gordon, I., Biassoni, L., Cole, T.J.
Dual X-ray absorptiometry (DXA) is increasingly used in a clinical setting to evaluate bone mass in children. Areal Bone Mineral Density (aBMD) measurements are known to be influenced by body size,...
Calcium supplementation increases stature and bone mineral mass of 16- to 18-year-old boys (2005)
Prentice, A., Ginty, F., Stear, S.J., Jones, S.C., Laskey, M.A., Cole, T.J.
The effect of calcium carbonate supplementation on bone growth and mineral accretion was studied in 143 boys aged 16–18 yr, randomized to 1000 mg Ca/d or a matching placebo for 13 months....
Objectives: To assess adult socioeconomic, educational, social, and psychological outcomes of childhood obesity by using nationally representative data. Design: 1970 British birth cohort....
Cole, T.J., Altman, D., Ashby, D., Campbell, M., Deeks, J., Evans, S., ...
Prematurity and reduced body fatness at 8–12 y of age (2004)
Fewtrell, M.S., Lucas, A., Cole, T.J., Wells, J.C.K.
Background: Increasing evidence suggests that body composition, an important factor influencing morbidity and mortality in adult life, might be programmed by early growth and nutrition. Children born...
Singhal, A., Cole, T.J., Fewtrell, M., Lucas, A.
Background: Breastfeeding is associated with reduced cholesterol concentration later in life, but previous studies have not used random assignment of infant diet with prospective follow-up. We tested...
Is slower early growth beneficial for long-term cardiovascular health? (2004)
Singhal, A., Cole, T.J., Fewtrell, M., Deanfield, J., Lucas, A.
Background: Accelerated neonatal growth increases the later propensity to cardiovascular disease (CVD) in animals, whereas slower growth is thought to have a beneficial effect. To test this...
Children grow and horses race: is the adiposity rebound a critical period for later obesity? (2004)
BACKGROUND: The adiposity rebound is the second rise in body mass index that occurs between 3 and 7 years. An early age at adiposity rebound is known to be a risk factor for later obesity. The aim...
T. J. Cole, M. S. Ram, F. E. Dowell, C. O. Omwega, W. A. Overholt, S. B. Ramaswamy
Parasitoids of the Cotesia flavipes complex (C. flavipes and Cotesia sesamiae) are natural enemies of stemboring lepidopteran pests in sub-Saharan Africa. The two species are difficult to...
M. E. Rogers, T. J. Cole, S. B. Ramaswamy, D. A. Potter
We studied effects of parasitism by two Tiphia species (Hymenoptera: Tiphiidae) on burrowing behavior of their respective scarabaeid hosts and tested the hypothesis that parasitoid alteration of host...
Low nutrient intake and early growth for later insulin resistance in adolescents born preterm (2003)
Singhal, A., Fewtrell, M., Cole, T.J., Lucas, A.
Background: In animals, acceleration of neonatal growth is thought to increase the later propensity to insulin resistance and non-insulin-dependent diabetes, whereas slow growth as a consequence of...
Singhal, A., Wells, J., Cole, T.J., Fewtrell, M., Lucas, A.
Background: A high birth weight has been suggested to increase the later risk of obesity, as measured by body mass index, but, paradoxically, to decrease the later propensity to cardiovascular...
Gordon, I., Barkovics, M., Pindoria, S., Cole, T.J., Woolf, A.S.
Renal parenchymal disease after urinary tract infection (UTI) has been associated with the development of hypertension and renal functional impairment. A systematic literature review and...
Wells, J.C.K., Treleaven, P., Cole, T.J.
Objective: To assess the association between duration of breast feeding and measures of adiposity in adolescence. Design: Population based birth cohort study. Setting: Pelotas, a city of 320 000...
McCarthy, H.D., Ellis, S.M., Cole, T.J.
Objective: To compare changes over time in waist circumference (a measure of central fatness) and body mass index (a measure of overall obesity) in British youth. Design: Representative cross...
