Betancur, Catalina, Sakurai, Takeshi, Buxbaum, Joseph D
Recent advances in genetics and genomics have unveiled numerous cases of autism spectrum disorders (ASDs) associated with rare, causal genetic variations. These findings support a novel view of ASDs...
Betancur, Catalina, Sakurai, Takeshi, Buxbaum, Joseph D
Recent advances in genetics and genomics have unveiled numerous cases of autism spectrum disorders (ASDs) associated with rare, causal genetic variations. These findings support a novel view of ASDs...
Betancur, Catalina, Sakurai, Takeshi, Buxbaum, Joseph D
Recent advances in genetics and genomics have unveiled numerous cases of autism spectrum disorders (ASDs) associated with rare, causal genetic variations. These findings support a novel view of ASDs...
Yamauchi, Taro, Lekprichakul, Thamana, Sakurai, Takeshi, Kanno, Hiromitsu, Umetsu, Chieko, Sokotela, Sesele
The nutritional status, growth, and health of children are useful indicators for assessing the ability of a population to adapt to the environment and the extent of this adaptation. These indicators...
Tomoko Yamagata, Takeshi Sakurai, Keiro Uchino, Hideki Sezutsu, Toshiki Tamura, Ryohei Kanzaki
The microbrain of the silkmoth, Bombyx mori, is a model system for analyzing the neural mechanisms underlying stimulus-driven behavior, and numerous studies using physiological and morphological...
Takeshi Sakurai, Taizo Matsuki, Hitomi Takahira, Noriko Hirashima, Thomas Kilduff, Satoshi Kunita, ...
We generated mice with a selective loss of GABAB receptors in orexin neurons. Orexin neurons in these GABAB1<sup>-/-(orexin)</sup> mice showed reduced responsiveness to...
片岡, 邦重, Kataoka, Kunishige, Tanaka, Kazuhiro, Sakai, Yoko, Sakurai, Takeshi
Bilirubin oxidase (BO) from Myrothecium verrucaria (authentic BO) catalyzing the oxidation of bilirubin to biliverdine was overexpressed in the methylotrophic yeast, Pichia pastoris. The cDNA...
Type III Cu Mutants of Myrothecium verrucaria Bilirubin Oxidase (2003)
Shimizu, Atsushi, Samejima, Tatsuya, Hirota, Shun, Yamaguchi, Shotaro, Sakurai, Nobuhiko, Sakurai, Takeshi
Type III Cu ligand, His456 and His458, of Myrothecium verrucaria (MT-1) bilirubin oxidases (BO) [EC 1.3.3.5] were doubly mutated as to Lys, Asp, and Val. In spite of perturbation of the...
"Demand for rice in West Africa has been growing at 5.6% a year, not only driven by population growth but also due to a shift in diet away from traditional coarse grains caused by urbanization. The...
Zoppellaro, Giorgio, Sakurai, Takeshi, Huang, Hong-wei
Rhus vernicifera laccase, in a novel mixed valence state [TloxT23red: type 1 Cu as Cu(II), and type 2 and 3 Cus as Cu(I)], was formed by reacting Cu(I) on the type 2 Cu-depleted laccase [T1oxT3red:...
Yasumi Uchida, Yoshiharu Fujimori, Hidefumi Ohsawa, Jyunichi Hirose, Hirofumi Noike, Keiichi Tokuhiro, ...
Background Since long-term administrations of anti-hyperlipidemic agents result in reduction in % stenosis or increase in minimum lumen diameter (MLD) of stenotic coronary segments, it is generally...
Percutaneous Dye Image Cardioscopy for Detection of Endocardial Lesions (2000)
Masahito Kanai, Takeshi Sakurai, Kunio Yoshinaga, Kaneyuki Aoyagi, Takashi Hitsumoto, Masaki Yoshinuma, ...
Endocardial lesions are caused not only by inflammatory processes but also by myocardial ischemia, resulting in endocardial thrombosis and cerebral embolism. We deviced a method for direct...
Shimizu, Atsushi, Sasaki, Takashi, Kwon, Jung Hee, Odaka, Akito, Satoh, Takanori, Sakurai, Nobuhiko, ...
