T. Koike

Publication List Details

Period

1995 - 2009

Number

162

Co-Authors

Step-up therapy with biphasic insulin aspart-70/30 : Sapporo 1-2-3 study (2009)

Yoshioka, N., Kurihara, Y., Manda, N., Komori, K., Kato, M., Kijima, H., ...

The effectiveness of BIAsp 30 step-up therapy in achieving glycemic control in Japanese patients with type 2 diabetes mellitus was investigated. Study subjects were 99 patients with type 2 diabetes...

Deeply-bound $K^- pp$ state in the $^3$He(in-flight $K^-$, $n$) spectrum and its moving pole near the $\pi \Sigma N$ threshold (2009)

Koike, T., Harada, T.

The formation of a deeply-bound $K^- pp$ state with $I=1/2$, $J^\pi=0^-$ by the $^3$He(in-flight $K^-$, $n$) reaction is theoretically investigated in a distorted-wave impulse approximation using the...

The HypHI project: Hypernuclear spectroscopy with stable heavy ion beams and rare isotope beams at GSI and FAIR (2008)

Bianchin, S., Achenbach, P., Ajimura, S., Borodina, O., Fukuda, T., Hoffmann, J., ...

The HypHI collaboration aims to perform a precise hypernuclear spectroscopy with stable heavy ion beams and rare isotope beams at GSI and fAIR in order to study hypernuclei at extreme isospin,...

Solar neutrino measurements in Super-Kamiokande-II (2008)

Cravens, J. P., Abe, K., Iida, T., Ishihara, K., Kameda, J., Koshio, Y., ...

The results of the second phase of the Super-Kamiokande solar neutrino measurement are presented and compared to the first phase. The solar neutrino flux spectrum and time variation as well as...

Les interfaces pour l'intégration de la logistique dans les projets de conception. une contribution basée sur le cas du projet d'un tracteur à chenille (2008)

Koike, T.

Cette thèse présente nos travaux de recherche concernant la problématique de l'intégration de la logistique dans les projets de conception de produits manufacturés. Ces travaux ont été...

Search for matter-dependent atmospheric neutrino oscillations in Super-Kamiokande (2008)

Abe, K., Hayato, Y., Iida, T., Ikeda, M., Kameda, J., Koshio, Y., ...

We consider ν_μ→ν_τ oscillations in the context of the mass varying neutrino (MaVaN) model, where the neutrino mass can vary depending on the electron density along the flight path of the...

Isospin Properties of ($K^-$, $N$) Reactions for the Formation of Deeply-bound Antikaonic Nuclei (2008)

Koike, T., Harada, T.

The formation of deeply-bound antikaonic $K^-/\bar{K}^0$ nuclear states by nuclear ($K^-$, $N$) reactions is investigated theoretically within a distorted-wave impulse approximation (DWIA),...

Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases (2008)

Fukaya, S., Yasuda, S., Hashimoto, T., Oku, K., Kataoka, H., Horita, T., ...

Objectives. Haemophagocytic syndrome (HPS) is known as a relatively rare complication in autoimmune diseases. Here we analysed the clinical features of HPS in patients with systemic autoimmune...

Calculation of the $^3$He(in-flight $K^-$,$n$) reaction for searching the deeply-bound $K^-pp$ state (2007)

Koike, T., Harada, T.

The formation of a deeply-bound $K^-pp$ state by the $^3$He(in-flight $K^-$,$n$) reaction is investigated theoretically in the distorted-wave impulse approximation using the Green's function method....

Effect of ? Softness on the Stability of Chiral Geometry: Spectroscopy of 106Ag (2007)

Joshi, P., Carpenter, M. P., Fossan, D. B., Koike, T., Paul, E. S., Rainovski, G., ...

A study of the nucleus 106Ag has revealed the presence of two strongly coupled negative-parity rotational bands up to the 19- and 20- states, respectively, which cross each other at spin I~14. The...

Quantum Brachistochrone for Mixed States (2007)

Carlini, A., Hosoya, A., Koike, T., Okudaira, Y.

We present a general formalism based on the variational principle for finding the time-optimal quantum evolution of mixed states governed by a master equation, when the Hamiltonian and the Lindblad...

Characteristics of particle size distributions in the tropical tropopause based on optical particle counter and lidar measurements (2007)

Iwasaki, S., Maruyama, K., Hayashi, M., Ogino, S. Y., Ishimoto, H., Tachibana, Y., ...

An optical particle counter (OPC) is used in conjunction with lidar measurements to examine the characteristics of the particle size distribution in cirrus cloud at the tropical tropopause (TT) over...

Characteristics of aerosol and cloud particle size distributions in the tropical tropopause layer measured with optical particle counter and lidar (2007)

Iwasaki, S., Maruyama, K., Hayashi, M., Ishimoto, H., Tachibana, Y., ...

An optical particle counter (OPC) is used in conjunction with lidar measurements to examine the characteristics of the particle size distribution in cirrus cloud in the tropical tropopause layer...

Characteristics of particle size distributions in the tropical tropopause based on optical particle counter and lidar measurements (2007)

Iwasaki, S., Maruyama, K., Hayashi, M., Ogino, S. Y., Ishimoto, H., Tachibana, Y., ...

An optical particle counter (OPC) is used in conjunction with lidar measurements to examine the characteristics of the particle size distribution in cirrus cloud at the tropical tropopause (TT) over...

