Takeshi Yamada

New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum (2009)

Takeshi Yamada, Yasuhide Muroga, Reiko Tanaka

Seco-chaetomugilins A and D were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on...

No Increased Incidence of Chromosomal Aberrations in Human Spermatozoa with Large Vacuoles by Injection into Mouse Oocytes (2008)

Seiji Watanabe, Hideki Mizunuma, Shunsaku Fujii, Atsushi Fukui, Hidenori Kimura, Rie Fukuhara, ...

The effect of IMSI on avoiding fertilization with chromosomally abnormal sperm was examined in the present study. Normal shaped human sperm with large vacuoles were identified at 1,000×...

scheduling (2008)

Takeshi Yamada

pruning pattern list approach to the permutation flowshop

Modeling User Behavior in Recommender Systems based on Maximum Entropy ABSTRACT (2008)

Tomoharu Iwata, Kazumi Saito, Takeshi Yamada

We propose a model for user purchase behavior in online stores that provide recommendation services. We model the purchase probability given recommendations for each user based on the maximum entropy...

Objective Estimation of Word Intelligibility for Noise-Reduced Speech (2008)

YAMADA, Takeshi, KUMAKURA, Masakazu, KITAWAKI, Nobuhiko

It is essential to ensure a satisfactory QoS (Quality of Service) when offering a speech communication system with a noise reduction algorithm. In this paper, we propose a new obejective test...

Extracting Communities from Complex Networks by the k-Dense Method (2008)

SAITO, Kazumi, YAMADA, Takeshi, KAZAMA, Kazuhiro

To understand the structural and functional properties of large-scale complex networks, it is crucial to efficiently extract a set of cohesive subnetworks as communities. There have been proposed...

Changes in the spontaneous calcium oscillations for the development of the preconditioning-induced ischemic tolerance in neuron/astrocyte co-culture. (2007)

Tanaka, Motoki, Kawahara, Koichi, Kosugi, Tatsuro, Yamada, Takeshi, Mioka, Tetsuo

Spontaneous Ca2+ oscillations are believed to contribute to the regulation of gene expression. Here we investigated whether and how the dynamics of Ca2+ oscillations changed after sublethal...

Changes in the spontaneous calcium oscillations for the development of the preconditioning-induced ischemic tolerance in neuron/astrocyte co-culture. (2007)

Tanaka, Motoki, Kawahara, Koichi, Kosugi, Tatsuro, Yamada, Takeshi, Mioka, Tetsuo

Spontaneous Ca2+ oscillations are believed to contribute to the regulation of gene expression. Here we investigated whether and how the dynamics of Ca2+ oscillations changed after sublethal...

Nitric Oxide Produced During Sublethal Ischemia Is Crucial for the Preconditioning-Induced Down-Regulation of Glutamate Transporter GLT-1 in Neuron/Astrocyte Co-Cultures (2006)

Yamada, Takeshi, Kawahara, Koichi, Kosugi, Tatsuro, Tanaka, Motoki, 河原, 剛一

In the brain, prior sublethal ischemia (preconditioning, PC) produces tolerance of neurons to subsequent lethal ischemia. This study aims at elucidating whether and how nitric oxide (NO) produced...

Nitric Oxide Produced During Sublethal Ischemia Is Crucial for the Preconditioning-Induced Down-Regulation of Glutamate Transporter GLT-1 in Neuron/Astrocyte Co-Cultures (2006)

Yamada, Takeshi, Kawahara, Koichi, Kosugi, Tatsuro, Tanaka, Motoki

In the brain, prior sublethal ischemia (preconditioning, PC) produces tolerance of neurons to subsequent lethal ischemia. This study aims at elucidating whether and how nitric oxide (NO) produced...

Nitric Oxide Produced During Sublethal Ischemia Is Crucial for the Preconditioning-Induced Down-Regulation of Glutamate Transporter GLT-1 in Neuron/Astrocyte Co-Cultures (2006)

Yamada, Takeshi, Kawahara, Koichi, Kosugi, Tatsuro, Tanaka, Motoki

In the brain, prior sublethal ischemia (preconditioning, PC) produces tolerance of neurons to subsequent lethal ischemia. This study aims at elucidating whether and how nitric oxide (NO) produced...

