Boronate affinity saccharide electrophoresis: A novel carbohydrate analysis tool (2008)
Jackson, T. R., Springall, J. S., Rogalle, D., Masurnoto, N., Li, H. C., D'Hooge, F., ...
The incorporation of specialised carbohydrate affinity ligand methacrylamido phenylboronic acid in polyacrylamide gels for fluorophore-assisted carbohydrate electrophoresis greatly improved the...
A Three-Dimensional Stereotactic Neurosurgical Planner/Simulator (2007)
J. W. Snell, T. R. Jackson, W. T. Katz, K. Hinckley, J. C. Goble, N. F. Kassell
Abstract- We have designed and implemented a computer-based system for three-dimensional stereotactic planning of minimally invasive neurosurgical procedures. The system integrates rapid acquisition...
Components for Fabrication with Local Composition Control (2007)
T. R. Jackson, T. R. Jackson, H. Liu, H. Liu, N. M. Patrikalakis, N. M. Patrikalakis, ...
Solid Freeform Fabrication (SFF) processes have demonstrated the ability to produce parts with locally controlled composition. In the limit, processes such as 3D Printing can create parts with...
Mohapatra, A. K., Jackson, T. R., Adams, C. S.
We demonstrate coherent optical detection of highly excited Rydberg states (up to n=124) using electromagnetically induced transparency (EIT), providing a direct nondestructive probe of Rydberg...
Mohapatra, A. K., Jackson, T. R., Adams, C. S.
We observe electromagnetically induced transparency (EIT) on the 5s to 5p transition in a room temperature rubidium vapour cell by coupling the 5p state to a Rydberg state (ns or nd with n=26 to...
An Efficient Data Acquisition Methodology For Bandpass Sonar Signals (2006)
The function of a data acquisition system is to digitise data from a number of separate channels, and store these samples for later analysis. Sonar systems are typically multi-channel, and the...
Jones, D.T., Ganeshaguru, K., Anderson, R.J., Jackson, T.R., Bruckdorfer, K.R., Low, S.Y., ...
Activation of the phosphatidylinositol 3- kinase/AKT pathway antagonizes apoptosis in diverse cellular systems. We previously showed that human plasma activated AKT and potently blocked the ability...
Memory analysis of solid model representations for heterogeneous objects (2002)
T. R. Jackson, W. Cho, N. M. Patrikalakis, E. M. Sachs
Methods to represent and exchange parts consisting of Functionally Graded Material (FGM) for Solid Freeform Fabrication (SFF) with Local Composition Control (LCC) are evaluated based on their memory...
Methods for distributed design and fabrication of parts with local composition control (2001)
H. Wu, E. Sachs, N. Patrikalakis, D. Brancazio, J. Serdy, T. R. Jackson, ...
Solid Freeform Fabrication (SFF) technologies offer the potential to create parts with local control of the composition (LCC). This work develops the representations, methods, tools and design rules...
A Three-Dimensional Stereotactic Neurosurgical Planner/Simulator (1995)
Snell Jackson, J. W. Snell, T. R. Jackson, W. T. Katz, K. Hinckley, J. C. Goble, ...
Abstract - We have designed and implemented a computer-based system for three-dimensional stereotactic planning of minimally invasive neurosurgical procedures. The system integrates rapid acquisition...
Tissue Selective Magnetic Resonance Subtraction Venography (1995)
Jackson Snell, T. R. Jackson, J. W. Snell, J. C. Goble, E. R. Laws, N. F. Kassell
We have developed a procedure to image the major veins of the brain using three dimensional magnetic resonance imaging sequences. This procedure is based on the selective enhancement of blood vessels...
Hara, K, Yonezawa, K, Sakaue, H, Ando, A, Kotani, K, Kitamura, T, ...
Insulin stimulation drives the formation of a complex between tyrosine-phosphorylated insulin receptor substrate 1 (IRS-1) and 1-phosphatidylinositol 3-kinase (PI 3-kinase;...
Corey, S, Eguinoa, A, Puyana-Theall, K, Bolen, J B, Cantley, L, Mollinedo, F, ...
The signalling pathways used by the GM-CSF receptor are currently unknown. Here we show that in human myeloid derived cells GM-CSF can stimulate; (i) the accumulation of PtdIns(3,4,5)P3; (ii)...
Jackson, T R, Hallam, T J, Downes, C P, Hanley, M R
The addition of bradykinin to NG115-401L cells grown on coverslips results in the generation of rapid transient increases in intracellular [Ca2+] and inositol phosphates. Changes in intracellular...
