Wang, Huiping, Kong, Fanrong, Sorrell, Tania C, Wang, Bin, McNicholas, Paul, Pantarat, Namfon, ...
Abstract Background Amino acid substitutions in the target enzyme Erg11p of azole antifungals contribute to clinically-relevant azole resistance in Candida albicans . A simple molecular method for...
Determinants of mortality in non-neutropenic ICU patients with candidaemia (2009)
Marriott, Deborah JE, Playford, E Geoffrey, Chen, Sharon, Slavin, Monica, Nguyen, Quoc, Ellis, David, ...
Abstract Introduction Candidaemia in critically-ill intensive care unit (ICU) patients is associated with high crude mortality. Determinants of mortality – particularly those amenable to potential...
Malik, Richard, Kuhn, Till, Daniel, Heide-Marie, Somorjai, Ray L., Dolenko, Brion, ...
Bacterial meningitis is an acute disease with high mortality that is reduced by early treatment. Identification of the causative microorganism by culture is sensitive but slow. Large volumes of...
Malik, Richard, Kühn, Till, Daniel, Heide-Marie, Somorjai, Ray L, Dolenko, Brion, ...
Bacterial meningitis is an acute disease with high mortality that is reduced by early treatment. Identification of the causative microorganism by culture is sensitive but slow. Large volumes of...
Blyth, Christopher C., Chen, Sharon C. A., Slavin, M., Serena, Carol, Nguyen, Quoc, Marriott, D., ...
Copyright © 2009 by the American Academy of Pediatrics.
Blyth, Christopher C., Chen, Sharon C. A., Slavin, M., Serena, Carol, Nguyen, Quoc, Marriott, D., ...
Copyright © 2009 by the American Academy of Pediatrics.
Obando, D., Pantarat, Namfon, Handke, Rosemary, Koda, Yasuko, Widmer, F., Djordjevic, Julianne T., ...
A series of bis(alkylpyridinium)alkanes with a twelve carbon spacer between the positive charges was synthesised and their antifungal activity has been investigated. Compounds with 2-pentyl,...
Obando, D., Pantarat, Namfon, Handke, Rosemary, Koda, Yasuko, Widmer, F., Djordjevic, Julianne T., ...
A series of bis(alkylpyridinium)alkanes with a twelve carbon spacer between the positive charges was synthesised and their antifungal activity has been investigated. Compounds with 2-pentyl,...
Recommendations for the treatment of established fungal infections (2008)
Thursky, Karin, Playford, E. Geoffrey, Seymour, John F., Sorrell, Tania C., Ellis, David Hedley, Guy, S. D., ...
© 2008 The Authors Journal compilation. Copyright © 2008 John Wiley & Sons, Inc
Recommendations for the treatment of established fungal infections (2008)
Thursky, Karin, Playford, E. Geoffrey, Seymour, John F., Sorrell, Tania C., Ellis, David Hedley, Guy, S. D., ...
© 2008 The Authors Journal compilation. Copyright © 2008 John Wiley & Sons, Inc
Playford, E. Geoffrey, Marriott, D., Nguyen, Quoc, Chen, Sharon C. A., Ellis, David Hedley, Slavin, M., ...
E. Geoffrey Playford, Deborah Marriott, Quoc Nguyen, Sharon Chen, David Ellis, Monica Slavin, Tania Sorrell
Playford, E. Geoffrey, Marriott, D., Nguyen, Quoc, Chen, Sharon C. A., Ellis, David Hedley, Slavin, M., ...
E. Geoffrey Playford, Deborah Marriott, Quoc Nguyen, Sharon Chen, David Ellis, Monica Slavin, Tania Sorrell
Playford, E. Geoffrey, Webster, Angela C., Sorrell, Tania C., Craig, Jonathan C.
Objectives: This study aims to systematically identify and summarize the effects of antifungal prophylaxis in non-neutropenic critically ill adult patients on all-cause mortality and the incidence of...
Identification of Cryptococcus neoformans by Magnetic Resonance Spectroscopy (2002)
Sorrell, Tania C., Dzendrowskyj, Theresa, Malik, Richard, Mountford, Carolyn
A prospective study of adverse reactions associated with vancomycin therapy (1985)
Sorrell, Tania C., Collignon, Peter J.
A prospective evaluation of the efficacy and safety of vancomycin was conducted in 54 consecutive patients over a 16-month period. Vancomycin was curative in 95% of 43 patients with proven...
Effectiveness of mezlocillin in female genital tract infections (1982)
Marshall, John R., Chow, Anthony W., Sorrell, Tania C.
One hundred and twenty-six patients with female genital tract infections were treated with intravenous mezlocillin (16 g/day) in a prospective, multicentre, clinical trial. Clindamycin (2 g/day) was...
Latouche, G. Nicolas, Huynh, Matthew, Sorrell, Tania C., Meyer, Wieland
Cryptococcus neoformans is a pathogenic yeast that is currently divided into three varieties, five serotypes, and eight molecular types. The following report describes the use of PCR-restriction...
Himmelreich, Uwe, Somorjai, Ray L., Dolenko, Brion, Lee, Ok Cha, Daniel, Heide-Marie, Murray, Ronan, ...
Nuclear magnetic resonance (NMR) spectra were acquired from suspensions of clinically important yeast species of the genus Candida to characterize the relationship between metabolite profiles and...
Widmer, Fred, Wright, Lesley C., Obando, Daniel, Handke, Rosemary, Ganendren, Ranjini, Ellis, David H., ...
The alkyl phosphocholine drug miltefosine is structurally similar to natural substrates of the fungal virulence determinant phospholipase B1 (PLB1), which is a potential drug target. We determined...
