Kuroki, Hiroshi, Nakagawa, Yasuaki, Mori, Koji, Kobayashi, Masahiko, Yasura, Ko, Okamoto, Yukihiro, ...
No abstract available.
Subaxial subluxation after atlantoaxial transarticular screw fixation in rheumatoid patients (2009)
Ito, Hiromu, Neo, Masashi, Sakamoto, Takeshi, Fujibayashi, Shunsuke, Yoshitomi, Hiroyuki, Nakamura, Takashi
The most common cervical abnormality associated with rheumatoid arthritis (RA) is atlantoaxial subluxation, and atlantoaxial transarticular screw fixation has proved to be one of the most reliable,...
Homhuan, Atthachai, Kogure, Kentaro, Nakamura, Takashi, Shastri, Nilabh, Harashima, Hideyoshi
To improve uptake and cross-presentation of exogenous antigens (Ag) by dendritic cells (DCs), octaarginine-modified liposomes (R8-Lip) were used as a novel strategy for protein-Ag transduction....
Ando, Masaki, Kawamura, Seiji, Sato, Shuichi, Nakamura, Takashi, Tsubono, Kimio, Araya, Akito, ...
DECIGO pathfinder (DPF) is a milestone satellite mission for DECIGO (DECi-hertz Interferometer Gravitational wave Observatory), which is a future space gravitational wave antenna. DECIGO is expected...
Decrease of Cadmium Accumulation in Crops by Zero-valent Iron (2009)
Watanabe, Toshihiro, Nakamura, Takashi, Murata, Yasutoshi, Sakai, Yuki, Osaki, Mitsuru
Cadmium (Cd) contamination in soils is a serious problem for crop production in the world. Zero-valent iron (Fe(0)) is a reactive material with reducing power capable of stabilizing toxic elements,...
Zeros and the universality for the Euler-Zagier-Hurwitz type of multiple zeta-functions (2009)
In this paper, we show relations between the zero-free region and the universality for the Euler–Zagier–Hurwitz type of multiple zeta-functions. Roughly speaking these relations imply that we can...
Aerodynamic Optimization of Transonic Wing Design Based on Evolutionary Algorithm (2008)
Akira Oyama, Shigeru Obayashi, Kazuhiro Nakahashi, Takashi Nakamura
ABSTRACT: Evolutionary Algorithm (EA) is applied to a practical three-dimensional shape optimization for aerodynamic design of an aircraft wing. Aerodynamic performances of the design candidates are...
Riemann zeta-values, Euler polynomials and the best constant of Sobolev inequality (2008)
MI: Global COE Program Education-and-Research Hub for Mathematics-for-Industry
Some topics related to Hurwitz-Lerch zeta functions (2008)
MI: Global COE Program Education-and-Research Hub for Mathematics-for-Industry
Statistical Properties of Gamma-Ray Burst Polarization (2008)
Toma, Kenji, Sakamoto, Takanori, Zhang, Bing, Hill, Joanne E., McConnell, Mark L., Bloser, Peter F., ...
The emission mechanism and the origin and structure of magnetic fields in gamma-ray burst (GRB) jets are among the most important open questions concerning the nature of the central engine of GRBs....
Tsutsui, Ryo, Nakamura, Takashi, Yonetoku, Daisuke, Murakami, Toshio, Kodama, Yoshiki, Takahashi, Keitaro
We consider two empirical relations using data only from the prompt emission of Gamma-Ray Bursts (GRBs), peak energy ($E_p$) - peak luminosity ($L_p$) relation (so called Yonetoku relation) and...
Ando, Masaki, Kawamura, Seiji, Nakamura, Takashi, Tsubono, Kimio, Tanaka, Takahiro, Funaki, Ikkoh, ...
DECIGO pathfinder (DPF) is a milestone satellite mission for DECIGO (DECi-hertz Interferometer Gravitational wave Observatory) which is a future space gravitational wave antenna. DECIGO is expected...
The Japanese space gravitational wave antenna; DECIGO (2008)
Kawamura, Seiji, Ando, Masaki, Nakamura, Takashi, Tsubono, Kimio, Tanaka, Takahiro, Funaki, Ikkoh, ...
DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese space gravitational wave antenna. DECIGO is expected to open a new window of observation for gravitational...
Constraints on $w_0$ and $w_a$ of Dark Energy from High Redshift Gamma Ray Bursts (2008)
Tsutsui, Ryo, Nakamura, Takashi, Yonetoku, Daisuke, Murakami, Toshio, Tanabe, Sachiko, Kodama, Yoshiki, ...
We extend the Hubble diagram up to $z = 5.6$ using 63 gamma-ray bursts (GRBs) via peak energy-peak luminosity relation (so called Yonetoku relation), and obtain constraints on cosmological parameters...
Kuroki, Hiroshi, Nakagawa, Yasuaki, Mori, Koji, Kobayashi, Masahiko, Yasura, Ko, Okamoto, Yukihiro, ...
Abstract Introduction There is a lack of data relating the macroscopic appearance of cartilage to its ultrasound properties. The purpose of the present study was to evaluate degenerated cartilage and...
Takashi Nakamura, Hideo Yamasaki
Reef-building corals inhabit a variety of aquatic habitats with a range of light conditions. Because the coral host depends on photosynthetic products assimilated from endosymbiotic algae,...
Kodama, Yoshiki, Yonetoku, Daisuke, Murakami, Toshio, Tanabe, Sachiko, Tsutsui, Ryo, Nakamura, Takashi
We calibrated the peak energy-peak luminosity relation of GRBs (so called Yonetoku relation) using 33 events with the redshift $z < 1.62$ without assuming any cosmological models. The luminosity...
Murase, Kohta, Ioka, Kunihito, Nagataki, Shigehiro, Nakamura, Takashi
Gamma-ray bursts (GRBs) are one of the candidates of ultra-high-energy (around 10^18.5 eV) cosmic-ray (UHECR) sources. We investigate high-energy cosmic-ray acceleration including heavy nuclei in...
PET fiber fabrics modified with bioactive titanium oxide for bone substitutes (2008)
Kokubo, Tadashi, Ueda, Takahiro, Kawashita, Masakazu, Ikuhara, Yuichi, Takaoka, Gikan H., Nakamura, Takashi
DETERMINATION OF PHYSICOCHEMICAL PROPERTIES OF TETRABROMOBISPHENOL A (2008)
Kuramochi, Hidetoshi, Kawamoto, Katsuya, Miyazaki, Kohei, Nagahama, Kunio, Maeda, Kouji, Li, Xian-Wei, ...
Oda, Takuzo, Watanabe, Sekiko, Nakamura, Takashi, Hidaka, Hideyuki
Viral nucleoprotein complexes were extracted from nuclei of permissive cells (CV-1) infected with simian virus 40 (SV40) and examined by electron microscopy. SV40 nucleoprotein complexes (SV40...
Takeshi Chiba Shinji, Shinji Mukohyama, Takashi Nakamura
We consider the horizon problem in a homogeneous but anisotropic universe (Bianchi type I). We show that the problem cannot be solved if (1) the matter obeys the strong energy condition with the...
Masaru Shibata, Keisuke Taniguchi, Takashi Nakamura
In this paper, we present results obtained from our recent studies on the location of the innermost stable circular orbit (ISCO) for binary neutron stars (BNSs) in several levels of post Newtonian...
