Introduction 1 THE PDB AND THE CHALLENGE OF STRUCTURAL GENOMICS (2007)
Helen M Berman, T. N. Bhat, Philip E. Bourne, Zukang Feng, Gary Gillil, Helge Weissig, ...
1 THE PDB DATA UNIFORMITY PROJECT (2007)
T. N. Bhat, Philip Bourne, Zukang Feng, Gary Gillil, Shri Jain, Bohdan Schneider, ...
The Protein Data Bank (PDB;
John Westbrook, Zukang Feng, Shri Jain, T. N. Bhat, Narmada Thanki, Veerasamy Ravichandran, ...
The Protein Data Bank (PDB;
Tammy Battistuz, T. N. Bhat, Philip E, Phoebe Fagan, Jessica Marvin, David Padilla, ...
Copyright © International Union of Crystallography Author(s) of this paper may load this reprint on their own web site provided that this cover page is retained. Republication of this article or its...
T. N. Bhat, Philip Bourne, Zukang Feng, Gary Gilliland, Bohdan Schneider, Kata Schneider, ...
and Helen M. Berman
A framework for scientific data modeling and automated software development (2005)
Fogh, Rasmus H., Boucher, Wayne, Vranken, Wim F., Pajon, Anne, Stevens, Tim J., Bhat, T. N., ...
Motivation: The lack of standards for storage and exchange of data is a serious hindrance for the large-scale data deposition, data mining and program interoperability that is becoming increasingly...
A framework for scientific data modeling and automated software development (2004)
Fogh, Rasmus H., Boucher, Wayne, Vranken, Wim F., Pajon, Anne, Stevens, Tim J., Bhat, T. N., ...
Motivation: The lack of standards for storage and exchange of data is a serious hindrance for the large-scale data deposition, data mining and program interoperability that is becoming increasingly...
A framework for scientific data modeling and automated software development (2004)
Fogh, Rasmus H., Boucher, Wayne, Vranken, Wim F., Pajon, Anne, Stevens, Tim J., Bhat, T. N., ...
Motivation: The lack of standards for storage and exchange of data is a serious hindrance for the large-scale data deposition, data mining and program interoperability that is becoming increasingly...
The Protein Data Bank: unifying the archive (2002)
Westbrook, John, Feng, Zukang, Jain, Shri, Bhat, T. N., Thanki, Narmada, Ravichandran, Veerasamy, ...
The Protein Data Bank (PDB; http://www.pdb.org/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the progress that has been made in...
The PDB data uniformity project (2001)
Bhat, T. N., Bourne, Philip, Feng, Zukang, Gilliland, Gary, Jain, Shri, Ravichandran, Veerasamy, ...
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the data uniformity project...
Berman, Helen M., Westbrook, John, Feng, Zukang, Gilliland, Gary, Bhat, T. N., Weissig, Helge, ...
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the...
The PDB data uniformity project
Bhat, T. N., Bourne, Philip, Feng, Zukang, Gilliland, Gary, Jain, Shri, Ravichandran, Veerasamy, ...
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the data uniformity project that is...
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
Silva, A M, Lee, A Y, Gulnik, S V, Maier, P, Collins, J, Bhat, T N, ...
Plasmodium falciparum is the major causative agent of malaria, a disease of worldwide importance. Resistance to current drugs such as chloroquine and mefloquine is spreading at an alarming rate, and...
Baldwin, E T, Bhat, T N, Gulnik, S, Hosur, M V, Sowder, R C, Cachau, R E, ...
Cathepsin D (EC 3.4.23.5) is a lysosomal protease suspected to play important roles in protein catabolism, antigen processing, degenerative diseases, and breast cancer progression. Determination of...
Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.
Chitarra, V, Alzari, P M, Bentley, G A, Bhat, T N, Eiselé, J L, Houdusse, A, ...
Although antibodies are highly specific, cross-reactions are frequently observed. To understand the molecular basis of this phenomenon, we studied the anti-hen egg lysozyme (HEL) monoclonal antibody...
The Protein Data Bank: unifying the archive
Westbrook, John, Feng, Zukang, Jain, Shri, Bhat, T. N., Thanki, Narmada, Ravichandran, Veerasamy, ...
The Protein Data Bank (PDB; http://www.pdb.org/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the progress that has been made in validating...
Berman, Helen M., Westbrook, John, Feng, Zukang, Gilliland, Gary, Bhat, T. N., Weissig, Helge, ...
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place...
Markowitz, M, Mo, H, Kempf, D J, Norbeck, D W, Bhat, T N, Erickson, J W, ...
Inhibitors of the human immunodeficiency virus protease represent a promising new class of antiretroviral drugs for the treatment of AIDS. We now report the in vitro selection of viral variants with...
Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Bhat, T N, Bentley, G A, Boulot, G, Greene, M I, Tello, D, Dall'Acqua, W, ...
We report the three-dimensional structures, at 1.8-A resolution, of the Fv fragment of the anti-hen egg white lysozyme antibody D1.3 in its free and antigen-bound forms. These structures reveal a...
The PDB data uniformity project
Bhat, T. N., Bourne, Philip, Feng, Zukang, Gilliland, Gary, Jain, Shri, Ravichandran, Veerasamy, ...
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the data uniformity project that is...
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
Silva, A M, Lee, A Y, Gulnik, S V, Maier, P, Collins, J, Bhat, T N, ...
Plasmodium falciparum is the major causative agent of malaria, a disease of worldwide importance. Resistance to current drugs such as chloroquine and mefloquine is spreading at an alarming rate, and...
Baldwin, E T, Bhat, T N, Gulnik, S, Hosur, M V, Sowder, R C, Cachau, R E, ...
Cathepsin D (EC 3.4.23.5) is a lysosomal protease suspected to play important roles in protein catabolism, antigen processing, degenerative diseases, and breast cancer progression. Determination of...
Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.
Chitarra, V, Alzari, P M, Bentley, G A, Bhat, T N, Eiselé, J L, Houdusse, A, ...
Although antibodies are highly specific, cross-reactions are frequently observed. To understand the molecular basis of this phenomenon, we studied the anti-hen egg lysozyme (HEL) monoclonal antibody...
The Protein Data Bank: unifying the archive
Westbrook, John, Feng, Zukang, Jain, Shri, Bhat, T. N., Thanki, Narmada, Ravichandran, Veerasamy, ...
The Protein Data Bank (PDB; http://www.pdb.org/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the progress that has been made in validating...
Berman, Helen M., Westbrook, John, Feng, Zukang, Gilliland, Gary, Bhat, T. N., Weissig, Helge, ...
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place...
Markowitz, M, Mo, H, Kempf, D J, Norbeck, D W, Bhat, T N, Erickson, J W, ...
Inhibitors of the human immunodeficiency virus protease represent a promising new class of antiretroviral drugs for the treatment of AIDS. We now report the in vitro selection of viral variants with...
Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Bhat, T N, Bentley, G A, Boulot, G, Greene, M I, Tello, D, Dall'Acqua, W, ...
We report the three-dimensional structures, at 1.8-A resolution, of the Fv fragment of the anti-hen egg white lysozyme antibody D1.3 in its free and antigen-bound forms. These structures reveal a...