Zhang, X. N., Lemmens, P., Nakajima, T., Ueda, Y.
We report on Raman scattering measurements of the A-site ordered YBaMn2O6 in the wide temperature range of 10-650K. Upon cooling almost all phonon modes show pronounced temperature dependencies of...
Okiyama, W, Tanaka, N, Nakajima, T, Tanaka, E, Kiyosawa, K, Gonzalez, FJ, ...
Background/Aims: Alcoholic liver disease (ALD) is one of the leading causes of cirrhosis and yet efficient therapeutic strategies are lacking. Polyenephosphatidylcholine (PPC), a major component of...
Evidence for large electric polarization from collinear magnetism in TmMnO3 (2009)
Pomjakushin, V. Yu., Kenzelmann, M., Donni, A., Harris, A. B., Nakajima, T., Mitsuda, S., ...
There has been tremendous research activity in the field of magneto-electric (ME) multiferroics after Kimura et al. [1] showed that antiferromagnetic and ferroelectric order coexist in orthorhom-...
Shudo, T, Nakajima, T, Hiraga, K
Palm oil has the important advantage of productivity compared with other vegetable oils such as rapeseed oil and soybean oil. However, the cold flow performance of palm oil methyl ester (PME) is...
Electron Spin Resonance across the Charge-ordering Transition in YBaMn2O6 (2008)
Zakharov, D., Deisenhofer, J., Nakajima, T., Ueda, Y., Loidl, A.
We investigated the metal-ordered manganite system YBaMn2O6 using electron spin resonance (ESR) in the paramagnetic regime across the charge-ordering and structural phase transition at T_CO = 480 K...
Nakajima, T, Tanaka, N, Sugiyama, E, Kamijo, Y, Hara, A, Hu, R, ...
Fifteen new T dwarfs discovered in the UKIDSS Large Area Survey (2008)
Pinfield, D. J., Burningham, B., Tamura, M., Leggett, S. K., Lodieu, N., Lucas, P. W., ...
We present the discovery of fifteen new T2.5-T7.5 dwarfs (with estimated distances between ~24-93pc, identified in the first three main data releases of the UKIRT Infrared Deep Sky Survey. This...
SEARCHES FOR $\beta$-ALANINE AND PYRIMIDINE TOWARD ORION-KL (2008)
Fujimori, R., Kawaguchi, K., Nakajima, T., Ogawa, H.
S. Watanebe, S. Kubota, K. Kawaguchi, Y. Kasai, and T. Momose, 61st V. B. Blagojevic, S. Petrie, and D. K. Bohme, Mon. Not. R. Astron. Soc.Y. J. Kuan, C. H. Yan, S. B. Charnley, Z. Kisiel, P....
Applicatication Of the Rhumb Line Control Strategy To The Highly Spinning Dash Orbiter (2007)
Y. Morita, J. Kawaguchi, T. Nakajima, H. Hinada, H. Terada
The paper reveals the essential feature of the attitude control system for the demonstrator of atmospheric reentry system with hyperbolic velocity (DASH) and evaluates its fundamental performance....
Ju Ne, K. Matthews, T. Nakajima, S. R. Kulkarni
Infrared broad-band photometry of the cool brown dwarf Gliese 229B extending in wavelength from 0.8 to 10.5 ¯m is reported. These results are derived from both new data and reanalyzed, previously...
Growth Mechanism and Selective Synthesis of SWNTs (2007)
Inoue, S., Nakajima, T., Nomura, K., Kikuchi, Y.
Ever since the landmark discovery of single-walled carbon nanotubes (SWNTs) in 1993, they have been considered as ideal materials for any kind of application based on their outstanding properties...
Nakajima, T., Mitsuda, S., Kanetsuki, S., Tanaka, K., Fujii, K., Terada, N., ...
Multiferroic CuFe1-xAlxO2 (x=0.02) exhibits a ferroelectric ordering accompanied by a proper helical magnetic ordering below T=7K under zero magnetic field. By polarized neutron diffraction and...
Two T dwarfs from the UKIDSS Early Data Release (2007)
Kendall, T. R., Tamura, M., Tinney, C. G., Martin, E. L., Ishii, M., Pinfield, D. J., ...
We report on the first ultracool dwarf discoveries from the UKIRT Infrared Deep Sky Survey (UKIDSS) Large Area Survey Early Data Release (LAS EDR), in particular the discovery of T dwarfs which are...
Peroxisome proliferator-activated receptor α-independent peroxisome proliferation (2006)
Zhang, XG, Tanaka, N, Nakajima, T, Kamijo, Y, Gonzalez, FJ, Aoyama, T
Hepatic peroxisome proliferation, increases in the numerical and volume density of peroxisomes, is believed to be closely related to peroxisome proliferator-activated receptor α (PPARα) activation;...
Growth Mechanism and Selective Synthesis of SWNTs (2006)
Inoue, S., Nakajima, T., Nomura, K., Kikuchi, Y.
Ever since the landmark discovery of single-walled carbon nanotubes (SWNTs) in 1993, they have been considered as ideal materials for any kind of application based on their outstanding properties...
Growth Mechanism and Selective Synthesis of SWNTs (2006)
Inoue, S., Nakajima, T., Nomura, K., Kikuchi, Y.
Ever since the landmark discovery of single-walled carbon nanotubes (SWNTs) in 1993, they have been considered as ideal materials for any kind of application based on their outstanding properties...
Kawasaki, Y., Minami, T., Kishimoto, Y., Ohno, T., Zenmyo, K., Kubo, H., ...
$^{139}$La- and $^{55}$Mn-NMR spectra demonstrate that the ground state of the A-site ordered perovskite manganite LaBaMn$_2$O$_6$ is a spatial mixture of the ferromagnetic (FM) and antiferromagnetic...
Pimentel, C, Chagot, B, Gilles, N, ...
Delta-paluIT1 and delta-paluIT2 are toxins purified from the venom of the spider Paracoelotes luctuosus. Similar in sequence to mu-agatoxins from Agelenopsis aperta, their pharmacological target is...
Dai, L, Pil, J, Nakajima, T, Corzo, G, ...
The Om-toxins are short peptides (23-27 amino acids) purified from the venom of the scorpion Opisthacanthus madagascariensis. Their pharmacological targets are thought to be potassium channels. Like...
Application of an Insoluble Hageman Factor Complex to Kinin Research. (2005)
Nakajima,T., Seki,T., Erdoes,E. G.
A water-insoluble complex of prekallikrein activator was prepared by adsorbing Hageman factor (factor XII) on diatomaceous earth and cross-linking it with glutaraldehyde. The preparation initiated...
A coronagraphic search for brown dwarfs and planets around nearby stars (2005)
Nakajima, T., Morino, J. I., Tsuji, T., Suto, H., Ishii, M., Tamura, M., ...
Yamazaki, K, Honda, T, Oda, T, Ueki-Maruyama, K, Nakajima, T, Yoshie, H, ...
Background: Recent epidemiological studies have shown that individuals with periodontitis have a significantly increased risk of developing coronary heart disease. In addition to conventional risk...
Regulatory T-cells infiltrate periodontal disease tissues (2005)
Nakajima, T, Ueki-Maruyama, K, Oda, T, Ohsawa, Y, Ito, H, Seymour, GJ, ...
CD4(+) CD25(+) regulatory T ( Tr) cells are critical in regulating the immune response and thereby play an important role in the defense against infection and control of autoimmune diseases. Our...
Progesterone induces the fibulin-1 expression in human endometrial stromal cells (2005)
Nakamoto, T., Okada, H., Nakajima, T., Ikuta, A., Yasuda, K., Kanzaki, H.
BACKGROUND: By using microarray analysis with human endometrial stromal cells (ESCs), we previously reported that the mRNA for fibulin-1, an extracellular matrix as well as a plasma glycoprotein, is...
Progesterone induces the fibulin-1 expression in human endometrial stromal cells (2005)
Nakamoto, T., Okada, H., Nakajima, T., Ikuta, A., Yasuda, K., Kanzaki, H.
BACKGROUND: By using microarray analysis with human endometrial stromal cells (ESCs), we previously reported that the mRNA for fibulin-1, an extracellular matrix as well as a plasma glycoprotein, is...
ASEPS-0 Testbed Interferometer (2004)
Colavita, M., Shao, M., Hines, B., Wallace, J., Gursel, Y., Malbet, F., ...