Redshift Dependent Lag-Luminosity Relation in 565 BASTE Gamma Ray Bursts (2007)
Tsutsui, Ryo, Nakamura, Takashi, Yonetoku, Daisuke, Murakami, Toshio, Tanabe, Sachiko, Kodama, Yoshiki
We compared redshifts $z_Y$ from Yonetoku relation and $z_{lag}$ from the lag-luminosity relation for 565 BASTE GRBs and were surprised to find that the correlation is very low. Assuming that the...
Kakinoki, Ryosuke, Ikeguchi, Ryosuke, Nakayama, Ken, Nakamura, Takashi
Abstract Background The limited nerve sources available for the reconstruction and restoration of upper extremity function is the biggest obstacle in the treatment of brachial plexus injury (BPI). We...
Toma, Kenji, Ioka, Kunihito, Nakamura, Takashi
The late-time optical/radio afterglows of $\gamma$-ray bursts (GRBs) are believed to be synchrotron emission of electrons accelerated in relativistic collisionless shocks propagating in the ambient...
A Null Test of the Cosmological Constant (2007)
Chiba, Takeshi, Nakamura, Takashi
We provide a consistency relation between cosmological observables in general relativity with the cosmological constant. Breaking of this relation at any redshift would imply the breakdown of the...
Unstable GRB photospheres and electron-positron annihilation lines (2007)
Ioka, Kunihito, Murase, Kohta, Toma, Kenji, Nagataki, Shigehiro, Nakamura, Takashi
We propose an emission mechanism of prompt gamma-ray bursts (GRBs) that can reproduce the observed non-thermal spectra with high radiative efficiencies, >50%. Internal dissipation below a photosphere...
Functional relations and universality for several types of multiple zeta functions (2007)
名古屋大学博士学位論文 学位の種類；博士（数理学）（課程） 学位授与年月日；平成19年6月29日
Functional relations and universality for several types of multiple zeta functions (2007)
名古屋大学博士学位論文 学位の種類；博士（数理学）（課程） 学位授与年月日；平成19年6月29日
Suzuki, Mayuko, Kaya, Yuhdai, Ishida, Takahide A., Hattori, Kouhei, Miki, Kaori, Nakamura, Takashi, ...
Flowering phenology of cleistogamous annual plants Impatiens noli-tangere and Persicaria thunbergii was studied with reference to their mortality in streamside environments in northern Japan. I....
Suzuki, Mayuko, Kaya, Yuhdai, Ishida, Takahide A., Hattori, Kouhei, Miki, Kaori, Nakamura, Takashi, ...
Flowering phenology of cleistogamous annual plants Impatiens noli-tangere and Persicaria thunbergii was studied with reference to their mortality in streamside environments in northern Japan. I....
Swelling and Replicative DNA Synthesis of Detergent-treated Mouse Ascites Sarcoma Cells (2007)
Seki, Shuji, Nakamura, Takashi, Kataoka, Kazuhiro, Oda, Takuzo
Previous investigation showed that mouse ascites sarcoma cells permeabilized with appropriate concentrations of detergents (Triton X-100, Nonidet P-40 and Brij 58) had high replicative DNA synthesis...
Complete in vitro DNA replication of SV40 chromatin in digitonin-treated permeable cells. (2007)
Oda, Takuzo, Watanabe, Sekiko, Hanakawa, Shiro, Nakamura, Takashi
A permeable cell system has been developed by treatment with digitonin for studying in vitro DNA replication of chromatin. DNA replication of simian virus 40 nucleoprotein complexes (SV40 chromatin)...
Oda, Takuzo, Watanabe, Sekiko, Nakamura, Takashi
Electron microscopy of four human T-cell lines revealed the production of type C virus particles in two T-cell lines: one derived from acute lymphoblastic leukemia and the other from a leukemic...
Leonor, Isabel B., Kim, Hyun-Min, Balas, Francisco, Kawashita, Masakazu, Reis, Rui L., Kokubo, Tadashi, ...
Preparation of bioactive flexible poly(tetramethylene oxide) (PTMO)-CaO-Ta2O5 hybrids (2007)
Kamitakahara, Masanobu, Kawashita, Masakazu, Miyata, Noboru, Kokubo, Tadashi, Nakamura, Takashi
Toma, Kenji, Ioka, Kunihito, Sakamoto, Takanori, Nakamura, Takashi
The gamma-ray burst (GRB) 060218 has ~ 10^5 times lower luminosity than typical long GRBs, and is associated with a supernova (SN). The radio afterglow displays no jet break, so that this burst might...
Alam, Shahjalal S., Nakamura, Takashi, Naganuma, Atsushi, Nozaki, Akito, Nouso, Kazuhiro, Shimomura, Hiroyuki, ...
We have shown that highly proofreading DNA polymerase is required for the polymerase chain reaction in the genetic analysis of hepatitis C virus (HCV). To clarify the status of HCV quasispecies in...
Nozaki, Akito, Naganuma, Atsushi, Nakamura, Takashi, Tanaka, Katsuaki, Sekihara, Hisahiko, Kato, Nobuyuki
We have developed a reliable internally controlled RT-nested PCR method for the detection of hepatitis C virus (HCV) RNA using in vitro synthesized Renilla luciferase (Rluc) RNA as an internal...
High Energy Neutrinos and Cosmic-Rays from Low-Luminosity Gamma-Ray Bursts? (2006)
Murase, Kohta, Ioka, Kunihito, Nagataki, Shigehiro, Nakamura, Takashi
The recently discovered gamma-ray burst (GRB) GRB 060218/SN 2006aj is classified as an X-ray Flash with very long duration driven possibly by a neutron star. Since GRB 060218 is very near about 140...
Photodegradation of PEEK sheets under tensile stress (2006)
Nakamura, Hiroshi, Nakamura, Takashi, Noguchi, Toru, Imagawa, Kichiro
The photochemical reaction of poly(ether ether ketone) (PEEK) sheets under tensile loads has been investigated. Two types of UV irradiation tests were carried out in a vacuum environment: with and...
Photodegradation of PEEK sheets under tensile stress (2006)
Nakamura, Hiroshi, Nakamura, Takashi, Noguchi, Toru, Imagawa, Kichiro
The photochemical reaction of poly(ether ether ketone) (PEEK) sheets under tensile loads has been investigated. Two types of UV irradiation tests were carried out in a vacuum environment: with and...
Photodegradation of PEEK sheets under tensile stress (2006)
Nakamura, Hiroshi, Nakamura, Takashi, Noguchi, Toru, Imagawa, Kichiro, 中村, 孝
The photochemical reaction of poly(ether ether ketone) (PEEK) sheets under tensile loads has been investigated. Two types of UV irradiation tests were carried out in a vacuum environment: with and...
Ioka, Kunihito, Toma, Kenji, Yamazaki, Ryo, Nakamura, Takashi
Most X-ray afterglows of gamma-ray bursts (GRBs) observed by the Swift satellite have a shallow decay phase t^{-1/2} in the first few hours. This is not predicted by the standard afterglow model and...
Shallow Decay of Early X-ray Afterglows from Inhomogeneous Gamma-Ray Burst Jets (2005)
Toma, Kenji, Ioka, Kunihito, Yamazaki, Ryo, Nakamura, Takashi
Almost all the X-ray afterglows of gamma-ray bursts (GRBs) observed by the Swift satellite have a shallow decay phase in the first thousands of seconds. We show that in an inhomogeneous jet...
