T. J. Tsomides

T-cell antigens in cancer.

Tsomides, T J, Eisen, H N

High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins.

Sykulev, Y, Brunmark, A, Tsomides, T J, Kageyama, S, Jackson, M, Peterson, P A, ...

We report here that the intrinsic affinities of the antigen-specific T-cell receptors (TCR) of two unrelated CD8+ T-cell clones for their respective peptide-major histocompatibility complex (MHC)...

A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone.

Udaka, K, Tsomides, T J, Walden, P, Fukusen, N, Eisen, H N

We previously isolated from mouse spleen an octapeptide (LSPFPFDL) that in association with the class I major histocompatibility complex protein Ld is recognized by the antigen-specific receptor of...

An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein.

Tsomides, T J, Walker, B D, Eisen, H N

CD8+ cytotoxic T lymphocytes recognize cell surface complexes formed by class I major histocompatibility complex (MHC-I) glycoproteins and antigenic peptides. We have identified a peptide nonamer...

T-cell antigens in cancer.

Tsomides, T J, Eisen, H N

High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins.

Sykulev, Y, Brunmark, A, Tsomides, T J, Kageyama, S, Jackson, M, Peterson, P A, ...

We report here that the intrinsic affinities of the antigen-specific T-cell receptors (TCR) of two unrelated CD8+ T-cell clones for their respective peptide-major histocompatibility complex (MHC)...

A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone.

Udaka, K, Tsomides, T J, Walden, P, Fukusen, N, Eisen, H N

We previously isolated from mouse spleen an octapeptide (LSPFPFDL) that in association with the class I major histocompatibility complex protein Ld is recognized by the antigen-specific receptor of...

An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein.

Tsomides, T J, Walker, B D, Eisen, H N

CD8+ cytotoxic T lymphocytes recognize cell surface complexes formed by class I major histocompatibility complex (MHC-I) glycoproteins and antigenic peptides. We have identified a peptide nonamer...