Takahiro Nakayama

Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading (2007)

Nakayama, Takahiro, Nishioka, Kenichi, Dong, Yi-Xin, Shimojima, Tsukasa, Hirose, Susumu

Epigenetic maintenance of the expression state of the genome is critical for development. Drosophila GAGA factor interacts with FACT and modulates chromatin structure for the maintenance of gene...

Human peripheral blood mononuclear cells enhance cell-cell interaction between human endometrial epithelial cells and BeWo-cell spheroids (2003)

Kosaka, Kenzo, Fujiwara, Hiroshi, Tatsumi, Keiji, Yoshioka, Shinya, Higuchi, Toshihiro, Sato, Yukiyasu, ...

BACKGROUND: Previously, it was reported that T‐lymphocytes derived from non‐pregnant mice promote murine embryo implantation. In order to examine the immunological regulation of endometrial...

Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor (2003)

Shimojima, Tsukasa, Okada, Masahiro, Nakayama, Takahiro, Ueda, Hitoshi, Okawa, Katsuya, Iwamatsu, Akihiro, ...

Chromatin structure plays a critical role in the regulation of transcription. Drosophila GAGA factor directs chromatin remodeling to its binding sites. We show here that Drosophila FACT (facilitates...

Human peripheral blood mononuclear cells (PBMC) in early pregnancy promote embryo invasion in vitro: HCG enhances the effects of PBMC (2002)

Nakayama, Takahiro, Fujiwara, Hiroshi, Maeda, Michiyuki, Inoue, Takuya, Yoshioka, Shinya, Mori, Takahide, ...

BACKGROUND: The aim of this study was to investigate the role of peripheral blood mononuclear cells (PBMC) in embryo invasion at the implantation site and to estimate the effect on PBMC function of...

Peripheral blood mononuclear cells in early pregnancy promote invasion of human choriocarcinoma cell line, BeWo cells (2002)

Egawa, Haruto, Fujiwara, Hiroshi, Hirano, Takeshi, Nakayama, Takahiro, Higuchi, Toshihiro, Tatsumi, Keiji, ...

BACKGROUND: During the establishment of the maternal blood circulation around the implanting human embryo, maternal peripheral blood mononuclear cells (PBMC) directly contact trophoblasts. To...

Human granulosa cells express integrin {alpha}2 and collagen type IV: possible involvement of collagen type IV in granulosa cell luteinization (1999)

Yamada, Shigetoshi, Fujiwara, Hiroshi, Honda, Tetsuro, Higuchi, Toshihiro, Nakayama, Takahiro, Inoue, Takuya, ...

Previously, it has been shown that integrin α6β1 expressed on human granulosa cells regulates luteinization in co-operation with its ligand, laminin. In this study, integrin α2 was...

Expression of calcium binding protein D-9k messenger RNA in the mouse uterine endometrium during implantation (1999)

Tatsumi, Keiji, Higuchi, Toshihiro, Fujiwara, Hiroshi, Nakayama, Takahiro, Itoh, Katsuhiko, Mori, Takahide, ...

To investigate the molecular mechanisms of implantation, we constructed a cDNA library of mouse uteri enriched with pregnancy-induced genes by subtractive hybridization and polymerase chain reaction...

Dielectric Breakdown Properties of Ta2O5/SiO2 Stacked Thin Films Prepared by r.f. Sputtering. (1998)

Onisawa, Ken-ichi, Abe, Yoshio, Nakayama, Takahiro, Fuyama, Moriaki, Ono, Yoshimasa A.

Dielectric thin films of the stacked Ta2O5/SiO2 type were deposited on indium tin oxide coated glass substrates by the r.f. magnetron sputtering method. The effective dielectric constant epsilon rT...

Administration of thymocytes derived from non-pregnant mice induces an endometrial receptive stage and leukaemia inhibitory factor expression in the uterus (1998)

Fujita, Kazuyuki, Nakayama, Takahiro, Takabatake, Keiko, Higuchi, Toshihiro, Fujita, Jun, Maeda, Michiyuki, ...

We have previously reported that intravenous administration of splenocytes prepared from mice in the early stages of pregnancy promoted embryo implantation in pseudopregnant mice. Since a...

Ovary and Ovulation: An aminopeptidase inhibitor, bestatin, enhances gonadotrophin-stimulated ovulation in mice (1996)

Nakamura, Kimihiko, Fujiwara, Hiroshi, Nakayama, Takahiro, Goto, Yasuo, Tachibana, Toshiyuki, Suginami, Hiroshi, ...

The role of aminopeptidases in follicular growth and/or ovulation in vivo was examined. We injected an inhibitor of cell-surface aminopeptidases, bestatin (4 mg/ml, 100 μl), i.p. four times...

The use of intra-endometrial embryo transfer for increasing the pregnancy rate (1995)

Nakayama, Takahiro, Goto, Yasuo, Kanzaki, Hideharu, Takabatake, Keiko, Himeno, Takao, Noda, Yoichi, ...

It has been demonstrated previously that pregnancy can be achieved by the direct insertion of embryos into the endometrial stroma (intra-endometrial embryo transfer) of mice. In this study we...

Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor

Shimojima, Tsukasa, Okada, Masahiro, Nakayama, Takahiro, Ueda, Hitoshi, Okawa, Katsuya, Iwamatsu, Akihiro, ...

Chromatin structure plays a critical role in the regulation of transcription. Drosophila GAGA factor directs chromatin remodeling to its binding sites. We show here that Drosophila FACT (facilitates...

Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor

Shimojima, Tsukasa, Okada, Masahiro, Nakayama, Takahiro, Ueda, Hitoshi, Okawa, Katsuya, Iwamatsu, Akihiro, ...

Chromatin structure plays a critical role in the regulation of transcription. Drosophila GAGA factor directs chromatin remodeling to its binding sites. We show here that Drosophila FACT (facilitates...

Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading

Nakayama, Takahiro, Nishioka, Kenichi, Dong, Yi-Xin, Shimojima, Tsukasa, Hirose, Susumu

Epigenetic maintenance of the expression state of the genome is critical for development. Drosophila GAGA factor interacts with FACT and modulates chromatin structure for the maintenance of gene...

Lowering Blood Pressure Blocks Mesangiolysis and Mesangial Nodules, but Not Tubulointerstitial Injury, in Diabetic eNOS Knockout Mice

Kosugi, Tomoki, Heinig, Marcelo, Nakayama, Takahiro, Connor, Thomas, Yuzawa, Yukio, Li, Qiuhong, ...

Recently, we and others reported that diabetic endothelial nitric oxide synthase knockout (eNOSKO) mice develop advanced glomerular lesions that include mesangiolysis and nodular lesions....