T. Rein

Evaluation of epigenetic effects of psychoactive drugs in primary astrocytes (2009)

Perisic, T., Zschocke, J., Kirmeier, T., Uhr, M., Asmus, M., Rein, T.

Lasting effects of chronic social stress in mice: impact of antidepressant treatment (2009)

Scharf, S., Sterlermann, V., Liebl, C., Ganea, K., Weber, P., Pütz, B., ...

XAP2 inhibits glucocorticoid receptor activity in mammalian cells (2009)

Laenger, A., Lang-Rollin, I., Kozany, C., Zschocke, J., Zimmermann, N., Ruegg, J., ...

Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks (2009)

Yehuda, R, Cai, G, Golier, J, Sarapas, C, Galea, S, Issing, M, ...

Peer Reviewed

Essential Role of Cofilin-1 in Regulating Thrombin-induced RelA/p65 Nuclear Translocation and Intercellular Adhesion Molecule 1 (ICAM-1) Expression in Endothelial Cells (2009)

Fazal, F., Bijli, K. M., Minhajuddin, M., Rein, T., Finkelstein, J. N., Rahman, A.

Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks (2009)

Yehuda, R., Cai, G. Q., Golier, J. A., Sarapas, C., Galea, S., Ising, M., ...

The novel stress inducible gene MPIP101 modulates neurite formation via changes in Actin dynamics (2009)

Schuelke, J. P., Liebl, C., Stiess, M., Zimmermann, N., Schmidt, M. V., Avrabos, C., ...

Biomarkers in a mouse model of posttraumatic stress disorder (2009)

Christian, L., Golub, Y., Rein, T., Wotjak, C. T., Schmidt, U.

Functional impact of FKBP5 on the phosphatase calcineurin (2009)

Gassen, N., Han, Y., Rein, T.

The involvement of FKBP5 in the behavioural and neuroendocrine effects of acute and chronic stress (2009)

Hartmann, J., Wagner, K., Liebl, C., Wolf, M., Scharf, S., Wang, X. D., ...

Modified antidepressants as innovative tools for identifying novel drug targets (2009)

Kirmeier, T., Ganal, V., Ranganath, G., Flachskamm, C., Maccarrone, G., Turck, C. W., ...

Steroid receptor folding and signaling is regulated by the Hsp70 cochaperones BAG-1 M and HspBP1 (2009)

Knapp, R. T., Konzany, C., Weidinger, E., Hafner, K., Holsboer, F., Hausch, F., ...

Can GR function be predicted from the relative cellular amounts of accessory proteins of the GR folding platform? (2009)

Lang-Rollin, I., Holsboer, F., Rein, T.

Functional analysis of a novel, stress-inducible transcript in the mouse brain (2009)

Liebl, C., Schmidt, M. V., Schülke, J. P., Avrabos, C., Trumbach, D., Eder, M., ...

Impact of lipid raft integrity on 5-HT3 receptor function and its modulation by antidepressants (2009)

Nothdurfter, C., Tanasic, S., Di Benedetto, B., Rammes, G., Kirmeier, T., Ganal, V., ...

The epigenetic status of the GLT-1 promoter is influenced by drugs with histone deacetylase inhibitor properties (2009)

Perisic, T., Rein, T., Zschocke, J.

The Munich PTSD Biomarker Study (MPBS) (2009)

Schmidt, U., Gall-Kleebach, D., Pfister, H., Czesny, N., Spoormaker, V. I., Rein, T., ...

Deletion of FKBP5 alters stress-related parameters in mice (2009)

Schmidt, U., Touma, C., Gassen, N., Christian, L., Asmus, S., Cox, M. B., ...

The novel stress inducible gene MPIP101 modulates neurite formation via changes in Actin dynamics (2009)

Schülke, J. P., Liebl, C., Stiess, M., Zimmermann, N., Schmidt, M. V., Avrabos, C., ...

Characterisation of DNA methylation marks in stress exposed hippocampal astrocytes (2009)

Zimmermann, N., Zschocke, J., Bettecken, T., Pütz, B., Holsboer, F., Rein, T.

Profiling of stress-induced epigenetic alterations in neuronal Neuro-2a cells (2009)

Zschocke, J., Rein, T.

Representation, Coding, and Rendering of 3D Video Objects with MPEG-4 and H.264/AVC (2008)

A. Smolić, K. Mueller, P. Merkle, T. Rein, M. Kautzner, P. Eisert, ...

Abstract—3D video objects provide the same functionalities as virtual computer graphics objects but depict the motion and appearance of real world moving objects. They can be viewed interactively...

