T. J. Nelson

Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20.

Kim, C S, Han, Y F, Etcheberrigaray, R, Nelson, T J, Olds, J L, Yoshioka, T, ...

The two proteins most consistently identified in the brains of patients with Alzheimer disease (AD) have been beta-amyloid and tau, whose roles in the physiology or pathophysiology of brain cells are...

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease.

Ito, E, Oka, K, Etcheberrigaray, R, Nelson, T J, McPhie, D L, Tofel-Grehl, B, ...

The recent demonstration of K+ channel dysfunction in fibroblasts from Alzheimer disease (AD) patients and past observations of Ca(2+)-mediated K+ channel modulation during memory storage suggested...

Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport.

Nelson, T J, Yoshioka, T, Toyoshima, S, Han, Y F, Alkon, D L

The phosphorylation state of cp20, a low molecular weight GTP-binding protein that is a high-affinity substrate for protein kinase C, was previously shown to change after associative conditioning of...

Specific high molecular weight mRNAs induced by associative learning in Hermissenda.

Nelson, T J, Alkon, D L

Associative conditioning of Hermissenda crassicornis has been demonstrated to result in long-term changes in the potassium currents IA and ICa2(+)-K+ in photoreceptor neurons in the eye and to...

Prolonged RNA changes in the Hermissenda eye induced by classical conditioning.

Nelson, T J, Alkon, D L

The incorporation of 32P into mRNA and the total amount of mRNA were increased 3- to 4-fold in eyes isolated from Hermissenda crassicornis trained to associate light with rotation on a turntable...

In vivo-like drug responses of human tumors growing in three-dimensional gel-supported primary culture.

Vescio, R A, Redfern, C H, Nelson, T J, Ugoretz, S, Stern, P H, Hoffman, R M

An in vitro test of cell sensitivity to drugs that indicates in vivo response is an important need in cancer therapy and cancer drug development. Toward this end, we previously developed a collagen...

Calexcitin interaction with neuronal ryanodine receptors.

Nelson, T J, Zhao, W Q, Yuan, S, Favit, A, Pozzo-Miller, L, Alkon, D L

Calexcitin (CE), a Ca2+- and GTP-binding protein, which is phosphorylated during memory consolidation, is shown here to co-purify with ryanodine receptors (RyRs) and bind to RyRs in a...

Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20.

Kim, C S, Han, Y F, Etcheberrigaray, R, Nelson, T J, Olds, J L, Yoshioka, T, ...

The two proteins most consistently identified in the brains of patients with Alzheimer disease (AD) have been beta-amyloid and tau, whose roles in the physiology or pathophysiology of brain cells are...

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease.

Ito, E, Oka, K, Etcheberrigaray, R, Nelson, T J, McPhie, D L, Tofel-Grehl, B, ...

The recent demonstration of K+ channel dysfunction in fibroblasts from Alzheimer disease (AD) patients and past observations of Ca(2+)-mediated K+ channel modulation during memory storage suggested...

Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport.

Nelson, T J, Yoshioka, T, Toyoshima, S, Han, Y F, Alkon, D L

The phosphorylation state of cp20, a low molecular weight GTP-binding protein that is a high-affinity substrate for protein kinase C, was previously shown to change after associative conditioning of...

Specific high molecular weight mRNAs induced by associative learning in Hermissenda.

Nelson, T J, Alkon, D L

Associative conditioning of Hermissenda crassicornis has been demonstrated to result in long-term changes in the potassium currents IA and ICa2(+)-K+ in photoreceptor neurons in the eye and to...

Prolonged RNA changes in the Hermissenda eye induced by classical conditioning.

Nelson, T J, Alkon, D L

The incorporation of 32P into mRNA and the total amount of mRNA were increased 3- to 4-fold in eyes isolated from Hermissenda crassicornis trained to associate light with rotation on a turntable...

In vivo-like drug responses of human tumors growing in three-dimensional gel-supported primary culture.

Vescio, R A, Redfern, C H, Nelson, T J, Ugoretz, S, Stern, P H, Hoffman, R M

An in vitro test of cell sensitivity to drugs that indicates in vivo response is an important need in cancer therapy and cancer drug development. Toward this end, we previously developed a collagen...

Calexcitin interaction with neuronal ryanodine receptors.

Nelson, T J, Zhao, W Q, Yuan, S, Favit, A, Pozzo-Miller, L, Alkon, D L

Calexcitin (CE), a Ca2+- and GTP-binding protein, which is phosphorylated during memory consolidation, is shown here to co-purify with ryanodine receptors (RyRs) and bind to RyRs in a...