Taewon Lee

Testing for treatment effects on gene ontology (2008)

Lee, Taewon, Desai, Varsha G, Velasco, Cruz, Reis, Robert, Delongchamp, Robert R

Abstract In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functional...

Designing Toxicogenomics Studies that use DNA Array Technology (2008)

Robert R. Delongchamp, Cruz Velasco, Varsha G. Desai, Taewon Lee, James C. Fuscoe

Background: Bioassays are routinely used to evaluate the toxicity of test agents. Experimental designs for bioassays are largely encompassed by fixed effects linear models. In toxicogenomics studies...

Significance analysis of groups of genes in expression profiling studies (2007)

Chen, James J., Lee, Taewon, Delongchamp, Robert R., Chen, Tao, Tsai, Chen-An

Motivation: Gene class testing (GCT) is a statistical approach to determine whether some functionally predefined classes of genes express differently under two experimental conditions. GCT computes...

A method for computing the overall statistical significance of a treatment effect among a group of genes (2006)

Delongchamp, Robert, Lee, Taewon, Velasco, Cruz

Abstract Background In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be grouped by a...

Errors in Numerical Solutions of Spherically Symmetric Shock Physics Problems (1998)

Glimm, James, Grove, John W., Kang, Yunghee, Lee, Taewon, Li, Xiaolin

The authors seek robust and understandable error models for shock physics simulations. The purpose of this paper is to explore complications introduced by spherical flow in the analysis of errors in...

Testing for treatment effects on gene ontology

Lee, Taewon, Desai, Varsha G, Velasco, Cruz, Reis, Robert JS, Delongchamp, Robert R

In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functional category such...

Association of Polymorphisms in Monocyte Chemoattractant Protein-1 Promoter with Diabetic Kidney Failure in Korean Patients with Type 2 Diabetes Mellitus

Moon, Ju-young, Jeong, Laeik, Lee, Sangho, Jeong, Kyunghwan, Lee, Taewon, Ihm, Chun-Gyoo, ...

Monocyte chemoattractant protein-1 (MCP-1) is suggested to be involved in the progression of diabetic nephropathy. We investigated the association of the -2518 A/G polymorphism in the MCP-1 gene with...