The ASEPS-0 Testbed Interferometer is a long-baseline infrared interferometer optimized for high-accuracy narrow-angle astrometry.
Hyper-ERAD: a novel pathomechanism for rheumatoid arthritis (2004)
Nakajima, T, Yagishita, N, Yamasaki, S, Tsuchimochi, K, Amano, T, Fukamizu, A, ...
No abstract available.
Observation of two-photon above-threshold ionization of rare gases by xuv harmonic photons (2004)
Miyamoto, N, Kamei, M, Yoshitomi, D, Kanai, T, Sekikawa, T, Nakajima, T, ...
Nakajima, T., Yoshizawa, H., Ueda, Y.
The discovery of novel structural and physical properties in the $A$-site ordered manganite $R$BaMn$_{2}$O$_{6}$ ($R$ = Y and rare earth elements) has demanded new comprehension about perovskite...
Effect of Endotoxin on AV Conductivity in the Dog (2004)
Using constant flow perfusion from 4 to 6 ml/min of the AV node artery, the effect of endotoxin was investigated in six vagotomized dogs in situ. All preparations demonstrated AV block following...
Toyo-Oka, T., Kawada, T., Nakata, J., Xie, H., Urabe, M., Masui, F., ...
Toyo-Oka, T., Kawada, T., Nakata, J., Xie, H., Urabe, M., Masui, F., ...
Yamazaki, K, Ohsawa, Y, Itoh, H, Ueki, K, Tabeta, K, Oda, T, ...
Individuals with periodontitis have been reported to have a significantly increased risk of developing coronary heart disease. Several studies have demonstrated that the immune response to heat shock...
Effect of periodontal treatment on the serum antibody levels to heat shock proteins (2004)
Yamazaki, K, Ueki-Maruayama, K, Honda, T, Nakajima, T, Seymour, GJ
We have shown previously that both humoral and cellular immune responses to heat shock protein 60 (HSP60) are elevated in chronic periodontitis patients compared with non-diseased subjects. The aim...
Pathogenetic roles of Synoviolin in synovial hyperplasia of rheumatoid arthritis (2003)
Yamasaki, S, Yagishita, N, Amano, T, Tsuchimochi, K, Maruyama, I, Nishioka, K, ...
No abstract available.
Tsuchimochi, K, Yamasaki, S, Yagishita, N, Amano, T, Komiya, S, Maruyama, I, ...
No abstract available.
The importance of Synoviolin in embryogenesis (2003)
Yagishita, N, Amano, T, Yamasaki, S, Tsuchimochi, T, Nishioka, K, Maruyama, I, ...
No abstract available.
Synoviolin as a novel pathogenic factor for arthropathy (2003)
Amano, T, Yamasaki, S, Yagishita, N, Tsuchimochi, K, Fukamizu, A, Maruyama, I, ...
No abstract available.
The discovery of novel structural and physical properties in the $A$-site ordered manganite $R$BaMn$_2$O$_6$ ($R$ = Y and rare earth elements) has demanded new comprehension about perovskite...
An Optical and Near Infrared Search for Brown Dwarfs in the Pleiades Cluster (2003)
Nagashima, C., Dobbie, P. D., Nagayama, T., Nakajima, Y., Nagata, T., Tamura, M., ...
We have carried out a brown dwarf search over an area of 14' x 23' near the central portion of the Pleiades open cluster in five optical and near infrared bands (i', Z, J, H, Ks) with 10 sigma...
Relativistic and correlated calculations on the ground and excited states of ThO. (2003)
Paulovic, J., Nakajima, T., Hirao, K., Lindh, R., Malmqvist, P.-Å.
We report on the performance of the third-order Douglas–Kroll ab initio model potential (DK3-AIMP) method-based electron-correlated spin–orbit calculations. Our treatment assumes that the problem...
Yamazaki, K, Ueki-Maruyama, K, Oda, T, Tabeta, K, Shimada, Y, Tai, H, ...
It has been reported that there is a relationship between a single-nucleotide polymorphism (SNP) in the promoter region of the CD 14 gene at position -159 (C-->T) and infectious diseases. The aim...
New Stacking Variations of the CE-type Structure in the Metal-Ordered Manganite YBaMn2O6 (2002)
Kageyama, H., Nakajima, T., Ichihara, M., Ueda, Y., Yoshizawa, H., Ohoyama, K.
For the paramagnetic insulating phase in the metal-ordered manganite YBaMn2O6, the so-called CE-type of charge/orbital ordered state was observed within the monoclinic ab-plane, which is most...
Nakajima, T., Kageyama, H., Yoshizawa, H., Ueda, Y.
New metal-ordered manganites RBaMn_{2}O_{6} have been synthesized and investigated in the structures and electromagnetic properties. RBaMn_{2}O_{6} can be classified into three groups from the...
Hayashi,T., Terrones,M., Scheu,C., Kim,Y. A., Rühle,M., Nakajima,T., ...
A comparison of model- and satellite-derived aerosol optical depth and reflectivity (2002)
Penner,J. E., Zhang,S. Y., Chin,M., Chuang,C. C., Feichter,Johann, Feng,Y., ...
The determination of an accurate quantitative understanding of the role of tropospheric aerosols in the earth's radiation budget is extremely important because forcing by anthropogenic aerosols...
A comparison of model- and satellite-derived aerosol optical depth and reflectivity (2002)
Penner, J. E., Zhang, S. Y., Chin, M., Chuang, C. C., Feichter, Johann, Feng, Y., ...
The determination of an accurate quantitative understanding of the role of tropospheric aerosols in the earth's radiation budget is extremely important because forcing by anthropogenic aerosols...
A comparison of model- and satellite-derived aerosol optical depth and reflectivity (2002)
Penner, J. E., Zhang, S., Chin, M., Chuang, C. C., Feichter, J., Feng, Y., ...
Hosotani, Y., Nakajima, T., Daghigh, R. G., Kapusta, J. I.
When a potential for a scalar field has two local minima there arise spherical shell-type solutions of the classical field equations due to gravitational attraction. We establish such solutions...
Successive Phase Transitions in a Metal-Ordered Manganite Perovskite YBaMn2O6 (2001)
Nakajima, T., Kageyama, H., Ueda, Y.
Structural, magnetic and electric properties of a metal-ordered perovskite YBaMn2O6 have been studied by means of powder X-ray diffraction, DSC, magnetic susceptibility, and electric resistivity. It...
Coronagraphic Survey for Companions of Stars within 8 pc (2001)
Oppenheimer, B. R., Golimowski, D. A., Kulkarni, S. R., Matthews, K., Nakajima, T., Creech-Eakman, M., ...
We present the technique and results of a survey of stars within 8 pc of the Sun with declinations $\bf\delta > -35\arcdeg$ (J2000.00). The survey, designed to find without color bias faint...
Yamashita, H, Nishimura, M, Bessho, H, Takada, S, Nakajima, T, Hada, M, ...
Analysis of polyphenols in green tea using a polyphenol sensor (2001)
Horie, H, Ujihara, T, Kohata, K, Uematsu, H, Nakajima, T, Hiromato, M, ...
Infrared Star Count Models and Their Application to the Subaru Deep Field (2000)
Nakajima, T., Iwamuro, F., Maihara, T., Motohara, K., Terada, H., Goto, M., ...
We construct infrared star count models of the Galaxy applicable at faint magnitudes. In addition to dwarfs and subdwarfs, we also take into account L dwarfs, T dwarfs, and white dwarfs of both disk...
Yamazaki, K., Nakajima, T., Ohsawa, Y., Tabeta, K., Yoshie, H., Sakurai, K., ...
Chronic inflammatory periodontal diseases are characterized by a cellular infiltrate and are similar in many respects to other chronic inflammatory diseases. While periodontopathic bacteria have been...
Yamazaki, K., Nakajima, T., Ohsawa, Y., Tabeta, K., Yoshie, H., Sakurai, K., ...
Chronic inflammatory periodontal diseases are characterized by a cellular infiltrate and are similar in many respects to other chronic inflammatory diseases. While periodontopathic bacteria have been...
Radiative Forcing by Contrails (1999)
Meerkötter, R., Schumann, U., Dölling, D.R., Minnis, P., Nakajima, T., Tsushima, Y.
