Temporal lobe epilepsy after experimental prolonged febrile seizures: prospective analysis (2006)
Dubé, Céline, Richichi, Cristina, Bender, Roland A., Chung, Grace, Litt, Brian, Baram, Tallie Z.
Experimental prolonged febrile seizures (FS) lead to structural and molecular changes that promote hippocampal hyperexcitability and reduce seizure threshold to further convulsants. However, whether...
Brewster, Amy L., Chen, Yuncai, Bender, Roland A., Yeh, Amy, Shigemoto, Ryuichi, Baram, Tallie Z.
The properties of the hyperpolarization-activated current (Ih) and its roles in hippocampal network function evolve radically during development. Because Ih is conducted by the...
Brewster, Amy L., Chen, Yuncai, Bender, Roland A., Yeh, Amy, Shigemoto, Ryuichi, Baram, Tallie Z.
The properties of the hyperpolarization-activated current (Ih) and its roles in hippocampal network function evolve radically during development. Because Ih is conducted by the...
Temporal lobe epilepsy after experimental prolonged febrile seizures: prospective analysis (2006)
Dubé, Céline, Richichi, Cristina, Bender, Roland A., Chung, Grace, Litt, Brian, Baram, Tallie Z.
Experimental prolonged febrile seizures (FS) lead to structural and molecular changes that promote hippocampal hyperexcitability and reduce seizure threshold to further convulsants. However, whether...
Brewster, Amy L., Chen, Yuncai, Bender, Roland A., Yeh, Amy, Shigemoto, Ryuichi, Baram, Tallie Z.
The properties of the hyperpolarization-activated current (Ih) and its roles in hippocampal network function evolve radically during development. Because Ih is conducted by the...
Brewster, Amy L., Chen, Yuncai, Bender, Roland A., Yeh, Amy, Shigemoto, Ryuichi, Baram, Tallie Z.
The properties of the hyperpolarization-activated current (Ih) and its roles in hippocampal network function evolve radically during development. Because Ih is conducted by the...
Brunson, Kristen L., Eghbal-Ahmadi, Mariam, Bender, Roland, Chen, Yuncai, Baram, Tallie Z.
Stress early in postnatal life may result in long-term memory deficits and selective loss of hippocampal neurons. The mechanisms involved are poorly understood, but they may involve molecules and...
Roozendaal, Benno, Brunson, Kristen L., Holloway, Brian L., McGaugh, James L., Baram, Tallie Z.
It is well established that adrenal stress hormone-induced activation of the basolateral complex of the amygdala (BLA) influences memory consolidation. The present experiments investigated the...
Chen, Yuncai, Bender, Roland A., Brunson, Kristen L., Pomper, Jörn K., Grigoriadis, Dimitri E., Wurst, Wolfgang, ...
The interplay of environmental and genetic factors in the developmental organization of the hippocampus has not been fully elucidated. The neuropeptide corticotropin-releasing factor (CRF) is...
Brunson, Kristen L., Eghbal-Ahmadi, Mariam, Bender, Roland, Chen, Yuncai, Baram, Tallie Z.
Stress early in postnatal life may result in long-term memory deficits and selective loss of hippocampal neurons. The mechanisms involved are poorly understood, but they may involve molecules and...
Roozendaal, Benno, Brunson, Kristen L., Holloway, Brian L., McGaugh, James L., Baram, Tallie Z.
It is well established that adrenal stress hormone-induced activation of the basolateral complex of the amygdala (BLA) influences memory consolidation. The present experiments investigated the...
Chen, Yuncai, Bender, Roland A., Brunson, Kristen L., Pomper, Jörn K., Grigoriadis, Dimitri E., Wurst, Wolfgang, ...
The interplay of environmental and genetic factors in the developmental organization of the hippocampus has not been fully elucidated. The neuropeptide corticotropin-releasing factor (CRF) is...
New Roles for Interleukin-1 Beta in the Mechanisms of Epilepsy
Vezzani, Annamaria, Baram, Tallie Z
The mechanisms that transform a normal brain to an epileptic one are not fully understood. Interleukin-1 beta (IL-1β) contributes to neuronal degeneration observed in several neurological disorders...
A Novel Mouse Model for Acute and Long-Lasting Consequences of Early Life Stress
Rice, Courtney J., Sandman, Curt A., Lenjavi, Mohammed R., Baram, Tallie Z.
Chronic early-life stress (ES) exerts profound acute and long-lasting effects on the hypothalamic-pituitary-adrenal system, with relevance to cognitive function and affective disorders. Our ability...
The Pathways from Mother's Love to Baby's Future
Korosi, Aniko, Baram, Tallie Z.
Together with genetic factors, early-life experience governs the expression and function of stress-related genes throughout life. This, in turn, contributes to either resilience or vulnerability to...
Kerjan, Géraldine, Koizumi, Hiroyuki, Han, Edward B., Dubé, Celine M., Djakovic, Stevan N., Patrick, Gentry N., ...
Mutations in doublecortin (DCX) are associated with intractable epilepsy in humans, due to a severe disorganization of the neocortex and hippocampus known as classical lissencephaly. However, the...