Tim J. Carver, Tanya Vavouri, Martin Frith, Martin J. Bishop, Greg Elgar
Theatre is a web-based computing system designed for the comparative analysis of genomic sequences, especially with respect to motifs likely to be involved in the regulation of gene expression....
Semple, Jennifer I, Vavouri, Tanya, Lehner, Ben
Abstract Background The functions of a eukaryotic cell are largely performed by multi-subunit protein complexes that act as molecular machines or information processing modules in cellular networks....
Vavouri, Tanya, Walter, Klaudia, Gilks, Walter R, Lehner, Ben, Elgar, Greg
Abstract Background The human genome contains thousands of non-coding sequences that are often more conserved between vertebrate species than protein-coding exons. These highly conserved non-coding...
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development (2005)
Adam Woolfe, Martin Goodson, Debbie K. Goode, Phil Snell, Gayle K. McEwen, Tanya Vavouri, ...
Highly conserved non-coding sequences in vertebrate genomes are frequently located around genes involved in development and can direct tissue-specific gene expression in functional assays.
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development (2005)
Adam Woolfe, Martin Goodson, Debbie K. Goode, Phil Snell, Gayle K. McEwen, Tanya Vavouri, ...
In addition to protein coding sequence, the human genome contains a significant amount of regulatory DNA, the identification of which is proving somewhat recalcitrant to both in silico and functional...
Edwards, Yvonne J. K., Carver, Tim J., Vavouri, Tanya, Frith, Martin, Bishop, Martin J., Elgar, Greg
Theatre is a web-based computing system designed for the comparative analysis of genomic sequences, especially with respect to motifs likely to be involved in the regulation of gene expression....
Theatre: a software tool for detailed comparative analysis and visualization of genomic sequence
Edwards, Yvonne J. K., Carver, Tim J., Vavouri, Tanya, Frith, Martin, Bishop, Martin J., Elgar, Greg
Theatre is a web-based computing system designed for the comparative analysis of genomic sequences, especially with respect to motifs likely to be involved in the regulation of gene expression....
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development
Woolfe, Adam, Goodson, Martin, Goode, Debbie K, Snell, Phil, McEwen, Gayle K, Vavouri, Tanya, ...
In addition to protein coding sequence, the human genome contains a significant amount of regulatory DNA, the identification of which is proving somewhat recalcitrant to both in silico and functional...
Ancient duplicated conserved noncoding elements in vertebrates: A genomic and functional analysis
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
Theatre: a software tool for detailed comparative analysis and visualization of genomic sequence
Edwards, Yvonne J. K., Carver, Tim J., Vavouri, Tanya, Frith, Martin, Bishop, Martin J., Elgar, Greg
Theatre is a web-based computing system designed for the comparative analysis of genomic sequences, especially with respect to motifs likely to be involved in the regulation of gene expression....
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development
Woolfe, Adam, Goodson, Martin, Goode, Debbie K, Snell, Phil, McEwen, Gayle K, Vavouri, Tanya, ...
In addition to protein coding sequence, the human genome contains a significant amount of regulatory DNA, the identification of which is proving somewhat recalcitrant to both in silico and functional...
Ancient duplicated conserved noncoding elements in vertebrates: A genomic and functional analysis
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
Vavouri, Tanya, Walter, Klaudia, Gilks, Walter R, Lehner, Ben, Elgar, Greg
Invertebrate conserved noncoding elements (CNEs) are associated with the same core set of genes as vertebrate CNEs, and may reflect the parallel evolution of enhancers in the gene regulatory networks...