Poyner, D R, Hanley, M R, Jackson, T R, Hawkins, P T
The activation of phosphoinositide 3-hydroxykinase (P13K) is currently believed to represent the critical regulatory event which leads to the production of a novel intracellular signal. We have...
Hawkins, P T, Poyner, D R, Jackson, T R, Letcher, A J, Lander, D A, Irvine, R F
1. The ability of myo-inositol polyphosphates to inhibit iron-catalysed hydroxyl radical formation was studied in a hypoxanthine/xanthine oxidase system [Graf, Empson and Eaton (1987) J. Biol. Chem....
Stephens, L, Jackson, T R, Hawkins, P T
PtdIns(4,5)P2 serves as a precursor of a diverse family of signalling molecules, including diacylglycerol (and hence phosphatidic acid), Ins(1,4,5)P3 [and hence Ins(1,3,4,5)P4] and PtdIns(3,4,5)P3....
Benton, H P, Jackson, T R, Hanley, M R
The inflammatory peptide bradykinin stimulated a rapid and transient increase in cytoplasmic [Ca2+] in primary pig chondrocytes, as measured by the fluorescent indicator dye Fura-2. This increase...
Jackson, T R, Patterson, S I, Thastrup, O, Hanley, M R
Thapsigargin, a sesquiterpene lactone with potent irritant and tumour-promoting activities, stimulates a rapid (within 15 s) transient increase in intracellular [Ca2+] in the NG115-401L neural cell...
Venkateswarlu, K, Oatey, P B, Tavaré, J M, Jackson, T R, Cullen, P J
Centaurin-alpha is a 46 kDa in vitro binding protein for the lipid second messenger PtdIns(3,4,5)P3. In this report we have addressed whether centaurin-alpha1, a human homologue of centaurin-alpha,...
Hara, K, Yonezawa, K, Sakaue, H, Ando, A, Kotani, K, Kitamura, T, ...
Insulin stimulation drives the formation of a complex between tyrosine-phosphorylated insulin receptor substrate 1 (IRS-1) and 1-phosphatidylinositol 3-kinase (PI 3-kinase;...
Corey, S, Eguinoa, A, Puyana-Theall, K, Bolen, J B, Cantley, L, Mollinedo, F, ...
The signalling pathways used by the GM-CSF receptor are currently unknown. Here we show that in human myeloid derived cells GM-CSF can stimulate; (i) the accumulation of PtdIns(3,4,5)P3; (ii)...
Jackson, T R, Hallam, T J, Downes, C P, Hanley, M R
The addition of bradykinin to NG115-401L cells grown on coverslips results in the generation of rapid transient increases in intracellular [Ca2+] and inositol phosphates. Changes in intracellular...
Poyner, D R, Hanley, M R, Jackson, T R, Hawkins, P T
The activation of phosphoinositide 3-hydroxykinase (P13K) is currently believed to represent the critical regulatory event which leads to the production of a novel intracellular signal. We have...
Hawkins, P T, Poyner, D R, Jackson, T R, Letcher, A J, Lander, D A, Irvine, R F
1. The ability of myo-inositol polyphosphates to inhibit iron-catalysed hydroxyl radical formation was studied in a hypoxanthine/xanthine oxidase system [Graf, Empson and Eaton (1987) J. Biol. Chem....
Stephens, L, Jackson, T R, Hawkins, P T
PtdIns(4,5)P2 serves as a precursor of a diverse family of signalling molecules, including diacylglycerol (and hence phosphatidic acid), Ins(1,4,5)P3 [and hence Ins(1,3,4,5)P4] and PtdIns(3,4,5)P3....
Benton, H P, Jackson, T R, Hanley, M R
The inflammatory peptide bradykinin stimulated a rapid and transient increase in cytoplasmic [Ca2+] in primary pig chondrocytes, as measured by the fluorescent indicator dye Fura-2. This increase...
Jackson, T R, Patterson, S I, Thastrup, O, Hanley, M R
Thapsigargin, a sesquiterpene lactone with potent irritant and tumour-promoting activities, stimulates a rapid (within 15 s) transient increase in intracellular [Ca2+] in the NG115-401L neural cell...
Venkateswarlu, K, Oatey, P B, Tavaré, J M, Jackson, T R, Cullen, P J
Centaurin-alpha is a 46 kDa in vitro binding protein for the lipid second messenger PtdIns(3,4,5)P3. In this report we have addressed whether centaurin-alpha1, a human homologue of centaurin-alpha,...