A parametric study of the instantaneous radiative impact of contrails is presented using three different radiative transfer models for a series of model atmospheres and cloud parameters. Contrails...
Aviation-Produced Aerosols and Cloudiness (1999)
Fahey, D.W., Schumann, U., Ackerman, S., Artaxo, P., Boucher, O., Danilin, M.Y., ...
Clonal accumulation of T cells in gingival lesion of periodontitis patients (1999)
Yamazaki, K., Sakurai, K., Nakajima, T., Seymour, G. J., Hara, K.
T cell antigen specificity in humans following stimulation with Porphyromonas gingivalis (1999)
Nakajima, T., Yamazaki, K., Cullinan, M. P., Gemmell, E., Seymour, G. J.
Radiative forcing by contrails (1999)
Meerkötter, R., Schumann, U., Doelling, D. R., Minnis, P., Nakajima, T., Tsushima, Y.
A parametric study of the instantaneous radiative impact of contrails is presented using three different radiative transfer models for a series of model atmospheres and cloud parameters. Contrails...
Radiative forcing by contrails (1999)
Meerkötter, R., Schumann, U., Doelling, D. R., Minnis, P., Nakajima, T., Tsushima, Y.
A parametric study of the instantaneous radiative impact of contrails is presented using three different radiative transfer models for a series of model atmospheres and cloud parameters. Contrails...
Clonal accumulation of T cells in gingival lesion of periodontitis patients (1999)
Yamazaki, K., Sakurai, K., Nakajima, T., Seymour, G. J., Hara, K.
T cell antigen specificity in humans following stimulation with Porphyromonas gingivalis (1999)
Nakajima, T., Yamazaki, K., Cullinan, M. P., Gemmell, E., Seymour, G. J.
Igic,R., Nakajima,T., Yeh,H. S. J., Sorrells,K., Erdos,E. G.
Bradykinin is inactivated when any one of its eight peptide bonds is cleaved. The term kininase was coined when the structure of kinins was still unknown, although enzymes should obviously not be...
The Plasma Kallikrein-Kinin System in Non-Mammalian Blood: Evolutionary Aspects. (1998)
Erdoes,Ervin G., Seki,T., Miwa,I., Nakajima,T.
Presented are studies on four components of the plasma kallikrein-kinin system in blood of vertebrates ranging from mammalian to piscine: (1) prekallikrein activator (factor XII or Hageman factor);...
Purification of the Angiotensin I Converting Enzyme of the Lung. (1998)
Nakajima,T., Oshima,G., Yeh,H. S. J., Igic,R., Erdoes,E. G.
The angiotensin I converting enzyme (peptidyl dipeptide hydrolase) was purified from hog lung. The molecular weight of the enzyme in SDS polyacrylamide gel electrophoresis was established as 206,000....
Nakajima, T., Koyama, A., Kuraoka, Y., Matsumoto, K., Yoshizawa, M.
The carbon-fiber-reinforced plastic (CFRP) that can be used for window material in place of beryllium is a composite-type material comprising twisted carbon fibers and bisphenol-A plastic. Since the...
KamLAND: a liquid scintillator anti-neutrino detector at the Kamioka site (1998)
Alivisatos, P, Berridge, S C, Bokor, N, Britton, C L, Bryan, W, Bugg, W M, ...
Tanaka, Masatoshi, Fujisawa, Y., Nakajima, T., Tasaka, Y., Ota, K., Usami, S., ...
Laser ablation of NiO at 266 nm has been studied by measuring absorption spectra and emission spectra which are resolved both temporally and spatially. The spectra were measured at several points 1...
Spin-squeezed Ground States in the Bilayer Quantum Hall Ferromagnet (1997)
A "squeezed-vacuum" state considered in quantum optics is shown to be realized in the ground-state wavefunction for the bilayer quantum Hall system at the total Landau level filling of $\nu=1/m$ (m:...
Spindle cell carcinoma of the breast (1997)
Maemura, M, Iino, Y, Oyama, T, Hikino, T, Yokoe, T, Takei, H, ...
Atrial conduction abnormalities in patients with systemic progressive sclerosis (1997)
Mizuno, R., Fujimoto, S., Nakano, H., Nakajima, T., Kimura, A., Nakagawa, Y., ...
Background Atrial abnormalities in patients with progressive systemic sclerosis have not been evaluated in terms of intra-artrial conduction. We hypothesized that a delay in atrial conduction in...
Modelling of radiation quantities and photolysis frequencies in the troposphere. (1996)
Ruggaber, A., Dlugi, R., Forkel, R., Seidl, W., Hass, H., Nakajima, T., ...
Ebel, A. [Hrsg.]
Composite-Fermion Analysis of the Double-Layer Fractional Quantum Hall System (1995)
Effect of interlayer tunneling in the double-layer fractional quantum Hall system at the total Landau level filling of $\nu=1/m$ ($m$: odd integer) is analyzed with the composite-fermion approach in...
Tumour necrosis factor-α in nasal allergy (1995)
K. Hisamatsu, T. Ganbo, T. Nakazawa, T. Nakajima, J. Ko, R. Goto, ...
Tumour necrosis factor-α (TNF-α) was measured by enzyme-linked immunosorbent assay and eosinophil cationic protein (ECP) by radio-immunoassay to evaluate TNF-α in nasal allergy. There was no...
Pneumocystis carinii pneumonia during treatment for recurrent breast cancer: a case report (1995)
Koibuchi, Y, Iino, Y, Yokoe, T, Oyama, T, Nakajima, T, Morishita, Y
Pulmonary epithelioid hemangioendothelioma: a case report (1995)
Kawashima, O, Yoshida, I, Ohtani, Y, Ishikawa, S, Ohtaki, A, Maeshima, A, ...
Manifestation of spin degrees of freedom in the double fractional quantum Hall system (1994)
The double fractional quantum Hall system of spin 1/2 electrons is numerically studied to predict that there exists a novel spin-unpolarized quantum liquid specific to the multi-species system, which...
Composite-Fermion Picture for the Spin-Wave Excitation in the fractional quantum Hall system (1994)
Spin-wave excitation mode from the spin-polarized ground state in the fractional quantum Hall liquid with odd fractions ($\nu=1/3,1/5$) numerically obtained by the exact diagonalization of finite...
The Effect of Lyso-PAF on Ciliary Activity of Human Paranasal Sinus Mucosa in vitro (1994)
T. Ganbo, K. Hisamatsu, H. Inoue, T. Nakajima, Y. Murakami
The effect of lyso-PAF on ciliated cells was investigated in vitro. Normal mucosa was surgically obtained from human paranasal sinuses and incubated in the form of tissue culture. Ciliated epithelium...
Frequency Distribution of Quasi-Effective Energy of Natural Radiation in Japan (1991)
Nakajima, T., Otsuki, T., Nenoi, M., Koshijima, T.
The quasi-effective energy of natural radiation, excluding the hard component of cosmic radiation, was evaluated at 768 sites in Japan using (a) an equation of relationship between the...
The quasi-exposure rate and the quasi-effective energy of the natural radiation in the field at 47 monitoring points in Japan have been studied with the pair-filter thermoluminescence dosemeter...
The quasi-exposure rate and the quasi-effective energy of the natural radiation in the field at 47 monitoring points in Japan have been measured with the pair filter thermoluminescence dosemeter...
Thermoluminescence of Quartz in a Wrist Watch: Possibility for Use as an Emergency Dosemeter (1988)
Investigation of the TL properties of the quartz oscillator elements used in wrist watches has revealed that the sensitivity of such quartz elements is too small for the watches to be used as...
Chakrabarti, S., Sima, Anders A. F., Nakajima, T., Yagihashi, S., Greene, D. A.
Aldose reductase was purified from testis of nondiabetic BB rats using DEAE cellulose, hydroxylapatite and sephadex G-100 column chromatography. The molecular weight of the isolated enzyme was found...
STARK SHIFT AND BROADENING OF ATOMIC LINES AS OBSERVED ON OPTOGALVANIC SPECTRA OF NOBLE GASES (1983)
Nakajima, T., Uchitomi, N., Adachi, Y., Maeda, S., Hirose, C.
We report on the Stark effect, caused by the electric field present inside the cathode-fall region, of atomic lines of noble gases as observed by optogalvanic spectroscopy of hollow cathode discharge.
