DOUGLAS, T. C., MEO, T., SKARVALL, H.
Males of a partially inbred mouse stock homozygous for cw and d were crossed to AKR/ABom females. Progeny obtained by backcrossing heterozygous F1 females to cw dlcw d males were analyzed for the...
Shreffler, Donald C., Young, H., Nabholz, M., Meo, T., Rijnbeek, A., Miggiano, V.
B6.C-H-2 ba [H (z1)] is a mutant derived from C57BL/6. The two strains mutually reject their skingrafts and are incompatible in the mixed leucocyte reaction (MLR) and in cell-mediated lympholysis...
Male-specific transcription initiation of the C4-Slp gene in mouse liver follows activation of STAT5
Varin-Blank, N., Dondi, E., Tosi, M., Hernandez, C., Boucontet, L., Gotoh, H., ...
The mouse genes encoding the constitutively expressed complement component C4 and its closely related isoform C4-Slp (sex-limited protein), which is expressed only in male animals of several strains,...
Efficient detection of point mutations on color-coded strands of target DNA.
Verpy, E, Biasotto, M, Meo, T, Tosi, M
Presently available methods for screening large genetic regions for unknown point mutations are neither flawless nor particularly efficient. We describe an approach, especially well suited to...
Male-specific expression of mouse sex-limited protein requires growth hormone, not testosterone.
Georgatsou, E, Bourgarel, P, Meo, T
Sex-limited protein (Slp), an isoform of mouse complement component C4, is expressed predominantly in liver and nearly exclusively in sexually mature males or testosterone-treated females. It is...
The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.
Miyagoe, Y, Georgatsou, E, Varin-Blank, N, Meo, T
The androgen-dependent liver protein Slp, together with its constitutively expressed closely related isoform C4, provides a model to address the question of which minimal alteration in DNA can shut...
Gaspar, M L, Meo, T, Bourgarel, P, Guenet, J L, Tosi, M
Testosterone-resistant male mice hemizygous for the X-chromosome-linked mutant gene Tfm express detectable but severely reduced levels of androgen receptor mRNA, amounting to about 10% of the level...
Stoppa-Lyonnet, D, Carter, P E, Meo, T, Tosi, M
Frequent alterations in the structure of the complement component C1 inhibitor gene have been found in patients affected by the common variant of hereditary angioedema, characterized by low plasma...
The Wu-Kabat variability coefficient is a well-established descriptor of the susceptibility of an amino acid position to evolutionary replacements. It conveniently highlights stretches of accentuated...
cDNA cloning of the immunoglobulin heavy chain binding protein.
A cDNA library was constructed from size-fractionated poly(A)+ RNA prepared from a murine pre-B-cell hybridoma expressing high levels of immunoglobulin heavy chain binding protein (BiP) and mu heavy...
Verpy, E, Couture-Tosi, E, Eldering, E, Lopez-Trascasa, M, Späth, P, Meo, T, ...
The last exon of the C1-1NH gene was screened for point mutations in 36 unrelated hereditary angioedema patients. Mutations were found in eight patients, predicting changes in the short COOH-terminal...
Szöts, H, Riethmüller, G, Weiss, E, Meo, T
Antigen HLA-B27 is a high-risk genetic factor with respect to a group of rheumatoid disorders, especially ankylosing spondylitis. A cDNA library was constructed from an autozygous B-cell line...
Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse.
Hengartner, H, Meo, T, Müller, E
Using somatic cell hybrids from fusions of lymphocytes of two different mouse stocks with the myeloma cell line X63-Ag8, we have assigned genes for the immunoglobulin heavy and kappa-type light...
Monoclonal antibodies to human urokinase identify the single-chain pro-urokinase precursor.
Salerno, G, Verde, P, Nolli, M L, Corti, A, Szöts, H, Meo, T, ...
Monoclonal antibodies have been obtained that recognize either the A or B chain of human urinary urokinase. These antibodies identify human urokinase-producing cells and the product of urokinase...
Meo, T, Johnson, J, Beechey, C V, Andrews, S J, Peters, J, Searle, A G
Analysis of backcross mice carrying the Harwell translocation T(5;12)31H has led to the definitive localization of the immunoglobulin heavy chain gene cluster. Both Igh-1 and Pre-1 loci were found to...