Acute stress regulation of neuroplasticity genes in mouse hippocampus CA3 area - Possible novel signalling pathways (2008)

Tsolakidou, A., Trumbach, D., Panhuysen, M., Pütz, B., Deussing, J., Wurst, W., ...

Role of the hsp70 cochaperone BAG1 in glucocorticoid receptor function and stress-related diseases (2008)

Schmidt, U., Holsboer, F., Rein, T.

Proteomic search for intrcellular binding sites of antidepressants (2007)

Kirmeier, T., Fessler, B., Wochnik-Veltrup, G., Kozany, C., Kimura, M., Hausch, F., ...

The hsp70 cochaperones BAG-1 M and HspBP1 as possible cause for glucocorticoid resistance (2007)

Knapp, R. T., Holsboer, F., Rein, T.

The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction (2007)

Liberman, A. C., Refojo, D., Druker, J., Toscano, M., Rein, T., Holsboer, F., ...

Analysis of gene expression and regulation of a novel, stress-inducible transcript in the mouse (2007)

Liebl, C., Schuelke, J., Schmidt, M. V., Truembach, D., Rein, T., Müller, M. B.

Functional Consequences of the accumulation of psychopharmacological drugs in "lipid rafts" on ligand-gated ion channels (2007)

Nothdurfter, C., Eisensamer, B., Rein, T., Rammes, G., Uhr, M., Henes, K., ...

Pitfalls in isolating lipid rafts (2007)

Nothdurfter, C., Rammes, G., Rein, T., Rupprecht, R.

Differential effects of TPR proteins on steroid receptor signaling (2007)

Wochnik, G., Schuelke, J., Lang-Rollin, I., Berning, B., Rein, T.

Epigenetic regulation of the human EAAT2 gene expression in glioma cells and normal brain (2007)

Zschocke, J., Allritz, C., Engele, J., Rein, T.

DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells (2007)

Zschocke, J., Allritz, C., Engele, J., Rein, T.

SNPs in FKBP5 determine a novel subtype of depression characterized by rapid response to antidepressant treatment (2006)

Binder, E. B., Lucae, S., Salyakina, D., Lichtner, P., Meitinger, T., Bondy, B., ...

Cross-talk of vitamin D and glucocorticoids in hippocampal cells (2006)

Obradovic, D., Gronemeyer, H., Lutz, B., Rein, T.

Proteomic search for intracellular binding sites of antidepressants (2005)

Kirmeier, T., Turck, C. W., Holsboer, F., Rein, T.

Effects of TPR proteins on steroid receptor signaling (2005)

Lang-Rollin, I. C., Wochnik, G. M., Holsboer, F., Rein, T.

Antagonizing actions of vitamin D3 on glucocorticoid functions in hippocampal cells (2005)

Obradovic, D., Lutz, B., Grönemeyer, H., Lutz, B., Rein, T.

Identification of stress-regulated genes in the brain of two mouse strains that differ in the antidepressant responsiveness (2005)

Tsolakidou, A., Panhuysen, M., Sillaber, I., Pütz, B., Holsboer, E., Rein, T.

The role of FKBP51 in the regulation of the glucocorticoid receptor (2005)

Wochnik, G. M., Binder, E. B., Salyakina, D., Kohli, M. A., Kloiber, S., Holsboer, F., ...

Inhibition of GR-mediated transcription by p23 requires interaction with Hsp90 (2004)

Wochnik,G. M., Young,J. C., Schmidt,U., Holsboer,F., Hartl,F. U., Rein,T.

Inhibition of GR-mediated transcription by p23 requires interaction with Hsp90 (2004)

Wochnik, G. M., Young, J. C., Schmidt, U., Holsboer, F., Hartl, F. U., Rein, T.

DNA methylation may restrict but does not determine differential gene expression at the Sgy/Tead2 locus during mouse development (2004)

Kaneko, K. J., Rein, T., Guo, Z. S., Latham, K., DePamphilis, M. L.

Inhibition of GR-mediated transcription by p23 requires interaction with Hsp90 (2004)

Wochnik, G. M., Young, J. C., Schmidt, U., Holsboer, F., Hartl, F. U., Rein, T.

Representation, coding, and rendering of 3D video objects with MPEG-4 and H.264/AVC (2004)

Smolic, A., Mueller, K., Merkle, P., Rein, T., Kautzner, M., Eisert, P., ...

3D video objects provide the same functionalities as virtual computer graphics objects but depict the motion and appearance of real world moving objects. They can be viewed interactively from any...

Free viewpoint video extraction, representation, coding, and rendering (2004)

Smolic, A., Mueller, K., Merkle, P., Rein, T., Kautzner, M., Eisert, P., ...

