T. J. Triche

Olfactory neuroblastoma is a peripheral primitive neuroectodermal tumor related to Ewing sarcoma.

Sorensen, P H, Wu, J K, Berean, K W, Lim, J F, Donn, W, Frierson, H F, ...

Olfactory neuroblastoma (ONB) is a malignant tumor of the nasal mucosa whose histogenesis is unclear. A relationship to neuroblastoma (NB), a pediatric tumor of the sympathetic nervous system, is...

Homozygous hypobetalipoproteinemia: a disease distinct from abetalipoproproteinemia at the molecular level.

Ross, R S, Gregg, R E, Law, S W, Monge, J C, Grant, S M, Higuchi, K, ...

apoB DNA, RNA, and protein from two patients with homozygous hypobetalipoproteinemia (HBL) were evaluated and compared with normal individuals. Southern blot analysis with 10 different cDNA probes...

Induction of plasmacytoid differentiation by phorbol ester in B-cell lymphoma cell lines bearing 8;14 translocations.

Benjamin, D, Magrath, I T, Triche, T J, Schroff, R W, Jensen, J P, Korsmeyer, S J

At nanomolar concentrations, phorbol 12-myristate 13-acetate induced differentiation in a human Epstein-Barr virus-negative B-cell line, JD 38, derived from an undifferentiated lymphoma and...

Cystine accumulation and clearance by normal and cystinotic leukocytes exposed to cystine dimethyl ester.

Steinherz, R, Tietze, F, Gahl, W A, Triche, T J, Chiang, H, Modesti, A, ...

Upon exposure to 0.25 mM cystine dimethyl ester, normal and cystinotic leukocytes accumulate substantially more intracellular cystine than is present endogenously in cystinotic cells. Leukocytes...

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

Zucman, J, Melot, T, Desmaze, C, Ghysdael, J, Plougastel, B, Peter, M, ...

Balanced translocations involving band q12 of human chromosome 22 are the most frequent recurrent translocations observed in human solid tumours. It has been shown recently that this region encodes...

Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia.

Lackner, K J, Monge, J C, Gregg, R E, Hoeg, J M, Triche, T J, Law, S W, ...

The apolipoprotein B-100 (apoB-100) gene in leukocytes and the apoB-100 messenger RNA (mRNA) and translated apolipoprotein in the livers from normal and abetalipoproteinemic individuals were...

Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system.

Thiele, C J, McKeon, C, Triche, T J, Ross, R A, Reynolds, C P, Israel, M A

We have found highly predictable patterns of protooncogene expression in cell lines and tumor tissue of neuroblastoma (NB), a tumor of the peripheral nervous system (PNS). These patterns make it...

Olfactory neuroblastoma is a peripheral primitive neuroectodermal tumor related to Ewing sarcoma.

Sorensen, P H, Wu, J K, Berean, K W, Lim, J F, Donn, W, Frierson, H F, ...

Olfactory neuroblastoma (ONB) is a malignant tumor of the nasal mucosa whose histogenesis is unclear. A relationship to neuroblastoma (NB), a pediatric tumor of the sympathetic nervous system, is...

Homozygous hypobetalipoproteinemia: a disease distinct from abetalipoproproteinemia at the molecular level.

Ross, R S, Gregg, R E, Law, S W, Monge, J C, Grant, S M, Higuchi, K, ...

apoB DNA, RNA, and protein from two patients with homozygous hypobetalipoproteinemia (HBL) were evaluated and compared with normal individuals. Southern blot analysis with 10 different cDNA probes...

Induction of plasmacytoid differentiation by phorbol ester in B-cell lymphoma cell lines bearing 8;14 translocations.

Benjamin, D, Magrath, I T, Triche, T J, Schroff, R W, Jensen, J P, Korsmeyer, S J

At nanomolar concentrations, phorbol 12-myristate 13-acetate induced differentiation in a human Epstein-Barr virus-negative B-cell line, JD 38, derived from an undifferentiated lymphoma and...

Cystine accumulation and clearance by normal and cystinotic leukocytes exposed to cystine dimethyl ester.

Steinherz, R, Tietze, F, Gahl, W A, Triche, T J, Chiang, H, Modesti, A, ...