Tail Emission of Prompt Gamma-Ray Burst Jets (2005)
Yamazaki, Ryo, Toma, Kenji, Ioka, Kunihito, Nakamura, Takashi
Tail emission of the prompt gamma-ray burst (GRB) is discussed using a multiple emitting sub-shell (inhomogeneous jet, sub-jets or mini-jets) model, where the whole GRB jet consists of many emitting...
7th International Conference on Accelerator Applications 2005 (2005)
Carsughi, Flavio, Nakamura, Takashi, Filger, Detlef, Goldenbaum, Frank
Ep-Eiso Correlation in a Multiple Subjet Model of Gamma-Ray Bursts (2005)
Toma, Kenji, Yamazaki, Ryo, Nakamura, Takashi
We perform Monte Carlo simulations to study Ep-Eiso correlation in the context of a multiple subjet model (or inhomogeneous jet model) for gamma-ray bursts (GRBs), X-ray--rich GRBs (XRRs), and X-ray...
Yonetoku, Daisuke, Yamazaki, Ryo, Nakamura, Takashi, Murakami, Toshio
We propose a method to estimate the pseudo jet opening half-angle of GRBs using the spectral peak energy ($\Ep$)--peak luminosity relation (so called Yonetoku relation) as well as the...
A Unified Model for Gamma-Ray Bursts (2005)
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi, Toma, Kenji
A possible unified model of short and long gamma-ray bursts (GRBs), X-ray rich GRBs, and X-ray flashes is proposed. It is assumed that the jet of a GRB consists of many emitting sub-shells (i.e., an...
Bernoulli numbers and multiple zeta values (2005)
We show an apparently new expression of Bernoulli numbers, simultaneously we give an expression of multiple zeta values $\zeta(2m, 2m, \dots, 2m)$.
Neutron Spectra from Intermediate-Energy Nucleus-Nucleus Reactions (2005)
Iwase, Hiroshi, Iwata, Yoshiyuki, Nakamura, Takashi, Gudima, Konstantin, Mashnik, Stepan, Sierk, Arnold, ...
Double-differential cross sections of neutron production at angles from 0 to 110 degrees from many reactions induced by light and medium nuclei on targets from 12-C to 208-Pb, at several incident...
Oishi, Koji, Nakao, Noriaki, Kosako, Kazuaki, Yamakawa, Hiroshi, Nakashima, Hiroshi, Kawai, Masayoshi, ...
Precise estimation of induced activities in concrete shields for high-energy accelerator facilities is one of the most important issues that need to be solved, not only for the reduction of exposure...
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi, Toma, Kenji
We propose a possible unified model of short and long gamma-ray bursts (GRBs), X-ray rich GRBs, and X-ray flashes. The jet of a GRB is assumed to consist of multiple sub-jets or sub-shells (i.e., an...
Kuroki, Hiroshi, Nakagawa, Yasuaki, Mori, Koji, Ohba, Mao, Suzuki, Takashi, Mizuno, Yasuyuki, ...
Abstract We investigated quantitative changes over time in ultrasound signal intensity (an index of stiffness), signal duration (an index of surface irregularity), and interval between signals (an...
Takahashi, Ryuichi, Nakamura, Takashi
We show that ten(one) years operation of the ultimate DECIGO (DECihertz Interferometer Gravitational wave Observatory) can determine the cosmic equation of the state with such accuracy that...
A Possible Origin of Bimodal Distribution of Gamma-Ray Bursts (2004)
Toma, Kenji, Yamazaki, Ryo, Nakamura, Takashi
We study the distribution of the durations of gamma-ray bursts (GRBs) in the unified model of short and long GRBs recently proposed by Yamazaki, Ioka, and Nakamura. Monte Carlo simulations show clear...
Gravitational Wave Memory of Gamma-Ray Burst Jets (2004)
Sago, Norichika, Ioka, Kunihito, Nakamura, Takashi, Yamazaki, Ryo
Gamma-Ray Bursts (GRBs) are now considered as relativistic jets. We analyze the gravitational waves from the acceleration stage of the GRB jets. We show that (i) the point mass approximation is not...
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi
Taking into account the recent suggestion that a short gamma-ray burst (GRB) looks like the first 1 sec of a long GRB, we propose that the jet of a GRB consists of multiple sub-jets or sub-shells...
Peak Energy-Isotropic Energy Relation in the Off-Axis Gamma-Ray Burst Model (2004)
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi
Using a simple uniform jet model of prompt emissions of gamma-ray bursts (GRBs), we reproduce the observed peak energy--isotropic energy relation. A Monte Carlo simulation shows that the...
Takahashi, Shunichi, Nakamura, Takashi, Sakamizu, Manabu, Woesik, Robert Van, Yamasaki, Hideo
In a coral-algae symbiotic system, heat-dependent photoinhibition of photosystem II (PSII) leads to coral bleaching. When the reef-building coral Acropora digitifera was exposed to light, a moderate...
Measured proton sensitivities of bubble detectors (2004)
Takada, Masashi, Kitamura, Hisashi, Koi, Tatsumi, Nakamura, Takashi, Fujitaka, Kazunobu
The neutron dose equivalent in aircraft is measured using commercial bubble detectors, but at high altitudes there are not only neutrons but also protons. Bubble detectors have been used because they...
MEASURED PROTON SENSITIVITIES OF BUBBLE DETECTORS (2004)
Takada, Masashi, Kitamura, Hisashi, Koi, Tatsumi, Nakamura, Takashi, Fujitkata, Kazunobu
The neutron dose equivalent in aircraft is measured using commercial bubble detectors, but at high altitudes there are not only neutrons but also protons. Bubble detectors have been used because they...
Interactions between Sox9 and {beta}-catenin control chondrocyte differentiation (2004)
Akiyama, Haruhiko, Lyons, Jon P., Mori-Akiyama, Yuko, Yang, Xiaohong, Zhang, Ren, Zhang, Zhaoping, ...
Chondrogenesis is a multistep process that is essential for endochondral bone formation. Previous results have indicated a role for β-catenin and Wnt signaling in this pathway. Here we show the...
MEASURED PROTON SENSITIVITIES OF BUBBLE DETECTORS (2004)
Takada, Masashi, Kitamura, Hisashi, Koi, Tatsumi, Nakamura, Takashi, Fujitkata, Kazunobu
The neutron dose equivalent in aircraft is measured using commercial bubble detectors, but at high altitudes there are not only neutrons but also protons. Bubble detectors have been used because they...
Cosmological X-Ray Flashes from Off-Axis Jets (2003)
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi
The of the cosmological X-ray flashes detected by WFC/BeppoSAX is calculated theoretically in a simple jet model. The total emission energy from the jet is assumed to be constant. We find that if...
GRB980425 in the Off-Axis Jet Model of the Standard GRBs (2003)
Yamazaki, Ryo, Yonetoku, Daisuke, Nakamura, Takashi
Using a simple off-axis jet model of GRBs, we can reproduce the observed unusual properties of the prompt emission of GRB980425, such as the extremely low isotropic equivalent gamma-ray energy, the...
Near-Infrared Colors of Gamma-Ray Burst Afterglows and Cosmic Reionization History (2003)
Inoue, Akio K., Yamazaki, Ryo, Nakamura, Takashi
Using the near-infrared (NIR) observations of the afterglows of the high redshift ($5 \la z \la 25$) gamma-ray bursts (GRBs) which will be detected by the {\it Swift} satellite, we discuss a way to...
Takahashi, Ryuichi, Nakamura, Takashi
It may be possible to construct a laser interferometer gravitational wave antenna in space with $h_{rms}\sim 10^{-23}$ at $ f\sim 0.1{\rm Hz}$ in $\sim 2020$. This deci hertz antenna may be called...