Field Trial of Composite Fiber-Optic Overhead Ground Wire, (1983)
Kubota,S., Kawahira,H., Nakajima,T., Matsubara,I., Saito,Y.
A composite fiber-optic ground wire (OPGW), which provides additional communication capabilities for system protection and control of overhead power transmission systems has been developed. After...
STARK SHIFT AND BROADENING OF ATOMIC LINES AS OBSERVED ON OPTOGALVANIC SPECTRA OF NOBLE GASES (1983)
Nakajima, T., Uchitomi, N., Adachi, Y., Maeda, S., Hirose, C.
We report on the Stark effect, caused by the electric field present inside the cathode-fall region, of atomic lines of noble gases as observed by optogalvanic spectroscopy of hollow cathode discharge.
STARK SHIFT AND BROADENING OF ATOMIC LINES AS OBSERVED ON OPTOGALVANIC SPECTRA OF NOBLE GASES (1983)
Nakajima, T., Uchitomi, N., Adachi, Y., Maeda, S., Hirose, C.
We report on the Stark effect, caused by the electric field present inside the cathode-fall region, of atomic lines of noble gases as observed by optogalvanic spectroscopy of hollow cathode discharge.
The beta energy absorbed in the thermoluminescent (TL) phosphor was determined directly from the difference in the pulse height spectrum between incident and transmitted beta particles to and from...
TL Dating of Fish Fossil from Brazil (1983)
Matsuoka, M., Takatohi, U.E., Watanabe, S., Nakajima, T.
The determination of the geological age of a fish fossil found in northeastern Brasil was investigated using a thermoluminescence method. The natural accumulated radiation dose was determined from...
The Effect of Pulverisation of Irradiated Materials on Their Thermoluminescence Emission (1983)
The effect of pulverisation on the thermoluminescence (TL) emission from irradiated substances was studied to obtain a more accurate value for the dose received by the irradiated substances. When...
OBSERVATIONAL STUDY ON THE RADIATIVE PROPERTIES OF ATMOSPHERIC AEROSOLS OVER CHINA
高村, 民雄, Takamura, T., Xu, L., Wang, B., Jin, X., ...
OBSERVATIONAL STUDY ON THE RADIATIVE PROPERTIES OF ATMOSPHERIC AEROSOLS OVER CHINA
高村, 民雄, Takamura, T., Xu, L., Wang, B., Jin, X., ...
Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP.
Brindle, P, Nakajima, T, Montminy, M
The second messenger cAMP stimulates the expression of numerous genes via the protein kinase A-mediated phosphorylation of the cAMP response element-binding protein (CREB) at Ser-133. Ser-133...
Matsumura, H, Nakajima, T, Osaka, T, Satoh, S, Kawase, K, Kubo, E, ...
The site of action for the sleep-promoting effect of prostaglandin (PG) D2 was extensively examined in the brain of adult male rats (n = 231). PGD2 was administered at 100 pmol/0.2 microliter per min...
Nakajima, T, Kinoshita, S, Sasagawa, T, Sasaki, K, Naruto, M, Kishimoto, T, ...
NF-IL6, a member of the basic leucine zipper (bZIP) family transcription factors, is involved in expression of inducible genes involved in immune and inflammatory responses. We observed that...
In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent.
Tanio, T, Ichise, K, Nakajima, T, Okuda, T
SM-8668 (Sch 39304) is a new oral antifungal agent which we evaluated in comparison with fluconazole in various fungal infection models. The prophylactic effect of SM-8668 was excellent against...
Yabe, T, Yamada-Okabe, T, Kasahara, S, Furuichi, Y, Nakajima, T, Ichishima, E, ...
We previously isolated the Saccharomyces cerevisiae HKR1 gene that confers on S. cerevisiae cells resistance to HM-1 killer toxin secreted by Hansenula mrakii (S. Kasahara, H. Yamada, T. Mio, Y....
Role of three chitin synthase genes in the growth of Candida albicans.
Mio, T, Yabe, T, Sudoh, M, Satoh, Y, Nakajima, T, Arisawa, M, ...
The CHS2 and CHS3 genes of Candida albicans were disrupted. The double disruptant was still viable. Assessment of chitin and of calcofluor white resistance shows that CHS1 is responsible for septum...
Mio, T, Yamada-Okabe, T, Yabe, T, Nakajima, T, Arisawa, M, Yamada-Okabe, H
Cell wall beta-glucan in a pathogenic fungus, Candida albicans, is highly branched with beta-1,3 and beta-1,6 linkages. We have isolated the C. albicans cDNAs for KRE6 and SKN1, the genes required...
Uchiyama, H, Nakajima, T, Yagi, O, Nakahara, T
Biodegradation experiments with radioactively labeled trichloroethylene showed that 32% of the radioactive carbon was converted to glyoxylic acid, dichloroacetic acid and trichloroacetic acid and...
Continuous-sterilization system that uses photosemiconductor powders.
Matsunaga, T, Tomoda, R, Nakajima, T, Nakamura, N, Komine, T
We report a novel photochemical sterilization system in which Escherichia coli cells were sterilized with photosemiconductor powders (titanium oxide). For sterilization that could be used in...
Kasahara, S, Yamada, H, Mio, T, Shiratori, Y, Miyamoto, C, Yabe, T, ...
A gene whose overexpression can endow Saccharomyces cerevisiae cells with resistance to HM-1 killer toxin was cloned from an S. cerevisiae genomic library. This gene, designated HKR1 (Hansenula...
The G1/S boundary-specific enhancer of the rat cdc2 promoter.
Shimizu, M, Ichikawa, E, Inoue, U, Nakamura, T, Nakajima, T, Nojima, H, ...
Multiple species of G1 cyclins and cyclin-dependent kinases are induced sequentially during G1 phase, and the expression of cyclin A and cdc2 genes is subsequently induced at the G1/S boundary. To...
Suzuki, M, Kuroda, C, Oda, E, Tsunoda, S, Nakamura, T, Nakajima, T, ...
Downregulation of the fibronectin (FN) gene in a rat 3Y1 derivative cell line, XhoC, transformed by the adenovirus E1A and E1B genes seems to be caused by the induction of a negative regulator,...
Parker, D, Ferreri, K, Nakajima, T, LaMorte, V J, Evans, R, Koerber, S C, ...
We have characterized a phosphoserine binding domain in the coactivator CREB-binding protein (CBP) which interacts with the protein kinase A-phosphorylated, and hence activated, form of the cyclic...
Electrochemical classification of gram-negative and gram-positive bacteria.
Intestinal bacteria were classified as gram-positive or gram-negative by an electrode system with a basal plane pyrolytic graphite electrode and a porous nitrocellulose membrane filter to trap...
Nakamura, T, Nakajima, T, Tsunoda, S, Nakada, S, Oda, K, Tsurui, H, ...
The level of fibronectin (FN) gene expression is very high in resting rat 3Y1 cells but greatly decreased in adenovirus E1-transformed cells. To study the mechanism of this down-regulation, nuclear...
Overgrowth of human synovial cells driven by the human T cell leukemia virus type I tax gene.
Nakajima, T, Aono, H, Hasunuma, T, Yamamoto, K, Maruyama, I, Nosaka, T, ...
One of the salient pathological features of rheumatoid arthritis is synovial cell proliferation with bone erosion. Despite extensive investigation, the factors essential for synovial cell...
Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines.
Shichiri, M, Hirata, Y, Nakajima, T, Ando, K, Imai, T, Yanagisawa, M, ...
We studied whether a novel vasoconstrictor peptide, endothelin-1 (ET-1), is synthesized by and released from human carcinoma cell lines, and whether ET-1 stimulates proliferation of these tumor...
Kitajima, I, Yamamoto, K, Sato, K, Nakajima, Y, Nakajima, T, Maruyama, I, ...
To investigate the pathogenesis of human T cell lymphotropic virus type I (HTLV-I)-associated chronic inflammatory arthropathy (HAAP), we sought to detect proviral DNA in the articular lesions. For...
Matsuo, M, Masumura, T, Nishio, H, Nakajima, T, Kitoh, Y, Takumi, T, ...
Recent molecular studies have shown that in a patient with Duchenne muscular dystrophy (DMD) Kobe, the size of exon 19 of the dystrophin gene was reduced to 36 bp due to the deletion of 52 bp out of...
Liberation of serotonin from rabbit blood platelets by bacterial cell walls and related compounds.