Characteristics of aerosol and cloud particle size distributions in the tropical tropopause layer measured with optical particle counter and lidar (2007)

Iwasaki, S., Maruyama, K., Hayashi, M., Ishimoto, H., Tachibana, Y., ...

An optical particle counter (OPC) is used in conjunction with lidar measurements to examine the characteristics of the particle size distribution in cirrus cloud in the tropical tropopause layer...

Characteristics of aerosol and cloud particle size distributions in the tropical tropopause layer measured with optical particle counter and lidar (2007)

S. Iwasaki, K. Maruyama, M. Hayashi, H. Ishimoto, Y. Tachibana, ...

An optical particle counter (OPC) is used in conjunction with lidar measurements to examine the characteristics of the particle size distribution in cirrus cloud in the tropical tropopause layer...

Characteristics of particle size distributions in the tropical tropopause based on optical particle counter and lidar measurements (2007)

S. Iwasaki, K. Maruyama, M. Hayashi, S. Y. Ogino, H. Ishimoto, Y. Tachibana, ...

An optical particle counter (OPC) is used in conjunction with lidar measurements to examine the characteristics of the particle size distribution in cirrus cloud at the tropical tropopause (TT) over...

Seasonal changes in the photosynthetic capacity of cones on a larch (Larix kaempferi) canopy (2006)

Watanabe, Y., Endo, I., Kitaoka, S., Koike, T.

The seasonal changes of photosynthesis of cones of Japanese larch (Larix kaempferi Carr.) trees showed that gross photosynthetic rate of young cones (P G) was 2–3 µmol m−2 s−1 at surface area...

Seasonal changes in the photosynthetic capacity of cones on a larch (Larix kaempferi) canopy (2006)

Watanabe, Y., Endo, I., Kitaoka, S., Koike, T.

The seasonal changes of photosynthesis of cones of Japanese larch (Larix kaempferi Carr.) trees showed that gross photosynthetic rate of young cones (P G) was 2–3 µmol m-2 s-1 at surface area unit...

Seasonal changes in the photosynthetic capacity of cones on a larch (Larix kaempferi) canopy (2006)

Watanabe, Y., Endo, I., Kitaoka, S., Koike, T.

The seasonal changes of photosynthesis of cones of Japanese larch (Larix kaempferi Carr.) trees showed that gross photosynthetic rate of young cones (P G) was 2–3 µmol m-2 s-1 at surface area unit...

Effect of the shape anisotropy on the magnetic configuration of (Ga,Mn)As and its evolution with temperature (2006)

Hamaya, K., Taniyama, T., Koike, T., Yamazaki, Y.

We study the effect of the shape anisotropy on the magnetic domain configurations of a ferromagnetic semiconductor (Ga,Mn)As/GaAs(001) epitaxial wire as a function of temperature. Using...

Growth and photosynthetic responses of two pine species (Pinus koraiensis and P. rigida) in a polluted industrial region in Korea (2006)

Choi, D. S., Kayama, M., Jin, H. O., Lee, C. H., Izuta, T., Koike, T., ...

We investigated the effects of pollutants on two pine species (Pinus koraiensis and P. rigida) in an industrial region in Korea, using a physiological approach. The concentrations of fluorine (F) and...

Growth and photosynthetic responses of two pine species (Pinus koraiensis and P. rigida) in a polluted industrial region in Korea (2006)

Choi, D. S., Kayama, M., Jin, H. O., Lee, C. H., Izuta, T., Koike, T.

We investigated the effects of pollutants on two pine species (Pinus koraiensis and P. rigida) in an industrial region in Korea, using a physiological approach. The concentrations of fluorine (F) and...

Growth and photosynthetic responses of two pine species (Pinus koraiensis and P. rigida) in a polluted industrial region in Korea (2006)

Choi, D. S., Kayama, M., Jin, H. O., Lee, C. H., Izuta, T., Koike, T.

We investigated the effects of pollutants on two pine species (Pinus koraiensis and P. rigida) in an industrial region in Korea, using a physiological approach. The concentrations of fluorine (F) and...

Measurement of the kaonic Hydrogen X-ray spectrum (2005)

Beer, G., Bragadireanu, A. M., Cargnelli, M., Curceanu-Petrascu, C., Fuhrmann, H., ...

The DEAR (DAΦNE exotic atom research) experiment measured the energy of x rays emitted in the transitions to the ground state of kaonic hydrogen. The measured values for the shift ε and the width...

Measurement of the kaonic Hydrogen X-ray spectrum (2005)

Beer, G., Bragadireanu, A. M., Cargnelli, M., Curceanu-Petrascu, C., Fuhrmann, H., ...

The DEAR (DAΦNE exotic atom research) experiment measured the energy of x rays emitted in the transitions to the ground state of kaonic hydrogen. The measured values for the shift ε and the width...

Dynamic relaxation of magnetic clusters in a ferromagnetic (Ga,Mn)As epilayer (2005)

Hamaya, K., Koike, T., Taniyama, T., Fujii, T., Kitamoto, Y., Yamazaki, Y.

A new scenario of the mechanism of intriguing ferromagnetic properties in Mn-doped magnetic semiconductor (Ga,Mn)As is examined in detail. We find that magnetic features seen in zero-field cooled and...

Triaxiality, chirality and gamma-softness (2005)

Starosta, K., Caprio, M. A., Koike, T., Kruecken, R., Vaman, C.