Wabl, M R, Johnson, J P, Haas, I G, Tenkhoff, M, Meo, T, Inan, R
A hamster-mouse hybrid cell line expressiong both murine IgM and murine IgD on the membrane was shown to have only one copy of mouse chromosome 12. This chromosome is known to carry the structural...
Dausset, J., Contu, L., Legrand, L., Marcelli-Barge, A., Meo, T., Rapaport, F. T.
This report correlates the survival time of 93 intrafamilial skin allografts performed under conditions of main histocompatibility complex (HLA) haploidentity with donor-recipient compatibility for...
Meo, T, Krasteff, T, Shreffler, D C
The S region of the mouse H-2 complex is genetically defined by a series of alleles, or pseudoalleles, which control the level of a serum globulin, Ss, and of its allotypic vairatn, Slp. In contrast...
Amor, M, Tosi, M, Duponchel, C, Steinmetz, M, Meo, T
A search for uncharacterized genes of the S region of the murine H-2 major histocompatibility complex was undertaken; a series of cosmid clones previously aligned by overlap hybridizations were used...
Meo, T, Gramsch, C, Inan, R, Höllt, V, Weber, E, Herz, A, ...
Six myeloma cell hybrids producing antibodies to human beta-endorphin were isolated from a single mouse spleen. The monoclonal antibodies displayed different binding patterns with the antigen. We...
Levi-Strauss, M, Tosi, M, Steinmetz, M, Klein, J, Meo, T
Mouse liver cDNA clones related to the C4 and C4-Slp isoforms of the fourth component of complement differ by few nucleotide changes within a region of substantial divergence from human C4. It is...
Meo, T, Atkinson, J P, Bernoco, M, Bernoco, D, Ceppellini, R
A zymogram method, following thin-layer isoelectric focusing in a polyacrylamide gel, allows resolution of the lytic activity of serum C2 complement protein in a spectrum of molecular forms. This...
The mouse mammary tumour virus long terminal repeat encodes a type II transmembrane glycoprotein.
Korman, A J, Bourgarel, P, Meo, T, Rieckhof, G E
Superantigens are products of bacterial or viral origin which stimulate large numbers of T cells as a consequence of the interaction of particular V beta chains of the T cell receptor with class II...
Male-specific transcription initiation of the C4-Slp gene in mouse liver follows activation of STAT5
Varin-Blank, N., Dondi, E., Tosi, M., Hernandez, C., Boucontet, L., Gotoh, H., ...
The mouse genes encoding the constitutively expressed complement component C4 and its closely related isoform C4-Slp (sex-limited protein), which is expressed only in male animals of several strains,...
Efficient detection of point mutations on color-coded strands of target DNA.
Verpy, E, Biasotto, M, Meo, T, Tosi, M
Presently available methods for screening large genetic regions for unknown point mutations are neither flawless nor particularly efficient. We describe an approach, especially well suited to...
Male-specific expression of mouse sex-limited protein requires growth hormone, not testosterone.
Georgatsou, E, Bourgarel, P, Meo, T
Sex-limited protein (Slp), an isoform of mouse complement component C4, is expressed predominantly in liver and nearly exclusively in sexually mature males or testosterone-treated females. It is...
The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.
Miyagoe, Y, Georgatsou, E, Varin-Blank, N, Meo, T
The androgen-dependent liver protein Slp, together with its constitutively expressed closely related isoform C4, provides a model to address the question of which minimal alteration in DNA can shut...
Gaspar, M L, Meo, T, Bourgarel, P, Guenet, J L, Tosi, M
Testosterone-resistant male mice hemizygous for the X-chromosome-linked mutant gene Tfm express detectable but severely reduced levels of androgen receptor mRNA, amounting to about 10% of the level...
Stoppa-Lyonnet, D, Carter, P E, Meo, T, Tosi, M
Frequent alterations in the structure of the complement component C1 inhibitor gene have been found in patients affected by the common variant of hereditary angioedema, characterized by low plasma...
The Wu-Kabat variability coefficient is a well-established descriptor of the susceptibility of an amino acid position to evolutionary replacements. It conveniently highlights stretches of accentuated...
cDNA cloning of the immunoglobulin heavy chain binding protein.
A cDNA library was constructed from size-fractionated poly(A)+ RNA prepared from a murine pre-B-cell hybridoma expressing high levels of immunoglobulin heavy chain binding protein (BiP) and mu heavy...