Recommendation methods for extending subscription periods (2006)

Tomoharu Iwata, Kazumi Saito, Takeshi Yamada

Online stores providing subscription services need to extend user subscription periods as long as possible to increase their profits. Conventional recommendation methods recommend items that best...

Detection of Overlapping Speech in Meetings Using Support Vector Machines and Support Vector Regression (2006)

YAMAMOTO, Kiyoshi, ASANO, Futoshi, YAMADA, Takeshi, KITAWAKI, Nobuhiko

In this paper, a method of detecting overlapping speech segments in meetings is proposed. It is known that the eigenvalue distribution of the spatial correlation matrix calculated from a multiple...

Functional Significance of the Preconditioning-induced Down-regulation of Glutamate Transporter GLT-1 in Neuron/astrocyte Co-cultures (2005)

Kosugi, Tatsuro, Kawahara, Koichi, Yamada, Takeshi, Nakajima, Takayuki, Tanaka, Motoki, 河原, 剛一

In the brain, prior sublethal ischemia (preconditioning, PC) is known to produce tolerance of neurons to subsequent lethal ischemia. This study aims at elucidating what alterations were induced in...

Functional Significance of the Preconditioning-induced Down-regulation of Glutamate Transporter GLT-1 in Neuron/astrocyte Co-cultures (2005)

Kosugi, Tatsuro, Kawahara, Koichi, Yamada, Takeshi, Nakajima, Takayuki, Tanaka, Motoki

In the brain, prior sublethal ischemia (preconditioning, PC) is known to produce tolerance of neurons to subsequent lethal ischemia. This study aims at elucidating what alterations were induced in...

Functional Significance of the Preconditioning-induced Down-regulation of Glutamate Transporter GLT-1 in Neuron/astrocyte Co-cultures (2005)

Kosugi, Tatsuro, Kawahara, Koichi, Yamada, Takeshi, Nakajima, Takayuki, Tanaka, Motoki

In the brain, prior sublethal ischemia (preconditioning, PC) is known to produce tolerance of neurons to subsequent lethal ischemia. This study aims at elucidating what alterations were induced in...

Reversed operation of glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocyte co-cultures (2005)

Kawahara, Koichi, Kosugi, Tatsuro, Tanaka, Motoki, Nakajima, Takayuki, Yamada, Takeshi, 河原, 剛一

Sublethal ischemia leads to increased tolerance against subsequent prolonged cerebral ischemia in vivo. In the present study, we investigated the roles of the astrocytic glutamate (Glu) transporter...

Reversed operation of glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocyte co-cultures (2005)

Kawahara, Koichi, Kosugi, Tatsuro, Tanaka, Motoki, Nakajima, Takayuki, Yamada, Takeshi

Sublethal ischemia leads to increased tolerance against subsequent prolonged cerebral ischemia in vivo. In the present study, we investigated the roles of the astrocytic glutamate (Glu) transporter...

Suppression of Thymic Lymphoma Induction by Life-Long Low-Dose-Rate Irradiation Accompanied by Immune Activation in C57BL/6 Mice (2005)

Yasuhiro Ina, Hiroshi Tanooka, Takeshi Yamada, Kazuo Sakai

Ina, Y., Tanooka, H., Yamada, T. and Sakai, K. Suppression of Thymic Lymphoma Induction by Life-Long Low-Dose-Rate Irradiation Accompanied by Immune Activation in C57BL/6 Mice. Radiat. Res. 163,...

Reversed operation of glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocyte co-cultures (2005)

Kawahara, Koichi, Kosugi, Tatsuro, Tanaka, Motoki, Nakajima, Takayuki, Yamada, Takeshi

Sublethal ischemia leads to increased tolerance against subsequent prolonged cerebral ischemia in vivo. In the present study, we investigated the roles of the astrocytic glutamate (Glu) transporter...

AURORA-2J: An Evaluation Framework for Japanese Noisy Speech Recognition (2005)

NAKAMURA, Satoshi, TAKEDA, Kazuya, YAMAMOTO, Kazumasa, YAMADA, Takeshi, KUROIWA, Shingo, KITAOKA, Norihide, ...

This paper introduces an evaluation framework for Japanese noisy speech recognition named AURORA-2J. Speech recognition systems must still be improved to be robust to noisy environments, but this...

