Direct evaporative cooling of 41K into a Bose-Einstein condensate (2008)
Kishimoto, T., Kobayashi, J., Noda, K., Aikawa, K., Ueda, M., Inouye, S.
We have investigated the collisional properties of 41K atoms at ultracold temperature. To show the possibility to use 41K as a coolant, a Bose-Einstein condensate of 41K atoms in the stretched state...
Neutrino-less Double Beta Decay of 48Ca studied by CaF2(Eu) Scintillators (2008)
Umehara, S., Kishimoto, T., Ogawa, I., Hazama, R., Miyawaki, H., Yoshida, S., ...
We searched for the neutrino-less double beta decay(0nbb) of 48Ca by using CaF2(Eu) scintillators. Analysis of their pulse shapes was effective to reduce backgrounds. No events are observed in the...
Yokota, S, Imagawa, T, Miyamae, T, Kasai, K, Mori, M, Nishimoto, N, ...
No abstract available.
Challenge on Ca-48 enrichment for CANDLES double beta decay experiment (2007)
Hazama, R., Tatewaki, Y., Kishimoto, T., Matsuoka, K., Endo, N., Kume, K., ...
Chemical isotope effects of calcium were studied by liquid-liquid extraction using a crown ether of dicyclohexano-18-crown-6 for the purpose of finding a cost-effective and efficient way of...
Electrodynamic trapping of spinless neutral atoms with an atom chip (2006)
Kishimoto, T., Hachisu, H., Fujiki, J., Nagato, K., Yasuda, M., Katori, H.
Three dimensional electrodynamic trapping of neutral atoms has been demonstrated. By applying time-varying inhomogeneous electric fields with micron-sized electrodes, nearly $10^2$ strontium atoms in...
Doganci, A., Eigenbrod, T., Krug, N., Sanctis, G.T. De, Hausding, M., Erpenbeck, V.J., ...
The cytokine IL-6 acts via a specific receptor complex that consists of the membrane-bound IL-6 receptor (mIL-6R) or the soluble IL-6 receptor (sIL-6R) and glycoprotein 130 (gp130). In this study, we...
Mesonic and nonmesonic weak decay widths of medium-heavy lambda hypernuclei (2004)
Sato, Y., Ajimura, S., Aoki, K., Bhang, H., Hasegawa, T., Hashimoto, O., ...
We have measured the energy spectra of pions and protons emitted in the weak decay of 12_Lambda_C, 28_Lambda_Si, and Lambda_Fe hypernuclei produced via the (pi+, K+) reaction. The decay widths of the...
Saha, P. K., Noumi, H., Abe, D., Ajimura, S., Aoki, K., Bhang, H. C., ...
In order to study the Sigma-nucleus optical potential, we measured inclusive (pi^-,K^+) spectra on medium-to-heavy nuclear targets: CH_2, Si, Ni, In and Bi. The CH_2 target was used to calibrate the...
Pathogenic roles of IL-6 and IL-6 blocking therapy on rheumatoid arthritis (2003)
Yoshizaki, K, Nishimoto, N, Miyasaka, N, Yamamoto, K, Kawai, S, Takeuchi, T, ...
No abstract available.
Choy, E.H.S., Isenberg, D.A., Garrood, T., Farrow, S., Ioannou, Y., Bird, H., ...
Objective: To investigate the safety and efficacy of MRA, a recombinant human anti-interleukin-6 (anti-IL-6) receptor monoclonal antibody of the IgG1 subclass that inhibits the function of IL-6, in...
Scintillation efficiency of nuclear recoils in a CaF-2(Eu) crystal for dark matter search (2001)
Hazama, R., Ajimura, S., Hayakawa, H., Matsuoka, K., Miyawaki, H., Morikubo, K., ...
The scintillation efficiency (quenching factor) of fluorine and calcium nuclei recoiling in a CaF-2(Eu) crystal was measured in an energy region relevant to dark matter searches. The recoiling nuclei...
H. Bhang, H. Park, J. H. Kim, Y. D. Kim, M. Youn, O. Hashimoto, ...
this report, I will concentrate on the weak decay aspects of medium to heavy hypernuclei. The experimental data are from the experiments, KEK-PS E307
Mass Dependence of Lifetimes of (1999)
H. Bhang, H. Park, Y. D. Kim, M. Youn, O. Hashimoto, K. Maeda, ...
Introduction In this workshop we have seen much of concerns and activities on the - and double -hypernucleus. However, so far the only hypernuceus where the realistic spectroscopic and decay studies...
Spin observables in the $pn \to p \Lambda$ reaction (1998)
Nabetani, H., Ogaito, T., Sato, T., Kishimoto, T.
The T matrix of the LambdaN-> NN reaction, which is a strangeness changing weak process, is derived. The explicit formulas of the spin observables are given for s-wave p-Lambda final states which...
Polarization of $^{5}_{\Lambda}He$ produced by the $(\pi^{+}, K^{+})$ reaction (1998)
Ajimura, S, Ishikawa, M, Ikeda, K, Kishimoto, T, Okusu, A, Shinkai, N, ...