Verpy, E, Couture-Tosi, E, Eldering, E, Lopez-Trascasa, M, Späth, P, Meo, T, ...
The last exon of the C1-1NH gene was screened for point mutations in 36 unrelated hereditary angioedema patients. Mutations were found in eight patients, predicting changes in the short COOH-terminal...
Szöts, H, Riethmüller, G, Weiss, E, Meo, T
Antigen HLA-B27 is a high-risk genetic factor with respect to a group of rheumatoid disorders, especially ankylosing spondylitis. A cDNA library was constructed from an autozygous B-cell line...
Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse.
Hengartner, H, Meo, T, Müller, E
Using somatic cell hybrids from fusions of lymphocytes of two different mouse stocks with the myeloma cell line X63-Ag8, we have assigned genes for the immunoglobulin heavy and kappa-type light...
Monoclonal antibodies to human urokinase identify the single-chain pro-urokinase precursor.
Salerno, G, Verde, P, Nolli, M L, Corti, A, Szöts, H, Meo, T, ...
Monoclonal antibodies have been obtained that recognize either the A or B chain of human urinary urokinase. These antibodies identify human urokinase-producing cells and the product of urokinase...
Meo, T, Johnson, J, Beechey, C V, Andrews, S J, Peters, J, Searle, A G
Analysis of backcross mice carrying the Harwell translocation T(5;12)31H has led to the definitive localization of the immunoglobulin heavy chain gene cluster. Both Igh-1 and Pre-1 loci were found to...
Wabl, M R, Johnson, J P, Haas, I G, Tenkhoff, M, Meo, T, Inan, R
A hamster-mouse hybrid cell line expressiong both murine IgM and murine IgD on the membrane was shown to have only one copy of mouse chromosome 12. This chromosome is known to carry the structural...
Dausset, J., Contu, L., Legrand, L., Marcelli-Barge, A., Meo, T., Rapaport, F. T.
This report correlates the survival time of 93 intrafamilial skin allografts performed under conditions of main histocompatibility complex (HLA) haploidentity with donor-recipient compatibility for...
Meo, T, Krasteff, T, Shreffler, D C
The S region of the mouse H-2 complex is genetically defined by a series of alleles, or pseudoalleles, which control the level of a serum globulin, Ss, and of its allotypic vairatn, Slp. In contrast...
Amor, M, Tosi, M, Duponchel, C, Steinmetz, M, Meo, T
A search for uncharacterized genes of the S region of the murine H-2 major histocompatibility complex was undertaken; a series of cosmid clones previously aligned by overlap hybridizations were used...
Meo, T, Gramsch, C, Inan, R, Höllt, V, Weber, E, Herz, A, ...
Six myeloma cell hybrids producing antibodies to human beta-endorphin were isolated from a single mouse spleen. The monoclonal antibodies displayed different binding patterns with the antigen. We...
Levi-Strauss, M, Tosi, M, Steinmetz, M, Klein, J, Meo, T
Mouse liver cDNA clones related to the C4 and C4-Slp isoforms of the fourth component of complement differ by few nucleotide changes within a region of substantial divergence from human C4. It is...
Meo, T, Atkinson, J P, Bernoco, M, Bernoco, D, Ceppellini, R
A zymogram method, following thin-layer isoelectric focusing in a polyacrylamide gel, allows resolution of the lytic activity of serum C2 complement protein in a spectrum of molecular forms. This...
The mouse mammary tumour virus long terminal repeat encodes a type II transmembrane glycoprotein.
Korman, A J, Bourgarel, P, Meo, T, Rieckhof, G E
Superantigens are products of bacterial or viral origin which stimulate large numbers of T cells as a consequence of the interaction of particular V beta chains of the T cell receptor with class II...
Verpy, E., Biasotto, M., Brai, M., Misiano, G., Meo, T., Tosi, M.
A complete mutational scan of the gene coding for the serpin C1 inhibitor, comprising all eight exons and adjacent intron sequences and 550 bp preceding the transcription start site, was rapidly...
Johnson, JP, Meo, T, Reithmuller, G, Schendel, DJ, Wank, R
A murine monoclonal antibody directed against a human B cell surface antigen with the characteristics of HLA-DR is described. The antigen detected is tightly linked to HLA and is correlated with the...