Current work explores the impact of gamma-softness on partner bands built on the h11/2h11/2 proton-particle-neutron-hole configurations in triaxial odd-odd nuclei. The results of calculations...

Kaonic nitrogen X-ray transition yields in a gaseous target (2005)

Ishiwatari, T., Beer, G., Bragadireanu, A. M., Cargnelli, M., Curceanu-Petrascu, C., ...

The first measurement of the yields of three kaonic nitrogen X-ray transitions, using the DEAR (DAΦNE Exotic Atom Research) setup at the DAΦNE collider of Frascati, is reported. The yields are...

Kaonic nitrogen X-ray transition yields in a gaseous target (2005)

Ishiwatari, T., Beer, G., Bragadireanu, A. M., Cargnelli, M., Curceanu-Petrascu, C., ...

The first measurement of the yields of three kaonic nitrogen X-ray transitions, using the DEAR (DAΦNE Exotic Atom Research) setup at the DAΦNE collider of Frascati, is reported. The yields are...

High-spin structure of $^{102}$Ru (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus 102Ru have been studied through the 96Zr(13C,alpha3n) reaction using the EUROBALL IV gamma-ray spectrometer accompanied by the DIAMANT array for the detection of...

Composite chiral bands in the A $\sim$ 105 mass region (2005)

Timar, J., Vaman, C., Starosta, K., Joshi, P., Dimitrov, V.I., Fossan, D.B., ...

Composite chiral bands, corresponding to the $\pi g_{9/2}\nu (h_{11/2})^2$ quasiparticle configuration, were observed in $^{103}Rh and $^{105}$Rh. The behaviour of these bands were compared with that...

High-spin structure of $^{102}Ru$ (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus $^{102}Ru$ have been investigated via the $^{96}Zr(^{13}C,\alpha3n)$ reaction at beam energies of 51 and 58 MeV, using the EUROBALL IV gamma-ray spectrometer and the...

High-spin structure of $^{102}$Ru (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus 102Ru have been studied through the 96Zr(13C,alpha3n) reaction using the EUROBALL IV gamma-ray spectrometer accompanied by the DIAMANT array for the detection of...

Composite chiral bands in the A $\sim$ 105 mass region (2005)

Timar, J., Vaman, C., Starosta, K., Joshi, P., Dimitrov, V.I., Fossan, D.B., ...

Composite chiral bands, corresponding to the $\pi g_{9/2}\nu (h_{11/2})^2$ quasiparticle configuration, were observed in $^{103}Rh and $^{105}$Rh. The behaviour of these bands were compared with that...

High-spin structure of $^{102}Ru$ (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus $^{102}Ru$ have been investigated via the $^{96}Zr(^{13}C,\alpha3n)$ reaction at beam energies of 51 and 58 MeV, using the EUROBALL IV gamma-ray spectrometer and the...

Composite chiral bands in the A $\sim$ 105 mass region (2005)

Timar, J., Vaman, C., Starosta, K., Joshi, P., Dimitrov, V.I., Fossan, D.B., ...

Composite chiral bands, corresponding to the $\pi g_{9/2}\nu (h_{11/2})^2$ quasiparticle configuration, were observed in $^{103}Rh and $^{105}$Rh. The behaviour of these bands were compared with that...

High-spin structure of $^{102}Ru$ (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus $^{102}Ru$ have been investigated via the $^{96}Zr(^{13}C,\alpha3n)$ reaction at beam energies of 51 and 58 MeV, using the EUROBALL IV gamma-ray spectrometer and the...

High-spin structure of $^{102}$Ru (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus 102Ru have been studied through the 96Zr(13C,alpha3n) reaction using the EUROBALL IV gamma-ray spectrometer accompanied by the DIAMANT array for the detection of...

High-spin structure of $^{102}$Ru (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus 102Ru have been studied through the 96Zr(13C,alpha3n) reaction using the EUROBALL IV gamma-ray spectrometer accompanied by the DIAMANT array for the detection of...

Composite chiral bands in the A $\sim$ 105 mass region (2005)

Timar, J., Vaman, C., Starosta, K., Joshi, P., Dimitrov, V.I., Fossan, D.B., ...

Composite chiral bands, corresponding to the $\pi g_{9/2}\nu (h_{11/2})^2$ quasiparticle configuration, were observed in $^{103}Rh and $^{105}$Rh. The behaviour of these bands were compared with that...

High-spin structure of $^{102}Ru$ (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus $^{102}Ru$ have been investigated via the $^{96}Zr(^{13}C,\alpha3n)$ reaction at beam energies of 51 and 58 MeV, using the EUROBALL IV gamma-ray spectrometer and the...

Les interfaces pour l'intégration de la logistique dans les projets de conception. une contribution basée sur le cas du projet d'un tracteur à chenille (2005)

Koike, T.

Cette thèse présente nos travaux de recherche concernant la problématique de l'intégration de la logistique dans les projets de conception de produits manufacturés. Ces travaux ont été...

Les interfaces pour l'intégration de la logistique dans les projets de conception. une contribution basée sur le cas du projet d'un tracteur à chenille (2005)

Koike, T.

Cette thèse présente nos travaux de recherche concernant la problématique de l'intégration de la logistique dans les projets de conception de produits manufacturés. Ces travaux ont été...

Les interfaces pour l'intégration de la logistique dans les projets de conception. une contribution basée sur le cas du projet d'un tracteur à chenille (2005)

Koike, T.

