A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-delta 1.
Kanematsu, T, Misumi, Y, Watanabe, Y, Ozaki, S, Koga, T, Iwanaga, S, ...
We have reported that two inositol 1,4,5-trisphosphate binding proteins, with molecular masses of 85 and 130 kDa, were purified from rat brain; the former protein was found to be the delta...
Takeuchi, H, Kanematsu, T, Misumi, Y, Yaakob, H B, Yagisawa, H, Ikehara, Y, ...
We have previously identified a novel 130 kDa protein (p130) which binds Ins(1,4,5)P3 and shares 38% sequence identity with phospholipase C-delta 1 [Kanematsu, Misumi, Watanabe, Ozaki, Koga, Iwanaga,...
PTB domain of insulin receptor substrate-1 binds inositol compounds.
Takeuchi, H, Matsuda, M, Yamamoto, T, Kanematsu, T, Kikkawa, U, Yagisawa, H, ...
We examined whether a phosphotyrosine binding (PTB) domain from the human insulin receptor substrate-1 (hIRS-1) is capable of binding inositol phosphates/phosphoinositides. The binding specificity...
Takeuchi, H, Oike, M, Paterson, H F, Allen, V, Kanematsu, T, Ito, Y, ...
p130 was originally identified as an Ins(1,4,5)P(3)-binding protein similar to phospholipase C-delta but lacking any phospholipase activity. In the present study we have further analysed the...
Motojima, K, Urano, T, Nagata, Y, Shiku, H, Tsurifune, T, Kanematsu, T
It has been reported that multicentricity of pancreatic carcinomas extending beyond the pancreatic duct occur in 15% to 40% of patients. This has been difficult to confirm, however, with currently...
Intraperitoneal septic complications after hepatectomy.
Yanaga, K, Kanematsu, T, Takenaka, K, Sugimachi, K
One hundred forty-nine elective hepatic resections were performed during the 12 years from 1973 to 1984. Nineteen of these patients (12.8%) developed intraperitoneal septic complications after...
Limited hepatic resection effective for selected cirrhotic patients with primary liver cancer.
Kanematsu, T, Takenaka, K, Matsumata, T, Furuta, T, Sugimachi, K, Inokuchi, K
We evaluated in retrospect the applicability of limited hepatic resection in cases of primary liver cancer in cirrhotic patients. According to the severity of impaired liver function, 37 patients...
Motojima, K, Tsunoda, T, Kanematsu, T, Nagata, Y, Urano, T, Shiku, H
The prevalence of Kirsten (Ki)-ras gene mutations was studied in 105 paraffin-embedded tissues obtained from 40 patients with pancreatic cancer, 48 with bile duct carcinoma (19 distal, 6 middle, and...
Yoshida, Y, Kanematsu, T, Matsumata, T, Takenaka, K, Sugimachi, K
This report attempts to elucidate the manner in which the surgical margin is linked to a recurrence after curative hepatectomy for hepatocellular carcinoma (HCC) in patients with cirrhosis. Forty...
A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-delta 1.
Kanematsu, T, Misumi, Y, Watanabe, Y, Ozaki, S, Koga, T, Iwanaga, S, ...
We have reported that two inositol 1,4,5-trisphosphate binding proteins, with molecular masses of 85 and 130 kDa, were purified from rat brain; the former protein was found to be the delta...
Takeuchi, H, Kanematsu, T, Misumi, Y, Yaakob, H B, Yagisawa, H, Ikehara, Y, ...
We have previously identified a novel 130 kDa protein (p130) which binds Ins(1,4,5)P3 and shares 38% sequence identity with phospholipase C-delta 1 [Kanematsu, Misumi, Watanabe, Ozaki, Koga, Iwanaga,...
PTB domain of insulin receptor substrate-1 binds inositol compounds.
Takeuchi, H, Matsuda, M, Yamamoto, T, Kanematsu, T, Kikkawa, U, Yagisawa, H, ...
We examined whether a phosphotyrosine binding (PTB) domain from the human insulin receptor substrate-1 (hIRS-1) is capable of binding inositol phosphates/phosphoinositides. The binding specificity...
Takeuchi, H, Oike, M, Paterson, H F, Allen, V, Kanematsu, T, Ito, Y, ...
p130 was originally identified as an Ins(1,4,5)P(3)-binding protein similar to phospholipase C-delta but lacking any phospholipase activity. In the present study we have further analysed the...
Motojima, K, Urano, T, Nagata, Y, Shiku, H, Tsurifune, T, Kanematsu, T
It has been reported that multicentricity of pancreatic carcinomas extending beyond the pancreatic duct occur in 15% to 40% of patients. This has been difficult to confirm, however, with currently...
Intraperitoneal septic complications after hepatectomy.
Yanaga, K, Kanematsu, T, Takenaka, K, Sugimachi, K
One hundred forty-nine elective hepatic resections were performed during the 12 years from 1973 to 1984. Nineteen of these patients (12.8%) developed intraperitoneal septic complications after...
Limited hepatic resection effective for selected cirrhotic patients with primary liver cancer.
Kanematsu, T, Takenaka, K, Matsumata, T, Furuta, T, Sugimachi, K, Inokuchi, K
We evaluated in retrospect the applicability of limited hepatic resection in cases of primary liver cancer in cirrhotic patients. According to the severity of impaired liver function, 37 patients...
Motojima, K, Tsunoda, T, Kanematsu, T, Nagata, Y, Urano, T, Shiku, H
The prevalence of Kirsten (Ki)-ras gene mutations was studied in 105 paraffin-embedded tissues obtained from 40 patients with pancreatic cancer, 48 with bile duct carcinoma (19 distal, 6 middle, and...
Yoshida, Y, Kanematsu, T, Matsumata, T, Takenaka, K, Sugimachi, K
This report attempts to elucidate the manner in which the surgical margin is linked to a recurrence after curative hepatectomy for hepatocellular carcinoma (HCC) in patients with cirrhosis. Forty...
Novel immunosuppressive effect of FK506 by augmentation of T cell apoptosis
Hashimoto, Y, Matsuoka, N, Kawakami, A, Tsuboi, M, Nakashima, T, Eguchi, K, ...
We have recently reported the accumulation of oligoclonal activated T cells in the spontaneously developed autoimmune pancreatitis in aly/aly mouse. In this study, we examined the effects of FK506 in...
A safe and simple technique for exchanging central venous catheters.
Shimada, M., Matsumata, T., Wakiyama, S., Maeda, T., Kanematsu, T., Sugimachi, K.
A safe and simple technique for exchanging central venous catheters is herein described. Our technique is based on a modification of Seldinger's method, in which a new outer sheath is introduced over...