An Off-Axis Jet Model For GRB980425 and Low Energy Gamma-Ray Bursts (2003)
Yamazaki, Ryo, Yonetoku, Daisuke, Nakamura, Takashi
Using a simple off-axis jet model of GRBs, we can reproduce the observed unusual properties of the prompt emission of GRB980425, such as the extremely low isotropic equivalent gamma-ray energy, the...
Kawamura, Mari, Oohara, Ken-ichi, Nakamura, Takashi
We are developing 3 dimensional simulation codes for coalescing binary neutron stars. A code using the maximal slicing condition is obtained. To evaluate the gravitational radiation, we implemented a...
Wave Effects in Gravitational Lensing of Gravitational Waves from Chirping Binaries (2003)
Takahashi, Ryuichi, Nakamura, Takashi
In the gravitational lensing of gravitational waves, the wave optics should be used instead of the geometrical optics when the wavelength $\lambda$ of the gravitational waves is longer than the...
Small localized black holes in a braneworld: Formulation and numerical method (2003)
Kudoh, Hideaki, Tanaka, Takahiro, Nakamura, Takashi
No realistic black holes localized on a 3-brane in the Randall-Sundrum infinite braneworld have been found so far. The problem of finding a static black hole solution is reduced to a boundary value...
Cosmological X-ray Flashes in the Off-Axis Jet Model (2002)
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi
The of the cosmological X-ray flashes detected by Wide Field Cameras on BeppoSAX is calculted theoretically in a simple jet model. The total emission energy from the jet is assumed to be constant....
Delayed Flashes from Counter Jets of Gamma Ray Bursts (2002)
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi
If X-ray flashes are due to the forward jet emissions from gamma ray bursts (GRBs) observed with large viewing angles, we show that a prompt emission from a counter jet should be observed as a...
Possible Formation Scenario of the Quark Star of Maximum Mass around 0.7 solar mass (2002)
If there exists the quark star of maximum mass $\sim 0.7\sol$ as suggested by recent Chandra observations, we show that the general relativistic collapse of a neutron star of mass greater than the...
Neutron Production Measurements Relevant to Shielding for Space-Related Activities (2002)
Heilbronn, Lawrence, Iwata, Yoshiyuki, Murakami, Takeshi, Iwase, Hiroshi, Nakamura, Takashi, Sato, Hisaki, ...
Neutron production cross sections have been measured from 290 MeV/nucleon C and 600 MeV/nucleon Ne interacting in a slab of simulated Martian regolith/polyethylene composite, and from 400 MeV/nucleon...
X-ray Flashes from Off-axis Gamma-Ray Bursts (2002)
Yamazaki, Ryo, Ioka, Kunihito, Nakamura, Takashi
Ioka and Nakamura (2001) proposed a simple jet model that is compatible with the peak luminosity-spectral lag relation, the peak luminosity-variability relation and various other relations in the...
Possible Origin of Lognormal Distributions in Gamma-Ray Bursts (2002)
Ioka, Kunihito, Nakamura, Takashi
We show that if the intrinsic break energy of Gamma-Ray Bursts (GRBs) is determined by the product of more than three random variables the observed break energy distribution becomes almost lognormal...
Demonstration of Oblique Detonation Wave for Hypersonic Propulsion (2002)
Nakamura, Takashi, Schuh, Michael J., Randall, Donald S., Dahm, Thomas J., Pratt, David T.
The Oblique Detonation Wave Engine (ODWE) offers a number of advantages over the Supersonic Combustor Ramjet (SCRAMJET) for hypersonic aeropropulsion. The objective of this program is to obtain data...
Suzuki, Noriyuki, Yu, Jian, Shioda, Nobuyuki, Asami, Hayato, Nakamura, Takashi, Huhn, Thomas, ...
A novel methodology was developed for the preparation of isospecific metallocene catalysts for olefin polymerization that are tethered on silica surfaces with covalent bonds. A racemic...
Bactericidal activity of phlorotannins from the brown alga Ecklonia kurome (2002)
Nagayama, Koki, Iwamura, Yoshitoshi, Shibata, Toshiyuki, Hirayama, Izumi, Nakamura, Takashi
The bactericidal activity of phlorotannins from brown algae against food-borne pathogenic bacteria (25 strains), methicillin-resistant Staphylococcus aureus (MRSA) (nine strains) and Streptococcus...
Bactericidal activity of phlorotannins from the brown alga Ecklonia kurome (2002)
Nagayama, Koki, Iwamura, Yoshitoshi, Shibata, Toshiyuki, Hirayama, Izumi, Nakamura, Takashi
The bactericidal activity of phlorotannins from brown algae against food-borne pathogenic bacteria (25 strains), methicillin-resistant Staphylococcus aureus (MRSA) (nine strains) and Streptococcus...
Bactericidal activity of phlorotannins from the brown alga Ecklonia kurome (2002)
Nagayama, Koki, Iwamura, Yoshitoshi, Shibata, Toshiyuki, Hirayama, Izumi, Nakamura, Takashi
The bactericidal activity of phlorotannins from brown algae against food-borne pathogenic bacteria (25 strains), methicillin-resistant Staphylococcus aureus (MRSA) (nine strains) and Streptococcus...
Is dark energy the only solution to the apparent acceleration of the present universe? (2001)
Iguchi, Hideo, Nakamura, Takashi, Nakao, Ken-ichi
Even for the observed luminosity distance D_L(z), which suggests the existence of dark energy, we show that an inhomogeneous dust universe solution without dark energy is possible in general. Future...
Oscillating scalar-field dark matter in supergravity (2001)
Seto, Osamu, Kohri, K., Nakamura, Takashi
We show that an oscillating scalar field in supergravity of mass of the order of $\sim$ TeV with a nonzero vacuum expectation value ($\sim 10^{10}$ GeV) can be a candidate of cold dark matter (CDM)....
Seto, Naoki, Kawamura, Seiji, Nakamura, Takashi
It may be possible to construct a laser interferometer gravitational wave antenna in space with $h_{rms}\sim 10^{-27}$ at $ f\sim 0.1{\rm Hz}$ in this century. We show possible specification of this...
Ioka, Kunihito, Nakamura, Takashi
We compute the kinematical dependence of the peak luminosity, the pulse width and the spectral lag of the peak luminosity on the viewing angle $\theta_v$ of a jet. For appropriate model parameters we...
Saijo, Motoyuki, Nakamura, Takashi
We compute the spectrum and the waveform of gravitational waves generated by the inspiral of a disk or a spherical like dust body into a Kerr black hole. We investigate the effect of the radius R of...
Microlensing of collimated Gamma-Ray Burst afterglows (2001)
Ioka, Kunihito, Nakamura, Takashi
We investigate stellar microlensing of the collimated gamma-ray burst afterglows. A spherical afterglow appears on the sky as a superluminally expanding thin ring (``ring-like'' image), which is...
Real-coded adaptive range genetic algorithm applied to transonic wing optimization (2001)
Akira Oyama, Shigeru Obayashi, Takashi Nakamura
applied to a practical three-dimensional shape optimization for aerodynamic design of an aircraft wing. The real-coded ARGAs possess both advantages of the binary-coded ARGAs and the floating-point...
Real-coded adaptive range genetic algorithm applied to transonic wing optimization (2001)
Akira Oyama, Shigeru Obayashi, Takashi Nakamura
applied to a practical three-dimensional shape optimization for aerodynamic design of an aircraft wing. The real-coded ARGAs possess both advantages of the binary-coded ARGAs and the floating-point...
