T. M. Saxton

Evidence for a functional subclass of the RTVL-H family of human endogenous retrovirus-like sequences.

Wilkinson, D A, Goodchild, N L, Saxton, T M, Wood, S, Mager, D L

We report the discovery of a subgroup of RTVL-H human endogenous retroviral elements, designated RTVL-Hp, that is intact in the pol region which is deleted in the vast majority of RTVL-H elements. As...

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

Saxton, T M, Henkemeyer, M, Gasca, S, Shen, R, Rossi, D J, Shalaby, F, ...

Shp-1, Shp-2 and corkscrew comprise a small family of cytoplasmic tyrosine phosphatases that possess two tandem SH2 domains. To investigate the biological functions of Shp-2, a targeted mutation has...

Evidence for a functional subclass of the RTVL-H family of human endogenous retrovirus-like sequences.

Wilkinson, D A, Goodchild, N L, Saxton, T M, Wood, S, Mager, D L

We report the discovery of a subgroup of RTVL-H human endogenous retroviral elements, designated RTVL-Hp, that is intact in the pol region which is deleted in the vast majority of RTVL-H elements. As...

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

Saxton, T M, Henkemeyer, M, Gasca, S, Shen, R, Rossi, D J, Shalaby, F, ...

Shp-1, Shp-2 and corkscrew comprise a small family of cytoplasmic tyrosine phosphatases that possess two tandem SH2 domains. To investigate the biological functions of Shp-2, a targeted mutation has...