Siafakas, A. Rosemary, Wright, Lesley C., Sorrell, Tania C., Djordjevic, Julianne T.
Lipid rafts have been identified in the membranes of mammalian cells, the yeast Saccharomyces cerevisiae, and the pathogenic fungus Candida albicans. Formed by a lateral association of sphingolipids...
Playford, E. Geoffrey, Kong, Fanrong, Sun, Ying, Wang, Hui, Halliday, Catriona, Sorrell, Tania C.
We report on a reverse line blot (RLB) assay, utilizing fungal species-specific oligonucleotide probes to hybridize with internal transcribed spacer 2 region sequences amplified using a nested...
Latouche, G. Nicolas, Huynh, Matthew, Sorrell, Tania C., Meyer, Wieland
Cryptococcus neoformans is a pathogenic yeast that is currently divided into three varieties, five serotypes, and eight molecular types. The following report describes the use of PCR-restriction...
Himmelreich, Uwe, Somorjai, Ray L., Dolenko, Brion, Lee, Ok Cha, Daniel, Heide-Marie, Murray, Ronan, ...
Nuclear magnetic resonance (NMR) spectra were acquired from suspensions of clinically important yeast species of the genus Candida to characterize the relationship between metabolite profiles and...
Widmer, Fred, Wright, Lesley C., Obando, Daniel, Handke, Rosemary, Ganendren, Ranjini, Ellis, David H., ...
The alkyl phosphocholine drug miltefosine is structurally similar to natural substrates of the fungal virulence determinant phospholipase B1 (PLB1), which is a potential drug target. We determined...
Playford, E. Geoffrey, Kong, Fanrong, Sun, Ying, Wang, Hui, Halliday, Catriona, Sorrell, Tania C.
We report on a reverse line blot (RLB) assay, utilizing fungal species-specific oligonucleotide probes to hybridize with internal transcribed spacer 2 region sequences amplified using a nested...
Siafakas, A. Rosemary, Wright, Lesley C., Sorrell, Tania C., Djordjevic, Julianne T.
Lipid rafts have been identified in the membranes of mammalian cells, the yeast Saccharomyces cerevisiae, and the pathogenic fungus Candida albicans. Formed by a lateral association of sphingolipids...
Coen, Muireann, Bodkin, Jennifer, Power, Damla, Bubb, William A., Himmelreich, Uwe, Kuchel, Philip W., ...
Drug-induced inhibition of fungal growth is used in the diagnostic laboratory to predict therapeutic efficacy but is relatively slow, and determination of endpoints can be problematic. Nuclear...
Wright, Lesley C., Santangelo, Rosemary M., Ganendren, Ranjini, Payne, Jackie, Djordjevic, Julianne T., Sorrell, Tania C.
Cryptococci survive and replicate within macrophages and can use exogenous arachidonic acid for the production of eicosanoids. Phospholipase B1 (PLB1) has a putative, but uninvestigated, role in...
Tong, Zhongsheng, Widmer, Fred, Sorrell, Tania C., Guse, Zofia, Jolliffe, Katrina A., Halliday, Catriona, ...
The susceptibilities of 77 dermatophytes to miltefosine (MI), 1,12-bis(4-pentylpyridinium)dodecane (PYR), 1,12-bis(tributylammonium)dodecane (AM), itraconazole (ITC), terbinafine (TRB), and...
Zeng, Xianyu, Kong, Fanrong, Halliday, Catriona, Chen, Sharon, Lau, Anna, Playford, Geoffrey, ...
We evaluated a combined panfungal PCR-reverse line blot (RLB) hybridization assay based on internal transcribed spacer 1 (ITS1) and ITS2 region polymorphisms to identify 159 Candida, Cryptococcus...
Zhou, Xiaoyong, Kong, Fanrong, Sorrell, Tania C., Wang, Hui, Duan, Yiqun, Chen, Sharon C. A.
A sensitive rolling-circle amplification (RCA)-based method utilizing species-specific padlock probes targeted to the internal transcribed spacer 2 region of the fungal ribosomal DNA gene complex was...
Delhaes, Laurence, Harun, Azian, Chen, Sharon C.A., Nguyen, Quoc, Slavin, Monica, Heath, Christopher H., ...
Molecular typing showed genetic diversity, dismissed 2 suspected outbreaks of scedosporiosis, and identified multiple strains of the newly described species S. aurantiacum.
Lau, Anna, Sorrell, Tania C., Chen, Sharon, Stanley, Keith, Iredell, Jonathan, Halliday, Catriona
We describe the first development and evaluation of a rapid multiplex tandem PCR (MT-PCR) assay for the detection and identification of fungi directly from blood culture specimens that have been...
Himmelreich, Uwe, Malik, Richard, Kühn, Till, Daniel, Heide-Marie, Somorjai, Ray L., Dolenko, Brion, ...
Colony Multiplex-Tandem PCR for Rapid, Accurate Identification of Fungal Cultures▿
Lau, Anna, Sorrell, Tania C., Lee, OkCha, Stanley, Keith, Halliday, Catriona
We developed a multiplex tandem PCR (MT-PCR) assay for the rapid identification of 16 fungi directly from culture. MT-PCR results were concordant with phenotypic identification for all cultures...
Kong, Fanrong, Chen, Sharon C.A, Chen, Xiaoyou, Sintchenko, Vitali, Halliday, Catriona, Cai, Lin, ...
16S rDNA sequence analysis is the most accurate method for definitive species identification of nocardiae. However, conflicting results can be found due to sequence errors in gene databases. This...