Saijo, Motoyuki, Nakamura, Takashi
We compute the spectrum and the waveform of gravitational waves generated by the inspiral of a disk or a spherical like dust body into a Kerr black hole. We investigate the effect of the radius R of...
Determining the Equation of State of the Expanding Universe Using a New Independent Variable (2000)
Nakamura, Takashi, Chiba, Takeshi
To determine the equation of state of the universe, we propose to use a new independent variable $R\equiv (H_0/c)(d_L(z)/(1+z))$, where $H_0$ and $d_L(z)$ are the present Hubble parameter and the...
Saijo, Motoyuki, Nakamura, Takashi
We computed the spectrum of gravitational waves from a dust disk star of radius R inspiraling into a Kerr black hole of mass M and specific angular momentum a. We found that when R is much larger...
Feasibility of Reconstructing the Quintessential Potential Using SNIa Data (2000)
Chiba, Takeshi, Nakamura, Takashi
We investigate the feasibility of the method for reconstructing the equation of state and the effective potential of the quintessence field from SNIa data. We introduce a useful functional form to...
Response of Interferometric Detectors to Scalar Gravitational Waves (2000)
Nakao, Ken-ichi, Harada, Tomohiro, Shibata, Masaru, Kawamura, Seiji, Nakamura, Takashi
We rigorously analyze the frequency response functions and antenna sensitivity patterns of three types of interferometric detectors to scalar mode of gravitational waves which is predicted to exist...
We assume that internal shocks of Gamma Ray Bursts (GRBs) consist of multiple sub-jets with a collimation half-angle $\sim {\rm several }\times\gamma_i^{-1}$, where $\gamma_i$ is the Lorenz factor of...
Taniguchi, Keisuke, Nakamura, Takashi
Solutions to equilibrium sequences of irrotational binary polytropic stars in Newtonian gravity are expanded in a power of $\epsilon=a_0/R$, where R and $a_0$ are the orbital separation of the binary...
3D General Relativistic Simulations of Coalescing Binary Neutron Stars (1999)
Oohara, Ken-ichi, Nakamura, Takashi
We develop a 3 dimensional computer code to study a coalescing neutron star binary. The code can currently follow the evolution up to two stars begin to merge from two spherical stars of mass 1 solar...
Taniguchi, Keisuke, Nakamura, Takashi
A solution to an equilibrium of irrotational binary polytropic stars in Newtonian gravity is expanded in a power of \epsilon=a_0/R, where R and a_0 are the separation of the binary system and the...
A formula for off-axis emissions from the beamed afterglow of GRBs in a synchrotron model is derived. The formula is applied to an inhomogeneous circumstellar matter obeying n proportional to 1/r**2...
Ioka, Kunihito, Tanaka, Takahiro, Nakamura, Takashi
Under the assumption that the Milky Way's dark halo consists of primordial black hole MACHOs (PBHMACHOs), the mass density of the halo can be measured by the low frequency gravitational waves...
Suzuki, Noriyuki, Asami, Hayato, Nakamura, Takashi, Huhn, Thomas, Fukuoka, Atsushi, Ichikawa, Masaru, ...
Nakamura, Takashi, Nakatani, Kazuhiko, Saito, Isao
Of the non-covalent binding forces in DNA-drug or DNA-protein interaction, electrostatic interaction, stacking interaction, hydrogen bonds and hydrophobic effect have been well established. However,...
A Way to 3D Numerical Relativity --- Coalescing Binary Neutron Stars --- (1998)
Nakamura, Takashi, Oohara, Ken-ichi
One of the most promising sources of gravitational radiation is coalescence of binary neutron stars or black holes. In order to study gravitational radiation at the merging phase of coalescing binary...
Determining the Equation of State of the Expanding Universe: Inverse Problem in Cosmology (1998)
Nakamura, Takashi, Chiba, Takeshi
Even if the luminosity distance as a function of redshift is obtained accurately using, for example, Type Ia supernovae, the equation of state of the Universe cannot be determined uniquely but...
Research on New Concepts in Energy Conversion. (1998)
Oliver, David A., Nakamura, Takashi
This document presents a summary on the research of the feasibility of Rankine-cycle power systems incorporating nonequilibrium MHD generators. Briefly discussed are the results of recent research...
Solar Thermal Propulsion for Small Spacecraft - Engineering System Development and Evaluation (1998)
Nakamura, Takashi, Krech, Robert H., McClanahan, James A., Shoji, James M., Partch, Russell, Quinn, Skylar
This paper discusses results of a program to develop an innovative solar thermal propulsion system for application to orbit change and mobility for small spacecraft. In this system, solar radiation...
Nakamura, Takashi, Kishima, Kohichiro, Jinbo, Katsuhisa, Matsuo, Yohtaro, Nagai, Fumio
This paper concerned metals in some important way and contained information about, utilized, or discussed these subjects: basic topics: experimental materials and material types: fe-4c-2si , ductile...
Low frequency gravitational waves from black hole MACHO binaries (1998)
Ioka, Kunihito, Tanaka, Takahiro, Nakamura, Takashi
The intensity of low frequency gravitational waves from black hole MACHO binaries is studied. First we estimate the gravitational wave background produced by black hole MACHO binaries in the Milky...
The Luminosity Distance, the Equation of State, and the Geometry of the Universe (1998)
Chiba, Takeshi, Nakamura, Takashi
The second derivative of the luminosity distance with respect to the redshift is written in terms of the deceleration parameter $q_0$. We point out that the third derivative contains the information...
A Model for Non High Energy Gamma Ray Bursts and Sources of Ultra High Energy Cosmic Rays (1998)
As a progenitor of NHE (Non High Energy) GRBs, we propose a (C+O) star and a neutron star (black hole) close binary system. Since the (C+O) star is tidally locked, a new born pulsar should be a milli...
Ioka, Kunihito, Chiba, Takeshi, Tanaka, Takahiro, Nakamura, Takashi
We study black hole MACHO binary formation through three-body interactions in the early universe at $t\sim 10^{-5}$s. The probability distribution functions of the eccentricity and the semimajor axis...
Observational tests of x-matter models (1998)
Chiba, Takeshi, Sugiyama, Naoshi, Nakamura, Takashi
We study gravitational lensing statistics, matter power spectra and the angular power spectra of the cosmic microwave background (CMB) radiation in x-matter models. We adopt an equation-of-state of...
Expected EAGLE event rate towards the Magellanic Clouds (1998)
Nakamura, Takashi, Nishi, Ryoichi
We propose to search for MACHOs by observing EAGLE (Extremely Amplified Gravitational LEnsing) events of a majority of dim stars. This search is independent of the usual one. For the detection limit...
Shibata, Masaru, Taniguchi, Keisuke, Nakamura, Takashi
In this paper, we present results obtained from our recent studies on the location of the innermost stable circular orbit (ISCO) for binary neutron stars (BNSs) in several levels of post Newtonian...
Shibata, Masaru, Oohara, Ken-ichi, Nakamura, Takashi
We present numerical results on the hydrodynamic stability of coalescing binary stars in the first post Newtonian(1PN) approximation of general relativity. We pay particular attention to the...
Gravitational Waves from Coalescing Black Hole MACHO Binaries (1997)
Nakamura, Takashi, Sasaki, Misao, Tanaka, Takahiro, Thorne, Kip S.
If MACHOs are black holes of mass about 0.5 solar mass, they must have been formed in the early universe when the temperature was about 1 GeV. We estimate that in this case in our galaxy's halo out...
