Takahisa Ikegami

structure of the transcriptional coactivator (2008)

Jun Ozaki, Ken-ichi Takemaru, Takahisa Ikegami, Masaki Mishima, Hitoshi Ueda, Susumu Hirose, ...

Identification of the core domain and the secondary

Identification of the Substrate Interaction Region of the Chitin-Binding Domain of Streptomyces griseus Chitinase C (2006)

Akagi, Ken-ichi, Watanabe, Jun, Hara, Masashi, Kezuka, Yuichiro, Chikaishi, Eriko, Yamaguchi, Tohru, ...

Chitinase C from Streptomyces griseus HUT6037 was discovered as the first bacterial chitinase in family 19 other than chitinases found in higher plants. Chitinase C comprises two domains: a...

A Novel Way to Express Proline-Selectively Labeled Proteins with a Wheat Germ Cell-Free Protein Synthesis System (2006)

Shimizu, Masato, Ikegami, Takahisa, Akiyama, Koichi, Morita, Eugene Hayato

For high-throughput protein structural analyses, it is essential to develop a reliable protein overexpression system. Although many protein overexpression systems, such as ones involving Escherichia...

A Novel Way to Express Proline-Selectively Labeled Proteins with a Wheat Germ Cell-Free Protein Synthesis System (2006)

Shimizu, Masato, Ikegami, Takahisa, Akiyama, Koichi, Morita, Eugene Hayato

For high-throughput protein structural analyses, it is essential to develop a reliable protein overexpression system. Although many protein overexpression systems, such as ones involving Escherichia...

NMR structure of the DNA decamer duplex containing double T{middle dot}G mismatches of cis-syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC-hHR23B complex (2004)

Lee, Joon-Hwa, Park, Chin-Ju, Shin, Jae-Sun, Ikegami, Takahisa, Akutsu, Hideo, Choi, Byong-Seok

The cis–syn cyclobutane pyrimidine dimer (CPD) is a cytotoxic, mutagenic and carcinogenic DNA photoproduct and is repaired by the nucleotide excision repair (NER) pathway in mammalian cells. The...

Resonance Assignments, Solution Structure, and Backbone Dynamics of the DNA- and RPA-Binding Domain of Human Repair Factor XPA (1999)

Ikegami, Takahisa, Kuraoka, Isao, Saijo, Masafumi, Kodo, Naohiko, Kyogoku, Yoshimasa, Morikawa, Kosuke, ...

XPA is involved in the damage recognition step of nucleotide excision repair (NER). XPA binds to other repair factors, and acts as a key element in NER complex formation. The central domain of human...

Expression and Characterization of the Chitin-Binding Domain of Chitinase A1 from Bacillus circulans WL-12

Hashimoto, Masayuki, Ikegami, Takahisa, Seino, Shizuka, Ohuchi, Nobuhumi, Fukada, Harumi, Sugiyama, Junji, ...

Chitinase A1 from Bacillus circulans WL-12 comprises an N-terminal catalytic domain, two fibronectin type III-like domains, and a C-terminal chitin-binding domain (ChBD). In order to study the...

NMR structure of the DNA decamer duplex containing double T·G mismatches of cis–syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC–hHR23B complex

Lee, Joon-Hwa, Park, Chin-Ju, Shin, Jae-Sun, Ikegami, Takahisa, Akutsu, Hideo, Choi, Byong-Seok

The cis–syn cyclobutane pyrimidine dimer (CPD) is a cytotoxic, mutagenic and carcinogenic DNA photoproduct and is repaired by the nucleotide excision repair (NER) pathway in mammalian cells. The...

Regulation of Bin1 SH3 domain binding by phosphoinositides

Kojima, Chie, Hashimoto, Ari, Yabuta, Izumi, Hirose, Mayumi, Hashimoto, Shigeru, Kanaho, Yasunori, ...

Bin1/M-amphiphysin-II is an amphiphysin-II isoform highly expressed in transverse tubules of adult striated muscle and is implicated in their biogenesis. Bin1 contains a basic unique amino-acid...

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis

Hashimoto, Shigeru, Hirose, Mayumi, Hashimoto, Ari, Morishige, Masaki, Yamada, Atsuko, Hosaka, Harumi, ...

Invasive potentials of carcinomas greatly contribute to their metastasis, which is a major threat in most cancers. We have recently shown that Arf6 plays a pivotal role in breast cancer invasive...

Expression and Characterization of the Chitin-Binding Domain of Chitinase A1 from Bacillus circulans WL-12

Hashimoto, Masayuki, Ikegami, Takahisa, Seino, Shizuka, Ohuchi, Nobuhumi, Fukada, Harumi, Sugiyama, Junji, ...

Chitinase A1 from Bacillus circulans WL-12 comprises an N-terminal catalytic domain, two fibronectin type III-like domains, and a C-terminal chitin-binding domain (ChBD). In order to study the...

NMR structure of the DNA decamer duplex containing double T·G mismatches of cis–syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC–hHR23B complex

Lee, Joon-Hwa, Park, Chin-Ju, Shin, Jae-Sun, Ikegami, Takahisa, Akutsu, Hideo, Choi, Byong-Seok

The cis–syn cyclobutane pyrimidine dimer (CPD) is a cytotoxic, mutagenic and carcinogenic DNA photoproduct and is repaired by the nucleotide excision repair (NER) pathway in mammalian cells. The...

Regulation of Bin1 SH3 domain binding by phosphoinositides

Kojima, Chie, Hashimoto, Ari, Yabuta, Izumi, Hirose, Mayumi, Hashimoto, Shigeru, Kanaho, Yasunori, ...

Bin1/M-amphiphysin-II is an amphiphysin-II isoform highly expressed in transverse tubules of adult striated muscle and is implicated in their biogenesis. Bin1 contains a basic unique amino-acid...

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis

Hashimoto, Shigeru, Hirose, Mayumi, Hashimoto, Ari, Morishige, Masaki, Yamada, Atsuko, Hosaka, Harumi, ...

Invasive potentials of carcinomas greatly contribute to their metastasis, which is a major threat in most cancers. We have recently shown that Arf6 plays a pivotal role in breast cancer invasive...