In our previous paper, we reported a mutant of recombinant Myrothecium verrucaria bilirubin oxidase, in which the Met467 residue was replaced by Gly [Shimizu, A, et al. (1999) Biochemistry 38,...
Essays on uncertainty and sustainability in the semi-arid tropics /--by Takeshi Sakurai. (1995)
Thesis (Ph. D.)--Michigan State University. Dept. of Agricultural Economics, 1995.
Essays on uncertainty and sustainability in the semi-arid tropics / (1995)
Thesis (Ph. D.)--Michigan State University. Dept. of Agricultural Economics, 1995.
Characterization of Ascorbate Oxidase from Acremonium sp. HI-25 (1994)
Hirose, Junzo, Sakurai, Takeshi, Imamura, Kaori, Watanabe, Hideomi, Iwamoto, Hiroyuki, Hiromi, Keitaro, ...
The ascorbate oxidase obtained from a microorganism, Acremonium sp. HI-25 (molecular weight, 80 k Da; monomeric protein), was studied with respect to atomic absorption, EPR, absorption spectra,...
Sakurai, Takeshi, Suzuki, Shinnichiro, Chikira, Makoto
The present study shows that the electron spin resonance (ESR) spectral features of Rhuslaccase depend considerably on the pH value of the enzyme solution and the irradiated microwave power. Because...
Characterization of Plastocyanin Isolated From Brazilian Elodea (1987)
Suzuki, Shinnichiro, Sakurai, Takeshi, Nakajima, Takuo
Plastocyanin obtained from an aquatic higher plant, Brazilian elodea, was characterized by electronic absorption, CD, and EPR spectroscopy. The blue copper center of Brazilian elodea plastocyanin is...
MASUKO, Masayuki, IWASAKI, Hidekazu, SAKURAI, Takeshi, SUZUKI, Shinnichiro, NAKAHARA, Akitsugu
The effects of freezing on Alcaligenes sp. nitrite reductase [nitric-oxide: ferricytochrome c oxidoreductase, EC 1.7.2.1] dissolved in sodium phosphate (pH 7.2) were investigated. The nitrite...
MASUKO, Masayuki, IWASAKI, Hidekazu, SAKURAI, Takeshi, SUZUKI, Shinnichiro, NAKAHARA, Akitsugu
A copper-containing dissimilatory nitrite reductase [nitric-oxide: ferricytochrome c oxidoreductase, EC 1.7.2.11 was purified from a denitrifier, Alcaligenes sp. NCIB 11015, by ion-exchange...
Preparation and Characterization of Cobalt(II)-Substituted Bovine Serum Amine Oxidase (1981)
SUZUKI, Shinnichiro, SAKURAI, Takeshi, NAKAHARA, Akitsugu, ODA, Osamu, MANABE, Takashi, OKUYAMA, Tsuneo
The Type-2 copper ion in bovine serum amine oxidase (BSAO) was first replaced by cobalt(II) ion. The enzymatic activity of Co(II)BSAO was 13.3% of that of native BSAO. The various spectral data...
Date, Yukari, Ueta, Yoichi, Yamashita, Hiroshi, Yamaguchi, Hideki, Matsukura, Shigeru, Kangawa, Kenji, ...
We determined the immunohistochemical distributions of orexin-A and orexin-B, hypothalamic peptides that function in the regulation of feeding behavior and energy homeostasis. Orexin-A and -B neurons...
Cloning and characterization of a novel endothelin receptor subtype in the avian class
Lecoin, Laure, Sakurai, Takeshi, Ngo, Minh-Triet, Abe, Yoichiro, Yanagisawa, Masashi, Le Douarin, Nicole M.
Endothelin 3 (EDN 3) and the endothelin receptor B (EDNRB) are involved in the development of neural crest and particularly of the melanocytes and the enteric nervous system. We reported previously...
Ichiki, Hirotaka, Tanaka, Yoko, Mochizuki, Kiyotaka, Yoshimatsu, Katsuhiko, Sakurai, Takeshi, Fujiwara, Taketomo
Cu-containing dissimilatory nitrite reductase (CuNiR) was purified from denitrifying cells of a halophilic archaeon, Haloarcula marismortui. The purified CuNiR appeared blue in the oxidized state,...