Harada, K, Kotani, S, Takada, H, Tsujimoto, M, Hirachi, Y, Kusumoto, S, ...
A study was made on the activity of various bacterial cell walls and peptidoglycans to liberate serotonin from rabbit blood platelets. All of the test cell walls or peptidoglycans prepared from 27...
Isshiki, H, Akira, S, Tanabe, O, Nakajima, T, Shimamoto, T, Hirano, T, ...
The interleukin-6 (IL-6) promoter is rapidly and transiently activated with other cytokines, including IL-1, tumor necrosis factor, and platelet-derived growth factor, as well as phorbol esters and...
E1A-responsive elements for repression of rat fibronectin gene transcription.
Nakajima, T, Nakamura, T, Tsunoda, S, Nakada, S, Oda, K
The level of fibronectin (FN) gene transcription in resting rat 3Y1 cells is very high but decreases steeply after growth stimulation by serum or by the induction of E1A expression. To study the...
Nakajima, T, Masuda-Murata, M, Hara, E, Oda, K
Rat 3Y1 cell lines that express either adenovirus type 12 E1A 13S mRNA or 12S mRNA in response to dexamethasone treatment were established by introduction of recombinant vector DNA containing the E1A...
Shimada, A, Kimura, S, Abe, K, Nagasaki, K, Adachi, I, Yamaguchi, K, ...
Estrogen receptor (ER) in human breast cancer tissues was demonstrated in paraffin sections as well as in frozen sections by immunoperoxidase methods using monoclonal antibody (H222) against ER. The...
Yeast manno-protein biosynthesis: solubilization and selective assay of four mannosyltransferases.
Using appropriate yeast strains and exogenous acceptors, we have devised specific assays for four mannosyltransferase activities involved in biosynthesis of the carbohydrate outer chain of yeast...
Colorectal tumours and pit pattern.
Kudo, S, Hirota, S, Nakajima, T, Hosobe, S, Kusaka, H, Kobayashi, T, ...
AIMS--To investigate the morphological and histopathological associations between an individual pit seen on stereomicroscopy or magnifying colonoscopy and an individual crypt seen in histological...
Inoue, I, Nakajima, T, Williams, C S, Quackenbush, J, Puryear, R, Powers, M, ...
In earlier studies, we provided statistical evidence that individual differences in the angiotensinogen gene, the precursor of the vasoactive hormone angiotensin II, constitute inherited...
The calmodulin-binding domain in the mouse type 1 inositol 1,4,5-trisphosphate receptor.
Yamada, M, Miyawaki, A, Saito, K, Nakajima, T, Yamamoto-Hino, M, Ryo, Y, ...
We determined the amino acid sequence responsible for the calmodulin (CaM)-binding ability of mouse type 1 Ins(1,4,5)P3 receptor (IP3R1). We expressed various parts of IP3R1 from deleted cDNA and...
Yasuda, T, Takeshita, H, Nakajima, T, Hosomi, O, Nakashima, Y, Kishi, K
DNase I from rabbit urine was purified approx. 3600-fold to apparent homogeneity with a 41% yield by affinity chromatography utilizing DNA-cellulose; the purity of the final preparation was assessed...
Lebrun, B, Romi-Lebrun, R, Martin-Eauclaire, M F, Yasuda, A, Ishiguro, M, Oyama, Y, ...
A new toxin, named HsTX1, has been identified in the venom of Heterometrus spinnifer (Scorpionidae), on the basis of its ability to block the rat Kv1.3 channels expressed in Xenopus oocytes. HsTX1...
Ichishima, E, Taya, N, Ikeguchi, M, Chiba, Y, Nakamura, M, Kawabata, C, ...
For the construction of an overexpression system of the intracellular 1,2-alpha-mannosidase (EC 3.2.1.113) gene (msdS) from Aspergillus saitoi (now designated Aspergillus phoenicis), the N-terminal...
Identification of copper ligands in Aspergillus oryzae tyrosinase by site-directed mutagenesis.
Nakamura, M, Nakajima, T, Ohba, Y, Yamauchi, S, Lee, B R, Ichishima, E
Copper ligands of the recombinant tyrosinase from the fungus Aspergillus oryzae expressed in Saccharomyces cerevisiae or Escherichia coli were identified by site-directed mutagenesis. The recombinant...
Takeshita, H, Yasuda, T, Iida, R, Nakajima, T, Mori, S, Mogi, K, ...
We purified four amphibian deoxyribonucleases I from the pancreases of one toad, two frog and one newt species, by using three different column chromatography methods in sequence. Each of the...
Corzo, G, Escoubas, P, Villegas, E, Barnham, K J, He, W, Norton, R S, ...
Two novel antimicrobial peptides have been identified and characterized from venom of the African scorpion Pandinus imperator. The peptides, designated pandinin 1 and 2, are alpha-helical...
Haplotype and mutation analysis in Japanese patients with Wilson disease.
Nanji, M S, Nguyen, V T, Kawasoe, J H, Inui, K, Endo, F, Nakajima, T, ...
Wilson disease (WD), an autosomal recessive disorder of copper transport, is characterized by impaired biliary excretion and by impaired incorporation of copper into ceruloplasmin. Toxic accumulation...
A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.
Akira, S, Isshiki, H, Sugita, T, Tanabe, O, Kinoshita, S, Nishio, Y, ...
NF-IL6 is a nuclear factor that specifically binds to an IL1-responsive element in the IL-6 gene. In this study the gene encoding NF-IL6 has been cloned by direct screening of a lambda gt11 library...
Hazama, H, Nakajima, T, Hamada, E, Omata, M, Kurachi, Y
1. Membrane currents were recorded by a patch clamp technique in guinea-pig tracheal myocytes, using the whole cell mode with Cs(+) internal solution. 2. Both neurokinin A (NKA, 1 mu M) and caffeine...
Iwasawa, K, Nakajima, T, Hazama, H, Goto, A, Shin, W S, Toyo-oka, T, ...
1. The effects of extracellular pH (pHo) on receptor (vasopressin or endothelin-1)-mediated Ca2- entry and Ca(2+)-permeable channels were investigated in aortic smooth muscle cells (A7r5) from rat...
Regulation of spontaneous opening of muscarinic K+ channels in rabbit atrium.
Kaibara, M, Nakajima, T, Irisawa, H, Giles, W
1. Intracellular mechanism(s) for controlling the opening of muscarinic K+ channels in the absence of an applied muscarinic agonist were studied in rabbit atrium by applying the patch clamp technique...
Modulation of the delayed rectifier K+ current by isoprenaline in bull-frog atrial myocytes.
Giles, W, Nakajima, T, Ono, K, Shibata, E F
1. The effects of isoprenaline (ISO) on the calcium current (ICa) and delayed rectifier K+ current (IK) were examined using a tight-seal whole-cell voltage-clamp technique in single cells from...
Two distinct types of inwardly rectifying K+ channels in bull-frog atrial myocytes.
Clark, R B, Nakajima, T, Giles, W, Kanai, K, Momose, Y, Szabo, G
1. Single atrial myocytes were enzymatically isolated from the bull-frog as previously described (Hume & Giles, 1981), and patch-clamp techniques were used in an attempt to identify and separate two...
Kosaka, H, Uozumi, M, Nakajima, T
Nitrogen dioxide induced SOS functions in Salmonella typhimurium and Escherichia coli K-12 and was mutagenic in Escherichia coli WP2. When a rabbit was administered aminopyrine intravenously and...
Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP.
Brindle, P, Nakajima, T, Montminy, M
The second messenger cAMP stimulates the expression of numerous genes via the protein kinase A-mediated phosphorylation of the cAMP response element-binding protein (CREB) at Ser-133. Ser-133...
Matsumura, H, Nakajima, T, Osaka, T, Satoh, S, Kawase, K, Kubo, E, ...
The site of action for the sleep-promoting effect of prostaglandin (PG) D2 was extensively examined in the brain of adult male rats (n = 231). PGD2 was administered at 100 pmol/0.2 microliter per min...
Nakajima, T, Kinoshita, S, Sasagawa, T, Sasaki, K, Naruto, M, Kishimoto, T, ...
NF-IL6, a member of the basic leucine zipper (bZIP) family transcription factors, is involved in expression of inducible genes involved in immune and inflammatory responses. We observed that...
In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent.