Objective Quality Assessment of Wideband Speech Coding (2005)

KITAWAKI, Nobuhiko, NAGAI, Kou, YAMADA, Takeshi

Recently, wideband speech communication using 7 kHz-wideband speech coding, as described in ITU-T Recommendations G.722, G.722.1, and G.722.2, has become increasingly necessary for use in advanced IP...

Asset price shocks, financial constraints, and investment : evidence from Japan (2004)

Goyal, Vidhan K., Yamada, Takeshi

We examine corporate investment spending around the asset price bubble in Japan in the late 1980s and make three contributions to our understanding of how stock valuations affect investment. First,...

Cross-entropy directed embedding of network data (2003)

Takeshi Yamada, Kazumi Saito, Naonori Ueda

We present a novel approach to embedding data represented by a network into a lowdimensional Euclidean space. Unlike existing methods, the proposed method attempts to minimize an energy function...

Studies on (2003)

Takeshi Yamada, Metaheuristics For, Flowshop Scheduling Problems, Takeshi Yamada

Scheduling has been a subject of a significant amount of literature in the operations research field since the early 1950s. The main objective of scheduling is an efficient allocation of shared...

Rescue of Lethally Irradiated Mice from Hematopoietic Death by Pre-exposure to 0.5 Gy X Rays without Recovery from Peripheral Blood Cell Depletion and its Modification by OK432 (2001)

Masako Nose, Bing Wang, Hiromi Itsukaichi, Osami Yukawa, Isamu Hayata, Takeshi Yamada, ...

Nose, M., Wang, B., Itsukaichi, H., Yukawa, O., Hayata, I., Yamada, T. and Ohyama, H. Rescue of Lethally Irradiated Mice from Hematopoietic Death by Pre-exposure to 0.5 Gy X Rays without Recovery...

Investor heterogeneity, trading volume and asset pricing / (2001)

Yamada, Takeshi

Thesis (Ph. D.)--University of California at Berkeley, 1993

Prenatal Radiation-Induced Limb Defects Mediated by Trp53-Dependent Apoptosis in Mice (2000)

Bing Wang, Harumi Ohyama, Keiko Haginoya, Takeko Odaka, Takeshi Yamada, Isamu Hayata

Wang, B., Ohyama, H., Haginoya, K., Odaka, T., Yamada, T. and Hayata, I. Prenatal Radiation-Induced Limb Defects Mediated by Trp53-Dependent Apoptosis in Mice. We reported previously that in utero...

Adaptive Response in Embryogenesis. III. Relationship to Radiation-Induced Apoptosis and Trp53 Gene Status (2000)

Bing Wang, Harumi Ohyama, Keiko Haginoya, Takeko Odaka, Hiromi Itsukaichi, Osami Yukawa, ...

Wang, B., Ohyama, H., Haginoya, K., Odaka, T., Itsukaichi, H., Yukawa, O., Yamada, T. and Hayata, I. Adaptive Response in Embryogenesis. III. Relationship to Radiation-Induced Apoptosis and Trp53...

Information Operator Scheduling by Genetic Algorithms,” Simulated Evolution and Learning (1999)

Takeshi Yamada, Kazuyuki Yoshimura, Ryohei Nakano

Abstract. In this paper, we discuss an approach to an operator scheduling problem in a large organization over time with the aim of maintaining service quality and reducing total labor costs. We...

HLA-DPB1*0501-associated opticospinal multiple sclerosis: Clinical, neuroimaging and immunogenetic studies (1999)

Yamasaki, Kenji, Horiuchi, Izumi, Minohara, Motozumi, Kawano, Yuji, Ohyagi, Yasumasa, Yamada, Takeshi, ...

In order to clarify the relationship between the clinical phenotype and the human leucocyte antigen (HLA) in multiple sclerosis in Asians, 93 Japanese patients with clinically definite multiple...

Solving the C_sum Permutation Flowshop Scheduling Problem by Genetic Local Search (1998)

Takeshi Yamada, Colin R. Reeves

In this paper a new metaheuristic method is proposed to solve the classical permutation flowshop scheduling problem with the objective of minimizing sum of completion times. The representative...

3D Reconstruction of Skin Surface from Image Sequence (1998)

Takeshi Yamada, Hideo Saito, Shinji Ozawa

This paper proposes a new method for reconstruction a shape of skin surface replica from shading image sequence taken with different light source directions. Since the shading images include shadows...