Cette thèse présente nos travaux de recherche concernant la problématique de l'intégration de la logistique dans les projets de conception de produits manufacturés. Ces travaux ont été...

High-spin structure of $^{102}Ru$ (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus $^{102}Ru$ have been investigated via the $^{96}Zr(^{13}C,\alpha3n)$ reaction at beam energies of 51 and 58 MeV, using the EUROBALL IV gamma-ray spectrometer and the...

High-spin structure of $^{102}$Ru (2005)

Sohler, D., Timar, J., Rainovski, G., Joshi, P., Starosta, K., Fossan, D.B., ...

High-spin states in the nucleus 102Ru have been studied through the 96Zr(13C,alpha3n) reaction using the EUROBALL IV gamma-ray spectrometer accompanied by the DIAMANT array for the detection of...

Composite chiral bands in the A $\sim$ 105 mass region (2005)

Timar, J., Vaman, C., Starosta, K., Joshi, P., Dimitrov, V.I., Fossan, D.B., ...

Composite chiral bands, corresponding to the $\pi g_{9/2}\nu (h_{11/2})^2$ quasiparticle configuration, were observed in $^{103}Rh and $^{105}$Rh. The behaviour of these bands were compared with that...

Diurnal and inter-monthly variation of land surface heat fluxes over the central Tibetan Plateau area (2005)

Ma, Y.M., Fan, S., Ishikawa, H., Tsukamoto, O., Yao, T., Koike, T., ...

The energy and water cycle over the Tibetan Plateau play an important role in the Asian monsoon system, which in turn is a major component of both the energy and water cycles of the global climate...

Retrieval of Soil Moisture from AMSR Data (2004)

Njoku, E., Koike, T., Jackson, T., Paloscia, S.

In this paper we discuss the potential and problems of soil moisture sensing using AMSR data that will become available in late 2000 or early 2001.

The cold land processes experiment (CLPX) local scale observatin site (LSOS) (2004)

McDonald, K. C., Hardy, J. P., Cline, D., Elder, K., Davis, R., Pomeroy, J., ...

The Local Scale Observation Site (LSOS) is the smallest study site of the Cold LandProcesses Experiment (CLPX) and is located within the Fraser Meso-cell Study Area (MSA), near the Fraser...

Stability of chiral geometry in the odd-odd Rh isotopes: spectroscopy of 106Rh (2004)

Joshi, P., Jenkins, D.G., Raddon, P.M., Simons, A.J., Wadsworth, R., Wilkinson, A.R., ...

The nucleus 106Rh was populated using the reaction 96Zr(13C, p2n) at a beam energy of 51 MeV. γ-ray transitions were identified using the EUROBALL-IV γ-ray spectrometer and the DIAMANT charged...

Experimental evidence for chirality in the odd-A $^{105}$Rh (2004)

Timar, J., Joshi, P., Starosta, K., Dimitrov, V.I., Fossan, DS.B., Molnar, J., ...

High-spin states in 105Rh were populated by the 96Zr(13C, p3n) reaction at beam energies of 51 and 58 MeV, and studied using the EUROBALL IV γ-ray spectrometer and the DIAMANT charged particle...

Experimental evidence for chirality in the odd-A $^{105}$Rh (2004)

Timar, J., Joshi, P., Starosta, K., Dimitrov, V.I., Fossan, DS.B., Molnar, J., ...

High-spin states in 105Rh were populated by the 96Zr(13C, p3n) reaction at beam energies of 51 and 58 MeV, and studied using the EUROBALL IV γ-ray spectrometer and the DIAMANT charged particle...

A Composite Chiral Pair of Rotational Bands in the odd-A Nucleus 135Nd (2003)

Zhu, S., Garg, U., Nayak, B. K., Ghugre, S. S., Pattabiraman, N. S., Fossan, D. B., ...

High-spin states in 135Nd were populated with the 110Pd(30Si,5n)135Nd reaction at a 30Si bombarding energy of 133 MeV. Two Delta(I)=1 bands with close excitation energies and the same parity were...

On measuring and remote sensing surface energy partitioning over the Tibetan Plateau (2003)

Ma, Y., Su, Z., Koike, T., Yao, T., Ishikawa, H., Ueno, K., ...

The energy and water cycle over the Tibetan Plateau play an important role in the Asian monsoon system, which in turn is a major component of both the energy and water cycles of the global climate...

On measuring and remote sensing surface energy partitioning over the Tibetan Plateau (2003)

Ma, Y., Su, Z., Koike, T., Yao, T., Ishikawa, H., Ueno, K., ...

The energy and water cycle over the Tibetan Plateau play an important role in the Asian monsoon system, which in turn is a major component of both the energy and water cycles of the global climate...

Cerebral imaging by magnetic resonance imaging and single photon emission computed tomography in systemic lupus erythematosus with central nervous system involvement (2003)

Oku, K., Atsumi, T., Furukawa, S., Horita, T., Sakai, Y., Jodo, S., ...

Objective. To assess the significance of magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) abnormalities in patients with systemic lupus erythematosus (SLE)....

Cerebral imaging by magnetic resonance imaging and single photon emission computed tomography in systemic lupus erythematosus with central nervous system involvement (2003)

Oku, K., Atsumi, T., Furukawa, S., Horita, T., Sakai, Y., Jodo, S., ...