CD Antigens 1996: announcement (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, M., Moretta, L., ...
Update of CD antigens, 1996 (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, M., Moretta, L., ...
Update: new CD antigens, 1996 (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, M., Moretta, L., ...
CD antigens 1996: announcement (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, L., Moretta, L., ...
Update: new CD antigens, 1996 (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, L., Moretta, L., ...
Update of CD antigens, 1996 (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, L., Moretta, L., ...
CD Antigens 1996: announcement (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, M., Moretta, L., ...
Update of CD antigens, 1996 (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, M., Moretta, L., ...
Update: new CD antigens, 1996 (1997)
Kishimoto, T., Goyert, S., Kikutani, H., Mason, D., Miyasaka, M., Moretta, L., ...
Self-Consistent Velocity Dependent Effective Interactions (1996)
Kubo, T., Sakamoto, H., Kammuri, T., Kishimoto, T.
The theory of self-consistent effective interactions in nuclei is extended for a system with a velocity dependent mean potential. By means of the field coupling method, we present a general...
Hypernuclear weak decay of $_{\Lambda}^{12}$C and $_{\Lambda}^{11}$B (1995)
Noumi, H, Ajimura, S, Ejiri, H, Higashi, A, Kishimoto, T, Gill, D R, ...
The superconducting kaon spectrometer: SKS (1994)
Fukuda, T, Hasegawa, T, Hashimoto, O, Higashi, A, Homma, S, Kitami, T, ...
The $\Lambda$ hypernuclear spectroscopy with the SKS spectrometer at KEK 12 GeV PS (1994)
Ajimura, S, Aoki, K, Bhang, H C, Gavrilov, Yu K, Hasegawa, T, Hashimoto, O, ...
Hasegawa, T, Hashimoto, O, Homma, S, Miyachi, T, Nagae, T, Sekimoto, M, ...
K$^+$-nucleus quasielastic scattering (1993)
Kormanyos, C. M., Peterson, R. J., Shepard, J. R., Wise, J. E., Bart, S., Chrien, R. E., ...
K$^+$--nucleus quasielastic cross sections measured for a laboratory kaon beam momentum of 705 MeV/$c$ are presented for 3--momentum transfers of 300 and 500 MeV/$c$. The measured differential cross...
EXPERIMENTAL-STUDY OF A CO2-LASER PLASMA BY COHERENT ANTI-STOKES-RAMAN SCATTERING (CARS) (1992)
Kishimoto, T., Wenzel, N., Grossewilde, H., Lupke, G., Marowsky, G.
THERMAL DISEQUILIBRIUM EFFECTS IN A MOLECULAR GLOW-DISCHARGE (1992)
Lupke, G., Marowsky, G., Sieverdes, F., Wenzel, N., Kishimoto, T., Grossewilde, H.
Sasaki, K, Yagi, H, Bronson, R T, Tominaga, K, Matsunashi, T, Deguchi, K, ...
Core binding factor beta (CBF beta) is considered to be a transcriptional coactivator that dimerizes with transcription factors core binding factor alpha 1 (CBFA1), -2, and -3, and enhances DNA...
Minami, M, Inoue, M, Wei, S, Takeda, K, Matsumoto, M, Kishimoto, T, ...
Myeloid leukemia M1 cells can be induced for growth arrest and terminal differentiation into macrophages in response to interleukin 6 (IL-6) or leukemia inhibitory factor (LIF). Recently, a large...
Yoshida, K, Taga, T, Saito, M, Suematsu, S, Kumanogoh, A, Tanaka, T, ...
gp130 is a ubiquitously expressed signal-transducing receptor component shared by interleukin 6, interleukin 11, leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and...
Hirota, H, Yoshida, K, Kishimoto, T, Taga, T
To investigate the physiological roles of gp130 in detail and to determine the pathological consequence of abnormal activation of gp130, transgenic mice having continuously activated gp130 were...
Sui, X, Tsuji, K, Tanaka, R, Tajima, S, Muraoka, K, Ebihara, Y, ...
gp130, a signal-transducing receptor component of interleukin 6 (IL-6), associates with an IL-6 and IL-6 receptor (IL-6) complex and transduces signals. To examine the role of gp130 signaling in the...
A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle.
Kishimoto, T, Pearse, R V, Lin, C R, Rosenfeld, M G
Corticotropin-releasing factor (CRF) mediates many critical aspects of the physiological response to stress. These effects are elicited by binding to specific high-affinity receptors, which are...
Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.
Narazaki, M, Witthuhn, B A, Yoshida, K, Silvennoinen, O, Yasukawa, K, Ihle, J N, ...
The interleukin 6 receptor-associated signal transducer, gp130, is shared by receptor complexes for leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and interleukin 11. We show...
Molecular cloning and structure of a pre-B-cell growth-stimulating factor.
Nagasawa, T, Kikutani, H, Kishimoto, T
Generation and proliferation of early B-cell progenitors have been known to require stromal cell-derived molecules. A stromal cell line, PA6, was found to produce a soluble mediator, which was...
Nakajima, T, Kinoshita, S, Sasagawa, T, Sasaki, K, Naruto, M, Kishimoto, T, ...
NF-IL6, a member of the basic leucine zipper (bZIP) family transcription factors, is involved in expression of inducible genes involved in immune and inflammatory responses. We observed that...
Matsusaka, T, Fujikawa, K, Nishio, Y, Mukaida, N, Matsushima, K, Kishimoto, T, ...
Single binding sites for transcription factors NF-IL6 and NF-kappa B are present in the promoter of the interleukin (IL) 6 gene. Previous studies of internally deleted promoter mutants demonstrated...
Suematsu, S, Matsusaka, T, Matsuda, T, Ohno, S, Miyazaki, J, Yamamura, K, ...
The mechanisms through which pristane or mineral oil can induce plasmacytomas in BALB/c or NZB mice are not fully understood, but involvement of interleukin 6 (IL-6), a growth factor for...
Kinoshita, S, Akira, S, Kishimoto, T
Using a DNA probe from the DNA-binding portion of the NF-IL6 gene and an antibody against the DNA-binding domain of NF-IL6, we isolated a gene homologous to NF-IL6 in the DNA-binding and leucine...
Yokota, A, Yukawa, K, Yamamoto, A, Sugiyama, K, Suemura, M, Tashiro, Y, ...
We have previously identified two species of the low-affinity human Fc receptor for IgE, Fc epsilon RIIa and Fc epsilon RIIb, which differ only in a short stretch of amino acids at the N-terminal...
Taga, T, Narazaki, M, Yasukawa, K, Saito, T, Miki, D, Hamaguchi, M, ...
Functional pleiotropy and redundancy are characteristic features of cytokines. To understand the signaling mechanisms of such cytokines, we have proposed a two-chain interleukin (IL) 6 receptor...
Murakami, M, Narazaki, M, Hibi, M, Yawata, H, Yasukawa, K, Hamaguchi, M, ...
Interleukin 6 (IL-6) signal is transduced through gp130 that associates with a complex of IL-6 and IL-6 receptor. Truncations or amino acid substitutions offe introduced in the cytoplasmic region of...
AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6.
Miles, S A, Rezai, A R, Salazar-González, J F, Vander Meyden, M, Stevens, R H, Logan, D M, ...
Cell lines derived from Kaposi sarcoma lesions of patients with AIDS (AIDS-KS cells) produce several cytokines, including an endothelial cell growth factor, interleukin 1 beta, and basic fibroblast...
In vitro and in vivo activities of AM-1155, a new fluoroquinolone, against Chlamydia spp.
Miyashita, N, Niki, Y, Kishimoto, T, Nakajima, M, Matsushima, T
The in vitro and in vivo activities of AM-1155, a new quinolone, against Chlamydia spp. were investigated. The MIC of AM-1155 for 10 standard strains of different Chlamydia spp. and 25 wild-type...
Murakami-Mori, K, Taga, T, Kishimoto, T, Nakamura, S
Oncostatin M (OM), which shares functional similarity and structural homology to leukemia inhibitory factor (LIF) and interleukin-6 (IL-6), functions as a potent growth factor for AIDS-associated...
Mima, T, Saeki, Y, Ohshima, S, Nishimoto, N, Matsushita, M, Shimizu, M, ...
To investigate the pathogenicity of T cells infiltrating in the rheumatoid joints, mononuclear cells (MNC), predominantly T cells, isolated from either synovial fluid or synovial tissues of the...
In vitro and in vivo antichlamydial activities of newly developed quinolone antimicrobial agents.
Kimura, M, Kishimoto, T, Niki, Y, Soejima, R
The in vitro and in vivo activities of three newly developed quinolone antimicrobial agents (sparfloxacin, tosufloxacin, and OPC-17116) were investigated. All three agents showed potent in vitro...
Degradation of c-Fos by the 26S proteasome is accelerated by c-Jun and multiple protein kinases.
Tsurumi, C, Ishida, N, Tamura, T, Kakizuka, A, Nishida, E, Okumura, E, ...
c-Fos is associated with c-Jun to increase the transcription of a number of target genes and is a nuclear proto-oncoprotein with a very short half-life. This instability of c-Fos may be important in...
NF-IL6, a member of the C/EBP family, regulates E1A-responsive promoters in the absence of E1A.
Spergel, J M, Hsu, W, Akira, S, Thimmappaya, B, Kishimoto, T, Chen-Kiang, S
A cDNA encoding NF-IL6, an interleukin-6 (IL-6)-regulated human nuclear factor of the C/EBP family, is demonstrated to complement the transactivation function of E1A. The endogenous NF-IL6 level...
Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA element.
Wang, F, Kikutani, H, Tsang, S F, Kishimoto, T, Kieff, E
Epstein-Barr virus (EBV) nuclear protein 2 (EBNA-2) is essential for B-lymphocyte growth transformation. EBNA-2 upregulates mRNAs encoding CD23, a B-lymphocyte surface protein closely associated with...