Genetic Algorithms, Path Relinking and the Flowshop Sequencing Problem (1998)

Colin Reeves, Takeshi Yamada

In a previous paper (Reeves, 1995), a simple genetic algorithm (GA) was developed for finding (approximately) the minimum makespan of the n-job, m-machine permutation flowshop sequencing problem...

Job-Shop Scheduling (1997)

P. J. Fleming, Takeshi Yamada, Ryohei Nakano

Introduction Scheduling is the allocation of shared resources over time to competing activities. It has been the subject of a significant amount of literature in the operations research field....

Genetic Algorithms for Job-Shop Scheduling Problems (1997)

Takeshi Yamada, Ryohei Nakano

this paper. This table is partially cited from [6]. The Conventional GA has only limited success and is outdated. It would be improved by being combined with the GT algorithm and/or the schedule...

Permutation Flowshop Scheduling by Genetic Local Search (1997)

Takeshi Yamada, Colin Reeves

In this paper, the landscape for the permutation flowshop scheduling problem (PFSP) with stochastic local search and a critical block-based neighbourhood structure has been investigated. Numerical...

The performance of Japanese mutual funds (1996)

Cai, Jun, Chan, K. C., Yamada, Takeshi

We analyze the performance of Japanese open-type stock mutual funds for the 1981-1992 period. The results show that, regardless of the performance measures and benchmarks employed, most of the...

The Japanese market for corporate control and managerial incentives (1996)

Kang, Jun-koo, Yamada, Takeshi

We examine bidder returns in Japanese mergers from 1976 to 1990. Using a comprehensive sample of 104 Japanese acquiring firms, we find that shareholders of Japanese bidders experience a significant...

Robust speech recognition with speaker localization by a microphone array (1996)

Takeshi Yamada, Satoshi Nakamura, Kiyohiro Shikano

This paper proposes robust speech recognition with Speaker Localization by a Arrayed Microphone (SLAM) to realize hands-free speech interface in noisy environments. In order to localize a speaker...

Robust Speech Recognition With Speaker Localization By A Microphone Array (1996)

Takeshi Yamada, Satoshi Nakamura, Kiyohiro Shikano

This paper proposes robust speech recognition with Speaker Localization by a Arrayed Microphone (SLAM) to realize hands-free speech interface in noisy environments. In order to localize a speaker...

Scheduling by Genetic Local Search with Multi-Step Crossover (1996)

Takeshi Yamada, Ryohei Nakano

Abstract. In this paper, multi-step crossover (MSX) and a local search method are unified as a single operator called MSXF. MSX and MSXF utilize a neighborhood structure and a distance measure in the...

A Fusion of Crossover and Local Search (1996)

Takeshi Yamada, Ryohei Nakano

Abstract — It is well known that GAs are not well suited for fine-tuning structures that are very close to optimal solutions and that it is essential to incorporate local search methods, such as...

A Fusion of Crossover and Local Search (1996)

Takeshi Yamada, Ryohei Nakano

Abstract — It is well known that GAs are not well suited for fine-tuning structures that are very close to optimal solutions and that it is essential to incorporate local search methods, such as...

Job-shop scheduling by simulated annealing combined with deterministic local search (1996)

Takeshi Yamada, Ryohei Nakano

The Job-Shop Scheduling Problem (JSSP) is one of the most difficult NP-hard combinatorial optimization problems. This paper proposes a new method for solving JSSPs based on simulated annealing (SA),...

Scheduling by Genetic Local Search with Multi-Step Crossover (1996)

Takeshi Yamada, Ryohei Nakano

Abstract. In this paper, multi-step crossover (MSX) and a local search method are unified as a single operator called MSXF. MSX and MSXF utilize a neighborhood structure and a distance measure in the...

The performance of Japanese mutual funds (1996)

Cai, Jun, Chan, K. C., Yamada, Takeshi

We analyze the performance of Japanese open-type stock mutual funds for the 1981-1992 period. The results show that, regardless of the performance measures and benchmarks employed, most of the...

The Japanese market for corporate control and managerial incentives (1996)

Kang, Jun-koo, Yamada, Takeshi

We examine bidder returns in Japanese mergers from 1976 to 1990. Using a comprehensive sample of 104 Japanese acquiring firms, we find that shareholders of Japanese bidders experience a significant...