Upon exposure to 0.25 mM cystine dimethyl ester, normal and cystinotic leukocytes accumulate substantially more intracellular cystine than is present endogenously in cystinotic cells. Leukocytes...

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

Zucman, J, Melot, T, Desmaze, C, Ghysdael, J, Plougastel, B, Peter, M, ...

Balanced translocations involving band q12 of human chromosome 22 are the most frequent recurrent translocations observed in human solid tumours. It has been shown recently that this region encodes...

Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia.

Lackner, K J, Monge, J C, Gregg, R E, Hoeg, J M, Triche, T J, Law, S W, ...

The apolipoprotein B-100 (apoB-100) gene in leukocytes and the apoB-100 messenger RNA (mRNA) and translated apolipoprotein in the livers from normal and abetalipoproteinemic individuals were...

Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system.

Thiele, C J, McKeon, C, Triche, T J, Ross, R A, Reynolds, C P, Israel, M A

We have found highly predictable patterns of protooncogene expression in cell lines and tumor tissue of neuroblastoma (NB), a tumor of the peripheral nervous system (PNS). These patterns make it...

An immunohistochemical study of pi class glutathione S-transferase expression in normal human tissue.

Terrier, P., Townsend, A. J., Coindre, J. M., Triche, T. J., Cowan, K. H.

Glutathione S-transferases (GSTs), a family of isoenzymes that play an important role in protecting cells from cytotoxic and carcinogenic agents, can be separated by biochemical and immunologic...

Detection of N-myc gene expression in neuroblastoma tumors by in situ hybridization.

Cohen, P. S., Seeger, R. C., Triche, T. J., Israel, M. A.

The presence of N-myc DNA amplification in human neuroblastoma tumors has been shown to be an independent prognostic factor predicting rapid progression of disease. Southern blot analysis has been...

Immunohistochemical analysis of Ewing's sarcoma cell surface antigen p30/32MIC2.

Fellinger, E. J., Garin-Chesa, P., Triche, T. J., Huvos, A. G., Rettig, W. J.

Monoclonal antibody (MAb) HBA71, which was raised against Ewing's sarcoma cells, recognizes a cell-surface glycoprotein, p30/32MIC2, that is encoded by the MIC2 gene in the pseudoautosomal region of...

Immunohistochemical analysis of neural cell adhesion molecules. Differential expression in small round cell tumors of childhood and adolescence.

Garin-Chesa, P., Fellinger, E. J., Huvos, A. G., Beresford, H. R., Melamed, M. R., Triche, T. J., ...

The neural cell adhesion molecule (NCAM) was discovered in a search for cell surface antigens of chicken neurons that contribute to cell adhesion and pattern formation during development. Homologous...

Differentiation of human retinoblastoma in vitro into cell types with characteristics observed in embryonal or mature retina.

Tsokos, M., Kyritsis, A. P., Chader, G. J., Triche, T. J.

The capacity of a primitive human retinoblastoma cell line (Y-79) to differentiate into several cell types of normal human retina was investigated. Cells were studied in suspension and monolayer...

Differentiation of human neuroblastoma recapitulates neural crest development. Study of morphology, neurotransmitter enzymes, and extracellular matrix proteins.

Tsokos, M., Scarpa, S., Ross, R. A., Triche, T. J.

Differentiation of human neuroblastoma (NB) was studied in vitro with five NB cell lines treated with dibutyryl cyclic adenosinemonophosphate and retinoic acid. Although the above agents induced...

Extracellular matrix synthesis by undifferentiated childhood tumor cell lines.

Scarpa, S., Modesti, A., Triche, T. J.

The authors have examined extracellular matrix (ECM) biosynthesis by small round cell tumors of childhood. Basal lamina (laminin and Type IV collagen) and stroma (collagens I, III, and V and...

Experimental evidence for a neural origin of Ewing's sarcoma of bone.

Cavazzana, A. O., Miser, J. S., Jefferson, J., Triche, T. J.

The histogenesis of Ewing's sarcoma remains unknown. Recent studies have suggested a relationship to an unusual form of childhood neural tumor, often termed peripheral neuroepithelioma or primitive...