Tanio, T, Ichise, K, Nakajima, T, Okuda, T
SM-8668 (Sch 39304) is a new oral antifungal agent which we evaluated in comparison with fluconazole in various fungal infection models. The prophylactic effect of SM-8668 was excellent against...
Yabe, T, Yamada-Okabe, T, Kasahara, S, Furuichi, Y, Nakajima, T, Ichishima, E, ...
We previously isolated the Saccharomyces cerevisiae HKR1 gene that confers on S. cerevisiae cells resistance to HM-1 killer toxin secreted by Hansenula mrakii (S. Kasahara, H. Yamada, T. Mio, Y....
Role of three chitin synthase genes in the growth of Candida albicans.
Mio, T, Yabe, T, Sudoh, M, Satoh, Y, Nakajima, T, Arisawa, M, ...
The CHS2 and CHS3 genes of Candida albicans were disrupted. The double disruptant was still viable. Assessment of chitin and of calcofluor white resistance shows that CHS1 is responsible for septum...
Mio, T, Yamada-Okabe, T, Yabe, T, Nakajima, T, Arisawa, M, Yamada-Okabe, H
Cell wall beta-glucan in a pathogenic fungus, Candida albicans, is highly branched with beta-1,3 and beta-1,6 linkages. We have isolated the C. albicans cDNAs for KRE6 and SKN1, the genes required...
Uchiyama, H, Nakajima, T, Yagi, O, Nakahara, T
Biodegradation experiments with radioactively labeled trichloroethylene showed that 32% of the radioactive carbon was converted to glyoxylic acid, dichloroacetic acid and trichloroacetic acid and...
Continuous-sterilization system that uses photosemiconductor powders.
Matsunaga, T, Tomoda, R, Nakajima, T, Nakamura, N, Komine, T
We report a novel photochemical sterilization system in which Escherichia coli cells were sterilized with photosemiconductor powders (titanium oxide). For sterilization that could be used in...
Kasahara, S, Yamada, H, Mio, T, Shiratori, Y, Miyamoto, C, Yabe, T, ...
A gene whose overexpression can endow Saccharomyces cerevisiae cells with resistance to HM-1 killer toxin was cloned from an S. cerevisiae genomic library. This gene, designated HKR1 (Hansenula...
The G1/S boundary-specific enhancer of the rat cdc2 promoter.
Shimizu, M, Ichikawa, E, Inoue, U, Nakamura, T, Nakajima, T, Nojima, H, ...
Multiple species of G1 cyclins and cyclin-dependent kinases are induced sequentially during G1 phase, and the expression of cyclin A and cdc2 genes is subsequently induced at the G1/S boundary. To...
Suzuki, M, Kuroda, C, Oda, E, Tsunoda, S, Nakamura, T, Nakajima, T, ...
Downregulation of the fibronectin (FN) gene in a rat 3Y1 derivative cell line, XhoC, transformed by the adenovirus E1A and E1B genes seems to be caused by the induction of a negative regulator,...
Parker, D, Ferreri, K, Nakajima, T, LaMorte, V J, Evans, R, Koerber, S C, ...
We have characterized a phosphoserine binding domain in the coactivator CREB-binding protein (CBP) which interacts with the protein kinase A-phosphorylated, and hence activated, form of the cyclic...
Electrochemical classification of gram-negative and gram-positive bacteria.
Intestinal bacteria were classified as gram-positive or gram-negative by an electrode system with a basal plane pyrolytic graphite electrode and a porous nitrocellulose membrane filter to trap...
Nakamura, T, Nakajima, T, Tsunoda, S, Nakada, S, Oda, K, Tsurui, H, ...
The level of fibronectin (FN) gene expression is very high in resting rat 3Y1 cells but greatly decreased in adenovirus E1-transformed cells. To study the mechanism of this down-regulation, nuclear...
Overgrowth of human synovial cells driven by the human T cell leukemia virus type I tax gene.
Nakajima, T, Aono, H, Hasunuma, T, Yamamoto, K, Maruyama, I, Nosaka, T, ...
One of the salient pathological features of rheumatoid arthritis is synovial cell proliferation with bone erosion. Despite extensive investigation, the factors essential for synovial cell...
Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines.
Shichiri, M, Hirata, Y, Nakajima, T, Ando, K, Imai, T, Yanagisawa, M, ...
We studied whether a novel vasoconstrictor peptide, endothelin-1 (ET-1), is synthesized by and released from human carcinoma cell lines, and whether ET-1 stimulates proliferation of these tumor...
Kitajima, I, Yamamoto, K, Sato, K, Nakajima, Y, Nakajima, T, Maruyama, I, ...
To investigate the pathogenesis of human T cell lymphotropic virus type I (HTLV-I)-associated chronic inflammatory arthropathy (HAAP), we sought to detect proviral DNA in the articular lesions. For...
Matsuo, M, Masumura, T, Nishio, H, Nakajima, T, Kitoh, Y, Takumi, T, ...
Recent molecular studies have shown that in a patient with Duchenne muscular dystrophy (DMD) Kobe, the size of exon 19 of the dystrophin gene was reduced to 36 bp due to the deletion of 52 bp out of...
Liberation of serotonin from rabbit blood platelets by bacterial cell walls and related compounds.
Harada, K, Kotani, S, Takada, H, Tsujimoto, M, Hirachi, Y, Kusumoto, S, ...
A study was made on the activity of various bacterial cell walls and peptidoglycans to liberate serotonin from rabbit blood platelets. All of the test cell walls or peptidoglycans prepared from 27...
Isshiki, H, Akira, S, Tanabe, O, Nakajima, T, Shimamoto, T, Hirano, T, ...
The interleukin-6 (IL-6) promoter is rapidly and transiently activated with other cytokines, including IL-1, tumor necrosis factor, and platelet-derived growth factor, as well as phorbol esters and...
E1A-responsive elements for repression of rat fibronectin gene transcription.
Nakajima, T, Nakamura, T, Tsunoda, S, Nakada, S, Oda, K
The level of fibronectin (FN) gene transcription in resting rat 3Y1 cells is very high but decreases steeply after growth stimulation by serum or by the induction of E1A expression. To study the...
Nakajima, T, Masuda-Murata, M, Hara, E, Oda, K
Rat 3Y1 cell lines that express either adenovirus type 12 E1A 13S mRNA or 12S mRNA in response to dexamethasone treatment were established by introduction of recombinant vector DNA containing the E1A...
Shimada, A, Kimura, S, Abe, K, Nagasaki, K, Adachi, I, Yamaguchi, K, ...
Estrogen receptor (ER) in human breast cancer tissues was demonstrated in paraffin sections as well as in frozen sections by immunoperoxidase methods using monoclonal antibody (H222) against ER. The...
Yeast manno-protein biosynthesis: solubilization and selective assay of four mannosyltransferases.
Using appropriate yeast strains and exogenous acceptors, we have devised specific assays for four mannosyltransferase activities involved in biosynthesis of the carbohydrate outer chain of yeast...
Colorectal tumours and pit pattern.
Kudo, S, Hirota, S, Nakajima, T, Hosobe, S, Kusaka, H, Kobayashi, T, ...
AIMS--To investigate the morphological and histopathological associations between an individual pit seen on stereomicroscopy or magnifying colonoscopy and an individual crypt seen in histological...
Inoue, I, Nakajima, T, Williams, C S, Quackenbush, J, Puryear, R, Powers, M, ...
In earlier studies, we provided statistical evidence that individual differences in the angiotensinogen gene, the precursor of the vasoactive hormone angiotensin II, constitute inherited...
A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.
Akira, S, Isshiki, H, Sugita, T, Tanabe, O, Kinoshita, S, Nishio, Y, ...
NF-IL6 is a nuclear factor that specifically binds to an IL1-responsive element in the IL-6 gene. In this study the gene encoding NF-IL6 has been cloned by direct screening of a lambda gt11 library...
The calmodulin-binding domain in the mouse type 1 inositol 1,4,5-trisphosphate receptor.
Yamada, M, Miyawaki, A, Saito, K, Nakajima, T, Yamamoto-Hino, M, Ryo, Y, ...
We determined the amino acid sequence responsible for the calmodulin (CaM)-binding ability of mouse type 1 Ins(1,4,5)P3 receptor (IP3R1). We expressed various parts of IP3R1 from deleted cDNA and...