Chiba, Takeshi, Mukohyama, Shinji, Nakamura, Takashi
We consider the horizon problem in a homogeneous but anisotropic universe (Bianchi type I). We show that the problem cannot be solved if (1) the matter obeys the strong energy condition with the...
Cosmology with x-matter (1997)
Chiba, Takeshi, Sugiyama, Naoshi, Nakamura, Takashi
Motivated by the possibility of $H_0t_0 > 1$ where $H_0$ and $t_0$ are the Hubble parameter and the age of the universe, respectively, we investigate the cosmology including x-matter. x-matter is...
Alternate pages blank. Facsimile of the author's original dissertation. Includes bibliographical references.
The Minimum Mass of the First Stars and the Anthropic Principle (1996)
Nakamura, Takashi, Uehara, Hideya, Chiba, Takeshi
The lower limit of the mass of the first stars suggested recently may imply the formation of massive stars of mass greater than 8 solar mass irrespective of the details of the initial mass function....
Harada, Tomohiro, Chiba, Takeshi, Nakao, Ken-ichi, Nakamura, Takashi
Unlike general relativity, scalar-tensor theories of gravity predict scalar gravitational waves even from a spherically symmetric gravitational collapse. We solve numerically the generation and...
Fragmentation of the Primordial Gas Clouds and the Lower Limit on the Mass of the First Stars (1996)
Uehara, Hideya, Susa, Hajime, Nishi, Ryoichi, Yamada, Masako, Nakamura, Takashi
We discuss the fragmentation of primordial gas clouds in the universe after decoupling. Comparing the time scale of collapse with that of fragmentation, we obtain the typical mass of a fragment both...
Taniguchi, Keisuke, Nakamura, Takashi
The innermost stable circular orbits (ISCO) of coalescing neutron star-black hole binary are studied taking into account both the tidal and relativistic effects. We adopt the generalized...
Koshikawa, Naohiko, Nakamura, Takashi, Tsuchiya, Naoto, Isaji, Mitsuko, Yasumitsu, Hidetaro, Umeda, Makoto, ...
Our previous studies have shown that some human cancer cell lines produce pancreatic trypsinogen, plasminogen, and tissue-type kallikrein. To understand the regulatory mechanism of these proteinases,...
Volume Expansion Rate and The Age of The Universe (1995)
Nakamura, Takashi, Nakao, Ken-ichi, Chiba, Takeshi, Shiromizu, Tetsuya
Under four assumptions such that 1) Einstein's theory of gravity is correct, 2) existence of foliation by geodesic slicing, 3) the trace of the extrinsic curvature, $K$, is negative at the present...
The Microlensing and Halo Models of the Galaxy (1995)
Kan-ya, Yukitoshi, Nishi, Ryoichi, Nakamura, Takashi
We investigated the dependence of the optical depth $\tau$ of the microlensing events on model parameters of the Galactic halo. We only consider Galactic mass models in which the rotation curve...
Hubble Parameter in Void Universe (1995)
Nakao, Ken-ichi, Gouda, Naoteru, Chiba, Takeshi, Ikeuchi, Satoru, Nakamura, Takashi, Shibata, Masaru
We investigate the distance-redshift relation in the simple void model. As discussed by Moffat and Tatarski, if the observer stays at the center of the void, the observed Hubble parameter is not so...
Stress analysis of chemically leavened biscuits: Application of pseudoelastic, bi-layer model (1995)
The purpose of this research focus was to develop a procedure for predicting the stress state in a cracker during a simultaneous heat/mass transfer process. The stress analysis incorporated a...
International pleasure travel : inter-cultural interaction and attitude change (1995)
Facsimile of the author's original dissertation. Alternate pages blank. Includes bibliographical references (leaves 89-92)
Technological rules and constraints affecting design of precast concrete housing (1994)
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1994.
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1994.
Technological rules and constraints affecting design of precast concrete housing (1994)
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1994.
Analysis of Taylor vortices in the rotating couette system / (1993)
Typescript (photocopy).
Printout.
Nakamura, Takashi, Matsumuro, Akiyoshi, Kuribayashi, Toshiro, Matsubara, Kinya, Shima, Masami, Shimoo, Kazutoshi, ...
Objective: The aim was to validate echocardiographic assessment of acute changes of left ventricular stroke volume in normal rats. Methods: By transthoracic use of a 7.5 MHz ultrasonic transducer,...
4th Workshop on Elementary-particle of the universe (1991)
Hikasa, Ken Ichi, Nakamura, Takashi, Ohshima, Takayoshi, Suzuki, Atsuto
Apatite- and Wollastonite-Containg Glass-Ceramics for Prosthetic Application (1982)
Kokubo, Tadashi, Shigematsu, Masazumi, Nagashima, Yukihito, Tashiro, Megumi, Nakamura, Takashi, Yamamuro, Takao, ...
POLARIZATION OF RARE GAS ATOMS IN THE VICINITY OF SURFACES OF ALKALI HALIDE CRYSTALS (1982)
HIGASHI, Kazuko, TATEWAKI, Hiroshi, NAKAMURA, Takashi
Note
POLARIZATION OF RARE GAS ATOMS IN THE VICINITY OF SURFACES OF ALKALI HALIDE CRYSTALS (1982)
HIGASHI, Kazuko, TATEWAKI, Hiroshi, NAKAMURA, Takashi
Note
ODA, Takuzo, NAKAMURA, Takashi, WATANABE, Sekiko
Transcription complexes of nonribosomal chromatin in primary spermatocyte nuclei of Drosophila melanogaster were studied under the electron microscope. Microcentrifugation techniques allowed direct...
Electron Microscopy of the Replicative Form DNA of Coliphage fd (1971)
ODA, Takuzo, NAKAMURA, Takashi, WATANABE, Sekiko, TAKANAMI, Mituru
Electron microscopic observations were made on the replicative form DNA of bacteriophage fd. The doubly closed replicative form DNA (RF-1 DNA) was purified from E. coli cells infected with fd, and...
Supervised by Jack L. Kerrebrock.
Experimental study of a single confined vortex flow. (1966)
Massachusetts Institute of Technology. Dept. of Aeronautics and Astronautics. Thesis. 1966. M.S.
An analysis of a part of a continuous concrete bridge /--by Takashi Nakamura. (1949)
Thesis (B.S.)--Michigan State College of Agriculture and Applied Science, 1949.
Mishima, Michiaki, Hirai, Toyohiro, Itoh, Harumi, Nakano, Yasutaka, Sakai, Hiroaki, Muro, Shigeo, ...
Increases in the low attenuation areas (LAA) of chest x-ray computed tomography images in patients with chronic obstructive pulmonary disease (COPD) have been reported to reflect the development of...
Yamaguchi, Masahiro, Nakamoto, Mika, Honda, Hiroaki, Nakagawa, Toshiyuki, Fujita, Hiroshi, Nakamura, Takashi, ...
Skeletal formation is a fundamental element of body patterning and is strictly regulated both temporally and spatially by a variety of molecules. Among these, retinoic acid (RA) has been shown to be...
Terashi, Kenji, Oka, Mikio, Soda, Hiroshi, Fukuda, Minoru, Kawabata, Shigeru, Nakatomi, Katsumi, ...
To investigate interactions between the multidrug resistance protein (MRP) and antimicrobial agents, we examined the effects of 12 agents on vincristine sensitivity and efflux of the calcein...
Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation
Yoshida, Keiji, Oida, Hiroji, Kobayashi, Takuya, Maruyama, Takayuki, Tanaka, Masaharu, Katayama, Teruaki, ...
Bone remodeling, comprising resorption of existing bone and de novo bone formation, is required for the maintenance of a constant bone mass. Prostaglandin (PG)E2 promotes both bone resorption and...
Sueyoshi, Noriyuki, Kita, Katsuhiro, Okino, Nozomu, Sakaguchi, Keishi, Nakamura, Takashi, Ito, Makoto
We report here the molecular cloning and expression of a hemolytic sphingomyelinase from an aquatic bacterium, Pseudomonas sp. strain TK4. The sphingomyelinase gene was found to consist of 1,548...
Chondromodulin I Is a Bone Remodeling Factor
Nakamichi, Yuko, Shukunami, Chisa, Yamada, Takashi, Aihara, Ken-ichi, Kawano, Hirotaka, Sato, Takashi, ...
Chondromodulin I (ChM-I) was supposed from its limited expression in cartilage and its functions in cultured chondrocytes as a major regulator in cartilage development. Here, we generated mice...
Suppressive function of androgen receptor in bone resorption
Kawano, Hirotaka, Sato, Takashi, Yamada, Takashi, Matsumoto, Takahiro, Sekine, Keisuke, Watanabe, Tomoyuki, ...
As locally converted estrogen from testicular testosterone contributes to apparent androgen activity, the physiological significance of androgen receptor (AR) function in the beneficial effects of...
Brain masculinization requires androgen receptor function
Sato, Takashi, Matsumoto, Takahiro, Kawano, Hirotaka, Watanabe, Tomoyuki, Uematsu, Yoshikatsu, Sekine, Keisuke, ...
Testicular testosterone produced during a critical perinatal period is thought to masculinize and defeminize the male brain from the inherent feminization program and induce male-typical behaviors in...
Hata, Hiroshi, Sakaguchi, Noriko, Yoshitomi, Hiroyuki, Iwakura, Yoichiroh, Sekikawa, Kenji, Azuma, Yoshiaki, ...
Cytokines play key roles in spontaneous CD4+ T cell–mediated chronic autoimmune arthritis in SKG mice, a new model of rheumatoid arthritis. Genetic deficiency in IL-6 completely suppressed the...
Kuroki, Hiroshi, Nakagawa, Yasuaki, Mori, Koji, Ohba, Mao, Suzuki, Takashi, Mizuno, Yasuyuki, ...
We investigated quantitative changes over time in ultrasound signal intensity (an index of stiffness), signal duration (an index of surface irregularity), and interval between signals (an index of...
Kiyohara, Masashi, Sakaguchi, Keishi, Yamaguchi, Kuniko, Araki, Toshiyoshi, Nakamura, Takashi, Ito, Makoto
We cloned a novel β-1,3-xylanase gene, consisting of a 1728-bp open reading frame encoding 576 amino acid residues, from a marine bacterium, Vibrio sp. strain AX-4. Sequence analysis revealed that...
Kita, Katsuhiro, Sueyoshi, Noriyuki, Okino, Nozomu, Inagaki, Masanori, Ishida, Hideharu, Kiso, Makoto, ...
We have reported previously that the ceramidase from Pseudomonas aeruginosa AN17 isolated from a patient with atopic dermatitis requires detergents for hydrolysis of ceramide (Cer) [Okino, Tani,...
Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy
Ito, Hiromu, Koefoed, Mette, Tiyapatanaputi, Prarop, Gromov, Kirill, Goater, J Jeffrey, Carmouche, Jonathan, ...
Structural allograft healing is limited because of a lack of vascularization and remodeling. To study this we developed a mouse model that recapitulates the clinical aspects of live autograft and...
Interactions between Sox9 and β-catenin control chondrocyte differentiation
Akiyama, Haruhiko, Lyons, Jon P., Mori-Akiyama, Yuko, Yang, Xiaohong, Zhang, Ren, Zhang, Zhaoping, ...
Chondrogenesis is a multistep process that is essential for endochondral bone formation. Previous results have indicated a role for β-catenin and Wnt signaling in this pathway. Here we show the...
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors
Akiyama‡, Haruhiko, Kim‡, Jung-Eun, Nakashima, Kazuhisa, Balmes, Gener, Iwai, Naomi, Deng, Jian Min, ...
The transcription factor Sox9 is expressed in all chondroprogenitors and has an essential role in chondrogenesis. Sox9 is also expressed in other tissues, including central nervous system, neural...
Premature ovarian failure in androgen receptor-deficient mice
Shiina, Hiroko, Matsumoto, Takahiro, Sato, Takashi, Igarashi, Katsuhide, Miyamoto, Junko, Takemasa, Sayuri, ...
Premature ovarian failure (POF) syndrome, an early decline of ovarian function in women, is frequently associated with X chromosome abnormalities ranging from various Xq deletions to complete loss of...
Mishima, Michiaki, Hirai, Toyohiro, Itoh, Harumi, Nakano, Yasutaka, Sakai, Hiroaki, Muro, Shigeo, ...
Increases in the low attenuation areas (LAA) of chest x-ray computed tomography images in patients with chronic obstructive pulmonary disease (COPD) have been reported to reflect the development of...
Yamaguchi, Masahiro, Nakamoto, Mika, Honda, Hiroaki, Nakagawa, Toshiyuki, Fujita, Hiroshi, Nakamura, Takashi, ...
Skeletal formation is a fundamental element of body patterning and is strictly regulated both temporally and spatially by a variety of molecules. Among these, retinoic acid (RA) has been shown to be...
Terashi, Kenji, Oka, Mikio, Soda, Hiroshi, Fukuda, Minoru, Kawabata, Shigeru, Nakatomi, Katsumi, ...
To investigate interactions between the multidrug resistance protein (MRP) and antimicrobial agents, we examined the effects of 12 agents on vincristine sensitivity and efflux of the calcein...
Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation
Yoshida, Keiji, Oida, Hiroji, Kobayashi, Takuya, Maruyama, Takayuki, Tanaka, Masaharu, Katayama, Teruaki, ...
Bone remodeling, comprising resorption of existing bone and de novo bone formation, is required for the maintenance of a constant bone mass. Prostaglandin (PG)E2 promotes both bone resorption and...
Sueyoshi, Noriyuki, Kita, Katsuhiro, Okino, Nozomu, Sakaguchi, Keishi, Nakamura, Takashi, Ito, Makoto
We report here the molecular cloning and expression of a hemolytic sphingomyelinase from an aquatic bacterium, Pseudomonas sp. strain TK4. The sphingomyelinase gene was found to consist of 1,548...
Chondromodulin I Is a Bone Remodeling Factor
Nakamichi, Yuko, Shukunami, Chisa, Yamada, Takashi, Aihara, Ken-ichi, Kawano, Hirotaka, Sato, Takashi, ...
Chondromodulin I (ChM-I) was supposed from its limited expression in cartilage and its functions in cultured chondrocytes as a major regulator in cartilage development. Here, we generated mice...
Suppressive function of androgen receptor in bone resorption
Kawano, Hirotaka, Sato, Takashi, Yamada, Takashi, Matsumoto, Takahiro, Sekine, Keisuke, Watanabe, Tomoyuki, ...
As locally converted estrogen from testicular testosterone contributes to apparent androgen activity, the physiological significance of androgen receptor (AR) function in the beneficial effects of...