Singhal, A., Farooqi, I.S., Cole, T.J., O’Rahilly, S., Fewtrell, M., Kattenhorn, M., ...
Background: The mechanisms by which obesity increases the risk of atherosclerotic cardiovascular disease (CVD) are poorly understood. In experimental models, leptin, a hormone produced by adipose...
Leeson, C.P.M., Hingorani, S.D., Mullen, M.J., Jeerooburkhan, N., Kattenhorn, M., Cole, T.J., ...
An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has been associated with cardiovascular disease. We investigated whether carriage of the polymorphism was associated with...
Sex-specific prediction equations for VmaxFRC in infancy: a multicenter collaborative study (2002)
Dezateux, C., Hanrahan, J.P., Cole, T.J., Tepper, R.S., Stocks, J.
Measurements of maximal flow at functional residual capacity (Vmax FRC) from partial forced expiratory maneuvers remain the most popular method for assessing small airway function in infants and...
Singhal, A., Cole, T.J., Lucas, A.
Background: Despite data relating body size in early life to later cardiovascular outcomes, the hypothesis that nutrition affects such outcomes has not been established. Breastfeeding has been...
Cole, T.J., Bellizzi, M.C., Flegal, K.M., Dietz, W.H.
Objective: To develop an internationally acceptable definition of child overweight and obesity, specifying the measurement, the reference population, and the age and sex specific cut off points....
Fetal origins of adult disease-the hypothesis revisited (1999)
Lucas, A., Fewtrell, M.S., Cole, T.J.
The idea that stimuli or insults during critical or sensi tive periods in early life can have lifetime consequences is well established in developmental biology and has been termed...
Sas, T.C., Gerver, W.J., Bruin, R. De, Stijnen, T., Cole, T.J., ...
To assess body proportions in girls with Turner syndrome (TS) during long term GH treatment, height, sitting height (SH), hand (Hand) and foot (Foot) lengths, and biacromial (Biac) and biiliacal...
Randomised trial of early diet in preterm babies and later intelligence quotient (1998)
Lucas, A., Morley, R., Cole, T.J.
Objectives: To determine whether perinatal nutrition influences cognitive function at 7 1/2 - 8 years in children born preterm. Design: Randomised, blinded nutritional intervention trial. Blinded...
Ceesay, S.M., Prentice, A.M., Cole, T.J., Foord, F., Poskitt, E.M.E., Weaver, L.T., ...
Objective: To test the efficacy in terms of birth weight and infant survival of a diet supplement programme in pregnant African women through a primary healthcare system. Design: 5 year controlled...
Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption (1997)
Oitzl, M.S., De Kloet, R., Joels, M., Schmid, W., Cole, T.J.
Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption (1997)
Oitzl, M.S., Meijer, O.C., Joels, M., Cole, T.J., Schmid, W., De Kloet, R.
Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption (1997)
Oitzl, M.S., Meijer, O.C., Joels, M., Cole, T.J., Schmid, W., Schutz, G., ...
Properties of hippocampal CA1 neurons in glucocorticoid receptor knockout mice (1996)
Hesen, W.S., Karst, H., Cole, T.J., Schmid, W., De Kloet, R., Joels, M.
Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption (1996)
Hesen, W.S., Karst, H., Meijer, O, Cole, T.J., Schmidt, W., De Kloet, R., ...
Do growth chart centiles need a face lift? (1994)
European height and weight growth charts commonly extend from the 3rd to the 97th centile, whereas in North America the extremes are usually the 5th and 95th centiles. There is no good reason for the...
Hummler, E., Cole, T. J., Blendy, J. A., Ganss, R., Aguzzi, A., Schmid, W., ...
The cAMP response element binding protein (CREB) has been implicated as a key regulator in the transcriptional control of many genes. To assess the functional importance of CREB in vivo and its role...
Lucas, A., Brooke, O.G., Morley, R., Cole, T.J., Bamford, M.F.
OBJECTIVE--To study the effect of early diet on the development of allergic reactions in infants born preterm. DESIGN--Two randomised prospective trails. In trail A infants were randomly allocated...