Free viewpoint video provides the possibility to freely navigate within dynamic real world video scenes by choosing arbitrary viewpoints and view directions. So far, related work only considered free...

Octree voxel modeling with multi-view texturing in cultural heritage scenarios (2004)

Müller, K., Smolic, A., Kaspar, B., Merkle, P., Rein, T., Eisert, P., ...

Reconstructuion of 3D models of real world scenes and objects and photos realistic rendering in interactive free viewpoint applicadtions is challenging task combining image processing, computer...

Polymorphisms in FKBP5, a co-chaperone of the glucocorticoid receptor are associated with response to antidepressant drugs (2004)

Binder, E. B., Salyakina, D., Wochnik, G., Ising, M., Pütz, B., Kern, N., ...

Free viewpoint video extraction, representation, coding and rendering (2004)

A. Smolic, K. Mueller, P. Merkle, T. Rein, M. Kautzner, P. Eisert, ...

Free viewpoint video provides the possibility to freely navigate within dynamic real world video scenes by choosing arbitrary viewpoints and view directions. So far, related work only considered free...

The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation (2003)

Rosenhagen,M. C., Soti,C., Schmidt,U., Wochnik,G. M., Hartl,F. U., Holsboer,F., ...

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system (2003)

Brychzy,A., Rein,T., Winklhofer,K. F., Hartl,F. U., Young,J. C., Obermann,W. M. J.

Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor (2003)

Schmidt,U., Wochnik,G. M., Rosenhagen,M. C., Young,J. C., Hartl,F. U., Holsboer,F., ...

The co-chaperone BAG-1 is involved in the regulation of steroid hormone receptors, including the glucocorticoid receptor (GR). More recently, BAG-1 was found in the nucleus where it decreases GR...

Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor (2003)

Schmidt, U, Wochnik, GM, Rosenhagen, MC, Young, JC, Hartl, FU, Holsboer, F, ...

The co-chaperone BAG-1 is involved in the regulation of steroid hormone receptors, including the glucocorticoid receptor (GR). More recently, BAG-1 was found in the nucleus where it decreases GR...

Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor (2003)

Schmidt, U., Wochnik, G. M., Rosenhagen, M. C., Young, J. C., Hartl, F. U., Holsboer, F., ...

The co-chaperone BAG-1 is involved in the regulation of steroid hormone receptors, including the glucocorticoid receptor (GR). More recently, BAG-1 was found in the nucleus where it decreases GR...

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system (2003)

Brychzy, A., Rein, T., Winklhofer, K. F., Hartl, F. U., Young, J. C., Obermann, W. M. J.

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system (2003)

Brychzy, A., Rein, T., Winklhofer, K. F., Hartl, F. U., Young, J. C., Obermann, W. M. J.

Antidepressants differentially influence the transcriptional activity of the glucocorticoid receptor in vitro (2003)

Herr, A. S., Tsolakidou, A., Yassouridis, A., Holsboer, F., Rein, T.

Role of chaperones in signal transduction of the glucocorticoid receptor (2003)

Rein, T., Wochnik, G. M., Schmidt, U., Rosenhagen, M., Holsboer, F.

A functional genetic screen to identify factors involved in glucocorticoid receptor (GR) transactivation (2003)

Rüegg, J., Holsboer, F., Rein, T.

The co-chaperone BAG-1 as a candidate for causing cortisteroid receptor resistance: A detailed mutational analysis (2003)

Schmidt, U., Rosenhagen, M., Holsboer, F., Rein, T.

FKBP51 and FKBP52 differentially regulate corticosteroid receptors at distinct levels: Importance of the peptidylprolyl isomerase domain (2003)

Wochnik, G. M., Abel, A., Schmidt, U., Holsboer, F., Rein, T.

The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation (2003)

Rosenhagen, M. C., Soti, C., Schmidt, U., Wochnik, G. M., Hartl, F. U., Holsboer, F., ...

Cisplatin inhibits glucocorticoid receptor activation by binding to heat shock protein 90 (2002)

Rosenhagen, M, Schmidt, U, Wochnik, G, Holsboer, F, Rein, T

The co-chaperone BAG-1 as a candidate for causing cortisteroid receptor resistance: A detailed mutational analysis (2002)

Schmidt, U, Rosenhagen, M, Holsboer, F, Rein, T

Activity of the GR in G2 and mitosis (2002)

Abel, GA, Wochnik, GM, Ruegg, J, Rouyer, A, Holsboer, F, Rein, T

To elucidate the mechanisms mediating the reported transient physiological glucocorticoid resistance in G2/M cell cycle phase, we sought to establish a model system of glucocorticoid- resistant cells...