Hazama, H, Nakajima, T, Hamada, E, Omata, M, Kurachi, Y
1. Membrane currents were recorded by a patch clamp technique in guinea-pig tracheal myocytes, using the whole cell mode with Cs(+) internal solution. 2. Both neurokinin A (NKA, 1 mu M) and caffeine...
Iwasawa, K, Nakajima, T, Hazama, H, Goto, A, Shin, W S, Toyo-oka, T, ...
1. The effects of extracellular pH (pHo) on receptor (vasopressin or endothelin-1)-mediated Ca2- entry and Ca(2+)-permeable channels were investigated in aortic smooth muscle cells (A7r5) from rat...
Regulation of spontaneous opening of muscarinic K+ channels in rabbit atrium.
Kaibara, M, Nakajima, T, Irisawa, H, Giles, W
1. Intracellular mechanism(s) for controlling the opening of muscarinic K+ channels in the absence of an applied muscarinic agonist were studied in rabbit atrium by applying the patch clamp technique...
Modulation of the delayed rectifier K+ current by isoprenaline in bull-frog atrial myocytes.
Giles, W, Nakajima, T, Ono, K, Shibata, E F
1. The effects of isoprenaline (ISO) on the calcium current (ICa) and delayed rectifier K+ current (IK) were examined using a tight-seal whole-cell voltage-clamp technique in single cells from...
Two distinct types of inwardly rectifying K+ channels in bull-frog atrial myocytes.
Clark, R B, Nakajima, T, Giles, W, Kanai, K, Momose, Y, Szabo, G
1. Single atrial myocytes were enzymatically isolated from the bull-frog as previously described (Hume & Giles, 1981), and patch-clamp techniques were used in an attempt to identify and separate two...
Yasuda, T, Takeshita, H, Nakajima, T, Hosomi, O, Nakashima, Y, Kishi, K
DNase I from rabbit urine was purified approx. 3600-fold to apparent homogeneity with a 41% yield by affinity chromatography utilizing DNA-cellulose; the purity of the final preparation was assessed...
Lebrun, B, Romi-Lebrun, R, Martin-Eauclaire, M F, Yasuda, A, Ishiguro, M, Oyama, Y, ...
A new toxin, named HsTX1, has been identified in the venom of Heterometrus spinnifer (Scorpionidae), on the basis of its ability to block the rat Kv1.3 channels expressed in Xenopus oocytes. HsTX1...
Ichishima, E, Taya, N, Ikeguchi, M, Chiba, Y, Nakamura, M, Kawabata, C, ...
For the construction of an overexpression system of the intracellular 1,2-alpha-mannosidase (EC 3.2.1.113) gene (msdS) from Aspergillus saitoi (now designated Aspergillus phoenicis), the N-terminal...
Identification of copper ligands in Aspergillus oryzae tyrosinase by site-directed mutagenesis.
Nakamura, M, Nakajima, T, Ohba, Y, Yamauchi, S, Lee, B R, Ichishima, E
Copper ligands of the recombinant tyrosinase from the fungus Aspergillus oryzae expressed in Saccharomyces cerevisiae or Escherichia coli were identified by site-directed mutagenesis. The recombinant...
Takeshita, H, Yasuda, T, Iida, R, Nakajima, T, Mori, S, Mogi, K, ...
We purified four amphibian deoxyribonucleases I from the pancreases of one toad, two frog and one newt species, by using three different column chromatography methods in sequence. Each of the...
Corzo, G, Escoubas, P, Villegas, E, Barnham, K J, He, W, Norton, R S, ...
Two novel antimicrobial peptides have been identified and characterized from venom of the African scorpion Pandinus imperator. The peptides, designated pandinin 1 and 2, are alpha-helical...
Kosaka, H, Uozumi, M, Nakajima, T
Nitrogen dioxide induced SOS functions in Salmonella typhimurium and Escherichia coli K-12 and was mutagenic in Escherichia coli WP2. When a rabbit was administered aminopyrine intravenously and...
Haplotype and mutation analysis in Japanese patients with Wilson disease.
Nanji, M S, Nguyen, V T, Kawasoe, J H, Inui, K, Endo, F, Nakajima, T, ...
Wilson disease (WD), an autosomal recessive disorder of copper transport, is characterized by impaired biliary excretion and by impaired incorporation of copper into ceruloplasmin. Toxic accumulation...
OBSERVATIONAL STUDY ON THE RADIATIVE PROPERTIES OF ATMOSPHERIC AEROSOLS OVER CHINA
高村, 民雄, Takamura, T., Xu, L., Wang, B., Jin, X., ...
Sarfati, M, Nakajima, T, Frost, H, Kilccherr, E, Delespesse, G
IgE-binding factors (IgE-BFs) were purified from the culture supernatant of RPMI-8866 cells, a human lymphoblastoid B-cell line expressing IgE receptors. The material, purified by...
Rector, E, Nakajima, T, Rocha, C, Duncan, D, Lestourgeon, D, Mitchell, R S, ...
BALB/c mice were immunized with human lymphoblastoid cells (RPMI 8866 cells) expressing surface receptors for IgE (Fc epsilon R). Spleen cells from animals displaying high titres of anti-Fc epsilon R...
Analysis of electrophoretic mobility histogram of mouse thymocytes during tumour development.
Iwaguchi, T, Shimizu, M, Mori, T, Nakajima, T
The population of medullary thymocytes without peanut agglutinin (PNA) receptor consisted of two groups: Lyt-1+ .2- cells with a high mobility of 1.0 micrometer/sec/V/cm, and Lyt-1+ .2+ cells with a...
Shin, H., Kitajima, I., Nakajima, T., Shao, Q., Tokioka, T., Takasaki, I., ...
OBJECTIVE—To clarify the mechanism of thrombin receptor mediated signal transduction and the induction of cytokines by thrombin stimulation in rheumatoid synovial fibroblasts. METHODS—Cytokines...
Ukaji, F., Kitajima, I., Kubo, T., Shimizu, C., Nakajima, T., Maruyama, I.
OBJECTIVE—To identify rheumatoid arthritis (RA) specific autoantibody and its antigen in the human osteoblast-like cell line, MG-63. METHODS—MG-63 cell extract was subjected to western blotting...
Asamura, H., Nakajima, T., Mukai, K., Noguchi, M., Shimosato, Y.
For determination of the degree of malignancy among thymic epithelial tumors, the DNA content and area of nuclei in 13 cases each of noninvasive thymoma, invasive thymoma, and thymic carcinoma were...
Regression of fundic gland polyps following acquisition of Helicobacter pylori
Watanabe, N, Seno, H, Nakajima, T, Yazumi, S, Miyamoto, S, Matsumoto, S, ...
The prevalence of Helicobacter pylori infection is very low in patients with fundic gland polyps (FGPs) of the stomach. We report here two cases with multiple FGPs that regressed following new H...
Yamazaki, K, Nakajima, T, Hara, K
IL-2, interferon-gamma (IFN-gamma), IL-4 and IL-6 producing T cells in periodontitis and gingivitis-affected human tissues were investigated by immunohistochemistry to clarify the relationship...
Effects of activin A on IgE synthesis and cytokine production by human peripheral mononuclear cells.
Yamashita, N, Nakajima, T, Takahashi, H, Kaneoka, H, Mizushima, Y, Sakane, T
Activin A not only stimulates the synthesis and release of pituitary follicle-stimulating hormone, but exerts various effects on haematopoietic cells, embryos, and fibroblasts. In the present study...
Effect of periodontal treatment on the serum antibody levels to heat shock proteins
YAMAZAKI, K, UEKI-MARUAYAMA, K, HONDA, T, NAKAJIMA, T, SEYMOUR, G J
We have shown previously that both humoral and cellular immune responses to heat shock protein 60 (HSP60) are elevated in chronic periodontitis patients compared with non-diseased subjects. The aim...
SHINTANI, N, NAKAJIMA, T, NAKAKUBO, H, NAGAI, H, KAGITANI, Y, TAKIZAWA, H, ...
We investigated the therapeutic effect and immunological action mechanism of IgG in experimental colitis induced by 3% dextran sulfate sodium in rats. Intravenous injection of homologous (rat) IgG...
KANEKO, S, SUZUKI, N, YAMASHITA, N, NAGAFUCHI, H, NAKAJIMA, T, WAKISAKA, S, ...