Tanaka, Hirokazu, Yoshida, Tetsuo, Miyamoto, Norimasa, Motoike, Toshiyuki, Kurosu, Hiroshi, Shibata, Kenji, ...
GPR7 and GPR8 are orphan G protein-coupled receptors that are highly similar to each other. These receptors are expressed predominantly in brain, suggesting roles in central nervous system function....
Mieda, Michihiro, Willie, Jon T., Hara, Junko, Sinton, Christopher M., Sakurai, Takeshi, Yanagisawa, Masashi
Narcolepsy-cataplexy is a neurological disorder associated with the inability to maintain wakefulness and abnormal intrusions of rapid eye movement sleep-related phenomena into wakefulness such as...
Sakurai, Takeshi, Nakagawa, Takao, Mitsuno, Hidefumi, Mori, Hajime, Endo, Yasuhisa, Tanoue, Shintarou, ...
Sex pheromones released by female moths are detected with high specificity and sensitivity in the olfactory sensilla of antennae of conspecific males. Bombykol in the silkmoth Bombyx mori was the...
Yanagita, Motoko, Okuda, Tomohiko, Endo, Shuichiro, Tanaka, Mari, Takahashi, Katsu, Sugiyama, Fumihiro, ...
Dialysis dependency is one of the leading causes of morbidity and mortality in the world, and once end-stage renal disease develops, it cannot be reversed by currently available therapy. Although...
Whittard, John D., Sakurai, Takeshi, Cassella, Melanie R., Gazdoiu, Mihaela, Felsenfeld, Dan P.
The growth of neuronal processes depends critically on the function of adhesion proteins that link extracellular ligands to the cytoskeleton. The neuronal adhesion protein L1-CAM serves as a receptor...
Efficiency of timber production in community and private forestry in Nepal
SAKURAI, TAKESHI, RAYAMAJHI, SANTOSH, POKHAREL, RIDISH K., OTSUKA, KEIJIRO
This study compares the management performance of timber production among three management systems in Nepal: private forestry, community forestry with collective management, and community forestry...
Efficiency and equity in groundwater markets: the case of Madhya Pradesh, India
This paper examines efficiency and equity in groundwater markets with special attention to output sharing contracts and to the bargaining relationships between sellers and buyers, using household...
Takayasu, Shinobu, Sakurai, Takeshi, Iwasaki, Satoshi, Teranishi, Hitoshi, Yamanaka, Akihiro, Williams, S. Clay, ...
Here, we report the isolation and characterization of an endogenous peptide ligand of GPR103 from rat brains. The purified peptide was found to be the 43-residue RF-amide peptide QRFP. We also...
Date, Yukari, Ueta, Yoichi, Yamashita, Hiroshi, Yamaguchi, Hideki, Matsukura, Shigeru, Kangawa, Kenji, ...
We determined the immunohistochemical distributions of orexin-A and orexin-B, hypothalamic peptides that function in the regulation of feeding behavior and energy homeostasis. Orexin-A and -B neurons...
Cloning and characterization of a novel endothelin receptor subtype in the avian class
Lecoin, Laure, Sakurai, Takeshi, Ngo, Minh-Triet, Abe, Yoichiro, Yanagisawa, Masashi, Le Douarin, Nicole M.
Endothelin 3 (EDN 3) and the endothelin receptor B (EDNRB) are involved in the development of neural crest and particularly of the melanocytes and the enteric nervous system. We reported previously...
Ichiki, Hirotaka, Tanaka, Yoko, Mochizuki, Kiyotaka, Yoshimatsu, Katsuhiko, Sakurai, Takeshi, Fujiwara, Taketomo
Cu-containing dissimilatory nitrite reductase (CuNiR) was purified from denitrifying cells of a halophilic archaeon, Haloarcula marismortui. The purified CuNiR appeared blue in the oxidized state,...
Tanaka, Hirokazu, Yoshida, Tetsuo, Miyamoto, Norimasa, Motoike, Toshiyuki, Kurosu, Hiroshi, Shibata, Kenji, ...
GPR7 and GPR8 are orphan G protein-coupled receptors that are highly similar to each other. These receptors are expressed predominantly in brain, suggesting roles in central nervous system function....