Synergistic inhibition of the glucocorticoid receptor by radicicol and benzoquinone ansamycins. (2001)

Rosenhagen, M. C., Young, J. C., Wochnik, G. M., Herr, A. S., Schmidt, U., Hartl, F. U., ...

Rifampicin is not an activator of glucocorticoid receptor. (2000)

Herr, A. S., Wochnik, G. M., Rosenhagen, M. C., Holsboer, F., Rein, T.

Identifying 5-methylcytosine and related modifications in DNA genomes (1998)

Rein, T, DePamphilis, ML, Zorbas, H

Identifying 5-methylcytosine and related modifications in DNA genomes.

Rein, T, DePamphilis, M L, Zorbas, H

Intense interest in the biological roles of DNA methylation, particularly in eukaryotes, has produced at least eight different methods for identifying 5-methylcytosine and related modifications in...

YY1 and NF1 both activate the human p53 promoter by alternatively binding to a composite element, and YY1 and E1A cooperate to amplify p53 promoter activity.

Furlong, E E, Rein, T, Martin, F

A novel transcription factor binding element in the human p53 gene promoter has been characterized. It lies about 100 bp upstream of the major reported start site for human p53 gene transcription. On...

Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.

Rein, T, Zorbas, H, DePamphilis, M L

ori-beta is a well-characterized origin of bidirectional replication (OBR) located approximately 17 kb downstream of the dihydrofolate reductase gene in hamster cell chromosomes. The approximately...

In vivo footprinting of the IRF-1 promoter: inducible occupation of a GAS element next to a persistent structural alteration of the DNA.

Rein, T, Müller, M, Zorbas, H

GAS (gamma activated sequence) and GAS-like elements are found in a rapidly growing number of genes. Data from EMSA (electromobility shift assay) and transient transfection assays using heterologous...

Complete cDNA sequence encoding the B subunit of human factor XIII.

Grundmann, U, Nerlich, C, Rein, T, Zettlmeissl, G

Transfer-RNA interferes with the uniform cleavage pattern of DNA by hydroxyl radicals.

Zorbas, H, Rein, T, Winnacker, E L

Complete cDNA sequence encoding human beta-galactoside alpha-2,6-sialyltransferase.

Grundmann, U, Nerlich, C, Rein, T, Zettlmeissl, G

Isolation of cDNA coding for the placental protein 15 (PP15).

Grundmann, U, Nerlich, C, Rein, T, Lottspeich, F, Küpper, H A

Cloning of cDNA encoding human placental protein 12 (PP12): binding protein for IGF I and somatomedin.

Grundmann, U, Nerlich, C, Bohn, H, Rein, T

Identifying 5-methylcytosine and related modifications in DNA genomes.

Rein, T, DePamphilis, M L, Zorbas, H

Intense interest in the biological roles of DNA methylation, particularly in eukaryotes, has produced at least eight different methods for identifying 5-methylcytosine and related modifications in...

YY1 and NF1 both activate the human p53 promoter by alternatively binding to a composite element, and YY1 and E1A cooperate to amplify p53 promoter activity.

Furlong, E E, Rein, T, Martin, F

A novel transcription factor binding element in the human p53 gene promoter has been characterized. It lies about 100 bp upstream of the major reported start site for human p53 gene transcription. On...

Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.

Rein, T, Zorbas, H, DePamphilis, M L

ori-beta is a well-characterized origin of bidirectional replication (OBR) located approximately 17 kb downstream of the dihydrofolate reductase gene in hamster cell chromosomes. The approximately...

In vivo footprinting of the IRF-1 promoter: inducible occupation of a GAS element next to a persistent structural alteration of the DNA.

Rein, T, Müller, M, Zorbas, H

GAS (gamma activated sequence) and GAS-like elements are found in a rapidly growing number of genes. Data from EMSA (electromobility shift assay) and transient transfection assays using heterologous...

Complete cDNA sequence encoding the B subunit of human factor XIII.

Grundmann, U, Nerlich, C, Rein, T, Zettlmeissl, G

Transfer-RNA interferes with the uniform cleavage pattern of DNA by hydroxyl radicals.

Zorbas, H, Rein, T, Winnacker, E L

Complete cDNA sequence encoding human beta-galactoside alpha-2,6-sialyltransferase.

Grundmann, U, Nerlich, C, Rein, T, Zettlmeissl, G

Isolation of cDNA coding for the placental protein 15 (PP15).

Grundmann, U, Nerlich, C, Rein, T, Lottspeich, F, Küpper, H A

Cloning of cDNA encoding human placental protein 12 (PP12): binding protein for IGF I and somatomedin.

Grundmann, U, Nerlich, C, Bohn, H, Rein, T