Job-Shop Scheduling by Simulated Annealing Combined with Deterministic Local Search (1995)

Takeshi Yamada, Ryohei Nakano

: The Job-Shop Scheduling Problem (JSSP) is one of the most difficult NP-hard combinatorial optimization problems. This paper proposes a new method for solving JSSPs based on simulated annealing...

A genetic algorithm with multi-step crossover for job-shop scheduling problems (1995)

Takeshi Yamada, Ryohei Nakano

Genetic Algorithms (GAs) have been designed as general purpose optimization methods. GAs can be uniquely characterized by their population-based search strategies and their operators: mutation,...

A genetic algorithm with multi-step crossover for job-shop scheduling problems (1995)

Takeshi Yamada, Ryohei Nakano

Genetic Algorithms (GAs) have been designed as general purpose optimization methods. GAs can be uniquely characterized by their population-based search strategies and their operators: mutation,...

資産市場の出来高と価格変化の分析 : 最近の展望(田村茂教授退任記念号) (1994)

山田, 健, ヤマダ, タケシ, Yamada, Takeshi

資産市場における出来高と価格変化をめぐる最近の研究の展望を行なう。すでにこの分野ではKarpoff(1987)の展望論文があるため,本論ではそれ以降の発...

Investor heterogeneity, trading volume and asset pricing /--by Takeshi Yamada. (1993)

Yamada, Takeshi.

Thesis (Ph. D. in Business Administration)--University of California, Berkeley, Dec. 1993.

Investor heterogeneity, trading volume, and asset pricing / (1993)

Yamada, Takeshi.

Thesis (Ph. D.)--University of California, Berkeley, 1993.

Performance of Low Specific Speed Pumps (1992)

Kurokawa, Junichi, Yamada, Takeshi, Hiraga, Hiroshi, 黒川, 淳一, クロカワ, ジュンイチ, ...

An efficiency of very low specific speed pump is very low. In order to reveal the reason and to improve efficiency, two kinds of experiments are performed together with the Q3D analysis. One is the...

Genetic algorithms for job-shop scheduling problems (1991)

Takeshi Yamada, Ryohei Nakano

The n×m minimum-makespan general job-shop scheduling problem, hereafter referred to as the JSSP, can be described by a set of n jobs {Ji}1≤j≤n whichistobeprocessedona set of m machines...

Pipe Flov with Viscosity Gradient and Frictional Resistance : 1st Report, Flow of a High Viscosity Fluid in a Heated or Cooled Pipe (1986)

Kurokawa, Junichi, Uchida, Toshiyuki, Adachi, Toshiaki, Yamada, Takeshi, 黒川, 淳一, クロカワ, ジュンイチ, ...

The flow of a highly viscous fluid in a pipe, of which the wall is heated or cooled at a constant temperature, is studied theoretically and experimentally in order to determine the frictional...

粘度変化のある管内流れと摩擦抵抗 : 第1報, 加熱・冷却時の高粘度油の流れ (1986)

黒川, 淳一, 内田, 敏幸, 安立, 利明, 山田, 岳, クロカワ, ジュンイチ, ウチダ, トシユキ, ...

The pipe flow of highly viscous fluid, of which wall is heated or cooled at a constant temperature, was studied theoretically and experimentally in order to determine the frictional resistance of the...

The translocation inhibitor tuberactinomycin binds to nucleic acids and blocks the in vitro assembly of 50S subunits (1980)

Yamada, Takeshi, Teshima, Tadashi, Shiba, Tetsuo, Nierhaus, Knud H.

Binding studies were performed with a [14C]-labeeled derivative of viomycin, tuberactinomycin O (TUM O). TUM O bound to 30S and 50S subunits. The binding component was the RNA, since ribosomal...

Hands-free Speech Recognition Using a Microphone Array

Yamada, Takeshi, 山田, 武志, ヤマダ, タケシ

奈良先端科学技術大学院大学情報科学研究科博士論文、NAIST-IS-DT9661031、1999年3月24日

Inefficient Enhancement of Viral Infectivity and CD4 Downregulation by Human Immunodeficiency Virus Type 1 Nef from Japanese Long-Term Nonprogressors

Tobiume, Minoru, Takahoko, Mikako, Yamada, Takeshi, Tatsumi, Masashi, Iwamoto, Aikichi, Matsuda, Michiyuki

It has been reported that patients infected with nef-defective human immunodeficiency virus type 1 (HIV-1) do not progress to AIDS; however, mutations that abrogate Nef expression are not common in...