Objective. To assess the significance of magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) abnormalities in patients with systemic lupus...

Cerebral imaging by magnetic resonance imaging and single photon emission computed tomography in systemic lupus erythematosus with central nervous system involvement (2003)

Oku, K., Atsumi, T., Furukawa, S., Horita, T., Sakai, Y., Jodo, S., ...

Objective. To assess the significance of magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) abnormalities in patients with systemic lupus erythematosus (SLE)....

Determination of regional net radiation and soil heat flux over a heterogeneous landscape of the Tibetan Plateau (2002)

Ma, Y., Su, Z., Li, Z., Koike, T., Menenti, M.

This paper explores the potential for documenting regional fields of surface energy fluxes over the Tibetan plateau using published algorithms and previously calibrated empirical formulae with data...

Correlation between {beta}2-glycoprotein I valine/leucine247 polymorphism and anti-{beta}2-glycoprotein I antibodies in patients with primary antiphospholipid syndrome (1999)

Atsumi, T., Tsutsumi, A., Amengual, O., Khamashta, M. A., Hughes, G. R. V., Miyoshi, Y., ...

Objectives. β2-Glycoprotein I (β2GPI) exon 7 polymorphism leads to a valine–leucine amino acid exchange at position 247 in domain 5 of β2GPI, between the phospholipid binding site and the...

SPECIFICITY OF ELISA FOR ANTIBODY TO {beta}2-GLYCOPROTEIN I IN PATIENTS WITH ANTIPHOSPHOLIPID SYNDROME (1996)

AMENGUAL, O., ATSUMI, T., KHAMASHTA, M. A., KOIKE, T., HUGHES, G. R. V.

The clinical significance of anti-β2 glycoprotein I (β2-GPI) antibodies was evaluated in patients with antiphospholipid syndrome (APS), primary and secondary to systemic lupus erythematosus (SLE)....

Evidence that nerve growth factor dependence of sympathetic neurons for survival in vitro may be determined by levels of cytoplasmic free Ca2+.

Koike, T, Tanaka, S

Developing sympathetic neurons established in the presence of nerve growth factor (NGF) die in vitro after acute withdrawal of NGF. This in vitro model mimics the physiological situation in which...

Role of 1,25-dihydroxycholecalciferol in growth-plate cartilage: inhibition of terminal differentiation of chondrocytes in vitro and in vivo.

Kato, Y, Shimazu, A, Iwamoto, M, Nakashima, K, Koike, T, Suzuki, F, ...

The effects of vitamin D metabolites on alkaline phosphatase [ALPase; orthophosphoric-monoester phosphohydrolase (alkaline optimum), EC 3.1.3.1] activity, a marker of terminal differentiation, in...

Predominant expansion of V gamma 9/V delta 2 T cells in a tularemia patient.

Sumida, T, Maeda, T, Takahashi, H, Yoshida, S, Yonaha, F, Sakamoto, A, ...

We describe a 58-year-old man with tularemia and expanding gamma delta T cells in his peripheral blood lymphocytes (PBL) (32.7% of total PBL). In the present work, we analyzed the T-cell receptor V...

Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: regulation by transforming growth factor beta and serum factors.

Kato, Y, Iwamoto, M, Koike, T, Suzuki, F, Takano, Y

Rabbit chondrocyte cultures on plastic dishes are capable of depositing a cartilaginous matrix, although the matrix does not calcify unless high levels of phosphate are added to the medium. In the...

Effects of interleukin-1 on syntheses of alkaline phosphatase, type X collagen, and 1,25-dihydroxyvitamin D3 receptor, and matrix calcification in rabbit chondrocyte cultures.

Kato, Y, Nakashima, K, Iwamoto, M, Murakami, H, Hiranuma, H, Koike, T, ...

The effect of IL-1 on expression of the mineralization-related phenotype by chondrocytes was examined. In cultures of rabbit growth plate chondrocytes, IL-1 beta at 0.1 ng/ml caused 95% decreases in...

Potent mitogenic effects of parathyroid hormone (PTH) on embryonic chick and rabbit chondrocytes. Differential effects of age on growth, proteoglycan, and cyclic AMP responses of chondrocytes to PTH.

Koike, T, Iwamoto, M, Shimazu, A, Nakashima, K, Suzuki, F, Kato, Y

The effect of PTH on chondrocyte proliferation as a function of cartilage age was examined. PTH[1-34] induced a 12- to 15-fold increase in the efficiency of colony formation in soft agar by...

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.

Koike, T, Martin, D P, Johnson, E M

Sympathetic neurons depend on nerve growth factor (NGF) for their survival both in vivo and in vitro; these cells die upon acute deprivation of NGF. We studied the effects of agents that cause...

T cell receptor repertoire of infiltrating T cells in lips of Sjögren's syndrome patients.

Sumida, T, Yonaha, F, Maeda, T, Tanabe, E, Koike, T, Tomioka, H, ...

Infiltrating T cells around salivary glands in the lips of Sjögren's syndrome (SjS) patients are crucial in the pathogenesis of this disease. To analyze the nature of infiltrating T cells, their T...

Anti-beta2-glycoprotein I (beta2GPI) monoclonal antibodies with lupus anticoagulant-like activity enhance the beta2GPI binding to phospholipids.

