T. Laethem

THE PHARMACOKINETICS, SAFETY, AND TOLERABILITY OF TELCAGEPANT, A NOVEL CALCITONIN GENE RELATED PEPTIDE (CGRP) RECEPTOR ANTAGONIST, IN HEALTHY SUBJECTS AND MIGRAINEURS (2009)

Han, T H, Blanchard, R L, Palcza, J, De Lepeleire, I, Laethem, T, Martucci, A, ...

Multiple-dose pharmacodynamics and pharmacokinetics of Anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects (2008)

Krishna, R, Bergman, A, Jin, B, Fallon, M, Cote, J, Van Hoydonck, P, ...

Cholesteryl ester transfer protein (CETP) is a plasma protein that catalyzes the heteroexchange of cholesteryl esters from high-density lipoprotein (HDL) and trglycerides to apolipoprotein...

The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers (2007)

Van Hecken, Anne; U0011994, De Lepeleire, I, Thach, C, Oeyen, M, Van Effen, J, ...

INTRODUCTION: Nasal congestion in allergic rhinitis results from tissue edema and vasodilatation in the nasal mucosa. Of the mediators released by mast cells in response to allergens, prostaglandin...

Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin (2005)

Oeyen, M, De Lepeleire, I, Laethem, T, Rothenberg, P, ...

OBJECTIVE: To examine the effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin. Aprepitant is a neurokinin-1 (NK1)-receptor antagonist developed as an antiemetic for...

Effect of Aprepitant on the Pharmacokinetics and Pharmacodynamics of Warfarin (2005)

Oeyen, Marc, De Lepeleire, Inge, Laethem, T., Rothenberg, P., ...

Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin (2004)

Oeyen, M, De Lepeleire, I, Laethem, T, Rothenberg, P, ...

Desirudin: effect on blood coagulation tests in vitro and following a subcutaneous administration in healthy volunteers (2002)

De Lepeleire, I, Laethem, T, ...

[11C]Flumazenil kinetic analysis using image-derived input function (2002)

Maes, Alex; U0032501, De Groot, T, Coimbra, A, ...

Tissue Penetration by Ertapenem, a Parenteral Carbapenem Administered Once Daily, in Suction-Induced Skin Blister Fluid in Healthy Young Volunteers

Laethem, T., De Lepeleire, I., McCrea, J., Zhang, J., Majumdar, A., Musson, D., ...

The penetration of 1 g of intravenous ertapenem once daily for 3 days in suction-induced skin blisters was evaluated. Ten forearm blisters were formed (n = 12) 12 h prior to the last dose....

Tissue Penetration by Ertapenem, a Parenteral Carbapenem Administered Once Daily, in Suction-Induced Skin Blister Fluid in Healthy Young Volunteers

Laethem, T., De Lepeleire, I., McCrea, J., Zhang, J., Majumdar, A., Musson, D., ...

The penetration of 1 g of intravenous ertapenem once daily for 3 days in suction-induced skin blisters was evaluated. Ten forearm blisters were formed (n = 12) 12 h prior to the last dose....

Desirudin: effect on blood coagulation tests in vitro and following a subcutaneous administration in healthy volunteers

Van Hecken, A, Depré, M, Verbesselt, R, Arnout, J, De Lepeleire, I, Laethem, T, ...