Brain masculinization requires androgen receptor function
Sato, Takashi, Matsumoto, Takahiro, Kawano, Hirotaka, Watanabe, Tomoyuki, Uematsu, Yoshikatsu, Sekine, Keisuke, ...
Testicular testosterone produced during a critical perinatal period is thought to masculinize and defeminize the male brain from the inherent feminization program and induce male-typical behaviors in...
Interactions between Sox9 and β-catenin control chondrocyte differentiation
Akiyama, Haruhiko, Lyons, Jon P., Mori-Akiyama, Yuko, Yang, Xiaohong, Zhang, Ren, Zhang, Zhaoping, ...
Chondrogenesis is a multistep process that is essential for endochondral bone formation. Previous results have indicated a role for β-catenin and Wnt signaling in this pathway. Here we show the...
Hata, Hiroshi, Sakaguchi, Noriko, Yoshitomi, Hiroyuki, Iwakura, Yoichiroh, Sekikawa, Kenji, Azuma, Yoshiaki, ...
Cytokines play key roles in spontaneous CD4+ T cell–mediated chronic autoimmune arthritis in SKG mice, a new model of rheumatoid arthritis. Genetic deficiency in IL-6 completely suppressed the...
Kuroki, Hiroshi, Nakagawa, Yasuaki, Mori, Koji, Ohba, Mao, Suzuki, Takashi, Mizuno, Yasuyuki, ...
We investigated quantitative changes over time in ultrasound signal intensity (an index of stiffness), signal duration (an index of surface irregularity), and interval between signals (an index of...
Kiyohara, Masashi, Sakaguchi, Keishi, Yamaguchi, Kuniko, Araki, Toshiyoshi, Nakamura, Takashi, Ito, Makoto
We cloned a novel β-1,3-xylanase gene, consisting of a 1728-bp open reading frame encoding 576 amino acid residues, from a marine bacterium, Vibrio sp. strain AX-4. Sequence analysis revealed that...
Kita, Katsuhiro, Sueyoshi, Noriyuki, Okino, Nozomu, Inagaki, Masanori, Ishida, Hideharu, Kiso, Makoto, ...
We have reported previously that the ceramidase from Pseudomonas aeruginosa AN17 isolated from a patient with atopic dermatitis requires detergents for hydrolysis of ceramide (Cer) [Okino, Tani,...
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors
Akiyama‡, Haruhiko, Kim‡, Jung-Eun, Nakashima, Kazuhisa, Balmes, Gener, Iwai, Naomi, Deng, Jian Min, ...
The transcription factor Sox9 is expressed in all chondroprogenitors and has an essential role in chondrogenesis. Sox9 is also expressed in other tissues, including central nervous system, neural...
Premature ovarian failure in androgen receptor-deficient mice
Shiina, Hiroko, Matsumoto, Takahiro, Sato, Takashi, Igarashi, Katsuhide, Miyamoto, Junko, Takemasa, Sayuri, ...
Premature ovarian failure (POF) syndrome, an early decline of ovarian function in women, is frequently associated with X chromosome abnormalities ranging from various Xq deletions to complete loss of...
Aihara, Ken-ichi, Azuma, Hiroyuki, Akaike, Masashi, Ikeda, Yasumasa, Sata, Masataka, Takamori, Nobuyuki, ...
Heparin cofactor II (HCII) specifically inhibits thrombin action at sites of injured arterial wall, and patients with HCII deficiency exhibit advanced atherosclerosis. However, the in vivo effects...
A Novel Type of EWS-CHOP Fusion Gene in Two Cases of Myxoid Liposarcoma
Hosaka, Taisuke, Nakashima, Yasuaki, Kusuzaki, Katsuyuki, Murata, Hiroaki, Nakayama, Tomitaka, Nakamata, Takeharu, ...
Fusion genes consisting of TLS/FUS and CHOP or EWS and CHOP are characteristic markers for myxoid/round cell liposarcomas (MLS/RCLS). Several different structures of the fusion genes were reported in...
Bioactive and bioresorbable cellular cubic-composite scaffolds for use in bone reconstruction
Shikinami, Yasuo, Okazaki, Kenshi, Saito, Makoto, Okuno, Masaki, Hasegawa, Shin, Tamura, Jiro, ...
We used a novel composite fibre-precipitation method to create bioactive and bioresorbable cellular cubic composites containing calcium phosphate (CaP) particles (unsintered and uncalcined...
Fukumoto, Satoshi, Kiba, Takayoshi, Hall, Bradford, Iehara, Noriyuki, Nakamura, Takashi, Longenecker, Glenn, ...
Tooth morphogenesis results from reciprocal interactions between oral epithelium and ectomesenchyme culminating in the formation of mineralized tissues, enamel, and dentin. During this process,...
Yoshitomi, Hiroyuki, Sakaguchi, Noriko, Kobayashi, Katsuya, Brown, Gordon D., Tagami, Tomoyuki, Sakihama, Toshiko, ...
A combination of genetic and environmental factors can cause autoimmune disease in animals. SKG mice, which are genetically prone to develop autoimmune arthritis, fail to develop the disease under a...
Hirota, Keiji, Yoshitomi, Hiroyuki, Hashimoto, Motomu, Maeda, Shinji, Teradaira, Shin, Sugimoto, Naoshi, ...
This report shows that interleukin (IL) 17–producing T helper type 17 (Th17) cells predominantly express CC chemokine receptor (CCR) 6 in an animal model of rheumatoid arthritis (RA). Th17 cells...
Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation
Kimura, Hiroaki, Kwan, Kin Ming, Zhang, Zhaoping, Deng, Jian Min, Darnay, Bryant G., Behringer, Richard R., ...
Kuroki, Hiroshi, Nakagawa, Yasuaki, Mori, Koji, Kobayashi, Masahiko, Yasura, Ko, Okamoto, Yukihiro, ...
Tominaga, Hiroyuki, Maeda, Shingo, Hayashi, Makoto, Takeda, Shu, Akira, Shizuo, Komiya, Setsuro, ...
Although CCAAT/enhancer-binding protein β (C/EBPβ) is involved in osteocalcin gene expression in osteoblast in vitro, the physiological importance of and molecular mechanisms governing C/EBPβ in...
Kuroki, Hiroshi, Nakagawa, Yasuaki, Mori, Koji, Kobayashi, Masahiko, Yasura, Ko, Okamoto, Yukihiro, ...
Fully functional bioengineered tooth replacement as an organ replacement therapy
Ikeda, Etsuko, Morita, Ritsuko, Nakao, Kazuhisa, Ishida, Kentaro, Nakamura, Takashi, Takano-Yamamoto, Teruko, ...
Current approaches to the development of regenerative therapies have been influenced by our understanding of embryonic development, stem cell biology, and tissue engineering technology. The ultimate...
Neuronal Differentiation of Synovial Sarcoma and Its Therapeutic Application
Ishibe, Tatsuya, Nakayama, Tomitaka, Aoyama, Tomoki, Nakamura, Takashi, Toguchida, Junya
Synovial sarcoma is a rare sarcoma of unknown histologic origin. We previously reported the gene expression profile of synovial sarcoma was closely related to that of malignant peripheral nerve...
Iwasawa, Mitsuyasu, Miyazaki, Tsuyoshi, Nagase, Yuichi, Akiyama, Toru, Kadono, Yuho, Nakamura, Masaki, ...
The B cell lymphoma 2 (Bcl-2) family member Bcl-xL has a well-characterized antiapoptotic function in lymphoid cells. However, its functions in other cells — including osteoclasts, which are of...