Takeya, H, Mori, T, Gabazza, E C, Kuroda, K, Deguchi, H, Matsuura, E, ...

beta2-Glycoprotein I (beta2GPI), a plasma glycoprotein with phospholipid-binding property, is known to be the actual target antigen for autoimmune type anticardiolipin antibodies (aCLs). Certain...

Evidence that nerve growth factor dependence of sympathetic neurons for survival in vitro may be determined by levels of cytoplasmic free Ca2+.

Koike, T, Tanaka, S

Developing sympathetic neurons established in the presence of nerve growth factor (NGF) die in vitro after acute withdrawal of NGF. This in vitro model mimics the physiological situation in which...

Role of 1,25-dihydroxycholecalciferol in growth-plate cartilage: inhibition of terminal differentiation of chondrocytes in vitro and in vivo.

Kato, Y, Shimazu, A, Iwamoto, M, Nakashima, K, Koike, T, Suzuki, F, ...

The effects of vitamin D metabolites on alkaline phosphatase [ALPase; orthophosphoric-monoester phosphohydrolase (alkaline optimum), EC 3.1.3.1] activity, a marker of terminal differentiation, in...

Predominant expansion of V gamma 9/V delta 2 T cells in a tularemia patient.

Sumida, T, Maeda, T, Takahashi, H, Yoshida, S, Yonaha, F, Sakamoto, A, ...

We describe a 58-year-old man with tularemia and expanding gamma delta T cells in his peripheral blood lymphocytes (PBL) (32.7% of total PBL). In the present work, we analyzed the T-cell receptor V...

Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: regulation by transforming growth factor beta and serum factors.

Kato, Y, Iwamoto, M, Koike, T, Suzuki, F, Takano, Y

Rabbit chondrocyte cultures on plastic dishes are capable of depositing a cartilaginous matrix, although the matrix does not calcify unless high levels of phosphate are added to the medium. In the...

Effects of interleukin-1 on syntheses of alkaline phosphatase, type X collagen, and 1,25-dihydroxyvitamin D3 receptor, and matrix calcification in rabbit chondrocyte cultures.

Kato, Y, Nakashima, K, Iwamoto, M, Murakami, H, Hiranuma, H, Koike, T, ...

The effect of IL-1 on expression of the mineralization-related phenotype by chondrocytes was examined. In cultures of rabbit growth plate chondrocytes, IL-1 beta at 0.1 ng/ml caused 95% decreases in...

Potent mitogenic effects of parathyroid hormone (PTH) on embryonic chick and rabbit chondrocytes. Differential effects of age on growth, proteoglycan, and cyclic AMP responses of chondrocytes to PTH.

Koike, T, Iwamoto, M, Shimazu, A, Nakashima, K, Suzuki, F, Kato, Y

The effect of PTH on chondrocyte proliferation as a function of cartilage age was examined. PTH[1-34] induced a 12- to 15-fold increase in the efficiency of colony formation in soft agar by...

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.

Koike, T, Martin, D P, Johnson, E M

Sympathetic neurons depend on nerve growth factor (NGF) for their survival both in vivo and in vitro; these cells die upon acute deprivation of NGF. We studied the effects of agents that cause...

T cell receptor repertoire of infiltrating T cells in lips of Sjögren's syndrome patients.

Sumida, T, Yonaha, F, Maeda, T, Tanabe, E, Koike, T, Tomioka, H, ...

Infiltrating T cells around salivary glands in the lips of Sjögren's syndrome (SjS) patients are crucial in the pathogenesis of this disease. To analyze the nature of infiltrating T cells, their T...

Anti-beta2-glycoprotein I (beta2GPI) monoclonal antibodies with lupus anticoagulant-like activity enhance the beta2GPI binding to phospholipids.

Takeya, H, Mori, T, Gabazza, E C, Kuroda, K, Deguchi, H, Matsuura, E, ...

beta2-Glycoprotein I (beta2GPI), a plasma glycoprotein with phospholipid-binding property, is known to be the actual target antigen for autoimmune type anticardiolipin antibodies (aCLs). Certain...

Somatostatin receptors on human lymphocytes and leukaemia cells.

Hiruma, K, Koike, T, Nakamura, H, Sumida, T, Maeda, T, Tomioka, H, ...

Receptors for somatostatin were identified on mitogen-activated human peripheral blood lymphocytes (PBL) and human leukaemic cells in 87.5% of lymphoblastic leukaemia and in 12.5% of non-lymphocytic...

V gene analysis of anti-cardiolipin antibodies from (NZW x BXSB) F1 mice.

Kita, Y, Sumida, T, Iwamoto, I, Yoshida, S, Koike, T

In (NZW x BXSB) F1 (W/B F1) male mice, systemic lupus-like disease, thrombocytopenia and coronary vascular disease with myocardial infarction occur, due to the presence of platelet-associated...

T-cell receptor V beta repertoire of L3T4+ regulatory T cells in anti-L3T4 antibody-induced tolerant NOD mice.

Sakamoto, A, Furukawa, M, Iwamoto, I, Koike, T, Tomioka, H, Sumida, T

In ongoing studies, we have found that short-term administration of anti-L3T4 monoclonal antibodies (mAb) prevents the development of overt diabetes in non-obese diabetic (NOD) mice. In the present...

Identification of lymphoid cell lines bearing receptors for somatostatin.