Proline 78 Is Crucial for Human Immunodeficiency Virus Type 1 Nef To Down-Regulate Class I Human Leukocyte Antigen

Yamada, Takeshi, Kaji, Naotoshi, Odawara, Takashi, Chiba, Joe, Iwamoto, Aikichi, Kitamura, Yoshihiro

Human immunodeficiency virus type 1 Nef down-regulates human leukocyte antigen class I (HLA-I) in T lymphocytes, and the down-regulation involves the Nef proline-rich domain (PRD) containing four...

Activity of Di-β-Lysyl-Capreomycin IIA and Palmitoyl Tuberactinamine N Against Drug-Resistant Mutants with Altered Ribosomes

Yamada, Takeshi, Teshima, Tadashi, Shiba, Tetsuo

The effects of 61 synthetic tuberactinomycin derivatives on polypeptide synthesis were tested in bacterial cell-free systems. Di-β-lys-capreomycin IIA was more effective than the natural product....

Analysis of Ribosomes from Viomycin-Sensitive and -Resistant Strains of Mycobacterium smegmatis

Yamada, Takeshi, Masuda, Kunitsugu, Shoji, Ko, Hori, Mitsuo

Viomycin-resistant strains were isolated from Mycobacterium smegmatis. Ribosomes were isolated and tested for drug resistance in subcellular systems containing poly(U) as messenger ribonucleic acid....

Pleiotropic Antibiotic Resistance Mutations Associated with Ribosomes and Ribosomal Subunits in Mycobacterium smegmatis

Yamada, Takeshi, Masuda, Kunitsugu, Shoji, Ko, Hori, Mitsuo

Viomycin-resistant strains isolated from Mycobacterium smegmatis demonstrated pleiotropic resistance to tuberactinomycin-N, capreomycin, streptomycin, and kanamycin as a result of mutational...

Altered Ribosomes in Antibiotic-Resistant Mutants of Mycobacterium smegmatis

Yamada, Takeshi, Masuda, Kunitsugu, Mizuguchi, Yasuo, Suga, Kiyoko

Two alleles for viomycin-capreomycin resistance (vic) in Mycobacterium smegmatis affect ribosome structures. One (vicA) affects a component of 50S subunits and the other (vicB) affects a component of...

Priming-Boosting Vaccination with Recombinant Mycobacterium bovis Bacillus Calmette-Guérin and a Nonreplicating Vaccinia Virus Recombinant Leads to Long-Lasting and Effective Immunity

Ami, Yasushi, Izumi, Yasuyuki, Matsuo, Kazuhiro, Someya, Kenji, Kanekiyo, Masaru, Horibata, Shigeo, ...

Virus-specific T-cell responses can limit immunodeficiency virus type 1 (HIV-1) transmission and prevent disease progression and so could serve as the basis for an affordable, safe, and effective...

Diversity, Localization, and Physiological Properties of Filamentous Microbes Belonging to Chloroflexi Subphylum I in Mesophilic and Thermophilic Methanogenic Sludge Granules

Yamada, Takeshi, Sekiguchi, Yuji, Imachi, Hiroyuki, Kamagata, Yoichi, Ohashi, Akiyoshi, Harada, Hideki

We previously reported that the thermophilic filamentous anaerobe Anaerolinea thermophila, which is the first cultured representative of subphylum I of the bacterial phylum Chloroflexi, not only was...

Mycobacterial Codon Optimization Enhances Antigen Expression and Virus-Specific Immune Responses in Recombinant Mycobacterium bovis Bacille Calmette-Guérin Expressing Human Immunodeficiency Virus Type 1 Gag†

Kanekiyo, Masaru, Matsuo, Kazuhiro, Hamatake, Makiko, Hamano, Takaichi, Ohsu, Takeaki, Matsumoto, Sohkichi, ...

Although its potential for vaccine development is already known, the introduction of recombinant human immunodeficiency virus (HIV) genes to Mycobacterium bovis bacille Calmette-Guérin (BCG) has...

Active digestion of sperm mitochondrial DNA in single living sperm revealed by optical tweezers

Nishimura, Yoshiki, Yoshinari, Tomoya, Naruse, Kiyoshi, Yamada, Takeshi, Sumi, Kazuyoshi, Mitani, Hiroshi, ...