BD is prevalent in the area of the Silk Route. It has been shown that hsp are involved in the T cell activation in patients with BD in the UK, where this disease has developed sporadically. We have...
Aoyagi, T, Yamazaki, K, Kabasawa-Katoh, Y, Nakajima, T, Yamashita, N, Yoshie, H, ...
To characterize the T cell response to Porphyromonas gingivalis, we examined the expression of costimulatory molecules on T cells derived from adult periodontitis patients with high serum antibody...
Yamazaki, K, Nakajima, T, Ohsawa, Y, Tabeta, K, Yoshie, H, Sakurai, K, ...
Chronic inflammatory periodontal diseases are characterized by a cellular infiltrate and are similar in many respects to other chronic inflammatory diseases. While periodontopathic bacteria have been...
Nakajima, T., Nomoto, K., Ohfune, Y., Shiratori, Y., Takemoto, T., Takeuchi, H., ...
The effects of the seven glutamic acid analogues, alpha-kainic acid, alpha-allo-kainic acid, domoic acid, erythro-L-tricholomic acid, DL-ibotenic acid, L-quisqualic acid and...
Azuma, H., Ishikawa, M., Nakajima, T., Satoh, A., Sekizaki, S.
The purpose of the present experiments was to investigate the pharmacological mechanisms of the vasoconstriction caused by the toxin (pCrTX) which had been partially purified from the tentacles of...
Savarin, P., Romi-Lebrun, R., Zinn-Justin, S., Lebrun, B., Nakajima, T., Gilquin, B., ...
We have determined the three-dimensional structure of the potassium channel inhibitor HsTX1, using nuclear magnetic resonance and molecular modeling. This protein belongs to the scorpion short toxin...
Biased expression of T cell receptor Vβ genes in periodontitis patients
YAMAZAKI, K, NAKAJIMA, T, GEMMELL, E, KJELDSEN, M, SEYMOUR, G J, HARA, K
The aim of the present study was to investigate the hypothesis that there is selective activation and expansion of a limited repertoire of T cell receptor (TCR)-bearing T cells in periodontitis...
Cortical deafness in multiple sclerosis
Tabira, T, Tsuji, S, Nagashima, T, Nakajima, T, Kuroiwa, Y
Cortical deafness in a patient with multiple sclerosis is reported. Complete recovery from total deafness was seen following stages of auditory agnosia and pure word deafness. The otological and...
Sato, A, Nakajima, T, Fujiwara, Y
A gas chromatographic determination of benzene and toluene in blood with a small amount of blood sample, 0.02 or 0.1 ml, is described. In the method an aliquot of the blood sample in a sealed...
Sato, A, Nakajima, T, Fujiwara, Y, Murayama, N
The sex difference in the susceptibility to haematopoietic disorders induced by benzene was studied kinetically with a special reference to its relation with the body fat content. In rats of both...
Sato, A, Nakajima, T, Fujiwara, Y, Murayama, N
For a better understanding of absorption, distribution, excretion, and metabolism of trichloroethylene the time-course of blood concentration of the vapour and urinary excretion of its metabolites...
The concentrations of trichloroethylene in breath and blood and the urinary excretion of its metabolites following 30 minutes' direct immersion of one hand in the liquid, were compared with those...
Partition coefficients of some aromatic hydrocarbons and ketones in water, blood and oil.
Water/air, blood/air, oil/air, oil/water, and oil/blood partition (or solubility) coefficients of 17 aromatic hydrocarbons and ketones were measured by a newly developed vial-equilibration method,...
Sato, A, Nakajima, T, Koyama, Y
The activities of liver drug-metabolising enzymes for 16 aromatic or chlorinated hydrocarbons were measured in male rats after a three-week daily intake of ethanol amounting to 30% of total energy...
Effects of ethanol and phenobarbital treatments on the pharmacokinetics of toluene in rats.
Rats were exposed to toluene at a wide range of concentrations from 50 to 4000 ppm for six hours, and the effects of ethanol and phenobarbital (PB) treatments on the pharmacokinetics of toluene...
Ikatsu, H, Okino, T, Nakajima, T
Effects of chronic ethanol consumption and one day food deprivation on the hepatotoxicity of low dose carbon tetrachloride (CCl4; 0 to 100 ppm inhalation for eight hours) in rats were investigated by...
Long term course of change in anti-Yo antibody content in paraneoplastic cerebellar degeneration.
Tanaka, K, Tanaka, M, Igarashi, S, Onodera, O, Nakajima, T, Yamazaki, M, ...
Sarin poisoning of a rescue team in the Matsumoto sarin incident in Japan.
Nakajima, T, Sato, S, Morita, H, Yanagisawa, N
OBJECTIVES: A nerve agent sarin (isopropyl methyl phosphonofluoridate) was released in Matsumoto city, Japan, on 27 June 1994. About 600 people were affected by the sarin, including seven who died....
Ohmori, H, Ando, Y, Makita, Y, Onouchi, Y, Nakajima, T, Saraiva, M, ...
Minematsu, N, Nakamura, H, Iwata, M, Tateno, H, Nakajima, T, Takahashi, S, ...
Methods: 203 current or ex-smokers (lifelong cigarette consumption (CC) ≥10 pack years) with subclinical and established COPD phenotypes were clinically evaluated and pulmonary function tests and...
Doping control in Japan. An automated extraction procedure for the doping test.
Horse racing in Japan consists of two systems, the National (10 racecourses) and the Regional public racing (32 racecourses) having about 2,500 racing meetings in total per year. Urine or saliva...
Tumour necrosis factor-α in nasal allergy
Hisamatsu, K., Ganbo, T., Nakazawa, T., Nakajima, T., Ko, J., Goto, R., ...
Tumour necrosis factor-α (TNF-α) was measured by enzyme-linked immunosorbent assay and eosinophil cationic protein (ECP) by radio-immunoassay to evaluate TNF-α in nasal allergy. There was no...
The Effect of Lyso-PAF on Ciliary Activity of Human Paranasal Sinus Mucosa in vitro
Ganbo, T., Hisamatsu, K., Inoue, H., Nakajima, T., Murakami, Y.
The effect of lyso-PAF on ciliated cells was investigated in vitro. Normal mucosa was surgically obtained from human paranasal sinuses and incubated in the form of tissue culture. Ciliated epithelium...
Renal hypouricaemia in a patient with 48,XXYY syndrome.
Nakajima, H., Tajima, K., Nakajima, T., Iida, S., Sumi, S., Kono, N., ...
Studies on hypouricaemia observed in a patient with 48,XXYY syndrome revealed an abnormality in renal urate handling. His renal urate clearance was abnormally increased. Inosine administration and...
Imaizumi, T, Arikawa, T, Sato, T, Uesato, R, Matsumiya, T, Yoshida, H, ...
Interferon (IFN)-γ is a major cytokine that regulates T helper 1-type immune reactions and serves as an important mediator in the pathogenesis of autoimmune diseases. Retinoic acid-inducible gene-I...
Deletion mapping on chromosome 1p in well-differentiated gastric cancer.
Ezaki, T., Yanagisawa, A., Ohta, K., Aiso, S., Watanabe, M., Hibi, T., ...
To define the region on the short arm of chromosome 1 that is thought to include one or more tumour-suppressor genes for gastric cancers, we carried out loss of heterozygosity (LOH) studies in 26...
Kaira, K, Oriuchi, N, Imai, H, Shimizu, K, Yanagitani, N, Sunaga, N, ...
The clinical significance of L-type amino acid transporter 1 (LAT1) expression remains unclear, whereas many experimental studies have demonstrated that LAT1 is associated with the proliferation of...
Takeda, K, Negoro, S, Kudoh, S, Okishio, K, Masuda, N, Takada, M, ...
A study was undertaken to determine the maximum tolerated dose, the dose-limiting toxicities, and the response rate of irinotecan administered weekly with concurrent thoracic radiation therapy in...
Ohwada, S, Ikeya, T, Yokomori, T, Kusaba, T, Roppongi, T, Takahashi, T, ...
Iijima, H, Tomizawa, Y, Dobashi, K, Saito, R, Nakajima, T, Mori, M
We performed allelotyping analysis at nine regions on chromosome 3p using 56 microdissected samples from 23 primary lung adenocarcinomas to examine the process of progression within individual lung...