Nakamura, H, Koike, T, Hiruma, K, Sato, T, Tomioka, H, Yoshida, S

The MT-2, derived from an adult T-cell leukaemia (ATL) cell, the Molt-4F, a human T-cell line, and the Isk, an EB virus-transformed B-cell line, were found to have high-affinity receptors for...

Protein losing enteropathy associated with collagen diseases.

Tsutsumi, A, Sugiyama, T, Matsumura, R, Sueishi, M, Takabayashi, K, Koike, T, ...

Four patients with collagen diseases are described, who developed protein losing enteropathy in the course of their disease. Their protein losing enteropathies subsided after treatment with 60 mg/day...

Changes in gastric acid secretion assayed by endoscopic gastrin test before and after Helicobacter pylori eradication

Iijima, K, Ohara, S, Sekine, H, Koike, T, Kato, K, Asaki, S, ...

BACKGROUND—It remains controversial whether or not Helicobacter pylori infection causes altered gastric acid secretion. A novel test for evaluating gastric acid secretion (endoscopic gastrin test;...

Helicobacter pylori infection prevents erosive reflux oesophagitis by decreasing gastric acid secretion

Koike, T, Ohara, S, Sekine, H, Iijima, K, Abe, Y, Kato, K, ...

BACKGROUND—Helicobacter pylori infection is less prevalent and atrophic gastritis is less extensive in patients with reflux oesophagitis than those without it, but few studies have examined this...

Up-regulated expression of Fas antigen (CD95) by peripheral naive and memory T cell subsets in patients with systemic lupus erythematosus (SLE): a possible mechanism for lymphopenia.

Amasaki, Y, Kobayashi, S, Takeda, T, Ogura, N, Jodo, S, Nakabayashi, T, ...

Fas antigen (CD95) is a membrane-associated molecule that mediates apoptotic cell death and may play a role in the induction and maintenance of T cell tolerance. To elucidate the involvement of Fas...

Murine leukaemia virus gene product as an acute phase protein: complete suppression of serum gp70 synthesis in hepatocytes of B10.S mice.

Shigemoto, K, Maruyama, N, Itoh, Y, Kubo, S, Koike, T

The Sgp-1c trait is associated with H-2s and relates to the small content of serum gp70 as well as the lack of serum gp70 responsiveness to lipopolysaccharide (LPS). Northern hybridization of RNA...

Anti-phospholipid antibodies and biological false positive serological test for syphilis in patients with systemic lupus erythematosus.

Koike, T, Sueishi, M, Funaki, H, Tomioka, H, Yoshida, S

Utilizing a newly developed solid phase enzyme immunoassay for the detection of anti-phospholipid antibodies, we found that 41.7% of sera from patients with active systemic lupus erythematosus (SLE)...

Specificity of mouse hybridoma antibodies to DNA. II. Phospholipid reactivity and biological false positive serological test for syphilis.

Koike, T, Maruyama, N, Funaki, H, Tomioka, H, Yoshida, S

Using mouse hybridoma monoclonal antibodies to DNA from MRL/lpr and NZB X NZW (B/W F1) mice, the reactivity of anti-DNA antibodies to several phospholipids was analysed. The anti-DNA antibody which...

Antibodies cross-reactive with DNA and cardiolipin in patients with systemic lupus erythematosus

Koike, T., Tomioka, H., Kumagai, A.

Using a modified solid phase radioimmunoassay (RIA), sera from 11 patients with systemic lupus erythematosus (SLE) that had high DNA binding activities were analysed for their ability to cross-react...

Monoclonal hybridoma anti-cardiolipin antibodies from SLE mice.

Ichikawa, K, Shimada, K, Nawata, Y, Ishii, T, Tomioka, H, Yoshida, S, ...

To determine whether the anti-cardiolipin antibodies are identical with the lupus anticoagulant and other antibodies to phospholipids and DNA, we prepared monoclonal hybridoma autoantibodies to...

Induction of endogenous retroviral gene product (SU) as an acute-phase protein by IL-6 in murine hepatocytes.

Itoh, Y, Maruyama, N, Kitamura, M, Shirasawa, T, Shigemoto, K, Koike, T

The effect of Lps locus and IL-6 on the production of SU (previously termed gp70), a mouse endogenous retroviral gene product, was studied. Back-cross studies using the progeny between (NZB x...

Short-term administration of anti-L3T4 MoAb prevents diabetes in NOD mice.

Kurasawa, K, Sakamoto, A, Maeda, T, Sumida, T, Ito, I, Tomioka, H, ...

We treated 2-week-old and 8-week-old non-obese diabetic (NOD) mice with 1 mg of anti-L3T4 MoAb weekly for 4 weeks. This short-term treatment of anti-L3T4 MoAb prevented the development of overt...

Expression of anticardiolipin cofactor, human beta 2-glycoprotein I, by a recombinant baculovirus/insect cell system.

Igarashi, M, Matsuura, E, Igarashi, Y, Nagae, H, Matsuura, Y, Ichikawa, K, ...

A full-length cDNA coding a human beta 2-glycoprotein I (beta 2-GPI) was introduced into the baculovirus genome to construct a recombinant baculovirus. Spodoptera frugiperda (Sf9) cells were infected...

Specificity of mouse hybridoma antibodies to DNA. III. Antigenic determinants of nucleic acids recognized by poly(dG) specific monoclonal antibodies.

Koike, T, Maruyama, N, Tomioka, H, Yoshida, S

Immunochemical properties of monoclonal autoantibodies to single stranded DNA (ssDNA), which were derived from systemic lupus erythematosus (SLE) prone mice and were specific for poly(dG), were...