In almost all eukaryotes, mitochondrial (mt) genes are transmitted to progeny mainly from the maternal parent. The most popular explanation for this phenomenon is simple dilution of paternal mtDNA,...

Inefficient Enhancement of Viral Infectivity and CD4 Downregulation by Human Immunodeficiency Virus Type 1 Nef from Japanese Long-Term Nonprogressors

Tobiume, Minoru, Takahoko, Mikako, Yamada, Takeshi, Tatsumi, Masashi, Iwamoto, Aikichi, Matsuda, Michiyuki

It has been reported that patients infected with nef-defective human immunodeficiency virus type 1 (HIV-1) do not progress to AIDS; however, mutations that abrogate Nef expression are not common in...

Proline 78 Is Crucial for Human Immunodeficiency Virus Type 1 Nef To Down-Regulate Class I Human Leukocyte Antigen

Yamada, Takeshi, Kaji, Naotoshi, Odawara, Takashi, Chiba, Joe, Iwamoto, Aikichi, Kitamura, Yoshihiro

Human immunodeficiency virus type 1 Nef down-regulates human leukocyte antigen class I (HLA-I) in T lymphocytes, and the down-regulation involves the Nef proline-rich domain (PRD) containing four...

Activity of Di-β-Lysyl-Capreomycin IIA and Palmitoyl Tuberactinamine N Against Drug-Resistant Mutants with Altered Ribosomes

Yamada, Takeshi, Teshima, Tadashi, Shiba, Tetsuo

The effects of 61 synthetic tuberactinomycin derivatives on polypeptide synthesis were tested in bacterial cell-free systems. Di-β-lys-capreomycin IIA was more effective than the natural product....

Analysis of Ribosomes from Viomycin-Sensitive and -Resistant Strains of Mycobacterium smegmatis

Yamada, Takeshi, Masuda, Kunitsugu, Shoji, Ko, Hori, Mitsuo

Viomycin-resistant strains were isolated from Mycobacterium smegmatis. Ribosomes were isolated and tested for drug resistance in subcellular systems containing poly(U) as messenger ribonucleic acid....

Pleiotropic Antibiotic Resistance Mutations Associated with Ribosomes and Ribosomal Subunits in Mycobacterium smegmatis

Yamada, Takeshi, Masuda, Kunitsugu, Shoji, Ko, Hori, Mitsuo

Viomycin-resistant strains isolated from Mycobacterium smegmatis demonstrated pleiotropic resistance to tuberactinomycin-N, capreomycin, streptomycin, and kanamycin as a result of mutational...

Altered Ribosomes in Antibiotic-Resistant Mutants of Mycobacterium smegmatis

Yamada, Takeshi, Masuda, Kunitsugu, Mizuguchi, Yasuo, Suga, Kiyoko

Two alleles for viomycin-capreomycin resistance (vic) in Mycobacterium smegmatis affect ribosome structures. One (vicA) affects a component of 50S subunits and the other (vicB) affects a component of...

Mycobacterial Codon Optimization Enhances Antigen Expression and Virus-Specific Immune Responses in Recombinant Mycobacterium bovis Bacille Calmette-Guérin Expressing Human Immunodeficiency Virus Type 1 Gag†

Kanekiyo, Masaru, Matsuo, Kazuhiro, Hamatake, Makiko, Hamano, Takaichi, Ohsu, Takeaki, Matsumoto, Sohkichi, ...

Although its potential for vaccine development is already known, the introduction of recombinant human immunodeficiency virus (HIV) genes to Mycobacterium bovis bacille Calmette-Guérin (BCG) has...

Priming-Boosting Vaccination with Recombinant Mycobacterium bovis Bacillus Calmette-Guérin and a Nonreplicating Vaccinia Virus Recombinant Leads to Long-Lasting and Effective Immunity

Ami, Yasushi, Izumi, Yasuyuki, Matsuo, Kazuhiro, Someya, Kenji, Kanekiyo, Masaru, Horibata, Shigeo, ...

Virus-specific T-cell responses can limit immunodeficiency virus type 1 (HIV-1) transmission and prevent disease progression and so could serve as the basis for an affordable, safe, and effective...

