T. Mitera

Activated CD4+CD25+ regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis (2008)

Kelchtermans, K, Geboes, L, Mitera, T, Huskens, D, Leclercq, Georges, Matthys, P

OBJECTIVES: Patients with rheumatoid arthritis (RA) have defective CD4(+)CD25(+) regulatory T (T(reg)) cells and increased osteoclastogenesis. A similar situation has been described in...

Defective CD4(+)CD25(+) regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma (2005)

Kelchtermans, H, De Klerck, B, Mitera, T, Van Balen, M, Bullens, D, Billiau, A, ...

Mice with a deficiency in IFN-gamma or IFN-gamma receptor (IFN-gamma R) are more susceptible to collagen-induced arthritis (CIA), an experimental autoimmune disease that relies on the use of complete...

Defective CD4(+)CD25(+) regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma (2005)

KELCHTERMANS, H, DE KLERCK, B, MITERA, T, VAN BALEN, M, BULLENS, D, BILLIAU, A, ...

Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo (2002)

Dooms, H, Rottiers, P, Mitera, T, Overgergh, L, Leclercq, G, ...

TCR/CD3 aggregation by injection of anti-CD3 Ab produces T cell activation, release of cytokines such as IFN-gamma, and apoptosis in the cortical region of the thymus. We show that anti-CD3 Ab...

Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo. (2002)

MATTHYS, P, Dooms, Hans, Rottiers, Pieter, MITERA, T, OVERBERGH, L, Leclercq, Georges, ...

Enhanced autoimmune arthritis in IFN-gamma receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells (1999)

Mitera, T, Huang, S, ...

Induction of experimental autoimmune diseases often relies on immunization with the organ-specific autoantigens in CFA, which contains heat-killed mycobacteria. In several of these models, including...

Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice (1998)

Mitera, T, Huang, S

In several models of inflammation, including collagen-induced arthritis (CIA), the disease-promoting effect of IL-12 has been attributed to its well-known ability to produce IFN-gamma. However,...

Cloning, bacterial expression and biological characterization of recombinant human granulocyte chemotactic protein-2 and differential expression of granulocyte chemotactic protein-2 and epithelial cell-derived neutrophil activating peptide-78 mRNAs (1997)

Ronsse, I, Mitera, T, ...

Human osteosarcoma cells secrete a novel C-X-C chemokine called granulocyte chemotactic protein-2 (GCP-2), which was previously identified by amino acid sequencing of the purified natural protein. In...

Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice (1995)

Mitera, T

Administration of staphylococcal enterotoxin B (SEB) to BALB/c mice was found to induce a cytokine release syndrome hallmarked by weight loss and hypoglycemia. A neutralizing monoclonal antibody...

Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice.

Matthys, P, Mitera, T, Heremans, H, Van Damme, J, Billiau, A

Administration of staphylococcal enterotoxin B (SEB) to BALB/c mice was found to induce a cytokine release syndrome hallmarked by weight loss and hypoglycemia. A neutralizing monoclonal antibody...

Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice.

Matthys, P, Mitera, T, Heremans, H, Van Damme, J, Billiau, A

Administration of staphylococcal enterotoxin B (SEB) to BALB/c mice was found to induce a cytokine release syndrome hallmarked by weight loss and hypoglycemia. A neutralizing monoclonal antibody...

Induction of IL-15 by TCR/CD3 aggregation depends on IFN-γ and protects against apoptosis of immature thymocytes in vivo

Matthys, P, DOOMS, H, ROTTIERS, P, MITERA, T, OVERGERGH, L, LECLERCQ, G, ...

TCR/CD3 aggregation by injection of anti-CD3 Ab produces T cell activation, release of cytokines such as IFN-γ, and apoptosis in the cortical region of the thymus. We show that anti-CD3 Ab induces...