Mieda, Michihiro, Willie, Jon T., Hara, Junko, Sinton, Christopher M., Sakurai, Takeshi, Yanagisawa, Masashi
Narcolepsy-cataplexy is a neurological disorder associated with the inability to maintain wakefulness and abnormal intrusions of rapid eye movement sleep-related phenomena into wakefulness such as...
Sakurai, Takeshi, Nakagawa, Takao, Mitsuno, Hidefumi, Mori, Hajime, Endo, Yasuhisa, Tanoue, Shintarou, ...
Sex pheromones released by female moths are detected with high specificity and sensitivity in the olfactory sensilla of antennae of conspecific males. Bombykol in the silkmoth Bombyx mori was the...
Yanagita, Motoko, Okuda, Tomohiko, Endo, Shuichiro, Tanaka, Mari, Takahashi, Katsu, Sugiyama, Fumihiro, ...
Dialysis dependency is one of the leading causes of morbidity and mortality in the world, and once end-stage renal disease develops, it cannot be reversed by currently available therapy. Although...
Takayasu, Shinobu, Sakurai, Takeshi, Iwasaki, Satoshi, Teranishi, Hitoshi, Yamanaka, Akihiro, Williams, S. Clay, ...
Here, we report the isolation and characterization of an endogenous peptide ligand of GPR103 from rat brains. The purified peptide was found to be the 43-residue RF-amide peptide QRFP. We also...
Whittard, John D., Sakurai, Takeshi, Cassella, Melanie R., Gazdoiu, Mihaela, Felsenfeld, Dan P.
The growth of neuronal processes depends critically on the function of adhesion proteins that link extracellular ligands to the cytoskeleton. The neuronal adhesion protein L1-CAM serves as a receptor...
GABAB receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus
Xie, Xinmin, Crowder, Tara L, Yamanaka, Akihiro, Morairty, Stephen R, LeWinter, Robin D, Sakurai, Takeshi, ...
Hypocretin/orexin (Hcrt) is a critical neurotransmitter for the maintenance of wakefulness and has been implicated in several other functions, including energy metabolism and reward. Using whole-cell...
Kei Kajisa, K. Palanisami, Takeshi Sakurai
This paper investigates the factors influencing the decline in collective management of local commons and the impact of this decline on agricultural production and household consumption. The analysis...
Sakurai, Takeshi, Lustig, Marc, Nativ, Moshe, Hemperly, John J., Schlessinger, Joseph, Peles, Elior, ...
Receptor protein tyrosine phosphatase β (RPTPβ) is expressed as soluble and receptor forms with common extracellular regions consisting of a carbonic anhydrase domain (C), a fibronectin type III...
Sakurai, Takeshi, Lustig, Marc, Babiarz, Joanne, Furley, Andrew J.W., Tait, Steven, Brophy, Peter J., ...
The structurally related cell adhesion molecules L1 and Nr-CAM have overlapping expression patterns in cerebellar granule cells. Here we analyzed their involvement in granule cell development using...
Gil, Orlando D., Sakurai, Takeshi, Bradley, Ann E., Fink, Marc Y., Cassella, Melanie R., Kuo, James A., ...
The function of adhesion receptors in both cell adhesion and migration depends critically on interactions with the cytoskeleton. During cell adhesion, cytoskeletal interactions stabilize receptors to...
Percutaneous Dye Image Cardioscopy for Detection of Endocardial Lesions
Kanai, Masahito, Sakurai, Takeshi, Yoshinaga, Kunio, Aoyagi, Kaneyuki, Hitsumoto, Takashi, Yoshinuma, Masaki, ...
Endocardial lesions are caused not only by inflammatory processes but also by myocardial ischemia, resulting in endocardial thrombosis and cerebral embolism. We deviced a method for direct...
Uchida, Yasumi, Fujimori, Yoshiharu, Ohsawa, Hidefumi, Hirose, Jyunichi, Noike, Hirofumi, Tokuhiro, Keiichi, ...
Background Since long-term administrations of anti-hyperlipidemic agents result in reduction in % stenosis or increase in minimum lumen diameter (MLD) of stenotic coronary segments, it is generally...
Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy
Zhang, Shengwen, Zeitzer, Jamie M, Sakurai, Takeshi, Nishino, Seiji, Mignot, Emmanuel
Recent population studies have identified important interrelationships between sleep duration and body weight regulation. The hypothalamic hypocretin/orexin neuropeptide system is able to influence...
Xie, Xinmin, Wisor, Jonathan P., Hara, Junko, Crowder, Tara L., LeWinter, Robin, Khroyan, Taline V., ...
Stress-induced analgesia (SIA) is a key component of the defensive behavioral “fight-or-flight” response. Although the neural substrates of SIA are incompletely understood, previous studies have...
WHEAT IMPORT DEMAND IN THE JAPANESE FLOUR MILLING INDUSTRY: A PRODUCTION THEORY APPROACH
Weining MAO, Won W. KOO, Jon P. SUOMALA, Takeshi SAKURAI
The translog cost function is used to analyze import demand for wheat differentiated by class and country of origin in the Japanese wheat flour milling industry. Results indicate that U.S. wheat...
Biotechnology, especially genetic engineering, is a revolutionary tool in life-science research. When it came, people thought it would have the greatest impact both on pharmaceutical and agriculture...
WHEAT IMPORT DEMAND IN THE JAPANESE FLOUR MILLING INDUSTRY: A PRODUCTION THEORY APPROACH
Mao, Weining, Koo, Won W., Suomala, Jon P., Sakurai, Takeshi
The translog cost function is used to analyze import demand for wheat differentiated by class and country of origin in the Japanese wheat flour milling industry. Results indicate that U.S. wheat...
INTERLINKAGE IN THE RICE MARKET OF GHANA: MONEY-LENDING MILLERS ENHANCE EFFICIENCY
Most of the large-scale millers in Ghana provide a loan to the farmers under the agreement that the farmers will bring their paddy to them. This paper examines the effect of this interlinkage on the...
Rice Miller Cluster in Ghana and Its Effects on Efficiency and Quality Improvement
Sakurai, Takeshi, Furuya, Jun, Futakuchi, Koichi
This paper investigates the roles of industrial cluster on the efficiency of rice milling and the improvement of milled rice quality. The data were obtained in Kumasi area, central Ghana because the...
Kajisa, Kei, Palanisami, K., Sakurai, Takeshi
This paper investigates the impact of the dissemination of modern irrigation systems, i.e. private wells with pumps, on the livelihood not only among the farmers who have access to wells but also...
Identification of a population of sleep-active cerebral cortex neurons
Gerashchenko, Dmitry, Wisor, Jonathan P., Burns, Deirdre, Reh, Rebecca K., Shiromani, Priyattam J., Sakurai, Takeshi, ...
The presence of large-amplitude, slow waves in the EEG is a primary characteristic that distinguishes cerebral activity during sleep from that which occurs during wakefulness. Although sleep-active...
IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin)
Honda, Makoto, Eriksson, Krister S., Zhang, Shengwen, Tanaka, Susumu, Lin, Ling, Salehi, Ahmad, ...
Mishima, Kazuo, Fujiki, Nobuhiro, Yoshida, Yasushi, Sakurai, Takeshi, Honda, Makoto, Mignot, Emmanuel, ...
Höistad, Malin, Segal, Devorah, Takahashi, Nagahide, Sakurai, Takeshi, Buxbaum, Joseph D., Hof, Patrick R.
Neuronal circuitry relies to a large extent on the presence of functional myelin produced in the brain by oligodendrocytes. Schizophrenia has been proposed to arise partly from altered brain...
Irukayama-Tomobe, Yoko, Tanaka, Hirokazu, Yokomizo, Takehiko, Hashidate-Yoshida, Tomomi, Yanagisawa, Masashi, Sakurai, Takeshi
GPR109B (HM74) is a putative G protein-coupled receptor (GPCR) whose cognate ligands have yet to be characterized. GPR109B shows a high degree of sequence similarity to GPR109A, another GPCR that was...
Matsuki, Taizo, Nomiyama, Mika, Takahira, Hitomi, Hirashima, Noriko, Kunita, Satoshi, Takahashi, Satoru, ...
Hypothalamic neurons that contain the neuropeptide orexin (hypocretin) play important roles in the regulation of sleep/wake. Here we analyze the in vivo and in vitro phenotype of mice lacking the...