Diversity, Localization, and Physiological Properties of Filamentous Microbes Belonging to Chloroflexi Subphylum I in Mesophilic and Thermophilic Methanogenic Sludge Granules

Yamada, Takeshi, Sekiguchi, Yuji, Imachi, Hiroyuki, Kamagata, Yoichi, Ohashi, Akiyoshi, Harada, Hideki

We previously reported that the thermophilic filamentous anaerobe Anaerolinea thermophila, which is the first cultured representative of subphylum I of the bacterial phylum Chloroflexi, not only was...

Active digestion of sperm mitochondrial DNA in single living sperm revealed by optical tweezers

Nishimura, Yoshiki, Yoshinari, Tomoya, Naruse, Kiyoshi, Yamada, Takeshi, Sumi, Kazuyoshi, Mitani, Hiroshi, ...

In almost all eukaryotes, mitochondrial (mt) genes are transmitted to progeny mainly from the maternal parent. The most popular explanation for this phenomenon is simple dilution of paternal mtDNA,...

Hands-free Speech Recognition Using a Microphone Array

Yamada, Takeshi, 山田, 武志, ヤマダ, タケシ

奈良先端科学技術大学院大学情報科学研究科博士論文、NAIST-IS-DT9661031、1999年3月24日

Asset Price Shocks, Financial Constraint, and Investment: Evidence from Japan

Vidhan K. Goyal, Takeshi Yamada

This paper examines investment spending of Japanese firms around the “asset price bubble” in the late-1980s and makes three contributions to our understanding of how stock valuations affect...

Recombinant Mycobacterium bovis Bacillus Calmette-Guérin Secreting Merozoite Surface Protein 1 (MSP1) Induces Protection against Rodent Malaria Parasite Infection Depending on MSP1-stimulated Interferon γ and Parasite-specific Antibodies

Matsumoto, Sohkichi, Yukitake, Hideharu, Kanbara, Hiroji, Yamada, Takeshi

The merozoite surface protein 1 (MSP1) has emerged as a leading malaria vaccine candidate at the erythrocytic stage. Recombinant bacillus Calmette-Guérin (rBCG), which expressed a COOH-terminal...

The Impacts of Financial Deregulation upon Trading Efficiency and the Levels of Risk and Return of Japanese Banks.

Pettway, Richard H, Tapley, T Craig, Yamada, Takeshi

Japanese banks are very large and were rigidly controlled until financial deregulation began in the late 1970s. This paper measures the impact of deregulation upon the trading efficiency and the...

The Effect of Bank Relations on Investment Decisions: An Investigation of Japanese Takeover Bids

Jun-Koo Kang, Anil Shivdasani, Takeshi Yamada

We study 154 domestic mergers in Japan during 1977 to 1993. In contrast to U.S. evidence, mergers are viewed favorably by investors of acquiring firms. We document a two-day acquirer abnormal return...

How do Individual, Institutional, and Foreign Investors Win and Lose in Equity Trades? Evidence from Japan-super-

KEE-HONG BAE, TAKESHI YAMADA, KEIICHI ITO

We investigate the gains and losses from equity trades of individual investors, various institutional investors, and foreign investors in the Tokyo Stock Exchange. We develop a trade-weighted...

The Performance of Japanese Mutual Funds.

Cai, Jun, Chan, K C, Yamada, Takeshi

We analyze the performance of Japanese opentype stock mutual funds for the 1981-1992 period. The results show that, regardless of the performance measures and benchmarks employed, most of the...

Interaction of investor trades and market volatility: Evidence from the Tokyo Stock Exchange

Bae, Kee-Hong, Yamada, Takeshi, Ito, Keiichi

This paper examines the relation between market volatility and investor trades by identifying who supplies and demands market liquidity on the Tokyo Stock Exchange. Because the different trading...

Asset Price Shocks, Financial Constraints, and Investment: Evidence from Japan

Vidhan K. Goyal, Takeshi Yamada

We examine corporate investment spending around the asset price bubble in Japan in the late 1980s and make three contributions to our understanding of how stock valuations affect investment. First,...

血淸カルシウム微量比色定量法

山田, 猛, Yamada, Takeshi

Two new micro-methods for estimation of calcium are described, which can be carried out with 0.1ml. of serum. Previous deproteinization is unnecessary. In the first method the precipitated calcium...

New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum

Yamada, Takeshi, Muroga, Yasuhide, Tanaka, Reiko

Seco-chaetomugilins A and D were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on...