Yohei Hasegawa, Shohei Abe, Shunsuke Kurotaki, Vu Manh Tuan, Naohiro Katsura, Takuro Nakamura, ...
Dynamically Reconfigurable Processor (DRP) developed by NEC Electronics is a coarse grain reconfigurable processor that selects a datapath called a context from the on-chip repository of sixteen...
Kawamura-Saito, Miho, Yamazaki, Yukari, Kaneko, Keiko, Kawaguchi, Noriyoshi, Kanda, Hiroaki, Mukai, Hiroyuki, ...
Ewing's family tumors (EFTs) are highly malignant tumors arising from bone and soft tissues that exhibit EWS–FLI1 or variant EWS–ETS gene fusions in more than 85% of the cases. Here we show that...
Kawamura-Saito, Miho, Yamazaki, Yukari, Kaneko, Keiko, Kawaguchi, Noriyoshi, Kanda, Hiroaki, Mukai, Hiroyuki, ...
Ewing's family tumors (EFTs) are highly malignant tumors arising from bone and soft tissues that exhibit EWS-FLI1 or variant EWS-ETS gene fusions in more than 85% of the cases. We show here that CIC,...
Nakamura, Takuro, Yamazaki, Yukari, Saiki, Yuriko, Moriyama, Masatsugu, Largaespada, David A., Jenkins, Nancy A., ...
Evi9 is a common site of retroviral integration in BXH2 murine myeloid leukemias. Here we show that Evi9 encodes a novel zinc finger protein with three tissue-specific isoforms: Evi9a (773 amino...
Tsuruyama, Tatsuaki, Nakamura, Takuro, Jin, Guang, Ozeki, Munetaka, Yamada, Yoshihiro, Hiai, Hiroshi
We found that the second intron of Stat5a was one of the common integration sites of the endogenous ecotropic murine leukemia virus, i.e., SL/Kh virus integration-1 (Svi1), in early pre-B lymphomas...
NUP98–HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
Kroon, Evert, Thorsteinsdottir, Unnur, Mayotte, Nadine, Nakamura, Takuro, Sauvageau, Guy
Here we describe hemopoietic chimeras serving as a mouse model for NUP98–HOXA9-induced leukemia, which reproduced several of the phenotypes observed in human disease. Mice transplanted with bone...
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals
Hisa, Tomoyuki, Spence, Sally E, Rachel, Rivka A, Fujita, Masami, Nakamura, Takuro, Ward, Jerrold M, ...
Meis1 and Hoxa9 expression is upregulated by retroviral integration in murine myeloid leukemias and in human leukemias carrying MLL translocations. Both genes also cooperate to induce leukemia in a...
Nakamura, Takuro, Yamazaki, Yukari, Saiki, Yuriko, Moriyama, Masatsugu, Largaespada, David A., Jenkins, Nancy A., ...
Evi9 is a common site of retroviral integration in BXH2 murine myeloid leukemias. Here we show that Evi9 encodes a novel zinc finger protein with three tissue-specific isoforms: Evi9a (773 amino...
Tsuruyama, Tatsuaki, Nakamura, Takuro, Jin, Guang, Ozeki, Munetaka, Yamada, Yoshihiro, Hiai, Hiroshi
We found that the second intron of Stat5a was one of the common integration sites of the endogenous ecotropic murine leukemia virus, i.e., SL/Kh virus integration-1 (Svi1), in early pre-B lymphomas...
NUP98–HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
Kroon, Evert, Thorsteinsdottir, Unnur, Mayotte, Nadine, Nakamura, Takuro, Sauvageau, Guy
Here we describe hemopoietic chimeras serving as a mouse model for NUP98–HOXA9-induced leukemia, which reproduced several of the phenotypes observed in human disease. Mice transplanted with bone...
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals
Hisa, Tomoyuki, Spence, Sally E, Rachel, Rivka A, Fujita, Masami, Nakamura, Takuro, Ward, Jerrold M, ...
Meis1 and Hoxa9 expression is upregulated by retroviral integration in murine myeloid leukemias and in human leukemias carrying MLL translocations. Both genes also cooperate to induce leukemia in a...
A DNA transposon-based approach to validate oncogenic mutations in the mouse
Su, Qin, Prosser, Haydn M., Campos, Lia S., Ortiz, Mariaestela, Nakamura, Takuro, Warren, Madhuri, ...
Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified...