須田, 年生, スダ, トシオ, SUDA, TOSHIO, 新井, 文用, アライ, フミオ, ARAI, FUMIO, ...
Research team head
Sawatani, Yumi, Miyamoto, Takeshi, Nagai, Shigenori, Maruya, Mikako, Imai, Jun, Miyamoto, Kana, ...
Regulation of dendritic cell (DC) function is critical for maintaining self-tolerance and preventing autoimmunity. The dendritic cell-specific transmembrane protein (DC-STAMP) plays a key role in...
Photochemical Method of Device Fabrication Starting from Molecular Crystals (2006)
Naito, Toshio, Sugawara, Hideyuki, Inabe, Tamotsu, Miyamoto, Takeshi, Niimi, Hironobu, Asakura, Kiyotaka
The conductivity of a silver salt of N,N'-dicyanoquinonediimine irreversibly varied in approximate proportion to an illumination of a wide range of wavelengths. Depending on the illumination...
Photochemical fabrication of molecular devices (2006)
Naito, Toshio, Sugawara, Hideyuki, Inabe, Tamotsu, Miyamoto, Takeshi, Niimi, Hironobu, Asakura, Kiyotaka
We present a novel way to fabricate electronic devices from a molecular charge transfer salt Ag(DM)2 by simple illumination, which realizes a junction-structure in the single molecular crystal. The...
Photochemical fabrication of molecular devices (2006)
Naito, Toshio, Sugawara, Hideyuki, Inabe, Tamotsu, Miyamoto, Takeshi, Niimi, Hironobu, Asakura, Kiyotaka
We present a novel way to fabricate electronic devices from a molecular charge transfer salt Ag(DM)2 by simple illumination, which realizes a junction-structure in the single molecular crystal. The...
Photochemical fabrication of molecular devices (2006)
Naito, Toshio, Sugawara, Hideyuki, Inabe, Tamotsu, Miyamoto, Takeshi, Niimi, Hironobu, Asakura, Kiyotaka
We present a novel way to fabricate electronic devices from a molecular charge transfer salt Ag(DM)2 by simple illumination, which realizes a junction-structure in the single molecular crystal. The...
Prolonged skin allograft survival by IL-10 gene-introduced CD4 T cell administration (2005)
Miyamoto, Takeshi, Kaneko, Takaaki, Yamashita, Masakatsu, Tenda, Yoshiyuki, Inami, Masamichi, Suzuki, Akane, ...
Both CD4 and CD8 T cells play crucial roles in immune responses in transplantation. Immunosuppressive drugs, such as FK506 and cyclosporin A, block the priming of alloreactive CD4 Th cells and the...
Prolonged skin allograft survival by IL-10 gene-introduced CD4 T cell administration (2005)
Miyamoto, Takeshi, Kaneko, Takaaki, Yamashita, Masakatsu, Tenda, Yoshiyuki, Inami, Masamichi, Suzuki, Akane, ...
Both CD4 and CD8 T cells play crucial roles in immune responses in transplantation. Immunosuppressive drugs, such as FK506 and cyclosporin A, block the priming of alloreactive CD4 Th cells and the...
Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development
Kubota, Yoshiaki, Oike, Yuichi, Satoh, Shinya, Tabata, Yoko, Niikura, Yuichi, Morisada, Tohru, ...
Angiopoietin-like protein (Angptl) 1 and Angptl2, which are considered orphan ligands, are highly homologous, particularly in the fibrinogen-like domain containing the putative receptor binding site....
Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development
Kubota, Yoshiaki, Oike, Yuichi, Satoh, Shinya, Tabata, Yoko, Niikura, Yuichi, Morisada, Tohru, ...
Angiopoietin-like protein (Angptl) 1 and Angptl2, which are considered orphan ligands, are highly homologous, particularly in the fibrinogen-like domain containing the putative receptor binding site....
Saika, Shizuya, Miyamoto, Takeshi, Yamanaka, Osamu, Kato, Tadashi, Ohnishi, Yoshitaka, Flanders, Kathleen C., ...
We evaluated the therapeutic efficacy of topical administration of SN50, an inhibitor of nuclear factor-κB, in a corneal alkali burn model in mice. An alkali burn was produced with 1 N NaOH in the...
Expression of Smad7 in Mouse Eyes Accelerates Healing of Corneal Tissue after Exposure to Alkali
Saika, Shizuya, Ikeda, Kazuo, Yamanaka, Osamu, Miyamoto, Takeshi, Ohnishi, Yoshitaka, Sato, Misako, ...
Damage to the cornea from chemical burns is a serious clinical problem that often leads to permanent visual impairment. Because transforming growth factor (TGF)-β has been implicated in the response...
Saika, Shizuya, Ikeda, Kazuo, Yamanaka, Osamu, Flanders, Kathleen C., Okada, Yuka, Miyamoto, Takeshi, ...
Animal cornea is an avascular transparent tissue that is suitable for research on wound healing-related scarring and neovascularization. Here we show that loss of tumor necrosis factor α (TNFα)...
Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification
Morita, Kozo, Miyamoto, Takeshi, Fujita, Nobuyuki, Kubota, Yoshiaki, Ito, Keisuke, Takubo, Keiyo, ...
Chondrocyte hypertrophy during endochondral ossification is a well-controlled process in which proliferating chondrocytes stop proliferating and differentiate into hypertrophic chondrocytes, which...
DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells
Yagi, Mitsuru, Miyamoto, Takeshi, Sawatani, Yumi, Iwamoto, Katsuya, Hosogane, Naobumi, Fujita, Nobuyuki, ...
Osteoclasts are bone-resorbing cells that play a pivotal role in bone remodeling. Osteoclasts form large multinuclear giant cells by fusion of mononuclear osteoclasts. How cell fusion is mediated,...
Arai, Fumio, Ohneda, Osamu, Miyamoto, Takeshi, Zhang, Xiu Qin, Suda, Toshio
Perichondrium in fetal limb is composed of undifferentiated mesenchymal cells. However, the multipotency of cells in this region and the role of perichondrium in bone marrow formation are not well...
Arai, Fumio, Miyamoto, Takeshi, Ohneda, Osamu, Inada, Tomohisa, Sudo, Tetsuo, Brasel, Kenneth, ...
Osteoclasts are terminally differentiated cells derived from hematopoietic stem cells. However, how their precursor cells diverge from macrophagic lineages is not known. We have identified early and...
Hirose, Yuichiro, Chiba, Kazuhiro, Karasugi, Tatsuki, Nakajima, Masahiro, Kawaguchi, Yoshiharu, Mikami, Yasuo, ...
Lumbar-disc herniation (LDH), one of the most common musculoskeletal diseases, has strong genetic determinants. Recently, several genes that encode extracellular matrix (ECM) proteins in the...