Anti-IgE autoantibody in patients with bronchial asthma.

Nawata, Y, Koike, T, Yanagisawa, T, Iwamoto, I, Itaya, T, Yoshida, S, ...

The anti-IgE autoantibody in the IgG class was detected in 95.5% of patients with atopic asthma, and in 72.2% of those with non-atopic asthma, using a newly established solid phase enzyme immunoassay...

Serum levels of soluble Fas/APO-1 (CD95) and its molecular structure in patients with systemic lupus erythematosus (SLE) and other autoimmune diseases

JODO, S, KOBAYASHI, S, KAYAGAKI, N, OGURA, N, FENG, Y, AMASAKI, Y, ...

There are two major forms of the Fas molecule, membranous Fas and soluble Fas (sFas). To clarify the clinical significance of sFas in autoimmune diseases, we designed a sandwich ELISA to determine...

Oxidized low-density lipoprotein (Ox-LDL) but not LDL aggravates the manifestations of experimental antiphospholipid syndrome (APS)

GEORGE, J, BLANK, M, HOJNIK, M, BAR-MEIR, E, KOIKE, T, MATSUURA, E, ...

Ox-LDL is thought to play a major role in atherogenesis. The mechanisms mediating the deleterious influences of Ox-LDL include foam cell formation and cell cytotoxicity. The production of anti-Ox-LDL...

Elevated serum levels of soluble Fas/APO-1 (CD95) in patients with hepatocellular carcinoma

Jodo, S, Kobayashi, S, Nakajima, Y, Matsunaga, T, Nakayama, N, Ogura, N, ...

Fas (APO-1/CD95)-mediated apoptosis plays an important role in liver cell destruction in viral hepatitis. Using sandwich ELISA, we measured serum levels of soluble Fas (sFas) in patients with...

Binding of anticardiolipin antibodies to protein C via β2-glycoprotein I (β2-GPI): a possible mechanism in the inhibitory effect of antiphospholipid antibodies on the protein C system

Atsumi, T, Khamashta, M A, Amengual, O, Donohoe, S, Mackie, I, Ichikawa, K, ...

It is known that antiphospholipid antibodies (aPL) hamper the anticoagulant activity of the protein C system, but the mechanism is still obscure. In this study, we demonstrate that anticardiolipin...

Anti-idiotype immunomodulation of experimental anti-phospholipid syndrome via effect on Th1/Th2 expression

KRAUSE, I, BLANK, M, LEVI, Y, KOIKE, T, BARAK, V, SHOENFELD, Y

Mice with experimental anti-phospholipid syndrome (APS), induced by active immunization with a human anti-cardiolipin MoAb (H-3), were treated with mouse anti-idiotypic MoAb (anti-H3, named S2.9) and...

Detection of ‘antiphospholipid’ antibodies: a single chromogenic assay of thrombin generation sensitively detects lupus anticoagulants, anticardiolipin antibodies, plus antibodies binding β2-glycoprotein I and prothrombin

Sheng, Y, Hanly, J G, Reddel, S W, Kouts, S, Guerin, J, Koike, T, ...

The diagnosis of the antiphospholipid syndrome (APS) requires both a typical clinical event plus a persistently positive test in an assay for either anticardiolipin (aCL) antibodies or a lupus...

Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo.

Takeuchi, M., Makita, Z., Bucala, R., Suzuki, T., Koike, T., Kameda, Y.

BACKGROUND: The Maillard reaction that leads to the formation of advanced glycation end-products (AGE) plays an important role in the pathogenesis of angiopathy in diabetic patients and in the aging...

Detection of noncarboxymethyllysine and carboxymethyllysine advanced glycation end products (AGE) in serum of diabetic patients.

Takeuchi, M., Makita, Z., Yanagisawa, K., Kameda, Y., Koike, T.

BACKGROUND: The advanced stage of the Maillard reaction, which leads to the formation of advanced glycation end products (AGE), plays an important role in the pathogenesis of angiopathy in diabetic...

The polymorphism interleukin 8 −251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population

Ohyauchi, M, Imatani, A, Yonechi, M, Asano, N, Miura, A, Iijima, K, ...

Background: Helicobacter pylori infection is associated with variable clinical outcomes, including gastroduodenal diseases, and genetic factors may be relevant in this process.

Rebamipide, a Cytoprotective Drug, Increases Gastric Mucus Secretion in Human: Evaluations with Endoscopic Gastrin Test

Iijima, Katsunori, Ichikawa, T., Okada, S., Ogawa, M., Koike, T., Ohara, S., ...

We have previously developed a rapid, simple endoscopic method for evaluating gastrin-stimulated maximal acid output (the endoscopic gastrin test, EGT). In EGT, gastric fluid newly secreted over...

A randomised phase II trial of preoperative chemotherapy of cisplatin–docetaxel or docetaxel alone for clinical stage IB/II non-small-cell lung cancer: results of a Japan Clinical Oncology Group trial (JCOG 0204)

Kunitoh, H, Kato, H, Tsuboi, M, Asamura, H, Tada, H, Nagai, K, ...

Preoperative chemotherapy is a promising strategy in patients with early-stage resectable non-small-cell lung cancer (NSCLC); optimal chemotherapy remains unclear. Clinical (c-) stage IB/II NSCLC...