Adverse neurodevelopmental outcome of moderate neonatal hypoglycaemia (1988)
Lucas, A., Morley, R., Cole, T.J.
There has been considerable debate over whether asymptomatic neonatal hypoglycaemia results in neurological damage. In a detailed multicentre study of 661 preterm infants hypoglycaemia was found to...
Maternal fatness and viability of preterm infants (1988)
Lucas, A., Morley, R., Cole, T.J., Bamford, M.F., Boon, A., Crowle, P., ...
To investigate the effect of maternal fatness on the mortality of infants born preterm up to the corrected age of 18 months 795 mother-infant pairs were studied. Maternal fatness was defined by...
Ashwell, M., Cole, T.J., Dixon, A.K.
Twenty eight women presenting for routine computed tomography had their waist, hip, and thigh circumferences measured. The ratio of the area of intra-abdominal fat to the area of subcutaneous fat...
Viegas, O.A., Scott, P.H., Cole, T.J., Mansfield, H.N., Wharton, P., Wharton, B.A.
At Sorrento Maternity Hospital Asian mothers whose babies had grown poorly in utero had anthropometric and biochemical evidence suggesting an inadequate nutritional state. To test this hypothesis...
Viegas, O.A., Scott, P.H., Cole, T.J., Eaton, P., Needham, P.G., Wharton, B.A.
Unselective dietary protein energy supplementation of Asian mothers at Sorrento Maternity Hospital did not enhance intrauterine growth. The effect of selective supplementation was therefore studied....
Relative contributions of diet and sunlight to vitamin D state in the elderly (1979)
Lawson, D.E., Mandal, T., Paul, A.A., Black, A.E., Cole, T.J., Davie, M.
In winter the vitamin D state of elderly people may reach levels associated with osteomalacia, although the disease may not be clinically apparent. A statistical correlation was observed in a group...
Diet, sunlight, and 25-hydroxy vitamin D in healthy children and adults (1979)
Poskitt, E.M., Cole, T.J., Lawson, D.E.
In 110 white West Midlands children serum 25-hydroxy vitamin D (25-OHD) concentrations showed a pronounced seasonal variation, the values being highest in August and lowest in February. The...
Nature, nurture, and childhood overweight (1978)
The relative importance of dietary and familial factors in determining weight in early infancy were studied in 203 5-year-old children. Their age at weaning, energy intake in infancy and at 5 years,...
Do fat babies stay fat? (1977)
A total of 203 children included in a study of feeding practices and weight in infancy were reviewed four to five years later. Although in infancy 28 (14%) of the children were obese and a further 52...
Montoliu, L, Blendy, J A, Cole, T J, Schütz, G
The transcription of genes encoding gluconeogenic enzymes is tightly regulated during the perinatal period. These genes are induced by glucagon (cAMP) and glucocorticoids and repressed by insulin. To...
Hummler, E, Cole, T J, Blendy, J A, Ganss, R, Aguzzi, A, Schmid, W, ...
The cAMP response element binding protein (CREB) has been implicated as a key regulator in the transcriptional control of many genes. To assess the functional importance of CREB in vivo and its role...
At least three promoters direct expression of the mouse glucocorticoid receptor gene.
Strähle, U, Schmidt, A, Kelsey, G, Stewart, A F, Cole, T J, Schmid, W, ...
We have characterized the gene for the mouse glucocorticoid receptor. The gene spans approximately 110 kilobases, and glucocorticoid receptor transcripts are assembled from nine exons. Expression of...
Ruppert, S, Cole, T J, Boshart, M, Schmid, E, Schütz, G
We have characterized cDNA clones representing mouse CREB (cyclic AMP responsive element binding protein) mRNA isoforms. These include CREB delta and CREB alpha, of which the rat and human homologues...
Ashwell, M, Cole, T J, Dixon, A K
Twenty eight women presenting for routine computed tomography had their waist, hip, and thigh circumferences measured. The ratio of the area of intra-abdominal fat to the area of subcutaneous fat...